CRISPRi on #Bdellovibrio to study essential genes 🤗🤩 #MicroSky

A new chapter begins! Happy to be back at the @pasteur.fr , a place that feels like home. Excited for the journey ahead and all the science to come!

🎓 Applications for Institut Pasteur's PhD programs open Sept 1-Oct 20, 2025 for October 2026 entry. Apply to up to 4 projects across 6 programs: PPU, PPU-IMAGINE @institutimagine.bsky.social, [email protected], PPU-EID @upcite.bsky.social & more 🧬 Register now ✍️ www.pasteur.fr/en/education...

Many spores from the Firmicutes group are decorated with hair-like structures. Since the 60s, they remained a mystery. @remaut-lab.bsky.social named these fibres ENdospore Appendages (ENAs). Using Cryo-ID, we report the identity, structure and function of F-ENA. www.nature.com/articles/s41...

Thrilled to see our work published in @embojournal.org #asgard #archaea #cytoskeleton #tubulin #FtsZ We sincerely appreciate the constructive peer review and the reviewers’ thoughtful, supportive feedback, which greatly strengthened our work.

Excited to share our newly book chapter on using #miniTurbo proximity labeling in #bacteria We wrote it as a hands-on guide for anyone looking to get started with this approach. Congrats to @coralietesseur.bsky.social and Ophélie Remy 👏 @lalouxlab.bsky.social link.springer.com/protocol/10....

Happy to see the final version out! Cryo-EM structure of the PS2 S-layer in Corynebacterium 🔬! We show it provides mechanical support to the cell wall and assembles at the poles in coordination with PG. It can also be used for covalent surface display. www.pnas.org/doi/10.1073/... #microsky

Our review on contact-dependent #predation is now out ! We define predation processes and describe how predators kill and eat their prey 😈 Repost appreciated ❤️

Bacterial cell wall & periplasm paradigm shift - important read #MicroSky www.nature.com/articles/s41...

#MicroSky Summer read! Predatory bacteria kill and eat other bacteria. Their deadly actions come in many flavors, often via direct physical contact between predator & prey 🧛 How do they do it? Our review 📖 @coralietesseur.bsky.social @ysantin.bsky.social www.sciencedirect.com/science/arti...

New review from our lab! Compartmentalization during bacterial spore formation. Focusing on latest discoveries in Bacillus subtilis #subtiwiki www.sciencedirect.com/science/arti...

Folddisco finds similar (dis)continuous 3D motifs in large protein structure databases. Its efficient index enables fast uncharacterized active site annotation, protein conformational state analysis and PPI interface comparison. 1/9🧶🧬 📄 www.biorxiv.org/content/10.1... 🌐 search.foldseek.com/folddisco

You thought all OMPs were trimeric? 🧐 Not in our predator B. bacteriovorus! 🦠 Excited to have contributed to this great collab with the Lovering lab on this intriguing protein. @lalouxlab.bsky.social 👉 Paper here! www.nature.com/articles/s41... #BacterialPredation #Bdellovibrio #StructuralBiology

a treat for fans of 𝘉𝘢𝘤𝘪𝘭𝘭𝘶𝘴 𝘴𝘶𝘣𝘵𝘪𝘭𝘪𝘴 and its intriguing spores 👇 #MicroSky

Running Phenix and stuck? Now you can ask the new Phenix chatbot anything from the 600-page tutorial about how to run any program. Big thanks to Tom Willinger for making this happen! Try it out: phenix-online.org/version_docs...

🎶 Science meets creativity with TuberKiller! Yaëlle Wormser, PhD student featured in the My PhD at the Institut Pasteur series, raps her tuberculosis research. Discover how music and science collide to make research unforgettable! 👏 🎧 TuberKiller is also available on Spotify! @pasteur.fr

Excited to share our latest review! Check it out to see what we know so far about how Staphylococcus aureus coordinates key processes during its cell cycle

How does your favorite species elongate? 🧵 "Phenotypic plasticity in bacterial elongation among closely related species". Happy to see this paper in print @natcomms.nature.com. Nice work by @mariedelaby.bsky.social, Liu Yang et al. See original 🧵, different colours, same data and conclusions.

The nucleoid of rapidly growing E. coli 🦠 localizes close to the inner membrane & is organized by transcription, translation, & cell geometry @michriscopy.bsky.social @uni-wuerzburg.de @heilemannlab.bsky.social @goetheuni.bsky.social #microbiology

The archaeal S-layer is not only pretty, it also carries crucial cellular functions, and the list keeps growing! @sshamphavi.bsky.social @marleenvw.bsky.social @archaellum.bsky.social and I wrote a little sheath sheet (+10 pts if you got the pun) 📖 Curr Opin Cell Biol 🔗 doi.org/10.1016/j.ce...

I’m thrilled to finally share this preprint! It contains a WOW Cryo-EM structure (likely one of the strongest protein fibers known to man 🤯), but we’ve also untangled its biological function: a novel type of virulence factor💀! www.researchsquare.com/article/rs-6...

📖 New publication from the TacC team at MMSB! Congratulations to Nathan Fraikin et al.! @nfrk92.bsky.social @agathe-couturier.bsky.social

Our review on Z-ring placement mechanisms in cocci is out! This was a fun one to write! #Microsky 🦠🧫

New preprint from the @remaut-lab.bsky.social ! Happy to share our latest work on a new member of the ENA family, protein fibers found on the spore’s surface. Using CryoID @mikesleutel.bsky.social identified F-ENA in BTK. The paper dives deep into its structure analysis by integrating X-ray and AF3

Using Bacillus subtilis as a model organism, this #JBacteriology review describes the signal transduction pathway & events leading to spore germination, incorporating the latest findings on transcription and translation likely detected during germination. asm.social/2g2

Our second paper of the week is also out!🥳 Dive into the interface of S-layers and nanobodies in our companion paper! In collaboration with Alex Pak (Colorado, USA), we explore how nanobodies destabilize S-layers using machine learning and molecular dynamics.

Finally out!🤩 if you were wondering how the Sap S-layer of B. anthracis looks, we have the answer! We've used an integrative structural biology approach to solve the atomic details. I wanted to make a thread highlighting the main results, but @mishakudryashev.bsky.social already did a nice job👇

Excited to share that our paper is now out in ⁦Nature Microbiology @natureportfolio.bsky.social! We characterize a positive mechanism for Z ring placement in S. aureus governed by the proteins PcdA/DivIVA, and its implication during infection in a mouse model #Microsky rdcu.be/dYmdC

Bacterial cell surface starter pack ! Trying to make it easier to find people with the same love for bacterial membranes and whatever goes in and through them. Leave a comment if you want to be added go.bsky.app/KfHSqvt