What if even the core of bacterial nanomachines wasn’t static? We found that the T3SS core protein SctD in Yersinia dynamically exchanges subunits — and this flexibility is essential for proper assembly & function. 🔗 www.nature.com/articles/s41... @kit.edu @t3sss.bsky.social

#microsky journals.asm.org/doi/10.1128/...

📢 Postdoc position: Biochemistry & Bacterial cell biology in our group at Marburg University, Germany, funded by the ERC Advanced Grant "C-SWITCH" 🔗More information at shorturl.at/OlvlL 📅Deadline: Nov 30, 2025 Please repost. #Postdoc

An Asgard archaeon containing internal membrane compartments!! 😯 This will reshape our understanding of how the eukaryotic endomembrane system originated. Congrats to @buzzbaum.bsky.social, @tbharat-lab.bsky.social and all ppl involved! www.biorxiv.org/content/10.1...

When asked to draw a scientist, school-age kids in the United States are increasingly sketching women, according to a study from 2018. Read more on #STEMSTEAMDay: https://scim.ag/4qFrPON

As mentioned, here is the preprint by Jensen and @viollierpat.bsky.social on the in situ structure of the Tad pilus. www.biorxiv.org/content/10.1.... Nice work and great to see that we are seeing the same thing! Our preprint: www.biorxiv.org/content/10.1... #microsky

Our latest work is out in PNAS!🎉 We show that nonequilibrium polysome dynamics help drive sister chromosomes apart. The closing division septum also contributes via steric interactions.👇 www.pnas.org/doi/10.1073/... #MicroSky #Microbiology #Biophysics #CellBiology

A Sharon Begley byline, almost 5 years after her death. Upon hearing the news James Watson had died, a STAT reporter said in our Slack, "I wish I could read what Sharon would have written." Incredible news: Sharon in fact did pre-write a Watson obit. And it is masterful and excoriating. 🧪🧬🧫

What Rosalind Franklin truly contributed to the discovery of DNA’s structure. A really informative article, perfect for a weekend coffee read. www.nature.com/articles/d41...

🚨 A fantastic opportunity to join HIRI to start your research group on RNA Biology 👇 www.nature.com/naturecareer...

If Linux (for OS) is any model, OpenFold3 wants to become the standard for structural biology in academia & industry alike. Ambitious—but necessary. #OpenSource https://www.maffulli.net/2025/10/30/openfold3-open-source-replacement-alphafold/ #ai

Excited to launch an openRxiv partnership with the scientist-run AI review service qed (@qedscience.bsky.social), the brainchild of @odedrechavi.bsky.social 1/n openrxiv.org/enabling-rev...

Great collaboration with @guo-lab.bsky.social to determine an in situ architectural model of the Tad pilus machine. Be on the lookout soon for a preprint on the same topic by Grant Jensen and @viollierpat.bsky.social. #microsky

🚨New preprint out! We present a foundational genomic resource of human gut microbiome viruses. It delivers high-quality, deeply curated data spanning taxonomy, predicted hosts, structures, and functions, providing a reference for gut virome research. (1/8) www.biorxiv.org/content/10.1...

Generative AI antibody design takes a big turn 1️⃣ Atomically accurate de novo design of antibodies with RFdiffusion www.nature.com/articles/s41... 2️⃣Generation of antigen-specific paired-chain antibodies using large language models www.cell.com/cell/fulltex...

New structures of the bacterial Tol complex! www.nature.com/articles/s41...

In situ Architecture of the Tad Pilus Machine in Caulobacter crescentus https://www.biorxiv.org/content/10.1101/2025.11.05.686773v1

Please RT. Post-doc opportunity alert! 💥 closing 10th December.. Come join our team (www.thelowlab.org) at Imperial, London, working on the structure and mechanism of bacterial secretion systems. For more details and to apply please see www.imperial.ac.uk/jobs/search-...

📢 Postdoc position: Cell Biology of Cyanobacteria in my group, as part of the Excellence Cluster "Microbes for Climate" (M4C) in Marburg, Germany. More information at shorturl.at/wNnDT (see Project 2) 🔗Apply at shorturl.at/VsEDl 📅Deadline: Nov 16, 2025 Please repost. #Postdoc

Exciting #postdoc opportunity in T. Gensollen's group! How early-life interactions between the immune system and microbiota shape lifelong immune imprinting and disease risk Learn more: shorturl.at/F8hqE Deadline: January 15, 2026 Contact: [email protected] #Immunology #Microbiology #Microbiota #Omics

Exciting #postdoc opportunity in KL Ung's group! Understanding the molecular mechanisms of cell wall remodeling in pathogens Learn more: shorturl.at/gPuFV Deadline: January 15, 2026 Contact: [email protected] #Protein #Biochemistry #StructuralBiology #Biophysics #CryoEM

Excited to share our new preprint on Myxococcus xanthus! We show that two distinct motility motors can propel the same bacterial cell simultaneously, and that this dual propulsion is tunable by environmental calcium. 🧵 1/6 📄 Read it here →https://www.biorxiv.org/content/10.1101/2025.10.29.685086v1

Please RT. Post-doc opportunity alert! 💥 closing 10th December.. Come join our team (www.thelowlab.org) at Imperial, London, working on the structure and mechanism of bacterial secretion systems. For more details and to apply please see www.imperial.ac.uk/jobs/search-...

Lab’s first paper is out!! We show the first structures of #Asgard #chromatin by #cryo-EM 🧬❄️ Asgard histones form closed and open hypernucleosomes. Closed are conserved across #Archaea, while open resemble eukaryotic H3–H4 octasomes and are Asgard-specific. More here: www.cell.com/molecular-ce...

2025 Lasker~Koshland Special Achievement Award in Medical Science winner Dr Lucy Shapiro discusses her discovery of how bacteria coordinate their genetic logic to generate distinct daughter cells. ja.ma/47ajuLj

First time posting on Bluesky! 🥳 We discovered a new pilus family in cyanobacteria. The pilin has a novel protein fold that forms a super-tight double-layer tube. Similar gene clusters exist in a few cyanobacterial orders. A great collaboration with John and others! www.nature.com/articles/s41...

Biochemical Society's Membrane Protein Conference 7–9 April 2026 Birmingham, UK | Leonardo Royal Hotel - Abstracts welcome for talks & posters - Bursaries available! - Register & submit here: www.eventsforce.net/biochemsoc/f... #MembraneProteins #CallForAbstracts @biochemsoc.bsky.social

How do microbes survive the most extreme environments on Earth and what does that tell us about life beyond our planet? #FEMSMicrobes is welcoming papers on the microbiology of extreme environments and their links to astrobiology. 🦠 🌌 Submit before 31st December 2025: buff.ly/frV0k6l

How can we see the cells that make up a living organism? Membrane-localising tags can drive fluorescent proteins to the cell's outer membrane, making their outlines visible. But the tags don't work well in all organisms. How do you find one for your species of interest? 🧵 Check our latest preprint

Vous êtes étudiant(e) en informatique, ingénierie ou mathématiques dans une université ou une grande école ? La biologie et le fonctionnement du vivant vous intéressent ? Envie d'élargir vos horizons ? Ce stage pourrait vous convenir. www.ebi.ac.uk/about/jobs/i...

PhD project available in my lab. Email me with CV if interested www.findaphd.com/phds/project... #microsky #bioimaging

flagellophiles take note 👇 #MicroSky

🦠🔬🤖🧑‍💻 #mAIcrobe is out! With @pinholab.bsky.social's lab, we launched an open-source framework for high-throughput bacterial image analysis. By rockstars A. Brito & B. Saraiva et al, making #DeepLearning for phenotyping accessible! Easy to use, plus model training 📜 www.biorxiv.org/content/10.1...

mAIcrobe: an open-source framework for high-throughput bacterial image analysis https://www.biorxiv.org/content/10.1101/2025.10.21.683709v1

🚨 We’re hiring! 🚨 @bruzos.bsky.social lab is seeking a highly motivated #PostDoc & a #PhD student to investigate the marine transmissible cancers. 🧬🌊 #sciencejobs #jobalert #researchjob #cancer #marinescience #symbiosis #bioinformatics #MaxPlanck

Hello! The Jacobs-Wagner lab is finally on Bluesky. We’re excited to celebrate science (and scientists!), share our research, and interact with the community. We look forward to connecting with friends and colleagues across the world.

OUT NOW: Inducible transposon mutagenesis identifies bacterial fitness determinants during infection in mice #microsky 🧪 www.nature.com/articles/s41...

New biology: stink bugs inoculate their eggs with a fungus that protects them from parasitoids www.sciencemagazinedigital.org/sciencemagaz...

We’re excited to announce the incredible speaker line-up for the Prokaryotic Cell Biology Conference! Join the leading researchers as they explore the latest advances in Nanoimaging, Cell Growth and Cellular Structures. Join our speakers & register today! ➡️https://bit.ly/47rtkbw #ProkaryoticCellBio

We are happy to share our latest preprint: www.biorxiv.org/content/10.1... A great collaboration with Waldemar Vollmer’s group, along with our fantastic proteomics and metabolomics facilities. @synmikro.bsky.social

🚨Our paper is out! 🥳 Hijacking a bacterial ABC transporter for efficient genetic code expansion. Many congrats to everyone involved - a multi-year effort led by @taruniype.bsky.social @maxfottner.bsky.social www.nature.com/articles/s41... it all started years ago with a failed experiment 🧵👇 1/9

🤩 #ScienceJobs‼️ We look for a 🧑‍🔬 #PostDoc & 🎓 #PhD-student to investigate marine transmissible cancers.🦪 Apply if ur into #cancer #evolution, #microbiome, #marine #bivalves & #computational approaches.🌊🦠🔬 More on mpi-bremen.de #Education & #Career #Jobs #JobAlert #WomeninSTEM #marinescience #Job

BIG ANNOUNCEMENT📣: I haven’t been this excited to be part of something new in 15 years… Thrilled to reveal the passion project I’ve been working on for the past year and a half!🙀🥳 (thread 👇)

Epitranscriptomic control of stress adaptations in Escherichia coli https://www.biorxiv.org/content/10.1101/2025.10.14.682255v1

Ribosome hibernation in archea #microsky #ribosome 💫 www.biorxiv.org/content/10.1...

MCDB Assistant Professor Faculty Search. Please Repost! Applications Due Oct 15th (TOMORROW!) We welcome applications from all areas of physiology and neuroscience - spanning molecular, cellular, systems, and organismal levels. More information can be found HERE: lsa.umich.edu/mcdb/news-ev...

Excited to share our preprint led by Carlos Voogdt et al We developed new genetic tools & genome-wide libraries for species of the Bacteroidales order; constructed saturated barcoded transposon libraries in key representatives of three genera. www.biorxiv.org/content/10.1...

Our collaborative work with W Im lab is now published as V1 in @elife.bsky.social alongside with reviewers comments. We will update this version to answer to reviewers comment but we believe that this version is already a good start to understand mycomembrane structure! doi.org/10.7554/eLif...

Extracellular ATP is an environmental cue in bacteria @cp-cellreports.bsky.social www.cell.com/cell-reports...