#NewResearch While oral bacteria rarely colonize the healthy gut, they dominate the gut microbiome of patients with chronic liver disease. Here a bacterial gene encoded by microbial translocators is linked to gut barrier disruption and fibrosis #MicroSky 🦠 www.nature.com/articles/s41...

#microsky #synbiosky www.science.org/doi/10.1126/...

#microsky #synbiosky www.nature.com/articles/s41...

nature.com/articles/s41564-025-02207-0 We found one of these pseudo-lysogenic phages, also for E. coli, named SW1, that is T1-related, provides a benefit to kin that carry it, and depends on cryptic prophage protein YfdM: doi 10.1016/j.celrep.2019.03.070 (Cell Reports 2019).

#microsky academic.oup.com/ismej/advanc...

#microsky #phagesky #phage defence www.nature.com/articles/s41...

#microsky #phagesky #phage www.nature.com/articles/s41...

#microsky #phagesky #phage www.nature.com/articles/s41...

EMBO Workshop 24 – 27 April 2026 | Taipei, Taiwan Evolving together: from genomics to biological interactions meetings.embo.org/event/26-bio... @chuanku.bsky.social

Society Event Grant: Eligible members can apply for the to attend the 2026 Annual Conference in Belfast, offering up to £350 for UK attendees and £650 for international participants. Apply by midnight GMT, January 2, 2026. 🔗Link here: microb.io/AC26Grant #Microbio26 #Microbiology #MiM26

(OK, I know this is not how I'd do it from the start, but I'm not doing it from the start) Anyone know of a pipeline that uses nanopore reads to call SNPs in a bacterial genome. Kind of like breseq but nanopore (guessing there's way to do this with minmap etc... looking for something benchmarked)

Interesting new paper on Enterococcus lactis (the species formerly known as Clade B E. faecium) 'The Mannose Phosphotransferase System in Enterococcus lactis Is Essential for Gastrointestinal Colonization' onlinelibrary.wiley.com/doi/abs/10.1...

#microsky Always exciting to read about an ABC transporter which uses separate SBPs to capture and transport related yet different substrates. Many such systems are unexplored, but so intriguing. Transporters matter!! journals.asm.org/doi/10.1128/...

#microsky #phagesky Metagenomics suggests temperate #phages contribute auxiliary metabolic genes to small genome bacteria journals.asm.org/doi/10.1128/...

#microsky #phagesky The 3rd (? Lost track!) manuscript on a CRISPR/anti-CRISPR -based transposon tool to study gene essentiality in #phages www.biorxiv.org/content/10.6...

Evolution of rhizobial siderophore utilization via accessory xeno-siderophore receptors and flexible intake machinery for self-produced siderophores academic.oup.com/ismej/advanc...

replicationists & recombinatics take note 👇 cells deal with transcription-replication collisions (TRCs) much more professionally and efficiently than the best bridge engineers. OK, they've had more time to practice... thx, zeynep for pointing this out 🙏 #MicroSky

#microsky #phagesky #phage #synbiosky www.nature.com/articles/s41...

Building synthetic chromosomes one yeast at a time: insights from Sc2.0 - @arccoesb.bsky.social go.nature.com/48Fqxwi

#microsky #phagesky Expression of anti #phage systems in E. coli www.biorxiv.org/content/10.6...

#microsky #microbiomesky The #microbiome of living trees! How cool! www.nature.com/articles/s41...

#microsky #phagesky Gut #phage biobank www.nature.com/articles/s41...

#microsky #microbiomesky #microbiome A probiotic Klebsiella www.nature.com/articles/s41...

#microsky #MGEs journals.plos.org/plosbiology/...

#microsky #phagesky #phage www.tandfonline.com/doi/full/10....

#phage #phagesky

#microsky #microbiomesky www.biorxiv.org/content/10.6...

Check out the original paper (not by us; we just wrote the "journal club") which describes what they did! Also, in a great bit of timing, the authors just published this cool paper in Nature Communications on how these endosymbioses evolve: www.nature.com/articles/s41...

#microsky www.nature.com/articles/s41...

#microsky #phagesky More anti #phage systems in E. coli www.biorxiv.org/content/10.6...

Excited to share new work from @cultivarium.bsky.social on genetic tools (plasmids, inducible promoters, transposases, + more) for Sporosarcina pasteurii. S. pasteurii is used commercially for biocement, controlling road dust, and stabilizing soils, but had no prior published genetics:

New preprint! We explore how gutless marine worms and their bacterial symbionts use organosulfur compounds like DMSP and DMS - key molecules in marine sulfur cycling. Our results show that these compounds support carbon and energy metabolism in the Olavius algarvensis symbiosis.

#microsky #phagesky #phage defence The different roles of the two glucosyltransferases of phage T4 in overcoming antiphage functions www.biorxiv.org/content/10.6...

KlebPhaCol: a community-driven resource for Klebsiella research identified a novel phage family #phage #phagesky Amazing effort by @fnobrega.bsky.social lab academic.oup.com/nar/article/...

#microsky #phagesky Myco #phage holins www.biorxiv.org/content/10.6...

#microsky 😳 www.cell.com/cell-host-mi...

Thrilled to see our Kiwa story out today! A membrane-associated supercomplex that senses infection and blocks replication and transcription. www.cell.com/cell/fulltex... Huge congratulations to Yi and Zhiying for bringing it home, to Thomas for starting us off, and to all the collaborators.

#microsky #phagesky #phge defence Preprint from the @soreklab.bsky.social reporting a plethora of novel TIR-based immune signalling systems www.biorxiv.org/content/10.6...

#microsky #phagesky A DNA-mimicking protein antagonises #phage SPbeta’s repressor and connects SOS response to the control of lysis-lysogeny www.biorxiv.org/content/10.1...

#microsky #phagesky #phage defence www.nature.com/articles/s41...

#microsky Environmental Bacteroidota FTW! Can’t wait to read this through. www.biorxiv.org/content/10.6...

An efficient electrotransformation method for three Bacillus species -in Applied Microbiology and Biotechnology link.springer.com/article/10.1...

#microsky #phagesky Small RNA regulates #phage life cycle www.biorxiv.org/content/10.6...

#microsky #phagesky #phage defence www.nature.com/articles/s41...

#microsky #phagesky #phage receptor identification via TraDIS www.biorxiv.org/content/10.1...

Enrichment of root-associated Streptomyces strains in response to drought is driven by diverse functional traits and does not predict beneficial effects on plant growth -in @plosbiology.org from Devin Coleman-Derr journals.plos.org/plosbiology/...

#microsky #phagesky Structural insights into non-tailed Vibrio #phages www.biorxiv.org/content/10.1...

Predicting homodimers using AplhaFold www.biorxiv.org/content/10.1...

Explicit description of viral capsid subunit shapes by unfolding dihedrons by Ryuya Toyooka et al. www.nature.com/articles/s42...