An interesting observation we made in the lab before I left : membrane fluidity in B. Subtilis (and other Gram+) has two operating regimes in response to a change in temperature: constant between 28°C, linearly increasing above. We thought it would be constant! doi.org/10.64898/202...

I think about this post every day 🧪

One of my favorites.

Have we started the science shitposting yet

it's the 10 year anniversary of a very important study

If your test for ground-breaking discoveries can’t detect the discovery of RNAi, or of CRISPR-Cas9, or the cryoEM resolution revolution or Alphafold2, maybe it’s not a very good test. www.nature.com/articles/d41...

Retweeting this because I thought it was staph at first, and yet it isn't

Happy Saint Patrick!🍀 Meet Saccharomyces cerevisiae—the yeast behind beer!🦠It ferments sugars into alcohol & CO₂ in an oxygen-free environment. At Bordeaux Imaging Center, Isabelle Svahn captured it up close using scanning electron microscopy!🔬 👉france-bioimaging.org/node/bordeaux/

"Teaching of genetics tends to begin with Mendelian traits, presumably because they are deemed easier to understand. This introduces misperceptions about genetic determinism, encouraging linear perspectives on genotype-phenotype relations." A call to embrace complexity by @philipcball.bsky.social.🧪

Worst. Episode. EVER.

New paper out 🎇 It has been 13 years since @owenlabuob.bsky.social and co. published a stellar protocol on how to measure membrane order with smart probes! Since then, there has been new dyes, imaging modes and biology! We wrote a protocol for Nature Protocols: www.nature.com/articles/s41...

The Indigenous People of North America have decided to go back to calling the Gulf of Mexico, “Chalchiuhtlicueyecatl”. It is what the Nahuatl People originally called it as it is the domain of the goddess Chalchiuhtlicue, who is assoc w/water bodies, including the Gulf of Mexico.

#BPS2025 is approaching! ✨🔬🧪 I will be presenting a poster on some TPE metabolic imaging and on a little bit of Phasor FLIM analysis. All recent and unpublished data. Sun Feb 16th - B548 Find me if you are there and interested and want to chat about NADH, FPs, FLIM, or FCS (always up for that).

#Cellpose 3 paper now out. Not all images are perfect. Restore your images with Cellpose3 to get better segmentations, w/ @marius10p.bsky.social www.nature.com/articles/s41...

After a long journey, Segment Anything for Microscopy is now published in Nature Methods! We significantly improve SAM for interactive and automatic segmentation in light and electron microscopy and build a user-friendly tool. www.nature.com/articles/s41...

I don't want a video explaining how to do the thing. I want step-by-step instructions in a plain text document, on a single page, ideally that I can see all of without scrolling while using a reasonably big font.

This looks like a terrific opportunity for anyone who wants to push the best microscopes to their limits!

'Barnett Rosenberg wasnt trying to cure cancer. He wasnt working on cancer. He wasnt working on any disease-related problem. He wasnt even working with human cells. All he was trying to do was to test a hypothesis about what would happen when dividing bacteria were placed in a strong electric field'

Trying to find an old classic paper that was discussing how in science changes of scale induce a change of the rules, e.g explaining that chemistry is not applied physics, biology is not applied chemistry etc. Does it ring a bell with anyone ?

A question for membrane folks: should I expect a change of 3-5% percent in unsaturated fatty acids affect membrane viscosity? It is typically what people measure in cold shocks in bacteria but I find strange that such a small change would have an important effect

I'm a big fan of super plots, advocating it to everyone in the lab !

Any more FFS/FCS Folks on bluesky? Where are you? Time to correlate. Please let me know who is on here and needs to be added. go.bsky.app/4BbiZyW

Allez le lire, c'est long mais très bien, notamment sur la puissance des images dans leur polysémie assumée et qu'on ne cherche pas à encadrer, sur la puissance évocatrice de la ville, et sur le "sens" de l'histoire (vers l'avant, c'est tout ce qu'il en dit). legrandcontinent.eu/fr/2024/07/3...

Salut mes wokistes sûrs, On prend 2 secondes pour voter non juste pour le plaisir de faire chier Bolloré.

2010 was quite a year

Post a movie from the year you turned 18

I am excited to announce that the Journal of Cell Science will have a special issue on imaging cell architecture and dynamics, guest-edited by myself and Lucy Collinson. Consider this issue to publish your work. Find out more: journals.biologists.com/jcs/pages/im...