Cytosine methylation contributes to the fitness of Caulobacter cells naturally expressing a Vsr-like protein: iScience www.cell.com/iscience/ful... 🦠

🦠💫 RNA modifications and stress

⛸️🧬 February RNA Modifications Newsletter From CRISPR-triggered tRNA tail cleavage to temperature-responsive rRNA modifications, ribosome QC, and pathway-specific rRNA modification during biogenesis. #RNAmods #Epitranscriptomics #Ribosome #Translation #tRNA #rRNA

🦠 #rnasky #rnabiology

🦠

accumulation of the 50S subunit in delta-tlyA with cold sensitive phenotype and resistance to aminoglycosides 🦠 #RNAmodifications #RNAbiology #rnasky

Signature codon usage patterns define functional gene families, this is in yeast and could be also very informative for bacteria and link with tRNA modifs #rnasky #codonusage #rnabiology #rnamodifications

trans-Translation inhibitors that kill M. tuberculosis and pathogenic Non-tuberculous Mycobacteria have a dual mechanism of action www.biorxiv.org/content/10.6...

Structure of the 30S translation initiation complex coupled to paused RNA polymerase and its potential for riboregulation #rnasky 🦠

Probing the epitranscriptome and RNA damage with nanopore direct RNA sequencing #tnasky

'This video is the culmination of several yrs attempting to: (1) Figure out best practices for modeling ptn-ptn interactions; (2) Understand the outputs of programs like AlphaFold & adjacent software including quantitative metrics;(3) Communicate my thoughts to unwitting victims through workshops'

A to I RNA editing at the replication fork #RNAsky #RNAbiology

DNA modif and phages 🦠

#RNAsky #RNAbiology #ribosome 🦠

Help without a comic about your research for the greater good! #microsky #science #virosky #ecoevo

"under low amino acid availability, co-cultures of leucine and phenylalanine auxotrophs display greater tolerance to chloramphenicol than monocultures"=> community level tolerance 🦠

Role of RimM ribosome maturation factor in recovery after protein synthesis arrest 🦠 #ribosome #rnasky #rnabiology

Ribosome profiling reveals distinct translational programs underlying Arabidopsis seed dormancy and germination https://www.biorxiv.org/content/10.64898/2026.01.08.696037v1

#ResultatScientifique🔎| Quand Candida albicans réduit ses ribosomes, ses cellules deviennent plus fluides, ce qui l’aide à changer de forme et à mieux infecter l’organisme 🍄 ✍️ Robert Arkowitz 📕 @natmicrobiol.nature.com | buff.ly/zPSLael

Crispr immunity by cutting RNA and not DNA 🦠

Canada Research Chairs www.canada.ca/en/impact-pl...: $1M/year for 8 years, plus up to $6M in CFI infrastructure support. Looking for leading researchers abroad interested in AMR research, antibiotic discovery (Pandemicstopai.ca), phages. Email short vision + CV. Tight deadlines: March 10 & June 15

Proximity-specific ribosome profiling #ribosome #rnabiology in mitochondria www.cell.com/cell/fulltex...

#AMR 🦠

Stress dependent rRNA modifs 🦠💫 #rnasky #rnabiology

🧬❄️ RNA Modifications Newsletter - Jan 2026 is out! RNA mods, ribosome remodeling, codon effects, nanopore detection, translation under stress - winter edition ❄️🧫From hypoxia-driven rRNA methylation to tRNA-linked virulence and ribosome structure. #RNAsky #RNAbiology #Ribosome #microsky

2025 in a nutshell 🚀 6 papers out 👇, 1 press release 🔖(www.pasteur.fr/en/press-are...) from @pasteur.fr, a move to EGM - IBPC 🚚, and the launch of RNA Modif Newsletter 🦠 Also: new faces 😊, farewells 🥲, great collaborations 💫, and we even saved the world from a meteorite.🤩 More coming in 2026 ✨🤞

Our latest paper on protein expression and mRNA stability is out! academic.oup.com/nar/article/... Check out how to increase your protein output with a simple trick. Congratulations to first author @Anna Lipońska, it was a great collaboration with the Aalberts group. #RNAsky #ribosome #EGM

1/ Our new preprint is out on biorxiv on how antibiotics bind to bacterial 30S subunits, please repost. #ribosome #antibiotics #microsky #rnasky doi.org/10.64898/202...

Defining bottlenecks and physiological impact of an orthogonal translation initiation system doi.org/10.64898/202...

Our recent paper in npj Antimicrobials and Resistance is a great example of scientific serendipity: after staring at thousands of bacterial growth curves over many studies, we started wondering whether the curve shapes themselves carry mechanistic information 1/9 🦠🧪 www.nature.com/articles/s44...

AI based framework for RNA modif detection using nanopore #RNAbiology

Thrilled to share that my first-author paper is now published in Nature Communications! 🎉 Huge thanks to my PI, Dr. Drew Bridges (@bridgesbio.bsky.social), my collaborators, and all the incredible lab members for their support throughout this project www.nature.com/articles/s41...

😮 #microsky

"base composition in the first six codons modulates local mRNA folding energy and single-strandedness to control the balance between productive translation initiation versus degradation of mRNAs" 🦠 #RNABiology #RNAsky Congrats to Greg Boel team #EGM academic.oup.com/nar/article/...

Stress-induced toxic genomic R-loops support biofilm extracellular matrix formation 🦠 #Rloops #RNAbiology www.nature.com/articles/s41...

Our new paper on DusB’s role in redox metabolism in V. cholerae is now out in @narjournal.bsky.social linking tRNAmodif enzymes and metabolic adaptation. Beyond RNA modification: a tRNA-modifying enzyme shaping oxidative stress resilience and metabolism in V. cholerae #rnasky #rnabiology 😊🦠💫

My talk from the latest RNA Collaborative Seminar Series is now available on YouTube. The second talk in the session was given by Rachel Braun (Sara Cherry’s lab) on TTP and its role in regulating antiviral immunity. youtu.be/2Aj-xbi3dPI #RNAsky #RNAbiology

We've come full circle! I began my postdoctoral career by identifying the peptidyl deformylase gene. Today, we show that half of bacterial species harbor multiple PDF genes (up to 7, for always a single Met-tRNA transformylase), and while the role of these PDFs ... academic.oup.com/mbe/article/...

After D2449 by rdsA, now new methylations in E.coli rRNA under stress 💫

Implications of Codon Usage, tRNA Gene Redundancy and tRNA Gene Clustering in Experimental Models of Mistranslation doi.org/10.1016/j.jm...

❄️ December RNA Modifications Newsletter is out! ❄️ rnamodifupdates.substack.com/p/rna-modifi... ❄️🔥RNA modifs = winter’s hottest adaptation toolkit. 🦠 #Ribosome #RNAbiology

Impact of Small RNA Sponges on Regulatory RNA Networks in Bacteria #microsky www.annualreviews.org/content/jour...

👍 #MicroSky #RNASky 👇

Using "in extracto cryo-EM", we visualize ribosomes in mammalian lysates, including RRL. "Hibernating" ribosomes carry an extended set of proteins that protect functional centers. These include elongation factor eEF2, LARP1 implicated in mTOR signaling, eIF5A etc. www.biorxiv.org/content/10.1...

Unraveling the prevalence and multifaceted roles of accessory peptide deformylases in bacterial adaptation and resistance url: academic.oup.com/mbe/article/...