AI: a metaphor

Like, actively deleted the Tweets. Not just deactivated my account. If you are still on that platform, X is using your information to feed LLMs for its own benefit and to generate mis- and disinformation in your name with your content.

When I quit Twitter/X, I made sure to delete 18 years of Tweets, because I knew this was coming. If you’re still on that platform, you are enabling sooooo much disinformation.

A super detailed protocol + video on Cryo-ExM - Cryo-Expansion Microscopy, led by the labs of our former postdocs @marinelap.bsky.social & @ebertiaux.bsky.social. Clear, practical, and very useful for anyone doing nanoscale imaging 🚀 app.jove.com/t/68595/expa...

You've been kidnapped. The characters from the last TV show you watched are trying to rescue you. Who's coming to save you?

Structure and organization of AMPA receptor-TARP complexes in the mammalian cerebellum | Science www.science.org/doi/10.1126/...

Happy to share the last work of @jmartinkus.bsky.social, led by @dukasju.bsky.social Immunity arrays associated with Rhs and CDI toxins and linked to a novel genetic element (XPC cassette) confer protection against competitors. @currentbiology.bsky.social Kudos !! www.cell.com/current-biol...

Many thanks to my PIs, collaborators, and team! I'm excited to share this paper from my PhD work!

So structural biology is not dead after all 😋 Not a big surprise The title of this article is exactly in line with what I think. Same applies to LLMs for scientific writing.

🔬 Just out in @NatureComms! Using cryo-CLEM and cryo-ET, we reveal the unique ultrastructure of dopaminergic varicosities in the striatum. Amazing collaboration with @davip-bdx.bsky.social and Etienne Herzog @iins-bordeaux.bsky.social Congratulations to Paul and Robin for this fantastic work! 🎉

a genius! Happy birthday !

🤯 indeed !!

"there's a new serif in town"

Not Gaulliste anymore on dirait !

#LivingArchitectures We put cells and cytoskeleton filaments on the architecture of the musée d'Orsay. www.musee-orsay.fr/fr/agenda/ev... Scientists of the #CytoMorphoLab adapted their protocols to illustrate the questions that keep them awake at night. -> Two shows on the 24th and 25th of January.

Quick survey for fellow scientists abroad: Does your institution block or restrict the use of commercial AI assistants (ChatGPT, Claude, etc.)?

Bientôt plus le droit d'utiliser ChatGPT, Claude, et al. au CNRS

To celebrate my book of simple 'Bluesky Recipes' and survival tips for 'Difficult Days' winning the Gourmand Award for 'Food & Mental Health', I'm basically giving it away. UK www.amazon.co.uk/dp/B0DWLYCR96 (99p) USA www.amazon.com/dp/B0DWLYCR96 ($1.99) #Cookbook #FoodSky #BookSky #Recipes #Foodie

Nice move @cnrs.fr From 2026, no more Web of Science. But is the community truly ready for qualitative evaluation? Hiring, promotions, grants… we’ve all been shaped by the metrics we grew up with. Changing the mindset is the real challenge and will take time.

The title of the conference J’adore !

Si je peux me permettre, les scientifiques ne "trouvent" pas. Ils découvrent. "Trouver" suppose qu'on savait ce qu'on cherchait. Or nous progressons dans l'inconnu, souvent guidés par l'inattendu.

Is LLPS the cell biologists' equivalent of the FSC discussions in cryo-EM? Recent threads on here make me think that.

L’émission coup2point sur les i de Kathya DE Brinon où nous témoignons de la situation de nos petits-enfants. Liked et repostez ! On continue le combat pour les récupérer et les sauver youtu.be/Gh6x5Avf0-I #placements #protectiondelenfance

Congrats to @chgjohnston.bsky.social , Andreani, Radicella et al.! Elegant PNAS paper on the ComEC/ComFA/ComFC complex in bacterial transformation. AF3 predictions validated by clever mutagenesis. We tried for years to solve this by cryo-EM/crystallography - never succeeded.

Are we really surprised ?

Very happy to share our work on lipopolysaccharide assembly by the Lpt complex, published today in @natcomms.nature.com Fantastic collaboration with @raffaeleieva.bsky.social l and t @pstansfeld.bsky.social Congrats to all authors, especially Haoxiang, Axel & Violette 🔗 doi.org/10.1038/s414...

How does linguistic bias reinforce privilege in science? #AppEnvMicro Editor in Chief @microgem.bsky.social offers insights and discusses how reviewers can identify it to support a more equitable review process. Read the article: asm.social/2Hp #COPE #PublicationIntegrity

Our latest T7SS study is now out in Science Advances! We solved the cryoEM structure of the T7SSb core unit (T7bCU) composed of YukB, YukC, and YukD from Bacillus subtilis, revealing how these components assemble within the secretion machinery. www.science.org/doi/10.1126/...

Sounds like a good excuse when arriving late to work

Know the difference.

Fixation artifacts will haunt us forever until we get real about them.

Congrats Eloïse !

New online! The type VI secretion system and associated effector proteins

Great review that pinpoints many critical gaps in the field! The PS "paradigm" needs to be tested/confirmed properly in cellulo in native conditions. Not easy.

Fucking magnates, how do they work

NMR spectroscopists according to the President of the USA (and let's be honest, according to everyone else) 😁

"nobody knows what magnets are" DJT

Oh! Here's a combined PDF of all three papers: www.mskcc.org/teaser/1953-...

I am seeing a lot of posts about Rosalind Franklin that themselves ignore her publication record on DNA! In fact Franklin and Gosling's paper, including the famous Photograph #51, was published, along with Wilkins's paper, back-to-back with the Watson and Crick paper in Nature in 1953.

I learned a lot from reading the posts over the last 2 days. I was struck by how much we are influenced by scientific mythology, some of it rooted in what we learned as far back as high school.

Just read the full letter. Wow ! « But the point of science is what is discovered, not how it was discovered or by whom. It is the results which need to be brought home to the public. » F. Crick.

I recommend reading this thread from F. Crick’s granddaughter. Apparently even the scene at the Eagle pub, where we all went as scientific pilgrims, is not true? Just mythology

You know what? I did not read “The Double Helix.” I was converted to molecular biology by the books from Monod and Jacob, real decent and courageous men in addition to being exceptional scientists. For me, one cannot go without the other!!

Some still praise James Watson despite his racism. Same with colleagues who won’t condemn Elon Musk’s politics, hiding behind “scientists shouldn’t mix science and politics.”

X Thinking about Rosalind (and Maurice)

Not sure to miss him…

Many thanks to the folks at the San Diego Supercomputer Center for highlighting our project!