Don't ignore the "contaminants" on your grids ! We noticed this filament while solving the S. sanguinis T4P structure during my PhD. It turned out to be an incredible eDNA-protease assembly: literally a suspension bridge of proteins & DNA ! 🌉 Happy to finally share this story. #CryoEM #Microbiology

Exciting times for our lab- recent developments in cryoET tools and workflows now allow us apply these to study microbes in the host context. #teamtomo www.sciencedirect.com/science/arti...

Happy to share our new bioRxiv preprint: “To Kill or not to Kill: A Conserved Trans-Intoxication Protection Factor Blocks X-T4SS-Mediated Fratricide through Interaction with VirB5” www.biorxiv.org/content/10.6...

New Title Alert: AF3Complex- is a model equipped with the same improvements as AF2Complex, along with a novel method for excluding ligands, built on AlphaFold 3. Learn more here: buff.ly/GPEgFSF #SBGrid #Software #Predictions

Still possible to register for the 14th Young Scientists' Symposium! 📅 4-5 June 2026 @iecb.bsky.social @univbordeaux.bsky.social Fantastic lineup of keynote speakers. @marionjasnin.bsky.social @amjjbonvin.bsky.social @olallalab.bsky.social

📢 Les inscriptions au Young Scientists' Symposium 2026 sont désormais ouvertes ! Pensez à vous inscrire et à diffuser l’information autour de vous 👇 Inscriptions : bit.ly/3OiYTxG Modèle d'abstract pour les présentations orales et/ou posters : lnkd.in/e2x8KJMG

The new ChimeraX CubeNTube plugin allows erasing parts of maps using cube, cylinder, and custom shapes and has undo. Created by Tamino Cairoli. Available from ChimeraX menu Tools / More Tools....

Since last year, I've been making a RELION GUI that supports viewing, navigating and running jobs in a way completely compatible with the original RELION pipeline. Now it's working nicely for both SPA and tomography! Please try it out - github.com/hanjinliu/hi...

🔬 Just out in @NatureComms! Using cryo-CLEM and cryo-ET, we reveal the unique ultrastructure of dopaminergic varicosities in the striatum. Amazing collaboration with @davip-bdx.bsky.social and Etienne Herzog @iins-bordeaux.bsky.social Congratulations to Paul and Robin for this fantastic work! 🎉

Very happy to share our work on lipopolysaccharide assembly by the Lpt complex, published today in @natcomms.nature.com Fantastic collaboration with @raffaeleieva.bsky.social l and t @pstansfeld.bsky.social Congrats to all authors, especially Haoxiang, Axel & Violette 🔗 doi.org/10.1038/s414...

Our latest T7SS study is now out in Science Advances! We solved the cryoEM structure of the T7SSb core unit (T7bCU) composed of YukB, YukC, and YukD from Bacillus subtilis, revealing how these components assemble within the secretion machinery. www.science.org/doi/10.1126/...

Happy to announce "Technical Innovations Using #SerialEM: A Community Meeting", a new format of hybrid meeting David Mastronarde and I are organizing in April 2026. For more info, a preliminary list of speakers, pre-registration etc. visit www.nexperion.net/semcm2026

“The Website” is here! It can be intimidating getting into analysis of #CryoET data, and software is evolving all the time👩‍💻🚀. @phaips.vd.st & @florentwaltz.bsky.social put our lab’s workflows into an online guide. We hope this helps lower the bar to joining #TeamTomo. Feedback much appreciated! 🧪🧶🧬🔬

1/5: Over the last few months, I have been working on an update for the #FollowRelionGracefully dashboard, which offers improved real-time job previews for #cryoEM #Relion jobs.

🦠🧠 MemBrain update! 🧠🦠 We’ve updated our preprint! It now covers the full MemBrain v2 pipeline for end-to-end membrane analysis in #CryoET: segmentation, particle picking, and spatial statistics. 🔗 Preprint: doi.org/10.1101/2024... 🔗 Code: github.com/CellArchLab/... 🧵(1/6) #TeamTomo

We're on the cover of @science.org this week. Awesome work by @florentwaltz.bsky.social. #CryoET is reaching crazy resolutions inside cells, and this is just the beginning. Fantastic interpretation of the proton motive force by @verenaresch.bsky.social. Always a pleasure making #SciArt with you!🧪🧶🧬🌾

ChimeraX can be used to find pockets and cavities in protein structures using the Find Cavities tool or kvfinder command. This feature is available in daily builds from 10 March 2025 or later.

AreTomoLive: Automated reconstruction of comprehensively-corrected and denoised cryo-electron tomograms in real-time and at high throughput www.biorxiv.org/content/10.1101/2025.03.11.642690v1 #cryoem

Stand up for science in Bordeaux

Cryo-iCLEM: Cryo correlative light and electron microscopy with immersion objectives pubmed.ncbi.nlm.nih.gov/39971020/ #cryoem

🔬Our @haselbachlab.bsky.social with Pavol Harar have developed ‘FakET’! The new method creates ‘fake’ electron microscopy images to train AI, reducing manual work in particle identification. Read the full story: www.imp.ac.at/news/article... @viennabiocenter.bsky.social #AI #cryoem #microscopy

Are you using @napari.org or want to learn more? I've curated a list of videos about napari and its uses on YouTube. If I missed a video, please let me know. www.youtube.com/playlist?lis...

After a long journey, Segment Anything for Microscopy is now published in Nature Methods! We significantly improve SAM for interactive and automatic segmentation in light and electron microscopy and build a user-friendly tool. www.nature.com/articles/s41...

CryoCrane, a visualization tool for cryo-EM screening data, aims to provide an intuitive way to visualize micrographs and to speed up data analysis. #CryoEM #SampleOptimization #GridScreening doi.org/10.1107/S205...

Very happy to share our last preprint where we investigated the vesicular organization of dopamine hub synapses with cryo-CLEM. It is a brain structure that emerges as an important regulator of striatal activity. Many thanks to David Perrais, Etienne Herzog and the lab of @fronzeslab.bsky.social !

@stevestuwill.bsky.social you posted on 𝕏 on Dec 5, 2020 this stunning video - why not repeat on 🔵bsky ? (sorry, I did)... "Time-lapse footage of a vampire amoeba: a microscopic organism that feeds on algal cells by breaking through their cell walls and sucking out their insides." #ProtistsOnSky

Hey #teamtomo, if you often find yourself using the excellent membrain-seg from @lorenzlamm.bsky.social et al., you might find my napari plugin "napari-segselect" useful. Let's say your tomogram contains the edges of two bacterial cells, each with a membrane and cell wall:

Answering the call of @haesleinhuepf.bsky.social, Christian Tischer, Pete Bankhead, @kbias.bsky.social @bethcimini.bsky.social My Fiji training notes are now FAIR. All online in an open format to download and use for teaching and training. All in Google Doc or PDF formats bit.ly/4hkfEBF

DeepSeek's open AI model is giving scientists worldwide the opportunity to train custom reasoning models designed to solve problems in their disciplines. https://go.nature.com/4azXz07

I am starting to assemble a starter pack with past and current members of our institute @iecb.bsky.social Send me a message if you wish to be included. go.bsky.app/L86XUk1

An #AI model created to design proteins simulates 500 million years of protein evolution in developing a previously unknown bright fluorescent protein. Learn more in a new Science study: https://scim.ag/40l2z3J

We are very pleased to share our latest preprint on the architecture of the membrane complex of the type 7 secretion system involved in bacterial competition in B. subtilis. #CryoEM #microsky

In case you missed our first webinar of 2025, it is now available. Lorenz Lamm from MUDS - Munich School for Data Science presented MemBrainv2- an end-to-end tool for the analysis of membranes in cryo-electron tomography. https://buff.ly/4hutFwf #SBGridwebinars #ScienceMatters

A decade in, expansion microscopy is unlocking insights across biology and medicine https://go.nature.com/4adlNgg

We have an open PhD position to work on bacterial secretion systems. Please RT, write us or apply through the CNRS job portal: t.co/HxX23Od1oa

Non-comprehensive list of projects, hardware, software, and people related to #OpenMicroscopy. List could do with some updates, so please share and suggest additions! github.com/HohlbeinLab/...

🔬 Tired of dropping CryoEM grids during manipulation? Check out my 3D-printed holder! Download the STL file here: www.printables.com/model/900940.... Compatible with glow discharge systems, it makes your workflow smoother and more efficient. 💡 #CryoEM #3DPrinting #OpenScience

You want to build an apparatus for time-resolved cryo-EM? Easy: bio-protocol.org/en/bpdetail?...