Fisk University student Cariuna Ellison's highlight features a paper from Fengbin (Jerry) Wang of University of Alabama at Birmingham that appeared in Emerging Topics in Life Sciences: Electric Bacteria: Biological “Power Cords” Read more here: buff.ly/M2lX8Ct #SBGrid #cryoEM #Bacteria

SBGrid's eLife paper received a citation in January from Dhirendra Simanshu at Frederick National Laboratory for Cancer Research in @nature.com Communications Read more here: buff.ly/YynO1k1 #SBGrid #StayConnected #ScienceMatters

SBGrid's eLife paper received a citation in January from @drennanlab.bsky.social at @mit.edu in @nature.com : A highly dynamic mononuclear non-heme iron enzyme for the two-step isonitrile biosynthesis. Read more here:https://buff.ly/t8tGieS #SBGrid #StayConnected #ScienceMatters

SBGrid's eLife paper received a citation in January from Jean-Philippe Julien at @sickkidsto.bsky.social in @Nature Magazine Communications: A stabilized tandem antigen chimera that elicits potent malaria transmission-reducing activity. Read more here: buff.ly/AnmiV5Y #SBGrid #ScienceMatters

New Member Alert: Martin Schmeing at @mcgill.ca joined SBGrid in January. Welcome!

New Title Alert: ThermoMPNN- is a graph neural network (GNN) designed to predict changes in stability for protein point mutants using transfer learning. Learn more here: buff.ly/cXIXkW8 #SBGrid #SBGridSoftware #StructuralBiology

SBGrid's eLife paper received a citation in January from @awehenkel.bsky.social , Pedro M. Alzari, and Ahmed Haouz from @pasteur.fr in ASM Journals: Mechanistic insights into SteAB regulation of cell wall hydrolase RipA in Mycobacterium tuberculosis. Read more here: buff.ly/tY3MqKF #SBGrid

New Title Alert: Slabify- is a command-line tool designed for the automatic segmentation of lamella slabs in cryo-electron tomography (cryo-ET) volumes. Learn more here: buff.ly/fVsKsOS #SBGrid #SBGridSoftware

New Member Alert: Esther Ortega from @cnb-csic.bsky.social joined SBGrid in January. Welcome!

SBGrid's eLife paper received a citation in January from @heppnerd.bsky.social at @ubuffalo.bsky.social in @acsmedi.bsky.social Letters: Structural Studies of Fourth-Generation EGFR Inhibitors Reveal Insights into Selective T790M and C797S TargetingArticle link copied! More here: buff.ly/6K0CRwv

New Member Alert: Maria Oliva-Blanco from Margarita Salas Center for Biological Research joined SBGrid in January. Welcome!

New Title Alert: MagCalEM- Accurate magnification determination for cryoEM determining the correct magnified pixel size of single-particle cryoEM micrographs is necessary to maximise resolution and enable accurate model building. Learn more here: buff.ly/vuCrtWR #SBGridSoftware #SBGrid

New Member Alert: Fangyu Liu from UT Southwestern Medical Center joined SBGrid in January. Welcome!

New Title Alert: LASErMPNN- is an all-atom ligand-conditioned protein sequence design and sidechain packing model that accounts for the presence of small molecules, including hydrogens. Learn more here: buff.ly/cZcOmpC #SBGridSoftware #SBGrid #StructuralBiology

SBGrid's eLife paper received a citation in January from Eric Girard at IBS Grenoble in @angewandtechemie.bsky.social: Action of Crystallophore and Imaging-Crystallophore Enhances the Production and Imaging of Protein Crystals. Read more here: buff.ly/Cjk6R1c #SBGrid #ScienceMatters #StayConnected

New Title Alert: IsoNet2- a deep-learning software package for simultaneous missing wedge correction, denoising, and CTF correction in cryo-electron tomography reconstructions using a deep neural network trained on information from the original tomogram(s). Learn more here: buff.ly/2ZlZInD #SBGrid

New Member Alert: In January, @joanafb.bsky.social from @biologiaub.bsky.social joined SBGrid. Welcome!

New Title Alert: ImmuneBuilder- is a high-performance deep learning framework developed by the Oxford Protein Informatics Group (OPIG) specifically for predicting the 3D structures of immune receptor proteins. Learn more here: buff.ly/wCaRFLp #SBGrid #SBGridSoftware #StructuralBiology

New Member Alert: In January, @awehenkel.bsky.social , along with the Image Analysis Hub, under the direction of @jytinevez.bsky.social at @pasteur.fr joined SBGrid. Welcome!!

Technical Notes: January's software push includes updates to 15 titles -- anvi’o, BioXTAS RAW, ChemEx, CryomaskR, DeepRank-GNN-esm, DSSR, GROMACS, Icecream, IMP, PowerFit, PyEM, RDKit, SRAToolkit, Volume_Seg_Tool, and XDS. More here: buff.ly/4ZaSgEV #SBGridSoftware #Updates

New Member Alert: Daniel Castaño from Biofisika Institute joined SBGrid in January. Welcome!

New Title Alert: Foundry- is a unified framework for protein design that provides tooling and infrastructure for using and training models. Learn more here: buff.ly/2TdjDOE #SBGrid #SBGridSoftware #StructuralBiology

If you missed Alice-Roza Eruera's January webinar on Building CryoET Training Workflows Using the SBGrid Ecosystem, you can now find it on our YouTube channel. Here: buff.ly/CPcy0Nz #SBGrid #Webinars #ScienceMatters

Technical Notes: Personal Installation Credentials Users who currently only have access to the SBGrid software collection through a site installation may benefit from access to the collection on personally managed laptops or desktops in the laboratory or at home. Register here:

SBGrid's eLife paper received a citation in January from @bhartisingal.bsky.social , at @stanford.edu SLAC CryoEM Initiative contributing in @nature.com Chemical Engineering Read more here: buff.ly/a4Wfrej #SBGrid #ScienceMatters

New Title Alert: ConSurf- is a bioinformatics tool designed for estimating the evolutionary conservation of amino and nucleic acid positions in protein, DNA, and RNA molecules. Learn more here: buff.ly/ormnLqE #SBGrid #SBGridSoftware #StructuralBiology

New Member Alert: James Chen from University of California, San Francisco joined SBGrid in January! Welcome.

Join our software webinar on February 10th to hear from Alyssa Travitz of the @omsf.io on @openfree.energy: An Open Source Ecosystem for Calculating Free Energies. Tuesday, February 10, 2026 - 12:00pm ET Register here: buff.ly/N7AYdjp #SBGrid #Webinars #StructuralBiology

New Member Alert: Javid Babak from University of California, San Francisco joined SBGrid in January. Welcome!

Fisk University student Cariuna Ellison's highlight features a JCI Insight publication from the lab of Charles Sanders at @vanderbilt.edu in which the authors describe a small molecule that may change the trajectory of LQTS intervention research. Read more here:

SBGrid's eLife paper received a citation in January from @mclellanlab.bsky.social from @utaustin.bsky.social in @nature.com : Structure and immunogenicity of an engineered soluble prefusion-stabilized EBV gB antigen. Read more here: buff.ly/4nvSiyg #SBGrid #ScienceMatters

New Title Alert: Calc_level_chimeraX- is a ChimeraX plugin to predict and visualize isosurface levels for 3D density maps. Learn more here: buff.ly/8tWjgTF #SBGridSoftware #SBGrid #StructuralBiology

New Title Alert: ThermoMPNN-D- is a Siamese neural network designed to predict stability changes from protein double point mutations. Learn more here: buff.ly/rogxB7G #SBGrid #SBGridSoftware #StructuralBiology

Our January member tale features Jean-Philippe Julien from @sickkidsto.bsky.social in Toronto, who interrogates antibodies in the science of global heath, following their stories to guide interventions against infectious diseases like malaria. Read more here: buff.ly/DVtsSAc #SBGridTales

If you missed Alice-Roza Eruera's January webinar on Building CryoET Training Workflows Using the SBGrid Ecosystem, we will have the video posted to the SBGrid YouTube channel soon. You can subscribe at buff.ly/RTDvlIb to receive alerts when new videos are added. #SBGrid #Webinars #ScienceMatters

SBGrid's eLife paper received a citation in December from @sachsegroup.bsky.social from @fz_juelich in @natcomms.nature.com: Structural organization of p62 filaments and the cellular ultrastructure of calcium-rich p62-enwrapped lipid droplet cargo. Read more here: buff.ly/SLLij5O #SBGrid

SBGrid's eLife paper received a citation in December from Catherine Drennan from @mit.edu in Science Advances: How ATP and dATP reposition class III ribonucleotide reductase cone domains to regulate enzyme activity. Read more here: buff.ly/D3YfAhc #SBGrid #ScienceMatters

New Member Alert: In December, Paul Seidler from @usc.edu joined SBGrid. Welcome!!

SBGrid's eLife paper received a citation in December from David Jeruzalmi atThe City College of New York in @narjournal.bsky.social Read more here: buff.ly/zCdXpjI #SBGrid #ScienceMatters

New Member Alert: Vera Moiseenkova-Bell from @isbupenn.bsky.social joined SBGrid in December!. Welcome!!

New Title Alert: REPIC- REliable PIcking by Consensus (REPIC) is a consensus methodology for harnessing multiple cryogenic-electron microscopy (cryo-EM) particle picking algorithms. Learn more here: buff.ly/cCqyNHx #SBGrid #SBGridSoftware #StructuralBiology

SBGrid's eLife paper received a citation in December from Elizabeth Campbell from @rockefeller.edu in @natmicrobiol.nature.com: Transcription co-inhibition alters drug resistance evolution and enhances Mycobacterium tuberculosis clearance from granulomas. Read more here: buff.ly/6yvUxRw #SBGrid

New Title Alert: cryomaskR- is a desktop application that provides WYSIWYG mask generation for cryo-electron microscopy data analysis. Learn more here: buff.ly/MC0uNqR #SBGrid #SBGridSoftware #StructuralBiology

Our January software webinar will feature Sliz Lab postdoc Alice-Roza Eruera on Building CryoET Training Workflows Using the SBGrid Ecosystem. Be sure to join us on January 13th! Register here: buff.ly/wwNF6Zh #SBGrid #StructuralBiology #Webinars

SBGrid's eLife paper received a citation in November from Rick Page from Miami University Ohio in Biochemical and Biophysical Research Communications: Functional and structural analyses of UbcH5 mutants with enhanced binding to the E3 ubiquitin ligase CHIP. Read more here: buff.ly/y6AVbkb #SBGrid

New Title Alert: meteor- a tool for computing crystallographic difference maps that specializes in robust identification of weak signals from minor populations such as bound ligands or time-resolved experimental changes. Learn more here: buff.ly/bgJYF9N #SBGrid #SBGridSoftware #StructuralBiology

SBGrid's eLife paper received a citation in November from @palencialab.bsky.social from @ugrenoblealpes.bsky.social in @natcomms.nature.com Hierarchical folding-upon-binding of an intrinsically disordered protein. Read more here: buff.ly/EYrkdWw #SBGrid #Stayconnected

Technical Notes: This month's software push includes updates to BioEmu, BoltzGen, ChimeraX, DOCK, Google Cloud SDK, HADDOCK3, NAMD, OpenFold, ORCA, pytom-match-pick, pyTME, SamTOOLS, Schrödinger 2025-3 and 2025-4, and Topaz. More information here: buff.ly/lgtNHCd #SBGrid #SBGridSoftware

SBGrid's eLife paper received a citation in November [email protected] from @harvardmed.bsky.social [email protected] : Structures of human organellar SPFH protein complexes. Read more here: buff.ly/lbuE0ZR #SBGrid #ScienceMatters

New Member Alert: Cesar Santiago from @cnb-csic.bsky.social in Spain joined SBGrid in November. Welcome!