Learn principles of image processing to determine macromolecular structures by #cryoEM: Sign up for EMBO Practical Course on Image processing for cryo-electron microscopy in London, UK, 9–16 September Deadline: 25 April meetings.embo.org/event/25-cry... #EMBOcryoEM #EMBOevents 🧪

A new chapter has begun for two of the world’s most popular preprint platforms, bioRxiv and medRxiv, with the launch of a non-profit organization that will manage them https://go.nature.com/4iCVnHL

another piece, covering our work! Thanks to Laura Tran at the Scientist!! www.the-scientist.com/challenging-...

Excited to share our new preprint "Dynamic nanoscale architecture of synaptic vesicle fusion in mouse hippocampal neurons" www.biorxiv.org/content/10.1... We combine optogenetic stimulation of neurons with in situ cryo-ET to characterize membrane dynamics during synaptic vesicle fusion ❄️🔬⏱️

New preprint from the MemTraS team ! www.biorxiv.org/content/10.1... Great collaboration with @fronzeslab.bsky.social and Vladan Lucic to determine the first cryo electron tomography images of dopamine "synapses" extracted from adult mouse brain.

This study was key to establishing #cryoCLEM and #cryoET in Bordeaux. It is an important milestone. @davidp-bdx.bsky.social, Étienne Herzog and @paulosh.bsky.social took the risk to be the first to use this approach with us. 🙏🙏🙏

Very happy to share our last preprint where we investigated the vesicular organization of dopamine hub synapses with cryo-CLEM. It is a brain structure that emerges as an important regulator of striatal activity. Many thanks to David Perrais, Etienne Herzog and the lab of @fronzeslab.bsky.social !

Cryo-correlative light and electron tomography of dopaminergic axonal varicosities reveals non-synaptic modulation of cortico-striatal synapses https://www.biorxiv.org/content/10.1101/2025.02.07.637058v1