November #ImageOfTheMonth goes to M.Pujol from LPCO lab (UMR 5629). Acquired with Transmission Electron Microscopy, it shows a polystyrene (PS) latex obtained by post-dispersion of a yogurt cup made of PS in water using a surfactant. The resulting particles are highly heterogeneous and large.

‪October #ImageOfTheMonth is from O. Barba-Vila from @iins-bordeaux.bsky.social Slice of the gustatory cortex showing axons from the gustatory thalamus (G), basolateral amygdala (R) and a thick-tufted layer 5 neuron (W), recorded through patch clamp and imaged via biocytin-streptavidin labelling

September #ImageOfTheMonth is from @rkinet.bsky.social from @imn-bordeaux.bsky.social This is a maximum projection of a confocal image of a microglia cell (blue) and its nucleus (red), internalising multiple nanoparticles (yellow), one day after supranigral injection in C57B6-J mouse

August #ImageOfTheMonth is from L.Congiu from @imn-bordeaux.bsky.social. This is a 3D reconstruction of a CD68-positive particles (white) within the cell body of microglia cells (Red) in the mouse cortex. The confocal Z-stack was processed with Imaris software.

It’s good to be back at the BIC! @bic-bordeaux.bsky.social 🔬

July #ImageOfTheMonth is from A.Drouet from @iins-bordeaux.bsky.social. This image represents a neurosphere (150x150 µm) formed from dissociated hippocampal neurons cultured for 14 days under non-adhesive conditions. Yellow shows GFP expressing neurons and nuclei are showed in cyan.

June #ImageOfTheMonth is from L.Boutaleb from @inrae-bfp.bsky.social. They study the impact of heat stress on cell division and DNA replication on the tomato meristem. On this confocal image, EdU staining (magenta) detects replicating DNA and Hoechst labeling (cyan) shows all cell nuclei.

May #ImageOfTheMonth was from C.Mazocco & M.Darricau from @imn-bordeaux.bsky.social. Staining on spinal cord slices reveal TDP43 protein in the nucleus of neurons (Red). Motoneurons and synaptic terminations were stained targetting ChAT (Cyan).

Time to expand your vision! 👀🌱 Our latest work on ExM in plants is out Back-to-back with the Danzl 's lab (@ISTAustria) led by Magali Grison @lbm-bordeaux.bsky.social with @monica-bic.bsky.social and @gmaucort.bsky.social from the @bic-bordeaux.bsky.social . academic.oup.com/plcell/artic...

Finally out!, after a few months of delay, our protocol on ExM in plant roots is now available in The Plant Cell academic.oup.com/plcell/artic... Beautiful images in a great collaboration of the @bic-bordeaux.bsky.social with @emmanuellebayer.bsky.social and Magali Grison @lbm-bordeaux.bsky.social

April #ImageOfTheMonth is from H. Vaïtinadapoulé (BiiO EA 2521). Here is a guttae, a “drop-like deposits” of extracellular matrix components on the surface of the cornea. This image was acquired using scanning electron microscopy with the help of F.Decoeur from the EM unit of the BIC.

March #ImageOfTheMonth goes to M.Bonhivers from MFP lab (UMR 5234). Trypanosoma brucei cell was extracted in detergent, expanded 4.2 fold using U-ExM, labelled for the microtubule cytoskeleton (magenta) and for the Hook Complex (yellow), and images usinf scanning confocal microscopy.

Super-resolution microscopy unravels a dynamic tubular network that is stabilized by pre-existing Golgi and lipids to mature into new Golgi pre-cisternae, @bic-bordeaux.bsky.social, @cnrsbiologie.bsky.social, @cnrsaquitaine.bsky.social, #Lipids, #ExpansionMicroscopy, #PlantScience, #PlantCellBiology

Save the date ! Frontiers in Neurophotonics Symposium 2025 in Bordeaux October 6-9 frontiersneurophotonics.org/2025-speakers/ 🧪

February #ImageOfTheMonth is from @tdhellemmes.bsky.social . GFP expressing Relaxin3 neurons from the nucleus incertus and their projections are followed through the whole mouse brain using Adipoclear+ method and Light Sheet microscopy. Scale:1mm

Happy new year! Let's start 2025 with an #ImageOfTheMonth from N. Bollier @inrae-bfp.bsky.social. Scanning confocal 3D reconstruction of a tomato shoot apical meristem. The fixed meristem was cleared using clearsee and the cell walls are stained by calcofluor white.

Kaleidoscopic view of my tracing experiment, from top to bottom. Our great achievement with @jeremie-bic.bsky.social in @bic-bordeaux.bsky.social for @imn-bordeaux.bsky.social

Icing stars and flowers in electron microscopy. With the courtesy of Isabelle Svahn in @neurobordeaux.bsky.social and @bic-bordeaux.bsky.social

Hello, the BIC is starting its Bluesky experience with its December #ImageOfTheMonth. Beautiful rat neurons imaged in STED 😍 by T.Cloâtre from @iins-bordeaux.bsky.social !

For Christmas this year the BIC asked for a new 🔬booking website and Santa heard us 😊. So now we are asking our users to help us find it the best name. If you have ideas and want to participate please help yourself: forms.gle/GBJ3zymegDSr8p…

The BIC wishes you all a very happy new year 2023! To start well this new year, here is our January newsletter 😊: bic.u-bordeaux.fr/?mailpoet_rout…

Le BIC vous souhaite de bonnes fêtes de fin d'année !

Aujourd'hui le BIC reçoit le cristal collectif du CNRS. Tous les membres de l'équipe tiennent à remercier les utilisateurs grâce à qui nous évoluons au quotidien. Félicitations aux autres Lauréats aquitains des #TalentsCNRS !

Our December newsletter is out 😊 bic.u-bordeaux.fr/?mailpoet_rout…

Today all BIC staff is out for some fun on and around the lake. On the process of considering coming back to the dark imaging rooms or not...

We started our official back to school week with the official picture to advertise our "Cristal collectif du CNRS 2022Like kids we were not really focused first and our photographer was very patient 😅😎thanks @avecunz cnrs.fr/fr/personne/bo…

As everyone, the BIC is getting ready for this new season of its microscopic adventures. To do so we are cleaning the premises, preparing the next trainings and finally release the correction of our summer games : Check this out 👉 bic.u-bordeaux.fr/?mailpoet_rout…

Every summer we offer our users a very special newsletter to keep them focus on microscopy during their vacation 😎🏖️🔬 You can find the 2022 version here: bic.u-bordeaux.fr/bic-summer-gam…

Et hop c'est parti pour le second protocole! Ça explore bien ! #BlobCNRS

Fin de la première semaine de manip. Malgré notre habitude de la paillasse on a transpiré pour assurer la logistique 🥵 Au taquet pour le deuxième protocole la semaine prochaine 💪#BlobCNRS

Breaking news! @BIC_Bordeaux has just been awarded the prestigious “Cristal collectif du CNRS 2022”. We are very proud that our long term team efforts are acknowledged with this award😊🔬 cnrs.fr/fr/personne/cr…

Après un premier faux départ, nous voici relancés avec une souche qui a bien démarré sa phase de réveil 💪! #BlobCNRS

Apparently our students are involved in some post-it contest with the neighboor lab. And of course they started with an obvious piece of art 🔬🤩

Lancement de la phase de réveil hier, on y va timidement mais sûrement #BlobCNRS

Dernière étape de préparation: les géloses pour la phase de réveil. Grâce @fab_cordelieres et à son imprimante 3D on parallélise et on normalise le volume d'agar dans chaque boîte 😅 #BlobCNRS

Avant de se lancer dans le réveil et les premiers protocoles on continue de préparer notre espace de travail... Enfin on s'amuse avec notre espace de travail @fab_cordelieres @Seb_BIC @MonicaFM_BIC @ChristelPoujol #BlobCNRS

En pleine préparation de l'espace de travail, test de montée en température en cours! #BlobCNRS

Le BIC a reçu son blob pour participer à l'expérience du cnrs 😍 #BlobCNRS

The BIC Workshop is about to start: the team is ready !

🚨Mathieu Ducros @BIC_Bordeaux and @galland_remi from @iins_bordeaux are organizing an Inserm Workshop about Light Sheet Fluorescence Microscopy! Check the info here:Registration deadlin: 4th of March evenium-site.com/site/atelier-d…

🚨The 3rd and last episode of our workshop season is planned for the 9th of March @ 10AM !!! To complete the topic of "protein localization at high resolution", we will present what we can do in CLEM at the BIC ! 🔬 Free registration here: forms.gle/SmXZHqpWgsamL1…

When @fab_cordelieres levels up his nerdiness 😍🤩

When your users are in full Christmas mode you know that holidays are approaching 🎅

Get ready for this: The BIC 2021 advent Calendar is coming! Starting today, around lunch time and for the month to come, we will shed light on BIC users and their applications 🔬🥳

The BIC team enjoys it's last evening at #MiFoBio2021 😊

We are finally back to "in presence" institute meeting 🥳 with @iins_bordeaux ! And to make it even better our beloved Mónica presents expansion microscopy possibilities at the BIC. Go Mónica @Mnica43402552 !!!

Are you missing microscopy during summer time? Check out our last Newsletter 🏖️🔬☀️ bic.u-bordeaux.fr/?mailpoet_rout…

Ingénieur d'étude en#Emploi via @EmploiCnrs bit.ly/3hDjEQd

🚨The 2nd episode of our workshop season is planned for the 1st of July @ 10AM !!! To complete the topic of "protein localization at high resolution", we will present what we can do in super-resolution light microscopy ! 🔬 Free registration here: forms.gle/Kb3D8ahs7crD8w…