📢A new effector-triggered immunity role for GBP1! No place for pathogens to hide now that GBP1 can detect extracellular pathogens that hijack the actin cytoskeleton. Surprise*suprise* GBP1 does this independently of LPS! 🧵 biorxiv.org/content/10.1...

PhD fellowship in biofilm-phage interactions - with Mette Burmølle at University of Copenhagen 🇩🇰 deadline 1 October 2025 employment.ku.dk/faculty?show... #phagesky #microsky

Metagenomics for Microbiology 2nd Ed provides an opportunity to reflect on the growth of the metagenomics field, from new applications to technological advances. The chapters cover methodology, analysis, AI, omics, and more. shop.elsevier.com/books/metage... #microbiome #omics #DataScience

There seems to quite a few new faces lately, so if I haven’t already added you, but you’d like added please let me know and for anyone interested in following more microbial natural products folks, then our starter pack is now 100 strong go.bsky.app/72NeGsT

www.nature.com/articles/s41... #microsky

Capturing 100 years of antibiotic resistance evolution www.ebi.ac.uk/about/news/r... #MicroSky

Pleased to share the new article from UCSD Skaggs School of Pharmacy PharmD/PhD student Daniel Sun focused on repurposing FDA-approved agents to inhibit virulence, restore antibiotic susceptibility, bolster host defenses, and modulate inflammation v. S. aureus www.annualreviews.org/content/jour...

Microbiologist Paula Welander studies fossils, but not dinosaur bones or ammonite imprints. Instead, she looks for microscopic clues left behind by microbes that lived millions of years ago.

It was a pleasure to meet Gadi Frankel from @imperialcollegeldn.bsky.social @scelse.bsky.social and host a dinner at Chopsuey with @cwhitch.bsky.social and @figlegend.bsky.social

(1/9)For over a century, antibiotics were found by slow, painstaking, serendipitous screening. Today we share a different path: the first demonstration of deep reinforcement learning (RL) for antibiotic discovery.

Delighted to see our paper studying the evolution of plasmids over the last 100 years, now out! Years of work by Adrian Cazares, also Nick Thomson @sangerinstitute.bsky.social - this version much improved over the preprint. Final version should be open access, apols. Thread 1/n

New in JB: Ma, Wang & Li review the role of DNA methylation in regulating pathogenesis, drug resistance, biofilm formation, adhesion, and motility and more! journals.asm.org/doi/10.1128/... @asm.org #JBacteriology

apnews.com/article/cdc-... bacteria' cases are increasing in the US

Ever wondered how to position organelles in bacteria? Wonder no more! Happy to have contributed to this fantastic story from @cellforganized.bsky.social' lab. The avenues this opens in the synthetic biology space are enormous! Movie: Carboxysomes positioned in E. coli! Preprint: shorturl.at/D6xVg

Nice writeup of our discovery of the first Legionella phage from @uoftmedicine.bsky.social. A special thanks to Betty Zou for being interested in our latest work. temertymedicine.utoronto.ca/news/scienti...

Beautiful 🤩 I love that there are still mysteries like this waiting to be unraveled.. (also how much does this look like an impressionist portrait of GroEL-GroES??)

#Fungi in the gut #microbiome ( #mycobiome) are somewhat neglected. This study of gut fungal profiles across natural populations of humans & non-human primates, by @symbionticism.bsky.social &co, reveals significant fungal cospeciation patterns in #hominids @plosbiology.org 🧪 plos.io/46LX4zD

Day 2 of MHD introductions 😃 Dr Lis Lowe @lislowe.bsky.social The Lowe lab is focussed on microbial glycobiology. They work on bacterial Cazymes from commensals and pathogens, and are particularly interested in enzymes that target microbial glycans such as the cell walls of Mycobacteria.

Next up, Dr Kate Beckham @kshbeckham.bsky.social The Beckham lab is interested mycobacterial membrane transport processes. They focusing on understanding the steps occurring at the mycobacterial outer membrane. www.ncl.ac.uk/cbcb/staff/p...

New in JB: Pinho, Gotz & Peschel review the history of S. aureus as a model for studying bacterial cell biology and pathogenesis. journals.asm.org/doi/10.1128/... This papers is part of the History of Microbial Model collection: journals.asm.org/topic/sss-ta... @asm.org #JBacteriology

A new #CryoET study shows that the protein ZapD helps organise FtsZ filaments into stable ring-like structures in building bacterial division machinery. buff.ly/saLPqJM

www.nature.com/articles/d41... #MicroSky

Love this new paper from @gtrubl.bsky.social and @alexjprobst.bsky.social on the importance of accurate use of terminology in microbial ecology. I’ve seen a lot of use of lysogenic instead of temperate recently so it’s nice to see that distinction being made. doi.org/10.1111/1462...

Happy to share that our story on the bacterial archaellum was published today in @natmicrobiol.nature.com www.nature.com/articles/s41... Congrats to the authors: @sshamphavi.bsky.social @loumollat.bsky.social @mariejoest.bsky.social Najwa Taib and @sgribaldo.bsky.social

🫴 Wow: ComFB is a widespread family of c-di-NMP receptor proteins! 👇👇👇 www.pnas.org/doi/10.1073/... @pnas.org #subtiwiki #subtilis

The @cshlaboratory.bsky.social Asia hands-on Course in Pseudomonas SynBio is coming to an end 😢 after 2 weeks of great science, cool experiments, enthusiastic & hard-working int students & super-pro support by local staff. What else one can ask for? Can you decipher the meaning of the course logo 👇?

Hydrogen sulfide production distinguishes Salmonella from close relatives, but its biological significance remains obscure. This study uncovers the secret: Salmonella uses hydrogen sulfide production as a weapon to outcompete E. coli and gain a foothold in the gut. www.pnas.org/doi/10.1073/...

On this week, 40 years ago, my friend Ralph Isberg, then a postdoc with Stan Falkow, reported the discovery of the 1st invasin gene in @nature.com "We report here the identification of a single genetic locus from this organism (Y. pseudotuberculosis) that is sufficient to convert the innocuous

#NewResearch Computational analysis and pairwise assays reveal that bacterial topoisomerase IV is a target of microbially produced phenazines, which informs synthetic-community design to treat fungal crop infection. #MicroSky www.nature.com/articles/s41...

www.nature.com/articles/s41... #microsky

Thrilled to share our two latest papers with the @tcostalab.bsky.social lab! In the first, we uncover a new mechanism of satellite transfer: cf-PICIs hijack tails from diverse phages to spread across species. @imperialcollegeldn.bsky.social www.cell.com/cell/fulltex...

Super cool Pseudomonas-Bacillus interaction paper in @natmicrobiol.nature.com from Yun Chen with @gabrieleberg.bsky.social Phenazines shape Gram+ abundance & influence Bacillus cell biology Phenazines contribute to microbiome dynamics by targeting topoisomerase IV www.nature.com/articles/s41...

Story on our Asgard microtubule paper by Nikki Greenwood: www.quantamagazine.org/tiny-tubes-r... Thanks to all interviewees🎤

Looking for a new approach to studying or eliminating phages? Check out our study introducing anti-phage ASOs (antisense oligos) out in @Nature today. nature.com/articles/s4158…

www.nature.com/articles/s41... #microsky

Dissecting microbial communities with single-cell transcriptome analysis www.science.org/doi/abs/10.1... #jcampubs

Prof Alain Filloux (@fillouxlab.bsky.social) will join an international faculty to lecture at this intensive course "Advanced Synthetic Biology & Metabolic Engineering of Pseudomonas" in Suzhou, 7–21 Sep 2025. See www.csh-asia.org?content/2645

Delighted to share our recently published work! Ever wondered how Klebsiella (and others) deals with capsule production’s costs ? The paper: journals.asm.org/doi/10.1128/... Thread👇

On our way to the Parsek/Woz retreat in Leavenworth, WA!

So excited our antibiotic potentiation story is out 🤩 Led by the extraordinary @manonlang.bsky.social with @fox-science.bsky.social & @amazeld.bsky.social +amazing collaborators @immunobladder.bsky.social @imaneelmeouche.bsky.social 🦠 We believe it can make a difference in #AMR infections!

Excited about our most recent collaboration with the Wong lab, lead by William Schmidt, describing a T4P and CdrA-mediated mechanism of sensing surface EPS. Fun stuff and great work William and team. www.nature.com/articles/s41...

www.tandfonline.com/doi/full/10.... #microsky #microbiome #glycotime

Excited to share our latest work, driven by my recently graduated PhD student Kaitlyn Barrack, exploring the mechanisms of bacterial dysbiosis in the CF gut - including a role for a colorectal cancer-associated genotoxin in this competition. www.biorxiv.org/content/10.1... @kbarrack.bsky.social

“A journey into the microbial world” -that’s how Prof @fillouxlab.bsky.social, SCELSE Centre Director, welcomed over 200 guests to our biggest Open House yet. From fireside chats to immersive exhibits and lab tours, visitors explored how microbes shape health, food, oceans, and the future.

New review 🔥 Single-cell RNA-Seq has been revolutionary for studying eukaryotic cells and now it's time for it to do the same for microbes! We describe the technology for single-bacterium RNA-Seq & the questions now studied using it.🧵⬇️ science.org/doi/10.1126/... @andrewpountain.bsky.social

journals.plos.org/plosbiology/... #MicroSky

Check out our latest paper, a huge effort led by @benjaminguinet.bsky.social and @tvdvalk.bsky.social 🦣🔍🦠 Paper: www.cell.com/cell/abstrac...

Savour the fine flavour of our September issue, featuring... 〰️Bacterial prions in phage defence 💊Antibiotics from archaea 🔺Spike complexes in Sabiá, Junin and Machupo viruses 🛡️Aggresomes and mRNA protection 🤝A call for early-career teams ...and more, here 👇 www.nature.com/nmicrobiol/v...

Excited to share our new publication, out today in Nature! www.nature.com/articles/s41.... @kanchanj.bsky.social led this fascinating fungal-bacterial interaction project. We are grateful for our wonderful collaborators Brian Peters and David Underhill.