Anthony Vecchiarelli
@cellforganized.bsky.social
📤 778
📥 427
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How do bacteria organize their innards? Associate Prof at UMich
Canadian Premier Soccer final is the most bad ass soccer game I've seen.
39 minutes ago
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Anthony Vecchiarelli
Mark O. Martin
2 days ago
Friday means a new
#MattersMicrobial
podcast. This week, Dr. Hannah Ledvina joins the
#QualityQuorum
to chat about how bacteria can shield themselves against Bdellovibrio attack! Please spread the
#GoodMicrobialWord
. @univpugetsound @ASMicrobiology @microbe.tv
youtu.be/n31kkw576GE?...
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Anthony Vecchiarelli
Alex Merz 🇺🇸🇨🇦🇺🇦
5 days ago
One of the most useful resources for anyone who uses fluorescence methods.
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Anthony Vecchiarelli
Jonathan Eisen
8 days ago
Right now this is my favorite
@inaturalist.bsky.social
observation
www.inaturalist.org/observations...
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Blue Jay (Cyanocitta cristata)
Blue Jay from Montgomery County, MD, USA on January 18, 2024 at 10:35 AM by Jonathan Eisen
https://www.inaturalist.org/observations/197123979
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Anthony Vecchiarelli
Mark O. Martin
9 days ago
I had the most awesome time recording next week's
#MattersMicrobial
podcast session with Dr. Hannah Ledvina of the University of Michigan. Her work on the "shield" that E. coli can make against Bdellovibrio attack was amazing. Plus, we share many common enthusiasms. It was a proper nerdfest.
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Anthony Vecchiarelli
🇨🇦 👊🇨🇦
16 days ago
LA Dodger’s Freddie Freedom speaks about his Canadian Mom. He seems like a really nice guy, I hope his team comes in 2nd place.
#Canada
#TorontoBlueJays
#LADodgers
#WorldSeries
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Willem van Schaik
16 days ago
Complete nonsense. My advice to post-graduate researchers is to always preprint their work, as it will improve their visibility while the manuscript is going through a (frequently very long) peer review process.
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Anthony Vecchiarelli
David Ho
16 days ago
Always read
@jtemple.bsky.social
, especially when he quotes me. 😆 R&D on CO₂ removal (CDR) should be funded and led by governments, like the Manhattan Project minus the nuclear bomb. That way we can figure out what works and what doesn't technologically, environmentally, socially, etc.
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Julie Biteen
20 days ago
Thrilled to share our multidisiplinary work on how genome-wide DNA bridging by H-NS reshapes the stationary phase bacterial nucleoid and affects the transcriptional landscape. With Xindan Wang and
@meyerroc.bsky.social
www.biorxiv.org/content/10.1...
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Bacteria use paralog teamwork to survive stress. H-NS forms fluid condensates; its partner StpA forms rigid fibrils. Together, they balance flexibility & stability to keep genes properly regulated under pressure.
#PhaseSeparation
#Bacteria
www.biorxiv.org/content/10.1...
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Paralogs with distinct phase behaviors broaden the in vivo stress response range of condensates
Paralogs are widespread, but their physiological roles are often masked by redundancy. H-NS, a nucleoid-associated protein in Gram-negative bacteria, typically coexists with paralogs such as StpA, who...
https://www.biorxiv.org/content/10.1101/2025.10.13.682129v1.abstract
20 days ago
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Anthony Vecchiarelli
JacobsWagnerLab
21 days ago
Hello! The Jacobs-Wagner lab is finally on Bluesky. We’re excited to celebrate science (and scientists!), share our research, and interact with the community. We look forward to connecting with friends and colleagues across the world.
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Fusion Conferences
24 days ago
We’re excited to announce the incredible speaker line-up for the Prokaryotic Cell Biology Conference! Join the leading researchers as they explore the latest advances in Nanoimaging, Cell Growth and Cellular Structures. Join our speakers & register today! ➡️https://bit.ly/47rtkbw
#ProkaryoticCellBio
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Anthony Vecchiarelli
Valerio Sorichetti
25 days ago
Our paper on chromosome segregation in the archaeon Sulfolobus Acidocaldarius has been published in PNAS! This has been a great collaboration with
@joeparham19.bsky.social
and the rest of
@buzzbaum.bsky.social
's team. Stay tuned for more to come!😉
@istaresearch.bsky.social
doi.org/10.1073/pnas...
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Temporal and spatial coordination of DNA segregation and cell division in an archaeon | PNAS
Cells must coordinate DNA segregation with cytokinesis to ensure that each daughter cell inherits a complete genome. Here, we explore how DNA segre...
https://doi.org/10.1073/pnas.2513939122
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Ariane Briegel
26 days ago
Interested in bacterial sensing, signaling and regulation? Come join us in January at the GRC in sunny California!
www.grc.org/sensory-tran...
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2026 Sensory Transduction in Microorganisms Conference GRC
The 2026 Gordon Research Conference on Sensory Transduction in Microorganisms will be held in Ventura, California. Apply today to reserve your spot.
https://www.grc.org/sensory-transduction-in-microorganisms-conference/2026/
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Anthony Vecchiarelli
Luciana Santoferrara
26 days ago
We have a Tenure-Track Assistant Professor position in Microbiology available! Come and join great students and colleagues at Hofstra Biology. Please apply using the link below and/or spread the word!
hofstra.peopleadmin.com/postings/6542
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Assistant Professor of Microbiology
https://hofstra.peopleadmin.com/postings/6542
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MCDB Assistant Professor Faculty Search. Please Repost! Applications Due Oct 15th (TOMORROW!) We welcome applications from all areas of physiology and neuroscience - spanning molecular, cellular, systems, and organismal levels. More information can be found HERE:
lsa.umich.edu/mcdb/news-ev...
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MCDB Opens Search for Faculty | U-M LSA Molecular, Cellular, and Developmental Biology (MCDB)
MCDB welcomes applications at the Assistant Professor level from outstanding biological scientists in all areas of physiology and neuroscience, spanning molecular, cellular, systems, and organismal le...
https://lsa.umich.edu/mcdb/news-events/all-news/search-news/faculty-search1.html
26 days ago
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Anthony Vecchiarelli
Jen Herman 🌪️
27 days ago
Made some mugs Word cloud made from 100+ different obituaries of exemplary scientists Obituaries were submitted by 1st yr grad students for a course I teach on scientific values (5 yrs total) No menchie indirects, awards, or impact factor...
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Anthony Vecchiarelli
Tung Le
30 days ago
new preprint from our group & Antoine Hocher:
www.biorxiv.org/content/10.1...
A fantastic collaboration with Antoine, with Jovana Kaljevic' initiated the collaboration and drives the project.
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Versatile NTP recognition and domain fusions expand the functional repertoire of the ParB-CTPase fold beyond chromosome segregation
Nucleotide triphosphate (NTP)-dependent molecular switches regulate essential cellular processes by cycling between active and inactive states through nucleotide binding and hydrolysis. These mechanis...
https://www.biorxiv.org/content/10.1101/2025.10.10.680097v1
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Anthony Vecchiarelli
Andy Rivkin
about 1 month ago
🧪
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Anthony Vecchiarelli
Benoit Bruneau
about 1 month ago
Hey Americans! How’s that baseball series going?
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Anthony Vecchiarelli
Jeremy Berg
about 1 month ago
I have been trying to get this published as an op-ed, but I am going to post it here since I think it is timely in light of the "consent" extortion events. Deafening Quiet from the Scientific Establishment
jeremymberg.github.io/jeremyberg.g...
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https://jeremymberg.github.io/jeremyberg.github.io/Scientific%20Establishment-Berg.pdf
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Amelia Randich
about 1 month ago
Interested in a tenure track position teaching and doing research with undergrads at a PUI? We are looking for a broadly-defined microbiologist who can teach Med Micro and Immunology. Apply at
universityofscrantonjobs.com/postings/8308
. Pls share widely to feeds (& on twitter if you still tweet)! 🦠
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Anthony Vecchiarelli
New PrePrint from the Vecchiarelli and Mosalaganti (
@shyamalm.bsky.social
) labs! 🧵 Collaboration with the Giessen and Pi labs Congratulations to co-first authors Y Hoang (
@hoanghamyy.bsky.social
) and Pankaj Jadhav!
www.biorxiv.org/content/10.1...
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Engineering Spatial Control of Bacterial Organelles
Bacteria were once thought to lack organelles, but it is now clear they confine cellular reactions using an array of membrane- and protein-based compartments. A central question, however, is how bacte...
https://www.biorxiv.org/content/10.1101/2025.09.22.677801v1
about 2 months ago
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Anthony Vecchiarelli
Tung Le
about 1 month ago
Independent research fellowships leading to tenured positions at the John Innes Centre. Repost = nice. Thank you very much!!!
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Anthony Vecchiarelli
Ryan Marino, MD
about 1 month ago
This is why we fund scientists to study things like oyster slobber even if you don’t think it sounds important
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Anthony Vecchiarelli
Jutras Lab
about 1 month ago
Invited to give a talk by graduate students-who DRIVE research nationwide-is easily one of the greatest honors for a PI. It’s even better when one of your former mentees is the host! Thank you Tanner and
@harvard.edu
Micro for being a bright light in these dark times. 🙏 Science will prevail 💪
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Anthony Vecchiarelli
The Robert Mehrabian College of Engineering
about 1 month ago
We kicked off the new school year with the launch of the BioFoundry for Extreme and Exceptional Fungi, Archaea and Bacteria (ExFAB). The new facility will allow researchers to make novel discoveries using previously unstudied microbes that could generate advances in biotechnology & biomanufacturing.
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Anthony Vecchiarelli
Manuel Thery
about 1 month ago
THE Erwin Frey, talking about self-organization in biological systems. Title of the seminar serie suggests it might be intended for physicists.
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Anthony Vecchiarelli
Benoit Bruneau
about 1 month ago
thank you to all the NIH staff who stand by their duty and put in heroic efforts to get it done. I'll never forget it and will be eternally grateful.
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Anthony Vecchiarelli
Jeremy B. Yoder 🧬📊🌿🏳️🌈🖖🏻
about 1 month ago
We've already got hundreds of students and mentors here, sharing how the sudden policy change has derailed plans. We're looking at formally "delivering" results to NSF leadership tomorrow, please do keep sharing and spreading the word:
laurenkuehne.github.io/grfpChanges/
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Anthony Vecchiarelli
bioRxiv Microbiology
about 1 month ago
Unannotated translation products are widespread in model E. coli
https://www.biorxiv.org/content/10.1101/2025.09.25.678689v1
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Anthony Vecchiarelli
Emmanuele Severi
about 1 month ago
www.nature.com/articles/s41...
#microsky
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Molecular basis of ParA ATPase activation by the CTPase ParB during bacterial chromosome segregation - Nature Communications
ParABS systems partition chromosomal DNA and low-copy plasmids in bacteria. Here, the authors elucidate the mode of interaction between ParA and ParB and clarify how ParB stimulates the ATPase activity of ParA to drive the segregation process.
https://www.nature.com/articles/s41467-025-63976-0
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Anthony Vecchiarelli
Géraldine Laloux
about 2 months ago
📝New preprint!
#MicroSky
🕰️We chart the full, synchronized lifecycle of a predatory bacterium using Hi-C, RNA-seq, ChIP-seq & microscopy. 🧬We uncover dramatic shifts in nucleoid architecture & transcription, tightly coordinated with predation.
www.biorxiv.org/content/10.1...
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Dynamics and interplay of gene expression and chromosome organization across a predatory lifecycle
The obligate predatory bacterium Bdellovibrio bacteriovorus alternates between a motile attack phase and a growth phase inside another bacterium, during which it undergoes multiple rounds of DNA repli...
https://www.biorxiv.org/content/10.1101/2025.09.24.678257v1
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Anthony Vecchiarelli
My MCDB dept is accepting applications for a faculty position at the Assistant Professor level! Applications Due by October 15, 2025 We welcome applications from all areas of physiology and neuroscience, spanning molecular, cellular, systems, and organismal levels.
lsa.umich.edu/mcdb/news-ev...
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MCDB Opens Search for Faculty | U-M LSA Molecular, Cellular, and Developmental Biology (MCDB)
MCDB welcomes applications at the Assistant Professor level from outstanding biological scientists in all areas of physiology and neuroscience, spanning molecular, cellular, systems, and organismal le...
https://lsa.umich.edu/mcdb/news-events/all-news/search-news/faculty-search1.html
3 months ago
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Anthony Vecchiarelli
Géraldine Laloux
about 2 months ago
🚨New paper out!
#MicroSky
Studying obligate predators like Bdellovibrio bacteriovorus is tricky—essential genes for predation are also essential for survival. We expanded its genetic toolbox: 🧬promoters to fine-tune expression 🧬IPTG-inducible system 🧬CRISPRi for rapid knockdown
bit.ly/46GUn2c
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Expanding the genetic toolbox of the obligate predatory bacterium Bdellovibrio bacteriovorus with inducible gene expression and CRISPR interference
Inducible gene expression and CRISPR interference-mediated depletion in the predatory bacterium Bdellovibrio bacteriovorus.
https://academic.oup.com/microlife/article/doi/10.1093/femsml/uqaf021/8245127
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Anthony Vecchiarelli
Shyamal
about 2 months ago
Ever wondered how to position organelles in bacteria? Wonder no more! Happy to have contributed to this fantastic story from
@cellforganized.bsky.social
' lab. The avenues this opens in the synthetic biology space are enormous! Movie: Carboxysomes positioned in E. coli! Preprint:
shorturl.at/D6xVg
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New PrePrint from the Vecchiarelli and Mosalaganti (
@shyamalm.bsky.social
) labs! 🧵 Collaboration with the Giessen and Pi labs Congratulations to co-first authors Y Hoang (
@hoanghamyy.bsky.social
) and Pankaj Jadhav!
www.biorxiv.org/content/10.1...
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Engineering Spatial Control of Bacterial Organelles
Bacteria were once thought to lack organelles, but it is now clear they confine cellular reactions using an array of membrane- and protein-based compartments. A central question, however, is how bacte...
https://www.biorxiv.org/content/10.1101/2025.09.22.677801v1
about 2 months ago
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Anthony Vecchiarelli
Princess Vimentin PhD | Cancer Biologist
about 2 months ago
A must read. It takes years to see a spark transformed to a groundbreaking treatment. It all begins with basic research. Due to sustained
#NIH
funding, we have better therapeutics, cancer detection, vaccines. We are like 1930s Germany. 🧪
www.infotimes.us/basic-scienc...
via
@markhisted.org
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Basic Science Is The Foundation Of Future Cures
Injecting partisan politics into American basic science would be terrible for the US: for the economy, and for development of future treatments for diseases like schizophrenia and Alzheimer's.
https://www.infotimes.us/basic-science-builds-future-cures/
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Anthony Vecchiarelli
eLife
about 2 months ago
A new
#CryoET
study shows that the protein ZapD helps organise FtsZ filaments into stable ring-like structures in building bacterial division machinery.
buff.ly/saLPqJM
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Erin Goley
about 2 months ago
🚨🚨🚨Calling all Caulophiles and Alpha aficionados - stayed tuned for a virtual CauloCon in early 2026. And HOPEFULLY an in person alpha meeting in 2027!! DM me or
@chienlab.bsky.social
w questions or to stay in the know.
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Anthony Vecchiarelli
Epigenetics Society
about 2 months ago
@laskerfdn.bsky.social 2025
#LaskerAward
winner Lucy Shapiro asked: How do organisms translate information from a linear genetic code into 3D structures? With that, she opened a new field. Also studied bacterial DNA methylation & gene expression.
www.pnas.org/doi/10.1073/pnas.2519777122
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Anthony Vecchiarelli
Erin Goley
about 2 months ago
So proud to have trained with Lucy. She is an exceptional scientist, exceptional person, and exceptional mentor. Huge congrats and so well-deserved.
laskerfoundation.org/winners/pion...
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Pioneering approach to bacterial cell biology & national leadership - Lasker Foundation
Lucy Shapiro
https://laskerfoundation.org/winners/pioneering-approach-to-bacterial-cell-biology-national-leadership/
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Anthony Vecchiarelli
Jörg Vogel
2 months ago
Looking for a new approach to studying or eliminating phages? Check out our study introducing anti-phage ASOs (antisense oligos) out in @Nature today.
nature.com/articles/s4158…
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Anthony Vecchiarelli
María Santos-Merino
2 months ago
So happy to see this publication finally out! Congratulations and thank you to all the authors!
www.pnas.org/doi/10.1073/...
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Mutations in the circadian cycle drive adaptive plasticity in cyanobacteria | PNAS
Circadian clocks allow organisms to anticipate daily fluctuations in light and temperature, but how this anticipatory role promotes adaptation to d...
https://www.pnas.org/doi/10.1073/pnas.2506928122
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Anthony Vecchiarelli
STCmicrobeblog
2 months ago
we fully endorse this statement by
@asm.org
. period
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Anthony Vecchiarelli
Carl Zimmer
2 months ago
Yesterday the president demanded that evidence about Covid vaccines be shown to the public. Today
@apoorvanyt.bsky.social
& I run through some of the studies made public over the past 4+ years that show that the vaccines work. Gift link:
nyti.ms/46k17Tq
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https://nyti.ms/46k17Tq
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Anthony Vecchiarelli
Jeremy Berg
2 months ago
My quote of the day Nobody ever thanks you for saving them from the disease they didn't know they were going to get. William Foege
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Pierre Polyester
2 months ago
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Anthony Vecchiarelli
Ran Blekhman
2 months ago
More foundations should do this: "Funding is exclusively available to applicants who have already received federal funding (e.g., from the NIH, CDC, NSF) for their health equity research, but have since had their funding rescinded due to federal administrative actions"
www.rwjf.org/en/grants/ac...
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Rapid Response: Reinvesting in Racial and Indigenous Health Equity Research
The purpose of this call for proposals is to meet the current moment by supporting timely, actionable health equity research that has been interrupted by shifts in federal funding.
https://www.rwjf.org/en/grants/active-funding-opportunities/2025/rapid-response-reinvesting-in-racial-and-indigenous-health-equity-research.html
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Anthony Vecchiarelli
Gregg Gonsalves
2 months ago
AND NOW THE SENIOR CDC LEADERS HAVE JOINED THE WALK OUT!
www.youtube.com/watch?v=KZ7Q...
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LIVE: CDC staff plan walkout at Atlanta HQ after Trump firings
YouTube video by Associated Press
https://www.youtube.com/watch?v=KZ7QvPHjKRU
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