How could a simple self-replicating system emerge at the origins of life? RNA polymerase ribozymes can replicate RNA, but existing ones are so large that their self-replication seems impossible. Could they be smaller? Excited to share our latest work in @science.org on a new small polymerase. 1/n

Great fun working with Manajit Hayer-Hartl and her amazing team at @mpibiochem.bsky.social bringing this work on the beta-carboxyome protein ApN (CcmN) together.

Look at this 🙂 #CryoEM Structural basis for CTCF-mediated chromatin organization by @lucas.farnunglab.com @voslab.org www.biorxiv.org/content/10.6...

Functional characterisation of bicarbonate transporters from the cyanobacterial SbtA2 family and subsequent expression in tobacco academic.oup.com/jxb/article/... @jxbotany.bsky.social

SAGA1 and SAGA2 localize the starch sheath to the pyrenoid in Chlamydomonas reinhardti @mjonikas.bsky.social www.biorxiv.org/content/10.6...

How does molecular valency shape condensate assembly and function? We used the CO2-fixing organelle in algae—the pyrenoid—to find out… 🧵 Preprint here!: www.biorxiv.org/content/10.6... @cellarchlab.com @phaips.vd.st @biologyatyork.bsky.social #Rubisco #PhaseSeparation #Condensates #Pyrenoid

Next week we will have the pleasure of hosting Dr. Tanner Robison. Tanner will be talking about carbon concentrating mechanisms and hornwort pyrenoids ! @btiscience.bsky.social @ulaval.ca @ulaval.ca www.nature.com/articles/s41...

Sticker number modulates pyrenoid condensate assembly to support algal fitness Looking forward to reading this! @james-r-barrett.bsky.social @phaips.vd.st ps.vd.st www.biorxiv.org/content/10.6...

Having fun with the microscope lately. Here’s one of my favourite artsy and slightly psychedelic shots of #Marchantia chloroplasts and a fluorescent membrane reporter. (z-stack maximum projection)

The people of Minnesota did that. Not Schumer and Jeffries, not Walz and Frey, not the standard-bearers of decorum. The People.

brass solidarity band performing “stand by me” in the streets of whittier next to alex pretti’s memorial. the crowd started chanting “the people united will never be defeated” so they incorporated it into the song. i love minneapolis

From my go-to bikepacking website where I've never read anything remotely political. That's where we're at now bikepacking.com/news/alex-pr...

Got this from a first-year law student today. I’m going to turn comments and quotes off because I am going to respond in my own way and am not looking for advice. But I think people should see it.

Memory is a fragile thing in this moment, so it is important to keep in mind that Hakeem Jeffries refused to whip his caucus against ICE funding earlier this week.

It’s possible we live in a country where 25-35% of the population thinks it’s good and just that masked armies are sent into blue cities to execute people who vote the wrong way

One court decision, two different headlines. Guardian on the left, NY Times on the right. Which one more directly conveys information and the stakes to the reader?

Interested in learning about hornworts? Check out the on-line hornwort class www.eaglehill.us/programs/sem...

Carney in Davos:

Yesterday it was cows using tools, today its penguins using satellite imagery.

🧪Scientists from our Haselbach lab captured how proteins begin to fold as they’re being made. Using cryo-EM, they visualised chaperones guiding nascent proteins on the ribosome: https://www.nature.com/articles/s41467-025-67685-6

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Happy to share the pre-print on GEMMIFER, a novel ERF required for the initiation of gemma in Marchantia. One of the coolest phenotypes that I have ever seen. Congratulations to Yuki and Go, who led this research. #PlantScience @biorxiv-plants.bsky.social www.biorxiv.org/content/10.6...

Absolute stunning pyrenoid review well worth the read!

How does protein folding change inside biomolecular condensates? Our new preprint put forwards a framework for predicting this!! 🥳🥳🥳🥳 work by the talented @nathanieldhess.bsky.social

A reminder that not so long ago we honored immigrants in the US, even by carving monuments like this one at Immigration Point, over the Golden Gate connecting the Pacific to SF Bay. @hcrichardson.bsky.social @rebeccasolnit.bsky.social

Border Patrol boss Gregory Bovino caught on a hot mic:

Structure of Chlamydomonas reinhardtii LciA guided the engineering of FNT family proteins to gain bicarbonate transport activity www.nature.com/articles/s41...

our hornwort paper got the cover of the @newphyt.bsky.social nph.onlinelibrary.wiley.com/doi/10.1111/...

The “prosecute the former regime at every level” candidate has my vote in 2028.

You should be embarrassed to be a member of congress and issuing anything other than impeachment resolutions. You're in the model UN. They should give you legos and a propeller hat

Trump bombing random places without the approval of a senate that doesn’t give a shit and couldn’t care less that they were elected to pass laws and declare wars and stuff, it really freaks me out

Before the 1990s, plane crashes caused by microbursts used to kill planeloads of people fairly regularly. Dr. Ted Fujita and NCAR scientists figured out how to detect microbursts and warn pilots about them. Since then? Zero airliner crashes from microbursts.

I had a great time writing this dispatch @currentbiology.bsky.social about Jacob Suissa's recent paper on the link between fern phyllotaxis and vascular architecture. "Evo–devo: Ferns flourished due to developmental covariance between leaves and vasculature" authors.elsevier.com/a/1mH793QW8S...

“Dutch people cycle an average of 2.6km each per day. If this pattern was replicated worldwide, annual carbon emissions would drop by 686 million tonnes. This mammoth figure exceeds the entire carbon footprint of most countries, including the UK, Canada, Saudi Arabia and Australia.” @euronews.com

Our Science paper is out! Huge congratulations to @huabin-zhou.bsky.social, Mike Rosen, and the brilliant @janhuemar.bsky.social @juliamaristany.bsky.social and @kieran-russell.bsky.social from our group News: bit.ly/4avnkAr and bit.ly/3XBGVHS Great perspective by @vram142.bsky.social +K Zhang

WE GOT FERNS, folks. I hope you like ferns. If you don’t, just listen and you will like ferns. 🌿🌿🌿 Dr. Li is hilarious and charming and you will love him. And ferns. In conclusion: ferns. www.alieward.com/ologies/pter...

In the richest city in the richest country on the planet, the thing we can’t afford is to forget those who are left hungry.

POV: you are a young woman celebrating a recent academic success

It is pathetic to see Cornell shrink from one of its foundational principles www.cornellsun.com/article/2025...

Sphagnum moss Imaged live on the FV4000, a new, paradigm shifting, laser scanning confocal microscope from Evident LifeScience (aka Olympus). Green is from the Hyaline Cells and the red from the [chloroplasts in the] Chlorophyllose cells #sciart #microscopes #moss (scale noted in the Alt-text)

An Asgard archaeon with internal membrane compartments Brilliant study led by @fmacleod.bsky.social and Andriko von Kügelgen. Tight collaboration with @buzzbaum.bsky.social and lab. Congrats to all authors! www.biorxiv.org/content/10.1...

it’s not enough. i challenge andrew cuomo to a 1v1 in super smash bros. i need to watch him lose something a third time

Here are some “leaf” or phyllid cells from moss Physcomitrium patens gametophore. Cells are expressing a green fluorescence marker that labels the vacuolar membrane. Chloroplasts' autofluorescence is in magenta. Can you spot dividing chloroplasts? #microscopymonday #moss #plantcells

LA: we will fight you. Chicago: we will fight you. PDX: we will make you endure week after week of of improv theater.

We really enjoyed putting together this Darwin Review for JXB. Fun to think about how carboxysomes work and why plants don't have them. @jxbotany.bsky.social Function, Evolution, and Future of Carboxysomes url: academic.oup.com/jxb/article-...

Did you know tiny algae can "skate" within Arctic sea ice? ⛸️ Our new study in @pnas.org reveals the secret life of ice diatoms: they are actively gliding to navigate the ice! This adds a new dimension to the sea ice ecosystem, revealing an active, dynamic ecological niche. @prakashlab.bsky.social