Tanner R
@tarobison.bsky.social
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📥 362
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Goofy science
pinned post!
News flash nerds: hornworts are awesome
add a skeleton here at some point
about 1 year ago
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Edoardo Gianni
1 day ago
How could a simple self-replicating system emerge at the origins of life? RNA polymerase ribozymes can replicate RNA, but existing ones are so large that their self-replication seems impossible. Could they be smaller? Excited to share our latest work in
@science.org
on a new small polymerase. 1/n
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A small polymerase ribozyme that can synthesize itself and its complementary strand
The emergence of a chemical system capable of self-replication and evolution is a critical event in the origin of life. RNA polymerase ribozymes can replicate RNA, but their large size and structural ...
https://www.science.org/doi/10.1126/science.adt2760
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Ben Long
3 days ago
Great fun working with Manajit Hayer-Hartl and her amazing team at
@mpibiochem.bsky.social
bringing this work on the beta-carboxyome protein ApN (CcmN) together.
add a skeleton here at some point
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Alexis Verger 🧬🧫🧪
5 days ago
Look at this 🙂
#CryoEM
Structural basis for CTCF-mediated chromatin organization by
@lucas.farnunglab.com
@voslab.org
www.biorxiv.org/content/10.6...
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Ryo Yokoyama
8 days ago
Functional characterisation of bicarbonate transporters from the cyanobacterial SbtA2 family and subsequent expression in tobacco
academic.oup.com/jxb/article/...
@jxbotany.bsky.social
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Functional characterisation of bicarbonate transporters from the cyanobacterial SbtA2 family and subsequent expression in tobacco
Abstract. Cyanobacteria rely on bicarbonate (HCO3-) as the primary inorganic carbon (Ci) source for photosynthesis in aquatic environments. To use this Ci
https://academic.oup.com/jxb/article/doi/10.1093/jxb/erag055/8466555
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Ben Long
15 days ago
SAGA1 and SAGA2 localize the starch sheath to the pyrenoid in Chlamydomonas reinhardti
@mjonikas.bsky.social
www.biorxiv.org/content/10.6...
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https://www.biorxiv.org/content/10.64898/2026.01.27.702031v1
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James Barrett
15 days ago
How does molecular valency shape condensate assembly and function? We used the CO2-fixing organelle in algae—the pyrenoid—to find out… 🧵 Preprint here!:
www.biorxiv.org/content/10.6...
@cellarchlab.com
@phaips.vd.st
@biologyatyork.bsky.social
#Rubisco
#PhaseSeparation
#Condensates
#Pyrenoid
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JCarlos Villarreal
16 days ago
Next week we will have the pleasure of hosting Dr. Tanner Robison. Tanner will be talking about carbon concentrating mechanisms and hornwort pyrenoids !
@btiscience.bsky.social
@ulaval.ca
@ulaval.ca
www.nature.com/articles/s41...
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Sticker number modulates pyrenoid condensate assembly to support algal fitness Looking forward to reading this!
@james-r-barrett.bsky.social
@phaips.vd.st
ps.vd.st
www.biorxiv.org/content/10.6...
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Sticker number modulates pyrenoid condensate assembly to support algal fitness
The valency of intrinsically disordered proteins underpins liquid-liquid phase separation (LLPS), yet how this parameter shapes condensate function and cellular fitness remains poorly understood. Here we exploit the algal pyrenoid—a minimal, two component LLPS system—to directly link condensate properties to physiological performance. Pyrenoid assembly is driven by a disordered, multivalent Linker protein that binds Rubisco at symmetry-related surface sites, with the number of binding motifs (″stickers″) varying across species. Using Chlamydomonas reinhardtii , we systematically tuned sticker number from two to nine and examined effects on Rubisco condensation, pyrenoid architecture and CO2 fixation. Three stickers were sufficient for condensation in vitro, but at least four were required for pyrenoid assembly in vivo. Cryo-electron tomography and single-molecule tracking revealed that increasing sticker number enhances Rubisco packing and mobility, while time-resolved imaging and competition assays demonstrated that sticker number governs the kinetics of pyrenoid formation and determines cellular fitness under fluctuating carbon conditions. Our findings establish sticker number as an evolutionary tuning parameter that balances condensate formation, dynamics, and function, providing a quantitative framework for linking the molecular grammar of phase separation to biological fitness. ### Competing Interest Statement The authors have declared no competing interest. EPSRC, EP/W024063/1
https://www.biorxiv.org/content/10.64898/2026.01.27.701992v1
15 days ago
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Darius KosmĂĽtzky
18 days ago
Having fun with the microscope lately. Here’s one of my favourite artsy and slightly psychedelic shots of
#Marchantia
chloroplasts and a fluorescent membrane reporter. (z-stack maximum projection)
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Sean T. Collins
19 days ago
The people of Minnesota did that. Not Schumer and Jeffries, not Walz and Frey, not the standard-bearers of decorum. The People.
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taylr
19 days ago
brass solidarity band performing “stand by me” in the streets of whittier next to alex pretti’s memorial. the crowd started chanting “the people united will never be defeated” so they incorporated it into the song. i love minneapolis
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Christophe 🔬 L
19 days ago
From my go-to bikepacking website where I've never read anything remotely political. That's where we're at now
bikepacking.com/news/alex-pr...
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Alex Pretti, Killed by ICE, Was One of Us
Yesterday morning in Minneapolis, ICE agents murdered a member of our community, 37-year-old Alex Pretti. Learn more here...
https://bikepacking.com/news/alex-pretti-tribute/
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Evan Bernick, a finite mode with a smol hooman and a lorg floof
20 days ago
Got this from a first-year law student today. I’m going to turn comments and quotes off because I am going to respond in my own way and am not looking for advice. But I think people should see it.
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Kaitlin Is Just Getting Started
21 days ago
Memory is a fragile thing in this moment, so it is important to keep in mind that Hakeem Jeffries refused to whip his caucus against ICE funding earlier this week.
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Ray Delahanty | CityNerd
21 days ago
It’s possible we live in a country where 25-35% of the population thinks it’s good and just that masked armies are sent into blue cities to execute people who vote the wrong way
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Don Moynihan
24 days ago
One court decision, two different headlines. Guardian on the left, NY Times on the right. Which one more directly conveys information and the stakes to the reader?
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JCarlos Villarreal
24 days ago
Interested in learning about hornworts? Check out the on-line hornwort class
www.eaglehill.us/programs/sem...
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Eiko Fried
24 days ago
Carney in Davos:
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Iain Roberts
25 days ago
Yesterday it was cows using tools, today its penguins using satellite imagery.
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IMP
26 days ago
🧪Scientists from our Haselbach lab captured how proteins begin to fold as they’re being made. Using cryo-EM, they visualised chaperones guiding nascent proteins on the ribosome:
https://www.nature.com/articles/s41467-025-67685-6
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đź‘€
add a skeleton here at some point
27 days ago
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Facundo Romani
28 days ago
Happy to share the pre-print on GEMMIFER, a novel ERF required for the initiation of gemma in Marchantia. One of the coolest phenotypes that I have ever seen. Congratulations to Yuki and Go, who led this research.
#PlantScience
@biorxiv-plants.bsky.social
www.biorxiv.org/content/10.6...
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Philippe Van der Stappen
about 1 month ago
Absolute stunning pyrenoid review well worth the read!
add a skeleton here at some point
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Jerelle Joseph
about 1 month ago
How does protein folding change inside biomolecular condensates? Our new preprint put forwards a framework for predicting this!! 🥳🥳🥳🥳 work by the talented @nathanieldhess.bsky.social
add a skeleton here at some point
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Frank Buffum
about 1 month ago
A reminder that not so long ago we honored immigrants in the US, even by carving monuments like this one at Immigration Point, over the Golden Gate connecting the Pacific to SF Bay.
@hcrichardson.bsky.social
@rebeccasolnit.bsky.social
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Ed Lynch
about 1 month ago
Border Patrol boss Gregory Bovino caught on a hot mic:
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Ben Long
about 1 month ago
Structure of Chlamydomonas reinhardtii LciA guided the engineering of FNT family proteins to gain bicarbonate transport activity
www.nature.com/articles/s41...
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Client Challenge
https://www.nature.com/articles/s41477-025-02200-9
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Tanner R
JCarlos Villarreal
about 1 month ago
our hornwort paper got the cover of the
@newphyt.bsky.social
nph.onlinelibrary.wiley.com/doi/10.1111/...
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Ken Jennings
about 1 month ago
The “prosecute the former regime at every level” candidate has my vote in 2028.
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Better Things Are Possible
about 1 month ago
You should be embarrassed to be a member of congress and issuing anything other than impeachment resolutions. You're in the model UN. They should give you legos and a propeller hat
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Big Joel
about 1 month ago
Trump bombing random places without the approval of a senate that doesn’t give a shit and couldn’t care less that they were elected to pass laws and declare wars and stuff, it really freaks me out
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Tanner R
about 2 months ago
Before the 1990s, plane crashes caused by microbursts used to kill planeloads of people fairly regularly. Dr. Ted Fujita and NCAR scientists figured out how to detect microbursts and warn pilots about them. Since then? Zero airliner crashes from microbursts.
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Sandy Hetherington
2 months ago
I had a great time writing this dispatch
@currentbiology.bsky.social
about Jacob Suissa's recent paper on the link between fern phyllotaxis and vascular architecture. "Evo–devo: Ferns flourished due to developmental covariance between leaves and vasculature"
authors.elsevier.com/a/1mH793QW8S...
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Brent Toderian
2 months ago
“Dutch people cycle an average of 2.6km each per day. If this pattern was replicated worldwide, annual carbon emissions would drop by 686 million tonnes. This mammoth figure exceeds the entire carbon footprint of most countries, including the UK, Canada, Saudi Arabia and Australia.”
@euronews.com
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Cycling like the Dutch would slash the world’s carbon footprint
If everybody cycled like the Dutch, we could offset the UK or Australia’s entire carbon footprint.
https://www.euronews.com/green/2023/06/03/on-your-bike-if-we-all-cycled-like-the-dutch-global-emissions-drop-nearly-700-million-tonn
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Rosana Collepardo
2 months ago
Our Science paper is out! Huge congratulations to
@huabin-zhou.bsky.social
, Mike Rosen, and the brilliant
@janhuemar.bsky.social
@juliamaristany.bsky.social
and
@kieran-russell.bsky.social
from our group News:
bit.ly/4avnkAr
and
bit.ly/3XBGVHS
Great perspective by
@vram142.bsky.social
+K Zhang
add a skeleton here at some point
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Ologies with Alie Ward
2 months ago
WE GOT FERNS, folks. I hope you like ferns. If you don’t, just listen and you will like ferns. 🌿🌿🌿 Dr. Li is hilarious and charming and you will love him. And ferns. In conclusion: ferns.
www.alieward.com/ologies/pter...
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Pteridology (FERNS) with Dr. Fay-Wei Li — alie ward
Fronds. Forest dwellers. Spores. Houseplants. Queer icons. We’ve got ferns. The charming and hilarious professor and author of “Ferns: Lessons in Survival from Earth’s Most Adaptable Plants,” Dr. Fay-...
https://www.alieward.com/ologies/pteridology
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Zohran Kwame Mamdani
3 months ago
In the richest city in the richest country on the planet, the thing we can’t afford is to forget those who are left hungry.
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Juliet Turner
3 months ago
POV: you are a young woman celebrating a recent academic success
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It is pathetic to see Cornell shrink from one of its foundational principles
www.cornellsun.com/article/2025...
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FOSTER | "Any Person, Any Study," — If You Can Keep It
In our guest room, Professor of Computer Science Nate Foster reflects on Cornell’s recent settlement with the Trump administration — a deal he argues trades principle for expedience.
https://www.cornellsun.com/article/2025/11/foster-any-person-any-study-if-you-can-keep-it
3 months ago
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Comprehensive sampling of mitochondrial genomes substantiates the Neoproterozoic origin of land plants
This study presents phylogenetic analyses based on565 mitochondrial genomes spanning all major green plant lineages, identifying hornworts as sister to tracheophytes and Charophyceae as sister to land...
https://www.cell.com/plant-communications/fulltext/S2590-3462(25)00259-7
3 months ago
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GeWilli
over 1 year ago
Sphagnum moss Imaged live on the FV4000, a new, paradigm shifting, laser scanning confocal microscope from Evident LifeScience (aka Olympus). Green is from the Hyaline Cells and the red from the [chloroplasts in the] Chlorophyllose cells
#sciart
#microscopes
#moss
(scale noted in the Alt-text)
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Tanmay Bharat
3 months ago
An Asgard archaeon with internal membrane compartments Brilliant study led by
@fmacleod.bsky.social
and Andriko von KĂĽgelgen. Tight collaboration with
@buzzbaum.bsky.social
and lab. Congrats to all authors!
www.biorxiv.org/content/10.1...
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leon
3 months ago
it’s not enough. i challenge andrew cuomo to a 1v1 in super smash bros. i need to watch him lose something a third time
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Ivan Radin
4 months ago
Here are some “leaf” or phyllid cells from moss Physcomitrium patens gametophore. Cells are expressing a green fluorescence marker that labels the vacuolar membrane. Chloroplasts' autofluorescence is in magenta. Can you spot dividing chloroplasts?
#microscopymonday
#moss
#plantcells
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TrustedReveler
4 months ago
LA: we will fight you. Chicago: we will fight you. PDX: we will make you endure week after week of of improv theater.
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Ben Long
5 months ago
We really enjoyed putting together this Darwin Review for JXB. Fun to think about how carboxysomes work and why plants don't have them.
@jxbotany.bsky.social
Function, Evolution, and Future of Carboxysomes url:
academic.oup.com/jxb/article-...
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The Function, Evolution, and Future of Carboxysomes
Abstract. Since their discovery as rubisco-containing compartments more than 50 years ago, significant breakthroughs have advanced our understanding of car
https://academic.oup.com/jxb/article-abstract/doi/10.1093/jxb/eraf425/8266333
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Tim Krief
5 months ago
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Qing (Andie) Zhang
5 months ago
Did you know tiny algae can "skate" within Arctic sea ice? ⛸️ Our new study in
@pnas.org
reveals the secret life of ice diatoms: they are actively gliding to navigate the ice! This adds a new dimension to the sea ice ecosystem, revealing an active, dynamic ecological niche.
@prakashlab.bsky.social
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