We are hiring! Are you an ambitious postdoc with a background in vascular bioengineering and cell biology? Then please join our team at Amsterdam UMC and help unravel the mechanisms that govern vascular integrity. #embobuildnetworks #vascularbiology #EVBO werkenbij.amsterdamumc.org/en/vacatures...

Your budget quantifies your values.

Whenever I give department seminars, I try to make time to visit the uni library. The library is the heart of the university. The books and our monuments to them will outlast both us and the internet - if we preserve them. I haven’t visited MIT, but this feels like a death.

It's time to rewrite reviews-aKG doesn't just regulate demethylation. Work from my lab and @mzspectrum.bsky.social demonstrates a new role for aKG in promoting histone acetylation and DNA repair through regulating carnitine synthesis. Congrats Apoorva Uboveja! www.nature.com/articles/s41...

He warned us we'd have to remind you. "Particularly in times of international conflict, when the dominant definition of the situation is such as to emphasize national loyalties, the man of science is subjected to conflicting imperatives of scientific universalism and ethnocentric particularism."

“then it’s nothing for you to do but enjoy the few minutes you got left the best way you can-by killing somebody or burning down his house or doing some other meanness to him. No pleasure but meanness.” -Flannery www.nytimes.com/2026/05/22/u...

This was fitting news to receive on May 1, international workers day. I will be returning to work on Monday after being kept on retaliatory administrative leave for 5 months and 3 weeks. I return along with the brave Katrina Declaration signers from FEMA, also reinstated this week. 🧵1/?

Creative and elegant work - and well-told @deeparajan.bsky.social @wallaceucsf.bsky.social

just got knocked over by this new paper from the Andrei Chagin lab: www.science.org/doi/epdf/10.... physically dropped the paper in delighted surprise when I got to the second half of Fig 5:

We’re hiring! Tenure-track faculty position in cancer research at LSU Health Shreveport (Pathology & Translational Pathobiology). Looking for investigators building programs at the interface of cancer, metabolism, inflammation, and vascular biology. www.lsuhsc.edu/shv/CareerOp...

Whole organism 3D mapping reveals universal branching topology and biophysical optimization governs vascular and nervous system development Read about our work here: www.biorxiv.org/content/10.6...

📣 New preprint alert! Co-authored by @spalaciosm.bsky.social and @andreacaldarola.bsky.social : Quantitative imaging of calcium dynamics with a green fluorescent biosensor and fluorescence lifetime imaging www.biorxiv.org/content/10.6...

Happy Easter! He is risen!

JBMR® Plus is accepting applications for editor‑in‑chief. Current EIC Deborah Veis, MD, PhD, calls the role one of the most impactful of her career. This paid position's term begins October 2026. Apply by April 3. www.surveymonkey.com/r/8FM2GFJ?ut... Learn More: www.asbmr.org/publications...

Amazing opportunity to work with Kim, who is the most creative scientist and an amazing mentor

Impossible to overstate how timely the @orssociety.bsky.social meeting feels, again, this year. Cannot wait to see dear friends and hear exciting science. Keep an eye out for these amazing scientists at #ORS2026 this week: @cpane94.bsky.social @gkotsaris90.bsky.social @eseidlscience.bsky.social

Introducing the #ORS2026 Spotlight Speakers! We are excited to welcome thesee internationally recognized experts, March 27–31, in Charlotte, NC, sharing insights across mechanobiology, regeneration, data-driven #orthopaedics, and more. 🔎 Learn more: https://www.ors.org/2026spotlightspeakers/

Congratulations to ISFR members @gkotsaris90.bsky.social and @amitsc.bsky.social for their nominations for the New Investigator Recognition Award! Be sure to add their talks to your schedule at #ORS2026 and catch their exciting work in bone fracture repair! 🦴🩻🔬

🎉 Congrats to our finalists for the ORS Business Innovation Competition at #ORS2026! BIC serves as a springboard for #msk innovation, supporting early-stage ideas as they move from the lab to the marketplace. Learn more about each finalist 👉 https://www.ors.org/2026bic .

5%ile is the new 10%ile and CND is just ND.

In this world, shipmates, sin that pays its way can travel freely, and without a passport; whereas Virtue, if a pauper, is stopped at all frontiers. -Melville

Insight is *never* greater than the level of inquiry. I feel second hand embarrassment every time I hear a serious scientist claim an in vitro system/organoid/“NAM” can answer a question it was never intended to ask.

Without considering the sources of claims, efforts at epistemic vigilance become play-acting. With LLMs, we don't know the sources. Excellent thread from @mjcrockett.bsky.social

if you are writing, and need to decide between making things easier for you or easier for your reader (such as using an acronym or cutting white space to fit in more words), always -always- choose your reader. this tweet is not about AI, but it also is.

Let us call her Misty. Life, regeneration & rebirth - sounds right to me 🦛❤️ #worldhippoday #yaptaz

NEW: Another NIH institute director hasn't been renewed — the director of NIAMS (arthritis, musculoskeletal and skin diseases institute). That leaves a whopping 15 of 27 institutes and centers without a permanent director.

With all their speed forward they may be a step backward in civilization—that is, in spiritual civilization. It may be that they will not add to the beauty of the world, nor to the life of men’s souls. - Booth Tarkington, 1918

Thrilled to share our new bioRxiv preprint led by Eloise Fadial (@efadial.bsky.social) 🥳🎉! Using PRDM16 cKO mice, hiPSC models, scRNA-seq & CUT&RUN, Eloise shows that PRDM16 is a key genetic and epigenetic regulator of knee chondrogenesis and chondrocyte identity. www.biorxiv.org/content/10.6...

I present the most interesting graph ever made. HUMAN ON BICYCLE beats every other living thing. www.scientificamerican.com/article/a-hu...

Our new paper just out! pubs.acs.org/doi/10.1021/...

The NIH has indicated a “leniency” period for implementation of the Common Forms (SciENcv) May 2026: grants.nih.gov/faqs#/common... Note: the “warning” that says your materials are not in compliance is also displayed if you submit using the Common Forms. This warning can be ignored.

Almost forgot my Hagoromo chalk this morning. A true crisis. #BE550

New to ORS? 👋 Join our virtual New Member Orientation on Feb 4, 12–1 PM CT to dive into member benefits, networking opportunities, and more! Hear from a current member on ORS’s impact & join the live Q&A. Register: https://ors.memberclicks.net/nmo020426

To the light at the end.

“You are a slow learner, Winston." "How can I help it? How can I help but see what is in front of my eyes? Two and two are four." "Sometimes, Winston. Sometimes they are five. Sometimes they are three. Sometimes they are all of them at once. You must try harder. It is not easy to become sane.”

The Senate may choose to vote together on the DHS and LHHS bills. Thus, a filibuster on DHS may mean no funding for NIH. What my colleagues are saying: “Shut it down, public health will understand. I’ll work without pay again.” - anonymous NIHer

To my children, Fearing for them Wendell Berry

for the growing good of the world is partly dependent on unhistoric acts; and that things are not so ill with you and me as they might have been, is half owing to the number who lived faithfully a hidden life, and rest in unvisited tombs. -Eliot

DH Lawrence, quoted in Robert Stone's introduction to Oakley Hall’s Warlock. America has never stopped being Warlock.

writing is iterative. it pulls out your heart and stomps on it until eventually you wrestle it to the ground, just in time to put your heart back in and fall in bed sick for a week.

This is what you get if you search "opto-YAP" on google scholar. ✨Alternative Approaches✨

First day of class! #BE550

There aren’t many gifts better than having your work written about by someone you admire. Many thanks to @elizelzer.bsky.social for this clear and generous summary of our paper: www.pnas.org/doi/10.1073/...

NIAMS leadership out there fighting the good fight ❤️

As we usher in the new year, we also wanted to celebrate the achievements of a giant in the hashtag#osteoarthritis community. Read more about Frank's legacy and the Frank Beier Graduate Opportunity Scholarship in this month's issue here: www.oarsijournal.com/article/S106...

Defending PhD student, looking over their thesis: “If I knew then what I know now, I could’ve done all of this in like 9 months.” A thread about my favorite pioneering cave explorers and why I don’t think AI will ever “solve” biology.

“You should consolidate your grant down to two aims” is my grant advice superpower. It’s amazing how often it works.

If you are submitting an NIH grant in February, you will be required to use SciENcv to prepare you biosketch. IT IS MUCH WORSE THAN YOU CAN POSSIBLY IMAGINE. Set aside *at least* 4 hours just to transfer an existing an biosketch into SciENcv.

I cannot get over how dysfunctional the now-required sciencv system is. It’s agonizingly slow, filled with errors, kicks you out repeatedly, and fails to save anything. The current NIH in microcosm.