this is a fascinating article, featuring a ton of analytical chemists arguing with one another #chemchat

Anybody got an example of substrate channeling where an isotopic label in a specific product is more enriched than the tracer? I know this is theoretically possible with compartmentalized pools but I am drawing a big old blank on relevant literature?

Found out my well scored MIRA will not be funded, as I am MPI on too many grants. Not close to the direct cost cap at all, but the optics of 5 projects look bad. I understand that and really hope the grant ends up keeping someone else’s lab open. But man it hurts.

We’re hiring a #postdoc! The Dibble Lab at Harvard Medical School and Beth Israel Deaconess Medical Center in Boston studies the regulatory relationship between #signaling and #metabolic pathways. Email me at [email protected] !

Now online in Cancer Discovery: Prenatal Exposure to Chemotherapy Increases the Mutation Burden in Human Neonatal Hematopoietic Stem Cells - by Ilana Struys, Carolina Velázque,z @JoskeUbels, Liesbeth Lenaerts, Ruben van Boxtel, Frédéric Amant, and colleagues doi.org/10.1158/2159...

Call your legislative reps but at this point call your Fisher Sci Reps too.

Happy New Year. I’m pleased to report publication of the Ducker lab’s latest cancer metabolism paper led by graduate student Kyle Dunlap in @cp-cellreports.bsky.social www.cell.com/cell-reports.... 1/n

In back to back thesis committee meetings 4/8 professors had daycare age children. All of us had coughs from being sick recently. ‘Tis the season.

At the end of the day, she said, “I can’t believe they pay you just to go to meetings all day.” She thought for a minute and said, “I guess they would have to pay you.” Boy, did I feel seen. 52/n

Mass spec continues its relentless world takeover:

New preprint alert! First authors Drs. Naveen Tangudu and Raquel Buj used both CRISPR screens and pharmacological approaches to identify novel metabolic vulnerabilities of cancers with p16 loss. Should we re-think anti-metabolites in this context? 🧪 www.biorxiv.org/content/10.1...

Having a 301 area code phone number is like a cheat code at getting professors to call you back. They all think I’m the NIH 😂🥸😂

System Collapse, the next novel in the Murderbot Diaries, is coming out November 14 from @tordotcompub.bsky.social . It's set directly after Network Effect. Cover art is by Jaime Jones.