Toward development of soil-derived Bacillus isolates as lung cancer cytotoxic agents -in BioDesign Research from Tal Danino www.sciencedirect.com/science/arti...

A step forward in discovering Buchnera's key to the aphid's heart, published today! Thanks to Jerry Maeda and other authors--a great team -- and to the helpful reviewers #SymbioSky doi: doi.org/10.1038/s415...

A human-derived peptide eradicated biofilms in preclinical tests, including against ESKAPE pathogens where almost no antibiotic works. It was effective both topically and by injection. doi.org/hb8xmc

🦠💊 A combination #therapy strategy may help slow the rise of global #AntimicrobialResistance by improving the effectiveness of existing #antibiotics. #AMR #Microbiology #Bacteria #PublicHealth #Infection via @sciencex.bsky.social

#microsky #phagesky #phage www.nature.com/articles/s41...

✨ New paper alert: A family of archaeal hibernation factors that bind in tandem and protect ribosomes in dormant cells, Nature Communications (www.nature.com/articles/s41...) Congratulations Amos, @kshulgina.bsky.social, Roan, and @jhdcate.bsky.social! #NSFFunded

JB Editor's Choice: Lee, Giner & Welander identify an enzyme responsible for an unusual 8(14)-unsaturation found in the sterols made by methanotrophs, dinoflagellates, nematodes, and marine sponges - uncovering novel sterol biochemistry. journals.asm.org/doi/full/10.... @asm.org #JBacteriol

#MicroSky: From Antarctica comes a new discovery by Kralova et al doi.org/10.1111/1751.... They identified kineochelins, an unknown group of siderophores produced by rare actinomycetes. A new step toward uncovering new bioactive compounds and antimicrobials.

A novel reverse lipase toxin substrate of the Staphylococcus aureus type VII secretion system www.biorxiv.org/content/10.6...

Another chapter of my thesis is out! We asked whether we could pair proteome-wide AlphaFold screening with Tn-seq to identify biologically relevant protein-protein interactions. We identify ClcR (formerly YerH) as a component of the Rod complex in Gram-positive bacteria. www.pnas.org/doi/10.1073/...

#Tuberculosis bacilli grow more slowly during adaptation to acidic environments. @breealdridge.bsky.social &co use single-cell imaging to show that the bacilli bifurcate into growing & growth-arrested subpopulations, conferring differential #antibiotic responses @plosbiology.org 🧪 plos.io/4vlOhOF

Happy that this is out! Pyocyanin produced by Pseudomonas aeruginosa promotes antibiotic resistance evolution in enterococci.

This is an awesome review from @sheppardlab.bsky.social - Epistasis and co-adaptation in bacterial genome #evolution www.nature.com/articles/s41...

The DdmDE defense system eradicates plasmids by target-centered bidirectional ssDNA loop extrusion and site-specific cleavage

Out Now! Deep learning reveals antimicrobial peptides within prions #MicroSky

Out Now! A phage takes the wheel #MicroSky

Evolved phage cocktails outsmart biofilm defences | Nature Microbiology https://www.nature.com/articles/s41564-026-02401-8

The @nejm.org is very clear - proposed OMB changes to federal funding of research grants would be very bad for science and public health. dx.doi.org/10.1056/NEJM...

Be sure to read this review in our latest issue from Xianzhong Chen et al. at Jiangnan University summarising the engineering strategies applied for the biosynthesis of L-tyrosine and its derivatives in microbial cell factories #natprod #secmet Find it in full here🔽

journals.plos.org/plosbiology/... #microsky

To Move or Not to Move: When and How Bacteria Suppress Flagellar Motility onlinelibrary.wiley.com/doi/full/10.... #MicroSky

Molecular Microbiology | Microbiology Journal | Wiley Online Library https://onlinelibrary.wiley.com/doi/10.1111/mmi.70085?af=R

CapK is a bacterial DNA damage-activated kinase that phosphorylates transcriptional repressor CapS to control adjacently-encoded anti-phage immune pathway genes in response to a universal stress signal, DNA damage @kevincorbett.bsky.social and colleagues link.springer.com/article/10.1...

Bacterial cell division protein FtsZ complexes with a phage protein to activate bacterial immunity @natmicrobiol.nature.com from Michael Laub & Abel Garcia-Pino www.nature.com/articles/s41...

Our paper on the YprA family of helicases and their roles in bacterial defence is now out! We describe ARMADA, a defence system synergise with Druantia and show that both systems spread horizontally on a novel type of mobile genetic element that we call SPIDERs www.sciencedirect.com/science/arti...

www.nature.com/articles/s41... #microsky

Our paper "Gene ancestries reveal diverse microbial associations during eukaryogenesis.” is finally out in Nature. Eukaryogenesis was likely a gradual process shaped by multiple microbial partners and virus-mediated gene transfer, rather than a single binary symbiosis. doi.org/10.1038/s415...

Cascading recombinase memory switch for programmable and stable gene expression in Pseudomonas putida by Javier Hernández @labnikel.bsky.social #SyntheticBiology #MetabolicEngineering #GeneticCircuit #OpenAccess academic.oup.com/nar/article/... @narjournal.bsky.social

#Biofilm matrices containing filamentous phages help #Pseudomonas aeruginosa tolerate antibiotics. @abultarafder.bsky.social @tbharat-lab.bsky.social &co show that #nanobody disruption of #phage Pf4 #LiquidCrystalline droplets restores #antibiotic susceptibility @plosbiology.org 🧪 plos.io/4xkd6Mw

Multiplexing antibiotic screening assay in droplet microfluidics #microbiology #antibiotics #microfluidics #MicroSky doi.org/10.1038/s415...

journals.plos.org/plosbiology/... #microbiome

The Iceman's Microbiome... link.springer.com/article/10.1... #microsky

Happily, I agree with every word of this. But then, I suspected I would. Also, I'm interested to find myself set up against Matt Ridley in our judgements. I leave it to you folks to decide who to trust there 😉. www.science.org/doi/10.1126/...