An Asgard archaeon with internal membrane compartments Brilliant study led by @fmacleod.bsky.social and Andriko von Kügelgen. Tight collaboration with @buzzbaum.bsky.social and lab. Congrats to all authors! www.biorxiv.org/content/10.1...

Looking for a PhD? 🚀 MIBTP projects are out lots to explore! 🔬 #Bacteria • #AMR • #Interdisciplinary • FUN! My projects explore how Gram-negative bacteria build and maintain their three-layered cell envelope, using cryo-EM, fluorescence microscopy and biochemistry. warwick.ac.uk/fac/cross_fa...

www.biorxiv.org/content/10.1... Really excited to have our work out in the world. CCHFV has a 450kDa L-Protein, about twice the size of L-Proteins from other segmented RNA viruses. We have used cryoEM and functional assays to begin to understand it this massive multifunctional protein works.

We are looking for motivated #postdocs to join the lab! Biochemistry/microbiology/cryo-EM experience? Excited by #cryo-EM/ET, #chromatin? ❄️🧬🧫 Interdisciplinary projects, top EMBL facilities! Email CV + short cover letter → [email protected] Info about the group: www.embl.org/groups/dodon...

EMBL’s 2025 Kendrew alumni award recipient may know how to make fairy tales come true. Irma Querques (@irmaquerques.bsky.social) repurposed the ‘Sleeping Beauty’ transposon as a genetic tool for new therapeutics, particularly against cancer. www.embl.org/news/people-...

Independent research fellowships leading to tenured positions at the John Innes Centre. Repost = nice. Thank you very much!!!

Our PhD studentship programme is officially open; pass it on If you are looking for a fully-funded PhD in the mechanisms underlying human disease, here are the details... Great science and a great environment! www.path.ox.ac.uk/news-article...

Together with colleagues at the Dept. of Microsystems Engineering, we are looking for a PhD student to develop methods for femtoliter-scale sample dispensing in cryoEM sample preparation. edu.nl/h436k If you like interdisciplinary research & fascinating physics at ultrasmall scales, please apply!

Excited to share our latest work, driven by my recently graduated PhD student Kaitlyn Barrack, exploring the mechanisms of bacterial dysbiosis in the CF gut - including a role for a colorectal cancer-associated genotoxin in this competition. www.biorxiv.org/content/10.1... @kbarrack.bsky.social

Sub-cellular chemical mapping in bacteria using correlated cryogenic electron and mass spectrometry imaging Congrats Hannah Ochner and authors on this important paper! Strong collaboration with @kiranrpatil.bsky.social www.biorxiv.org/cgi/content/... @mrclmb.bsky.social @wellcometrust.bsky.social

Our newest manuscript on the gut-lung axis in CF, lead by Rebecca Valls, explores sex and intestinal regional differences in response to Bacteroides. Check it out! www.biorxiv.org/content/10.1...

We are excited to be a part of a collaboration lead by Tarafder and Bharat titled "Targeted disruption of phage liquid crystalline droplets abolishes antibiotic tolerance of bacterial biofilms" - this work has exciting implications for biofilm-targeted therapeutics. www.biorxiv.org/content/10.1...

Targeted disruption of phage liquid crystalline droplets abolishes antibiotic tolerance of bacterial biofilms led by @abultarafder.bsky.social Great collaboration with @pearce-maths.bsky.social and @geiselbiofilm.bsky.social www.biorxiv.org/cgi/content/...

Highly collaborative efforts that involved 6 lab members and the labs of @yiliangding.bsky.social and @rdaslab.bsky.social. We uncovered a telomerase dimer and its potential role in telomere maintenance.

Exciting study from @kiranrpatil.bsky.social and colleagues. Hannah Ochner from the group performed cryo FIB imaging. Congrats!

Excited to share our latest review on histone-mediated chromatin organization in prokaryotes and viruses! 🧬 @mpi-bio-fml.bsky.social

Bedaquiline resistance driven by the MmpS5L5 efflux pump is threatening the drug regimens used to treat MDR-TB. In our new preprint, we used structural and genetic approaches to better understand how MmpS5L5 effluxes bedaquiline and how future resistance may evolve. 🧵🔽 #TBsky #MicroSky #TB

Excellent opportunity for a postdoc to join @jgreener64.bsky.social’s group at the LMB. You’ll help develop novel molecular simulation methods to optimise sequences for diverse design tasks in computational protein design. See: www.nature.com/naturecareer... Apply by 13 JUL #PostdocJobs #ScienceJobs

We have a 3-year funded postdoc position to work on structures of #amyloid filaments. If you are an expert in protein biochemistry, structural biology or #cryoEM / #cryoET, this could be for you! Feel free to email me with any questions. Come join us! 🤩 www.nature.com/naturecareer...

Structural and functional analysis of the Mycobacterium tuberculosis MmpS5L5 efflux pump presages a pathway to increased bedaquiline resistance Exciting paper by Adam Fountain and Lalita Ramakrishnan. Cryo-ET by @janboehning.bsky.social Congrats! www.biorxiv.org/content/10.1...

The mechanics of a continuous self-assembling surface-layer aids cell division in an archaeon out in @pnas.org Tight collaboration with Sherman Foo, Alice Cezanne and @buzzbaum.bsky.social, Sulfolobus cryo-ET from @idocaspy.bsky.social www.pnas.org/doi/10.1073/...

Structure of the virulence-associated Neisseria meningitidis filamentous bacteriophage MDAphi Out in @pnas.org Congrats @janboehning.bsky.social @abultarafder.bsky.social Miles Graham @mathieucoureuil.bsky.social @mrclmb.bsky.social @hopitalnecker.bsky.social www.pnas.org/doi/10.1073/...

Congratulations to @tbharat-lab.bsky.social, Group Leader in the LMB’s Structural Studies Division, who has received the Gold Medal from @embo.org for his research on prokaryotic surface molecules. Read more here: www2.mrc-lmb.cam.ac.uk/tanmay-bhara... #LMBNews

Excited to share our new preprint on HLp—a bacterial histone from Leptospira perolatii that forms stable tetramers and wraps ~60 bp of DNA: "DNA Wrapping by a Tetrameric Bacterial Histone" www.biorxiv.org/content/10.1... @mpi-bio-fml.bsky.social

Latest news from Dept of Protein Evolution. This preprint reveals the first structurally detailed look at how a bacterial histone wraps DNA, offering new insights into genome organization in bacteria. Check it out: shorturl.at/GTIpA Findings & author info in @vikramalva.bsky.social thread below.

Exciting job opportunities! Two postdoc positions are available in the Fodor Lab at @dunnschool.bsky.social to study influenza virus transcription, genome replication, nuclear export and assembly. More info: my.corehr.com/pls/uoxrecru...

Finally in peer-reviewed form: Mapping the ultrastructural topology of the corynebacterial cell surface. @bupbuse.bsky.social @vikramalva.bsky.social Please also see concurrent beautiful work from @adriasogues.bsky.social and Han Remaut.

A colder frontier in cryo-EM 🧪🔬 Chris Russo’s group, inc. Joshua Dickerson, adapted #cryoEM to work at liquid helium temperatures (13 kelvins), where every frame captured contains more information than the equivalent using liquid nitrogen (81 kelvins). Read more: tinyurl.com/mwwcunkc #LMBResearch

The unique #CellEnvelope of #corynebacteria: @tbharat-lab.bsky.social &co map the C. glutamicum cell surface, revealing a patchy S-layer & specific assembly of the PS2 protein, thereby informing our understanding of cell envelopes that contain #MycolicAcids @plosbiology.org 🧪 plos.io/3Y6JNgw

We are looking for a postdoctoral fellow to join us to explore telomerase regulation by histones. Please get in touch if this may interest you.

We are thrilled to announce the 2025 EMBO practical course in cryo-em image processing, Birkbeck College, London, 9-16 Sept 2025. More info & apply: meetings.embo.org/event/25-cry... Organisers Giulia Zanetti & Helen Saibil. Beautiful image from co-organizer @carolynmoores1.bsky.social lab.

Great opportunity in a fantastic lab

We are looking for a Senior Administrator to join our Structural Studies Division, to provide proactive assistance to the Heads of Division & efficiently manage all aspects of administration to support our researchers. More info: www.jobs.ac.uk/job/DLY086/s... Closes 19 MAR #AdminJobs #CambridgeJobs

If you're looking to do a PhD in bioinorganic and medicinal chemistry in a wonderful research group at a world-leading institute, here's a great opportunity: www.crick.ac.uk/careers-stud... @jeanninehess.bsky.social

Structural biology inside multicellular specimens using electron cryotomography by @idocaspy.bsky.social @zhexinwang.bsky.social out now in Quarterly Reviews of Biophysics doi.org/10.1017/S003...

@tbharat-lab.bsky.social on Multi-scale, correlated imaging to study principles of bacterial biofilm formation #MultiBac2025

We have an opening for a 4 yr PhD interested in membrane remodelling and cryo-EM/ET of a minimal cell division machinery: edu.nl/bukan You will be part of the EVOLF consortium in which 30 leading biochemists/biophysicists work together to explore if and how we can build autonomous synthetic cells.

You or someone you know interested in cell envelopes and getting a PhD? Come join me warwick.ac.uk/fac/cross_fa... or have a look at some of the other fantastic projects on offer @uni-of-warwick.bsky.social

First last author paper FINALLY out today. Thank you to all the authors for their hard work ☺️

Are you looking for an exciting postdoc opportunity? EMBL EIPOD fellowship call is open! If you are passionate about chromatin and cryo-EM, and are motivated to learn and use other methods as well, and be involved in a collaborative project - Get in touch! #postdoc #EMBL www.embl.org/about/info/p...

If you’re interested in how molecular motors coordinate to power intracellular trafficking events (e.g. endocytosis), I’ve got a PhD position available to study this at vibrant Bristol uni. In this project, we will capture highly dynamic events by #cryoEM, single molecule imaging & cell biology. 🔬❄️🧪

For those who missed it: Elon Musk, the Royal Society, and me deevybee.blogspot.com/2024/11/why-...

Join EMBL’s scientific community 🙌 Apply until 31 December: 👉 EMBL CPP fellowship www.embl.org/about/info/s... 👉 EMBL Sabbatical Visitor fellowship www.embl.org/about/info/s... We can’t wait to see you around! 🧪🧬 🔬 🖥️ #MolBiol

I am about to be recruiting two post-docs to work on cryoEM and cryoET of amyloid aggregates... Anyone interested please drop me a line while the wheels of our HR department turn.............

Really looking forward to welcoming & meeting the participants of our #EMBOStructBio course this morning! Many of our speakers/tutors are here: @moalquraishi.bsky.social @sykhalid.bsky.social @ezgikaraca.bsky.social @amjjbonvin.bsky.social @gchojnowski.bsky.social @drmelissagraewert.bsky.social

🚨 Attention #teamtomo PhD students! 🚨 12-week paid internship opportunity at Genentech. Want to see how we use cryoET in pharma? And spend the summer 2025 in the Bay Area? Details and application link here: roche.wd3.myworkdayjobs.com/ROG-A2O-GENE...

Reposting this, just in case. Our lab is located @iecb.bsky.social on the campus of @univbordeaux.bsky.social

Can I ask you to share a PhD advert at Bristol Uni please? Rhomboid proteases play a role in neurons that is essential for life- but it is not characterised. Got a student interested in cell biology, electrophysiology and neurobiology? Send them our way! tinyurl.com/56f24f7c