Irma Querques
@irmaquerques.bsky.social
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📥 166
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Assistant Prof and Group Leader at Max Perutz Labs, University of Vienna
reposted by
Irma Querques
IMP
26 days ago
Scientists uncovered how the immune protein ZNFX1 enables cells to walk the fine line between fighting infection & avoiding autoimmune damage. ZNFX1 can ubiquitinate & compact host & viral RNA into molecular condensates, extending ubiquitin biology to RNA itself. More:
www.imp.ac.at/news/article...
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ZNFX1 compacts and tags RNA to keep immunity in check
Tim Clausen’s lab at the IMP and collaborators have uncovered how the ancient immune protein ZNFX1 enables cells to walk the fine line between fighting infection and avoiding autoimmune damage. The te...
https://www.imp.ac.at/news/article/znfx1-compacts-and-tags-rna-to-keep-immunity-in-check
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Excited to share my talk at the EMBL John Kendrew Award ceremony about what transposons taught me about science, life, and change along the way. Big thanks to my mentors, the
@embl.org
Alumni community, and my current scientific home
@maxperutzlabs.bsky.social
💛
youtu.be/NwIikKS7EWE?...
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Irma Querques - 2025 John Kendrew Award Recipient
YouTube video by EMBL Alumni
https://youtu.be/NwIikKS7EWE?si=4s4gXnW4QW1RlmCm
28 days ago
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Irma Querques
Luuk Loeff
about 1 month ago
Exciting times ahead! Today marks the first day of the Loeff Lab at Leiden University Medical Center in the Netherlands 🇳🇱. I’m thrilled to begin this new adventure and continue exploring microbial defense mechanisms and their applications through an integrative structural biology approach.
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Irma Querques
Max Perutz Labs Vienna
about 1 month ago
Congrats to group leader
@irmaquerques.bsky.social
on receiving the EMBL's John Kendrew Award! 🎉 From left to right: Irma's former advisor Christoph Müller, Irma, and Pavel Tomancak, Chair of the EMBL Alumni Association. (c)
@embl.org
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Julius Brennecke
about 2 months ago
last call! submit your abstract by tonight to be selected for one of the many oral presentations at the leading European Transposon Meeting. We are very much looking forward to your contribution and attendance!
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Irma Querques
Yan Ma
2 months ago
First Ma lab
#GMI
paper is now online! It‘s a mini-review on insect-induced plant
#galls
—their coolness and research potential! Plant galls induced by insects: Coordinated developmental reprogramming and defence manipulation
www.sciencedirect.com/science/arti...
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Irma Querques
Max Perutz Labs Vienna
2 months ago
The DOC-torate dream team! 🎓 Seven Perutz PhD students just secured
@oeaw.bsky.social
DOC Fellowships - the most we've ever had in one year! Huge Congrats! 🎉➡️
tinyurl.com/29nvtf7j
@univie.ac.at
@meduniwien.ac.at
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Irma Querques
Julius Brennecke
2 months ago
Pls. share widely Calling all transposon fans & lovers of genetic innovation MOBILE GENOME welcomes you in Heidelberg, Nov. 4–7 2025 → Vibrant & friendly community → Cutting-edge talks from mechanisms to physiology → Plenty of surprises (TEs never stop innovating) submit abstract by July 29
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Irma Querques
Christa Buecker
2 months ago
My colleagues are awesome!
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Irma Querques
Max Perutz Labs Vienna
3 months ago
📢 Open Call! The Max Perutz Labs invite applications for a Full Professorship in Molecular Mechanisms of Disease. More information ➡️
tinyurl.com/3yn883b8
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Irma Querques
Science Magazine
3 months ago
Exclusive: An international scientific competition widely credited with spurring the development of artificial intelligence for biology appears to be on its deathbed.
scim.ag/44ukS90
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Exclusive: Famed protein structure competition nears end as NIH grant money runs out
Agency silent on funding renewal for contest that inspired creation of AIs that predicted how proteins would fold
https://scim.ag/44ukS90
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Irma Querques
Martin Loose
3 months ago
One of the most exciting discoveries from our lab so far is now online as a preprint! Read a story on how the ParMR and Min systems started to collaborate to create the CorMR cytoskeleton, which now controls cell shape in multicellular cyanobacteria:
www.biorxiv.org/content/10.1...
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Evolutionary repurposing of a DNA segregation machinery into a cytoskeletal system controlling cyanobacterial cell shape
Bacteria, despite their diversity, use conserved cytoskeletal systems for their intracellular organization. In unicellular bacteria, the ParMRC DNA partitioning apparatus is well known for forming act...
https://www.biorxiv.org/content/10.1101/2025.06.27.661541v1
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Irma Querques
Max Perutz Labs Vienna
3 months ago
🌞 A warm welcome to our summer school students! We're excited to have eight bright young scientists joining us at the Perutz for the next few weeks – diving into research, discovery, and lab life. Here's to a summer full of science and inspiration!
@vbcscitraining.bsky.social
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Christa Buecker
3 months ago
Exciting and rare opportunity to join the
@maxperutzlabs.bsky.social
and the
@viennabiocenter.bsky.social
as a Full Professor!
www.nature.com/naturecareer...
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Full Professorship in Molecular Mechanisms of Disease - Vienna BioCenter, Austria job with Max Perutz Labs, University of Vienna | 12841053
Join theMax Perutz Labs as Full Professor to unravel disease mechanisms—from metabolism and stress to RNA regulation, epigenetics, and immunity.
https://www.nature.com/naturecareers/job/12841053/full-professorship-in-molecular-mechanisms-of-disease/?TrackID=26109&BatchID=854&JobAlertId=33612&cmpid=JBE_TL_20250702_jobtitle&utm_source=jbe&utm_medium=email&utm_campaign=JBE_TL_20250702_applynow_job1
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Irma Querques
IMP
3 months ago
Congrats to Clemens Plaschka, who was selected to become a Member of the European Molecular Biology Organization (EMBO
bsky.app/profile/embo...
), becoming the eighth out of 14 IMP faculty members to receive this honour. More on Clemens Plaschka and his research:
www.imp.ac.at/news/article...
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Irma Querques
Giorgia Guglielmi (she/her)
3 months ago
Spoke at
@viennabiocenter.bsky.social
last week about my path from lab bench to newsroom. I talked science journalism (what it is + isn’t), how to talk to journalists, and how to start in
#scicomm
. Thanks to
@irmaquerques.bsky.social
&
@vbcscitraining.bsky.social
for having me!
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Huge congratulations
@sramundo.bsky.social
So well deserved!
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3 months ago
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Irma Querques
Max Perutz Labs Vienna
3 months ago
👏 Alwin Köhler, group leader and scientific director, has received an
@erc.europa.eu
Advanced Grant! His project will explore how nuclear pore complexes remodel nuclear membranes to form functional channels ➡️
tinyurl.com/3wcvexc9
#ERCAdG
@univie.ac.at
@meduniwien.ac.at
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Irma Querques
Vienna BioCenter Scientific Training
4 months ago
What’s it like to be a postdoc at the Vienna BioCenter? Anna Osnato shares her experience from joining the Institute of Molecular Biotechnology. The VIP³ PostDoc Program call is open – apply now for this unique opportunity!
training.vbc.ac.at/post-docs/vi...
#VBCPostDoc
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Irma Querques
Fyodor Urnov
6 months ago
Professional gene editor and professor of Genetics here. The world does not need more negativity. It does not need more nonscientific hype, either. I will be data-based negative and say to Colossal: give me a double-strand break!! [1/3]
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Irma Querques
Nature Biotechnology
6 months ago
Employing engineered split inteins to replace the internal regions of target proteins in a single reaction.
www.science.org/doi/10.1126/...
#NBThighlight
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Protein editing using a coordinated transposition reaction
Protein engineering through the ligation of polypeptide fragments has proven enormously powerful for studying biochemical processes. In general, this strategy necessitates a final protein-folding step...
https://www.science.org/doi/10.1126/science.adq8540
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Irma Querques
Julius Brennecke
6 months ago
We are seeking a new colleague to join us at the Vienna BioCenter, specifically at my beloved home institution, IMBA
@imbavienna.bsky.social
we value collegiality and a passion for curiosity driven science. Being a great and fun human being also helps!
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Irma Querques
Institute of Molecular Biotechnology
6 months ago
IMBA is recruiting a Junior Group Leader! Are you interested in starting your own lab, pursuing curiosity-driven basic research in the life sciences? Apply now to our group leader position. The deadline is May 28. Link is below.
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Very happy to have Iana in our team!
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6 months ago
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Irma Querques
Ezgi Karaca
9 months ago
The legendary EMBO Integrative Modeling Course is back! If you want to be in this picture in the 2025 edition, just go ahead and register at
meetings.embo.org/event/25-bio...
Organized by myself &
@amjjbonvin.bsky.social
&
@arneelof.bsky.social
&
@lindorfflarsen.bsky.social
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Irma Querques
Nature Microbiology
9 months ago
OUT NOW: Evolutionary origins of archaeal and eukaryotic RNA-guided RNA modification in bacterial IS110 transposons by Samuel Sternberg,
@audeber.bsky.social
& co
www.nature.com/articles/s41...
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Evolutionary origins of archaeal and eukaryotic RNA-guided RNA modification in bacterial IS110 transposons - Nature Microbiology
Structural and phylogenetic analyses show that programmable RNA modifications ubiquitous in archaea and eukarya arose from bacterial transposons.
https://www.nature.com/articles/s41564-024-01889-2
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Irma Querques
Luuk Loeff
9 months ago
What a great way to end the year! ✨ Today in
@cellpress.bsky.social
we report the structure and function of the Shedu anti-phage defense system.
tinyurl.com/4crj6dnx
A long 🧵...
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