Meet our new #AllianceFellow Jack Whitehead! The short interview about his work in the @chlandalab.bsky.social and Mahamid lab at @embl.org can be found on our LinkedIn account. @jackwh18.bsky.social

Transient RNA structures play a key role in the emergence of highly pathogenic avian influenza viruses! Great to see this collaboration with Mathis Funk, Mathilde Richard, Stephen Cusack, and others in @science.org www.science.org/doi/10.1126/...

🚨Preprint! Happy to share the research from my PhD “Genome delivery of a contractile tailed phage and its superinfection exclusion mechanism”. We use cryoEM to study the genome ejection of the phage T4, revealing how the tape measure protein regulates the process. www.biorxiv.org/content/10.6...

Mosquitoes like Aedes aegypti spread viruses that cause major global diseases. We decided to have a closer look at a family of mosquito carbohydrate-binding proteins involved in infecting these vector species. We found some unexpected things 😁 Preprint out now 🦟🦟🦟 www.biorxiv.org/content/10.6...

Delighted to hear from Jeremy Keown of @uni-of-warwick.bsky.social, outlining their work through ISIDORe, accessing Instruct-ERIC structural biology technologies! There is still time to join us for the webinar here - instruct-eric.org/events/instr...

I am super happy to share this paper in its final form. We used FIB milling to "dig in to" cell lines and mouse brains infected with tick-borne flaviviruses, followed by cryo-ET to study the virus replication. It's open access, so have a look! #virology #teamtomo www.nature.com/articles/s41...

Cryo-EM structure reveals how influenza A virus NEP binds the viral polymerase at a regulatory hotspot, coordinating RNA synthesis and nuclear export. Fantastic collaboration with @loiccarrique.bsky.social and Jon Grimes. www.science.org/doi/10.1126/...

Beautiful work from @efodor.bsky.social and Jonathan Grimes' labs - the first full structure of the influenza A virus NEP protein, and a clear indication that its role in viral replication is more nuanced that first thought www.science.org/doi/10.1126/...

Open #postdoc fellowship in my group. Virus replication and cryo-ET. Projects can be tailored to ambitious candidates with diverse backgrounds, so don't hold back from applying! DM for more info. Deadline 8 Feb. Apply here: umustipendie.varbi.com/en/what:job/... #virus #virology #teamtomo #cryoEM

Now out in Science Advances: www.science.org/doi/10.1126/...

Very cool to see our Umeå colleague and fellow structural virologist raking in a major grant. Congrats @maxrenner.bsky.social ! www.umu.se/en/news/umea...

If you are looking for a PhD in the UK, please check out the LIDo program - www.lido-dtp.ac.uk/apply. If you are interested in viruses and making genetically edited salmon, please look up my icase project. International students are welcome to apply! Please reach out if you have questions.

Our new preprint is out 🥳🥳🥳 Henipaviruses, like Nipah and Hendra, package their genomes inside helical shells built by thousands of nucleoproteins. These nucleocapsids are essential to protect the viral RNA, but how do they ever let the polymerase in to read the sequence? 👇

Jeremy is an excellent scientist and leader. Highly recommended!

warwick.ac.uk/fac/cross_fa... I am advertising for a PhD position in my group. We'll be investigating how pathogenic RNA viruses replicate in the nucleus. The project will teach cryoEM/ET, virus culture, and in vitro assays. If you're interested reach out and I'd be happy to have a chat.

Looking for a PhD? 🚀 MIBTP projects are out lots to explore! 🔬 #Bacteria • #AMR • #Interdisciplinary • FUN! My projects explore how Gram-negative bacteria build and maintain their three-layered cell envelope, using cryo-EM, fluorescence microscopy and biochemistry. warwick.ac.uk/fac/cross_fa...

Visualizing influenza A virus assembly by in situ cryo-electron tomography www.nature.com/articles/s41...

www.biorxiv.org/content/10.1... Really excited to have our work out in the world. CCHFV has a 450kDa L-Protein, about twice the size of L-Proteins from other segmented RNA viruses. We have used cryoEM and functional assays to begin to understand it this massive multifunctional protein works.

Postdoc opportunity in another group in my department:

Register now for this fantastic, friendly and affordable influenza community meeting - hope to see you there! Please spread the word 😊

REGISTRATION NOW OPEN Influenza Update 2025 University of Warwick, 15th - 16th December warwick.ac.uk/fac/sci/med/... Registration from £50 - £120 DEADLINE: 7th November We hope you can join us there!

I am very excited to share our preprint: ‘Divergent antibody-mediated population immunity to H5, H7 and H9 subtype potential pandemic influenza viruses’. The first authors are Lucas Benjamin Stolle, Jai Bolton, Rebecca Steventon & Reanna Gregory. lnkd.in/eeYmfvdE

Dear scientific community, I am looking for two postdoctoral structural biologists to join my group at the Department of Biochemistry, University of Oxford. my.corehr.com/pls/uoxrecru... my.corehr.com/pls/uoxrecru...

Very pleased to have our new work out where we perform a structure/function study on the bornavirus polymerase complex with fantastic coauthors. Have a read www.nature.com/articles/s41... @warwicklifesci.bsky.social @loiccarrique.bsky.social @franziskaguenl.bsky.social

Excited to share our work describing a series of structures that allow us to propose a new model for Hantavirus genome replication by the viral L-protein. Another great experience with @loiccarrique.bsky.social @ben-nilsson-payant.bsky.social @efodor.bsky.social Jon Grimes. doi.org/10.1371/jour...