And the sister paper from collaborator and good friend Katie Doores ... A deeper dive into how some of these broadly neutralising #sarbecovirus #coronavirus #sars2 #covid antibodies actually work www.biorxiv.org/content/10.1...

Our first post on here and it's a doozy 😍🤩. Our epic piece on #sarbecovirus host range. #virology #sars2 #covid #vaccines. Enjoy and please repost. www.biorxiv.org/content/10.1...

Really excited to have been a small part of this work investigating sarbecovirus host range, receptor usage and antigenicity! www.biorxiv.org/content/10.1101/2025.09.03.673949v1

In new study led by @ckikawa.bsky.social, we provide near real-time data on human neutralizing antibody landscape to influenza by measuring ~26,000 titers to >100 recent viral strains Data can inform vaccine selection & evolutionary/epidemiological modeling www.biorxiv.org/content/10.1...

New preprint! If some merbecoviruses use DPP4 and others use ACE2, what do those hedgehog merbecoviruses use?! As it turns out, neither! In our latest study, we uncover the "missing" receptor for the MERS-related viruses in hedgehogs. [These findings were first shared at ASV this year] (1/6)

The cow udder may be a mixing vessel where different strains of influenza can recombine--"underscoring its potential role in generating novel influenza viruses with pandemic risk." [Preprint] www.biorxiv.org/content/10.1...

Finally!

Really excited to have been a part of this study, lead by @willharv.bsky.social on how reassortment of H5N1 in birds has lead to a 'specialist' genotype that thrives in seabirds and drives summer/spring (rather than winter) waves of poultry outbreaks www.biorxiv.org/content/10.1...

Come work with us👇

Very pleased to have our new work out where we perform a structure/function study on the bornavirus polymerase complex with fantastic coauthors. Have a read www.nature.com/articles/s41... @warwicklifesci.bsky.social @loiccarrique.bsky.social @franziskaguenl.bsky.social

🚨 New paper alert! 🚨 Here we show that stabilized influenza hemagglutinin HPAI H5 immunogens improve the quality of elicited antibody responses. Thank you to @open_phil for funding this work! bit.ly/4lgr0rM

Exciting new work from my @ciddpsu.bsky.social colleagues showing that pandemic H1N1 immunity reduces susceptibility to H5N1 infection and disease in ferrets.

🦇 NEW RESEARCH: Our 3-year study of Australian flying foxes identified six co-circulating coronaviruses, with highest rates of infection and co-infection in young bats, and evidence of circulating recombinants 🧪🌏 🧵 Available open access in @natcomms.nature.com 📄 www.nature.com/articles/s41...

Very happy that our paper on the receptor binding properties of contemporary H3N2 viruses is now published @CellReports # glycotime www.cell.com/cell-reports...

This is quite late but our lab has a preprint out about a SARS-CoV-2 situation we had in mink in Lithuania back in 2021. It's a doozy with re-emergence of extinct lineages, a country-wide test of all mink farms in Lithuania & some interesting dynamics in mink. www.medrxiv.org/content/10.1... 1/5🧵

A hybrid coronavirus, formed of cat and dog coronaviruses, caused a severe outbreak of disease among cats in Cyprus, researchers found. Their work, in Nature, showed how this new virus was able to cause widespread cases of Feline Infectious Peritonitis (FIP) among the island’s cats.

I am paw-sitively thrilled to say that out latest work is out in Nature today! #Virology #Genomics #Coronavirus #AnimalHealth #InfectiousDisease #Sequencing #FIP #FCoV23 www.nature.com/articles/s41...

Our paper describing how in-host evolution of a recently emerged, highly pathogenic coronavirus modulates entry into cells, membrane fusion and likely pathogenicity has now been published in its peer-reviewed form! Led by Ale Tortorici! @hhmi.org www.nature.com/articles/s41...

New job offer in the team! If you're an experienced virologist (with a PhD), join us to work on Horizon Europe-funded APPEAL project in the vibrant city of Montpellier, South of France! euraxess.ec.europa.eu/jobs/359640

Rare postdoc opportunity to study the emergence and evolution of pandemic viruses in the lab of Dr. Martha Nelson in the Division of Intramural Research (DIR) at the National Library of Medicine (NLM). www.training.nih.gov/jobs/pdf-cb-...

Our new paper on SARS-CoV-2 furin cleavage site is now out at JVI. Study examines disruption (rather than deletion) of the FCS & maintains the longer S1/S2 loop found in #SARS2. FCS disruption attenuates pathogenesis, but not required (but helps) transmission. journals.asm.org/doi/10.1128/...

Excited to present the first review from my lab! Which mutations allow H5 influenza to jump into humans or other mammals? How close is H5 to a pandemic? This review has the answers and explains the molecular mechanism behind the mutations. Led by @fcapelastegui.bsky.social. doi.org/10.1099/jgv....

SAVE THE DATE! The 2025 Influenza Update Meeting will be held ‪@uni-of-warwick.bsky.social on the 15th and 16th December - ‪@nicolerobb.bsky.social‬ is leading the organisation for this year's event. We hope you'll join us there - please repost! www.gla.ac.uk/research/az/...

🚨🔎 Out now in PLOS Pathogens ! 🔎🚨 This project has taken us @cvrinfo.bsky.social @uofgmvls.bsky.social on a wild and wonderful journey. I am excited to share our story of how influenza A viruses (IAVs) exploit cell death to facilitate its covert spread. N/1 journals.plos.org/plospathogen...

JOB: Our Viral Gene Expression research group is looking for a Postdoctoral Researcher to join a project examining virus-host interactions between arboviruses and their mosquito vector. Full details and to apply ➡️ www.pirbright.ac.uk/careers-and-...

If you don't pasteurise it, how long can H5N1 influenza viruses stay infectious for in milk? We had a look at this in a new preprint with ‪@cvrinfo.bsky.social‬, @roslininstitute.bsky.social‬, ‪@pirbrightinst.bsky.social‬ & the APHA (1/N) www.medrxiv.org/content/10.1...

Our study screening the majority of all published Merbecovirus RBD’s for cell entry phenotypes is now published in Nature Communications! (1/5) shorturl.at/gYz4E

A long thread about mpox and the context specific nature of outbreaks prompted by the large outbreak of MPXV Clade IIb happening at the moment in Sierra Leone:

Great opportunity to work on influenza virus-host factor interactions in a brand new lab at Imperial (led by a friend and collaborator, Carol Sheppard) www.imperial.ac.uk/jobs/search-...

Absolutely thrilled to announce the launch of ARTIC2 - a £5.5M 5 year project funded by @wellcometrust.bsky.social to build on the ARTIC approach of low-cost, globally accessible genome sequencing for surveillance of outbreaks, epidemics and endemic diseases: www.birmingham.ac.uk/news/2025/am...

A new review on H5 'bird flu' is just out in @natrevmicro.nature.com: "Evolution, spread & impact of highly pathogenic H5 avian influenza A viruses" by Beatriz Bellido-Martin, Willemijn Rijnink, Matteo Iervolino, Thijs Kuiken, Mathilde Richard & Ron Fouchier, from @erasmusmc.bsky.social. A 🧵 (1/9)

Only 10 days left to apply! 👇 my.corehr.com/pls/uoxrecru...

Sooo happy to finally have this one published!! (3 years in the making… 👀) A comprehensive investigation into the recency and geographical origins of both SARS-CoVs that spilled to humans in the past few decades, now in @cp-cell.bsky.social www.cell.com/cell/fulltex...

🚨We’re hiring a Postdoc to join our group at Oxford! We’re developing methods to understand how pathogens evolve—across hosts, over time, & through molecular & structural change. Keen or know someone who is? Please share! 🕒 3-year post 📅 Deadline: 30 May 🔗 Apply: www.jobs.ox.ac.uk/vacancy/179640

I'm very excited to share the latest work from my group, led by @ahturner934.bsky.social. We revisited one of my favorite proteins (Rab11) and its role in influenza infection& discovered surprising new things. Rab11B is required for entry of current H3N2 isolates! 1/n www.biorxiv.org/content/10.1...

Happy to have this story now published in @PNAS The Q226L mutation can convert a highly pathogenic H5 2.3.4.4e virus to bind human-type receptors | PNAS #glycotime www.pnas.org/doi/10.1073/...

A flu lineage has likely gone extinct since 2020 🧵

I’m delighted that we could contribute the #cryoEM data to this incredible antiviral discovery project from the group of @neytsjohan.bsky.social 💊 "A coronavirus assembly inhibitor that targets the viral membrane protein" www.nature.com/articles/s41... A huge congrats to everyone involved! 🎉

When the US reported a year ago that the H5N1 avian influenza virus had infected dairy cattle, it seemed some rare confluence of factors had allowed the virus to infect the cows’ udders. Then it happened again. And again. Story in @science.org on some questions about the origins of H5N1 in cows… 🧪

One year after the first infections were reported, it's still unclear how highly pathogenic avian influenza virus H5N1 jumped into U.S. cattle—and why it keeps doing so. Science Insider article by @kakape.bsky.social www.science.org/content/arti...

Why can't these viruses be friends? In a new study from her PhD @cvrinfo.bsky.social, #AnnaSims shows that #SARS-CoV-2 infections segregate into distinct microdomains as they spread. But why? (1/N) journals.asm.org/doi/10.1128/...

After 5 years, 150k papers and 17 million genomes, here's what we learned about SARS-CoV-2 and viruses in general. It holds lessons for future pandemics - only if we listen. "We’re in a worse place in terms of pandemic prevention" @eddieholmes.bsky.social told me. www.nature.com/articles/d41...

In study led by @csimonich.bsky.social & Teagan McMahon, we quantify antigenic evolution of RSV F Important because: 1️⃣ RSV top cause of infant hospitalization in USA 2️⃣ New antibodies & vax can prevent hospitalizations 3️⃣ Will virus evolution erode their efficacy? www.biorxiv.org/content/10.1...

A new preprint from our group about the importance of the SARS-CoV-2 spike furin cleavage site (FCS) for pathogenesis and possibly transmission. tinyurl.com/2dya48ky

The epidemiology and evolution of H3N2 canine influenza virus in dogs over 20 years. Lead by @brianrwasik.bsky.social shows that spread is determined by the dog population structure. The virus has not become better at transmitting in dogs after 1000s of transfers. pubmed.ncbi.nlm.nih.gov/40040347/

For something different... Happy to report the accepted version of our manuscript on H3N2 Canine Influenza Virus (CIV) in US dogs over the past 20 years, at Epidemiology & Infection (Cambridge). #influenza #virology www.cambridge.org/core/journal...

Mature #HIV-1 contains >2000 copies of “spacer peptide 2”, but we didn’t know why. We now see that SP2 binds the matrix protein and triggers the change into its mature arrangement. Summary video from @margotriggi.bsky.social

Our analysis of the second incursion of H5N1 viruses (genotype D1.1) into dairy cattle in the US is now posted to virological virological.org/t/timing-and...

1 week left to apply for this!

Core-funded postdoc position at The Pirbright Institute, Surrey, UK (just outside London), in the group of Professor Ian Brown. Working on H5N1 avian influenza virus evolution and development of cross-reactive vaccines. www.pirbright.ac.uk/careers-and-...