So excited that the theme of LGBT+ History Month UK 2026 is 'Science and Innovation,' with super badge designed by @canopyrobin.com! 🧬🏳️‍⚧️🔭🏳️‍🌈🚆 Wonderful launch event at the Royal Society of Chemistry @rsc.org this evening. 👏 lgbtplushistorymonth.co.uk/lgbt-history... @lgbthm.bsky.social #LGBTplusHM 🌈🗃️

Growth-coupled microbial biosynthesis of the animal pigment xanthommatin — Led by Leah Bushin, featuring M. Gracia Alvan, @danielvolke.bsky.social @oscarpuiggene.bsky.social in a fantastic collaboration w/Brad Moore @labnikel.bsky.social @natbiotech.nature.com 🦑 www.nature.com/articles/s41...

🚨 New paper in mBio! We established strict formatotrophic & methylotrophic growth in engineered Pseudomonas putida via the reductive glycine pathway (rGlyP). journals.asm.org/doi/full/10.... Here’s a teaser of how we did it 🧵👇1/5

3/4 Our perspective lays out: 1️⃣ A blueprint for designing next-gen synthetic C1 microbes 2️⃣ A roadmap for engineering P. putida into an autotrophic chassis 3️⃣ A circular carbon economy vision, revalorizing CO₂ + waste streams 📊 Together, these steps connect design → engineering → sustainability.

🚀 Thrilled to share our new Nature Communications article: “A blueprint for designing the next-generation of synthetic C1 microbes” We propose a framework to unlock sustainable, carbon-efficient biomanufacturing using non-canonical hosts. 🔗 www.nature.com/articles/s41... A short 🧵1/4

A blueprint for designing the next-generation of #synthetic C1 #microbes @natureportfolio.nature.com / We outline how to engineer non-canonical hosts, apply modeling & C1-inducible promoters & integrate sustainability metrics for carbon-efficient #biomanufacturing www.nature.com/articles/s41...

The very 1st #Course on #SynBio & #Metabolic #Engineering of #Pseudomonas at Cold Spring Harbor Asia successfully completed in Suzhou, #China! Excellent group of students & lecturers, w/time for culture, food & stand-up paddling alongside the science—thanks to all who participated & stay tuned 4+!

Welcome to the social media account of the International Microbiology Literacy Initiative (IMiLI). Nearly 1,000 researchers freely contribute to the IMiLI project integrating microbiology into education providing downloadable resources for all. Explore at imili.org

Who is afraid of HGT? True, antibiotic resistances disseminate through it. But we can also leverage the same channels for spreading good stuff at a very large scale and fortifying the env microbiome with beneficial activities www.biorxiv.org/content/10.1... by Victor Maull & @ricardsole.bsky.social

We are deeply saddened by the news that Andrew D. Hanson (@adhansonlab.bsky.social) is no longer with us. He was an exceptional scientist, mentor, and leader in multiple fields. He constantly reminded us that over-promising would backfire. Rest in peace, Andrew.

Delighted to join #MetabolicEngineering as Associate Editor w/Sang Yup Lee, Jay Keasling, I. Borodina, C. Maranas & C. Wittmann. I'll handle submissions in #SyntheticMetabolism, #Pseudomonas, #SynBio, new-to-nature #bioproduction & #EnvironmentalBiotechnology!

Saying goodbye to Elio Schaechter, a titan of the #Microbiology field. Farewell Elio!

#Synthetic C1 #metabolism in #Pseudomonas putida enables strict formatotrophy and methylotrophy via the reductive glycine pathway—led by J. Turlin, M. G. Alván, @oscarpuiggene.bsky.social w/@stefanodonati.bsky.social & @sebwenk.bsky.social @mbio.bsky.social #SynBio journals.asm.org/doi/10.1128/...

🔍Problems with synthetic C1 metabolism? The @pabnik.bsky.social group identifies seven major barriers limiting its deployment in microorganisms and proposes specific strategies to overcome each of them. Check out their paper 👉https://doi.org/10.1093/femsre/fuaf011

📍 Milan | TODAY! Join Amedea Perfumo & @pabnik.bsky.social at #FEMS 2025 for a dynamic session🧬 "Something (very) old, something new: Innovative microbial solutions for sustainability challenges 🕦 15 July | 11:30–13:00 | Tower Lounge 🔗 femsmicro.org ▶️ youtu.be/0-bhcMpjJ_c #TolerateEUProject

Looking forward to see old MicroFriends and make some new ones at #FEMS2025!

Check out our newest article led by @oscarpuiggene.bsky.social !

The 5th edition of the #Pseudomonas grass roots meeting will take place on the 27th/28th of October 2025 in Denmark. This year, our group at DTU Biosustain will host 2 exciting days of networking, exchanging ideas and learning for early career-stage scientists working with Pseudomonas. 👇

🧬 The language of SEVA expands! The group of @pabnik.bsky.social use #SEVAplasmids nomenclature in the design of CIFR—a novel iterative transposon tool for genomic engineering of Gam-negative bacteria. 👉 doi.org/10.1016/j.ym...

🚨 Due to popular demand, the deadline to apply for the @cshlnews.bsky.social course Advanced #SynBio & #Metabolic #Engineering of #Pseudomonas is extended to July 22! #PhD students & #postdocs welcome! 📍Suzhou, China 📅 Sept 7–21 🔗Apply now: csh-asia.org?content/2642

Implementing synthetic serine cycles in #Pseudomonas putida unlock methanol assimilation in our favorite bug w/carbon conservation, led by ÒscarPuiggené @labnikel.bsky.social · #SynBio #MetabolicEngineering #Methanol published in @cp-trendsbiotech.bsky.social www.sciencedirect.com/science/arti...

Today, the #TOLERATEProject held its 1st Review Meeting (M1–M18) with PO & PM highlighting our progress, innovation & first results. A key step to shape the road ahead! 🔬🌱💦 Learn more: https://tolerate-eu-project.com/  #HorizonEurope #EUProjects #Biotechnology #SustainableAgriculture

🌱⚖️ Is EU law keeping up with agri-food innovation? Our latest TOLERATE article explores how outdated GMO/NGT rules could hinder progress. Thanks to Mirta Alessandrini & Francesco Montanari for their legal insights. 👉 Read more: tolerate-eu-project.com/tolerate-agr...

Back from an inspiring week at #ME16 in our home #Copenhagen! 🌍 Engaging talks, exciting science, and amazing connections — we’re full of new ideas! 🎉 Big congrats to @giusifav.bsky.social for winning a poster award 🏆 🙌 And proud to have our PI @pabnik.bsky.social as co-chair of the event!

Wrapping up a fantastic #ME16 #Copenhagen — a success by all measures! Honored to co-chair the meeting w/I. Borodina, M. Chang, A. Mirończuk, C. Vickers, V. Šťovíček, Y. Zhou, M. Köpke & M. Herrgård & to work w/an outstanding team of colleagues, engaging communities & topics all around the world

Happy to host @kunjapur.bsky.social as a sabbatical #professor at DTU Biosustain, supported by Otto Mønsteds Fond! We share a passion for using #SynBio to engineer #microbes with non-natural building blocks for advanced #biotechology. He’s in #Europe — drop a line to connect & discuss cool #Science!

Great science @pabnik.bsky.social and collaborators!!

#SyntheticBiology postdoctoral position in our group in University of Florida's Horticultural Sciences department. Work is directed evolution to improve enzymes that underlie important crop traits ⬇️

1/2 New paper by our PhD student Sompot Antimanon, where he uses Pseudomonas putida as a biocatalyst for cinnamic acid production in a process that increase water use efficiency. Sompot reached a TRY of T=143 g/L, R= 2.25 g/L/h, and Y 1.50 g/g glc after 8 recycles. www.nature.com/articles/s41...

The #SynMicro Group was est. just last year, with Markus Pötter & myself elected as its first speakers. We were fortunate to welcome @pabnik.bsky.social as our invited speaker, alongside outstanding short lectures from Anna C. Ngo, Tim Stoltmann, Laura da Silva Amorim and Daniel Stukenberg. 2/n

Genetic dissection of cyclic di-GMP signalling in #Pseudomonas aeruginosa via systematic diguanylate cyclase disruption—led by Roman di Martino & Daniel Volke @labnikel.bsky.social @microbiotech.bsky.social #OpenAccess enviromicro-journals.onlinelibrary.wiley.com/doi/full/10....

2/n If you are at #vaam2025, come join us for the Inaugural Symposium of the brand new #Synthetic #Microbiology Group, featuring @pabnik.bsky.social Center for Biosustainability DTU and a line up of rising stars ✨ #microsky @leibniz-dsmz.bsky.social programme.conventus.de/vaam-2025/pr...

A noble aspiration that, if realized, might indeed increase the host country’s prosperity. But right now, how can such initiatives be funded, given: -slowing growth -rising budget deficits -rising, demographically-driven health & pension costs -the need to increase defense spending?

A call for action by Ken Timmis — Academic institutions worldwide must welcome de-funded US researchers · Read the statement here 👇 iums.org/kenneth-timm...

Microbes like Cupriavidus necator naturally grow on #renewable feedstocks ♻️🧫 (CO₂, formate, hydrogen), yet their potential remains untapped due to the lack of efficient genetic tools... 1/2 www.cell.com/trends/biote...

Congrats to Garret for officially becoming Dr. O'Connell! Garret had his Ph.D. viva on synthetic #fluorochemical #metabolism in #Pseudomonas today. Thanks to @tilmweber.bsky.social r.bsky.social, @pavelcito.bsky.social & Esteban Martinez for their insights🧪🦠 #SynBio @labnikel.bsky.social

Our brand new CRISPR/Cas toolkit for genome editing of Cupriavidus necator is out🦠🧬 A joint effort w/ @dellavallesimo.bsky.social and Costas (and many more!) Check 🧵 our long journey for developing a new state-of-the-art for the manipulation of this promising bug 1/n www.cell.com/trends/biote...

Glad to see Julia Vorholt as winner of the @novonesis.com #Biotechnology Prize 2025 for her research on the plant #microbiome — among other achievements (e.g. synthetic C1 assimilation). Amazing and inspiring colleague #WomenInScience @eth-dbiol.bsky.social novonordiskfonden.dk/en/news/pion...

The utilization of #C1-feedstocks, such as methanol, by non-model bacteria demands an in-depth analysis of design alternatives, a modular strategy to identify bottlenecks and efficient solutions within the host #metabolism of the chosen host... www.biorxiv.org/content/10.1...

Spoiler alert: In a few days we will announce around 30 PhD positions for the Cluster of Excellence Circular Bioengineering, one of them in my lab at @bokuvienna.bsky.social on synthetic single carbon pathways in yeast. Stay tuned!

# MicroSky: Engineered archaea for sustainable bisabolene production! Researchers modified Methanosarcina acetivorans to produce α-bisabolene from one-carbon substrates—an eco-friendly alternative to plant-derived or synthetic methods doi.org/10.1111/1751...

We just #published an end-to-end work for the computer-aided design💻, construction🛠️, validation✅, characterization🔬 & application💪 of #auxotroph metabolic sensors, the work-horses of in vivo growth-coupled selection screening systems-using glycolate as test case. 🧵👇1/ www.nature.com/articles/s41...

Computation-aided designs enable developing auxotrophic #metabolic #sensors for wide-range glyoxylate and glycolate detection—spearheaded by Enrico Orsi w/a choral assembly of cool collaborators @naturecomms.bsky.social #SynBio #OpenAccess www.nature.com/articles/s41...

Preprint alert🚨Systematic #engineering of synthetic serine cycles in #Pseudomonas putida uncovers emergent topologies for #methanol assimilation · @biorxivpreprint.bsky.social led by Òscar Puiggené #SynBio #Methylotrophy #CircularEconomy www.biorxiv.org/content/10.1...

Honored to be elected as a Fellow of the #American Academy of #Microbiology! This recognition reflects the incredible work of my past and present collaborators, students, and mentors. Deep gratitude to my nominators and the microbiology community for their support!🏆🌈

Engineering a phi15-based #expression system for stringent #gene expression in #Pseudomonas putida—led by Eveline Lammens & Daniel Volke in a nice collaboration with @roblavigne.bsky.social's team www.nature.com/articles/s42...

#Preprint alert 🚨 Genetic dissection of cyclic di-GMP signaling in #Pseudomonas aeruginosa via diguanylate cyclase disruption―collaboration between our laboratory & Andrea Smania's team in Argentina, led by Roman Martino & Daniel Volke #CRISPR www.biorxiv.org/content/10.1...

#Microbes Saving Lives & Reducing Suffering—led by KenTimmis, this is a call to action for understanding and exploiting microbes & their role in helping humans at the face of current challenges as a global society @microbiotech.bsky.social enviromicro-journals.onlinelibrary.wiley.com/doi/full/10....

CIFR (Clone–Integrate–Flip-out–Repeat): A toolset for iterative #genome and pathway #engineering of Gram-negative #bacteria—our latest contribution led by Filippo Federici & Francesco Luppino #OpenAccess #SynBio www.sciencedirect.com/science/arti...

#MicroSky: Guo et al report that tobacco promoters & IEEs fail in Chlamydomonas chloroplasts but VOR-Rep-mediated minichromosomes dramatically boost heterologous protein expression. This represents a significant leap forward for algae-based protein production! https://doi.org/10.1111/1751-7915.70069