👩‍🔬Can’t find your plasmid? We’ve got you covered! Design your own vector looking for the different pieces to assemble it yourself. All for free 👉 seva-plasmids.com

From a non-model organism to a promising industrial chassis✨. Have a look at the developments on synthetic biology tools and the engineering potential of Halomonas. SEVA plasmids have been used in some of these efforts, check the review 👉 doi.org/10.1186/s129...

🤝Professional labs around the globe are expanding SEVA and its standard. Meet our collaborators and learn about their research! seva-plasmids.com/the-seva-com...

👀 Researchers at University of Warwick explore how to maintain the expression of synthetic gene circuits over time in bacteria. They propose three genetic controllers that improve simple circuit half-life over threefold. Take a look 👉 doi.org/10.1038/s414...

A plasmid stabilization system offers a way to reduce antibiotic reliance in riboflavin bacterial production. Learn more about the solution 👇 👇 doi.org/10.1016/j.sy...

🎄🦠You don’t know what to give your lab team for Christmas this year yet? What about a customised plasmid perfect for your research? Have a look at our #SEVAplasmids database! 👉 seva-plasmids.com/find-your-pl...

💡A ”shred of light” on contaminants detection! A study shows promising combined biosensors for a more effective and rapid detection of toxins and contaminants. Take a look 👉https://doi.org/10.1016/j.bios.2025.117369

📖Have you used our #SEVAplasmids database selector? Consult our glossary for Acronyms and Antibiotics abbreviations to easily filter specific features. 👉https://seva-plasmids.com/find-your-plasmid/

💊 SMARTS biotool for smart #SynBio! This Streptomyces Multiplexed Artificial Control System boosts production of specific secondary metabolites in this species, which contribute to about half of drugs obtained from microorganisms! Learn more about it: doi.org/10.1038/s415...

🧬 Looking for the perfect plasmid? Explore our #SEVAplasmids database. Request any construct for free, or be the first to design one and share it with the community! Join the standard 👉 seva-plasmids.com/find-your-pl...

💡Glutamate from methanol? This study confirms that MscS channels in Bacillus methanolicus are key L-glutamate exporters, suggesting a way to unlock the bacterium’s potential for sustainable methanol-based glutamate production. Take a look 👉 doi.org/10.1111/1751...

🚀 New breakthrough! Researchers from the D-CHAB and the TUM Faculty of Natural Sciences have designed bacterial ABC transporters to efficiently import non-canonical amino acids. This achievement is a significant step towards expanding the genetic code. doi.org/10.1038/s415...

🚀 Take your genetic engineering to the next level! #SEVA plasmids give you a flexible, plug-and-play platform for your #SynBio designs. Mix, match, and build the plasmid you need, all in one place 👇 seva-plasmids.com/find-your-pl...

🤖 GPT goes #SynBio! Researchers at Chinese Academy of Sciences introduce SynBioGPT v2.0, an AI Large Language Model for SynBio that automates knowledge extraction and strain design. Tested on a 100-question SynBio benchmark, it achieved 98% accuracy! Take a look: doi.org/10.1101/2025...

🚨 News on bioremediation! A study published in Nature reveals how by genetically modifying the bacterium Vibrio natriegens, it simultaneously degrades five toxic contaminants in industrial wastewater and saline soils. Read the full article: www.nature.com/articles/d41...

👩🔬 Want to team up with us to expand the #SEVA collection? Contribute your own constructs to our open plasmid repository and help make #SynBio more reproducible for everyone. ✨ Check out our contribution guidelines and join the mission!👇👇 seva-plasmids.com

Designing replication sequences is challenging in #SynBio. Researchers at the Innovative Genomics Institute present OriGEN, a language model generating functional plasmids beyond wild type, capturing the complex mechanisms of biological replication. 👉 doi.org/10.1101/2025...

🚀 Meet Constructive Bio! This biotech turns living bacteria into programmable biofactories creating new classes of polymers. At #SEVA, we love seeing initiatives like this driving innovation in #SynBio. Read more 👉 www.nature.com/articles/s41...

💭 Imagine #SynBio research where every experiment can be easily replicated and labs collaborate seamlessly. No technical hurdles, just shared progress. That’s our vision at #SEVA! Get your free plasmids and join the movement for #standardisation 👉https://seva-plasmids.com/

Pseudomonas chlororaphis is a promising biofactory, but hard to engineer. A new piece of work has characterised its endogenous CRISPR/Cas I–F system and built a precise editing & CRISPRi toolkit, enabling efficient genetic manipulation. Take a look 👉 pubs.acs.org/doi/10.1021/...

Looking for efficient ways to program intercellular communication? 🧬 Researchers at Micalis Institute present a phagemid toolbox —with #SEVA-based variants— for DNA delivery and next-gen multicellular circuits. 👉 doi.org/10.1101/2025...

The evolution of #SynBio advances with new regulatory toolboxes 🧬 This review explores devices from switches & logic gates to memory modules, powering circuits for bioproduction, therapeutics & biosafety — maybe you’ll find the ideal one for your research 👉 doi.org/10.3389/fsyb...

🌊 Marine bacteria like Pseudovibrio hold enormous ecological & biotech potential, still largely unexplored.✨ Discover the new SEVA-based genetic toolbox developed by researchers at the University of Illinois Chicago — opening ways to study their biology & new applications👉 doi.org/10.1128/aem....

What makes a SEVA plasmid unique? It’s built around 3 fundamental modules: 1️⃣ Origin of replication 2️⃣ Selection marker 3️⃣ Cargo With this open standard, you can design predictable and efficient genetic systems in bacteria and yeast. 👉 Learn more here: seva-plasmids.com

🧬 How many plasmids can a single bacterium carry? That’s the question Cholpisit Kiattisewee explores in his review on multi-plasmid systems and their impact on #SynBio. And yes, #SEVA is part of the debate 👀 👉 Read the full article: doi.org/10.1098/rsob...

⚠️ Hold on! Don’t scroll! Still don't know the basic design of a SEVA plasmid? 🧩 Combine modular parts and get your own standard plasmid from @SEVAplasmids for free. Find your match here 👇 seva-plasmids.com

Biology isn’t an exact science — but standardisation helps us get closer to reproducibility and clarity. That’s why @SEVAplasmids created a universal framework for plasmid vector design. Explore it here 👇 seva-plasmids.com

How do you imagine an artificial DNA nucleus? This study presents a synthetic DNA protonucleus that enables localized RNA transcription and condensation into nuclear-like architectures. A novel tool to investigate real nuclear function. Take a look 👉 doi.org/10.1038/s414...

🚀 #SEVA proves its potential once again! @norholm.bsky.social's lab created a new plasmid recombination system in E. coli using SEVAplasmids. Compatible with any copy number, they expand the standardised toolbox for #SynBio 👉 doi.org/10.1038/s420...

⏳ Stop wasting hours searching for the perfect plasmid for your experiment. 👉 Discover @SEVAplasmids — a community-driven, non-profit collection of standardised plasmids. 🔬 Open, reliable, and ready for your research. Check it out here 👇 seva-plasmids.com

📰 A computational analysis reveals 3️⃣ scaling laws of plasmids. Longer plasmids have: 1️⃣fewer copies 2️⃣more protein-coding 3️⃣more metabolic genes And with gradual adoption of chromosome-like features as they become longer. For more details 👉 doi.org/10.1038/s414...

🧬🔧X. autotrophicus, despite its metabolic flexibility and biosynthetic potential, has few genetic tools available. Researchers from Northeastern University introduce a new toolbox for this microbe, enabling optimisation of processes like bioremediation👉https://doi.org/10.1021/acssynbio.4c00455

📢 A study in Nature Communications presents a new framework that integrates scalable orthogonal amplifiers into standardised biological processes, increasing precision, adaptability, and signal-to-noise ratio in complex genetic circuits. Read the full study here👉 doi.org/10.1038/s414...

With #SEVAplasmids you’re just 2 steps away from your ideal plasmid! 1️⃣ Design your plasmid 2️⃣ Fill in the super simple order form That’s it —your customised plasmids will be shipped straight to your lab 🚀 at no cost Start now👉 seva-plasmids.com/contact/

🧑🤝🧑CRISPR/Cpf1 × pSEVA: a powerhouse combo in #SynBio! German researchers applied this strategy in Photorhabdus & Xenorhabdus, boosting production of high-value compounds like safracin B, a precursor to the anti-cancer drug ET-743. Read here👉 doi.org/10.1186/s129...

Meet one of our partners: @proftomellis.bsky.social's Lab, advancing genetically modified living materials. They use bacteria and yeast to create innovative biomaterials and were key in expanding SEVA from bacteria to eukaryotes. Find out more 👉https://www.tomellislab.com/our-research

#SynBio never ceases to amaze: a new study has succeeded in increasing energy metabolism in mammalian cells, algae, and fungi through the expression of E. coli LplA, a lipoylation protein. The result? Read here 👉 doi.org/10.1038/s414...

Why choose between standardisation and adaptability when you can have both? With #SEVA, you can mix and match: ✅ Antibiotic resistance marker ✅ Origins of replication ✅ Cargo modules for your experiment Build your reproducible #SynBio project here👉 seva-plasmids.com

Meet one of our partners: @proftomellis.bsky.social's Lab, advancing genetically modified living materials. They use bacteria and yeast to create innovative biomaterials and were key in expanding SEVA from bacteria to eukaryotes. Find out more 👉https://www.tomellislab.com/our-research

🚨 News for marine biosafety: Chinese researchers engineered a Vibrio natriegens strain, capable of degrading five water organic contaminants: biphenyl, phenol, naphthalene, dibenzofuran, and toluene. Find out how they did it 👉https://doi.org/10.1038/s41586-025-08947-7

⏳Looking for fast genome editing systems? Researchers from @uwaterloo.ca & Chinese Academy of Sciences created an all-in-one plasmid CRISPR/Cas9 system for Pseudomonas putida KT2440, enabling a genome edit in less than 1.5 days. Explore the work 👉 doi.org/10.1186/s129...

3️⃣ 2️⃣ 1️⃣... Not a countdown—it’s the standard code of one of our plasmids! 3️⃣: Cm resistance 2️⃣: RK2 origin of replication 1️⃣: MCS-default cargo Put them together, and voilà: pSEVA321 plasmid. Simple as that! Find more standardised plasmids here👉 seva-plasmids.com/find-your-pl...

Creating complete biosynthetic pathways from scratch can be a nightmare. SubNetX is a tool that helps you design and integrate them into whole-cell models, optimising the production of complex biochemical compounds. Discover how it works 👉 doi.org/10.1038/s414...

Could lignin waste inspire the biomanufacturing of the future? An international team evolved Acinetobacter baylyi to consume multiple lignin-derived aromatics simultaneously, paving the way for circular bio-based production. Read the article: 👉 doi.org/10.1093/jamb...

SynBio still needs tools enabling independent & precise co-expression of multiple genes. Researchers at Wrocław University presented a new plasmid set with 4 regulatory systems applied in E.coli, enabling independent induction of up to 3 genes in a single vector. Learn more 👉 doi.org/10.1186/s130...

🧬 Simplify your genetic engineering! #SEVAplasmids offers a growing collection of modular, “plug-and-play” plasmids designed to accelerate #SynBio workflows. Choose, combine, and customise with confidence thanks to our clear standards. 👉 seva-plasmids.com

New #SynBio tool! Juan Nogales' lab presents GENIO, a platform for precise genome integration in Pseudomonas putida inspired by #SEVAplasmids’ modular design. It helps you optimise genetic circuit performance for complex synbio design. Learn more: doi.org/10.1111/1751...

🎯 Looking for a plasmid with specific features? Use our #SEVAplasmids selector to filter by origin, antibiotic resistance, or cargo. 👉 Find your right tool in seconds: seva-plasmids.com/select-a-pla...

🔬 A new microbial platform shows enhanced resistance to heavy metals thanks to phosphomelanin biosynthesis—plus it degrades metallised plastic waste! This could offer promising options for environmental cleanup. Read more 👉 doi.org/10.1038/s414...

🧬 Understanding a plasmid’s structure at a glance? Our interactive map makes it possible. Explore SEVA’s modular architecture and its standardised nomenclature.🔍 ORI, markers, cargo… all just one click away 👉 seva-plasmids.com/backbone-mod...