An automated workflow for high-precision genotyping of transposon variants with minimal manual intervention 🚫🤲🏼 Once again, #SEVA⭕✨steps forward to assure scalability and reproducibility for the #SynBio community. Read the study here 👉 bit.ly/4vAkSAb

Generative AI is changing synthetic biology 🧬🤖 with an immense potential for plasmid design⭕ The era of precision design is just around the corner⚙️✨ Read more here 👉 bit.ly/4uqPxz1

SEVA’s ⭕ LEGO style! Build your plasmid: 1️⃣ Pick a Marker. 2️⃣ Select an Origin. 3️⃣ Snap in a Gadget. 4️⃣ Add the Cargo. Start: 👉 acortar.link/G9uSJA

Pooled rAAV libraries might be noisier than we think! This study reveals that packaging recombinant AAV libraries as a pool leads to extensive chimerism due to "barcode swapping" 🧬🔀🧬 At #SEVA ⭕, we believe that standardisation can be a good strategy to prevent this. Read here 👉 doi.org/q42d

Rare codons slowing down your protein expression? 🛑 pCODE plasmids are an elegant solution to rescue recombinant protein production by overexpressing tRNAs! ✨ Proudly, #SEVAplasmids⭕ were used to design this new system. Check out 👉 doi.org/q42c

🧬 Balancing genes in one cell has always been a great challenge! 🧑‍🔬 This review shows the shift from simple co-expression setups to more complex systems. It highlights the contribution of #SEVA⭕✨ as a key step toward modular, programmable designs. Read here👉 doi.org/q4z9

🧑‍🔬 "The question is no longer whether labs can automate, but how far they should go". A recent article in R&D World magazine discusses the future of laboratory work and the impact of AI. 👉

🧑‍🔬Easy to design, easy to order, free of charge… It sounds like a dream, but it is not! In SEVA plasmids we want you to be able to get the exact plasmid you need, so we created an open designing platform to create your own! Try it our yourself!👉

🤔The ins and outs of membrane fusion, as told by experts from the University of Genova and Max Planck Institute. This last review brings together insights on the impact of lipid composition, environmental conditions, and fusogenic agents on this essential biological process👉 doi.org/10.1080/2374...

🧑‍🔧⭕Let’s dissect a SEVA plasmid! Built on a modular architecture, our plasmids make it easier to identify key vector elements. 🧬Origin of replication: more then 15 types 🔆Cargo region: such as cloning or CRSIPR. 💊Antibiotic marker: choose it from out of 10 possibilities. 👉 shorturl.at/04ZtK

Better vector design can make all the difference 🔬 Researchers examined how plasmid vectors are optimized for gene editing and genetic engineering. They focused on 🔧function 📈efficiency 🔀and versatility in #biotech applications Just how SEVA likes it.👉 Read their insights here: doi.org/qz47

Designing plasmids shouldn’t be blocking your experiment 🧬 ⭕SEVA plasmids provide a shared framework for vector construction, helping researchers work with greater flexibility and #reproducibility in biotechnology and microbial engineering. Explore our website👉

🔬New model systems are helping reshape drug discovery. Nowadays there are more relevant ways to study disease biology, and improve early-stage screening. TheScientist has reviewed the latest advances in this new guide about how to use in vitro models 👉https://shorturl.at/DXbIg

Methanol as feedstock? Maybe not for us but… 🧪 Resarchers built new biology toolkit to help microbes grow using methanol, making them easier to engineer and more stable. 👉Read how they managed to do it:

👩‍🔬 The #SEVA collection keeps growing thanks to community contributions. Add your constructs to our open plasmid repository and help improve reproducibility in #SynBio. ✨ Check the guidelines and join our mission 👉

🔬Tired of replicating that experiment and getting different results? SEVA simplifies #SynBio with a universal vector system! All SEVA #plasmids follow a standardised format. Reproducibility starts here! ⚙️👉

🧬🖨️ Boosting 3D-printed tissues! MIT engineers have developed a compact magnetic mixer that keeps bioinks uniformly mixed during printing. This makes engineered tissues more reproducible and scalable – just like SEVA likes it! Check the whole story👉

🔭New plasmids on the horizon! Scientists from @bfrde.bsky.social detected megaplasmids in enteropathogenic Vibrio spp. These have 80% unclassified genes! ⭕What’s more, the megaplasmids suggest a non-Vibrio origin 👉

💪An easy way to gain glucose! Scientists have developed a plasmid-free and inducer-free Escherichia coli to produce glucose. This may be an interesting way of reducing expenses💸. Read how they could do it👉

🛠️✨We are the Standard European Vector Architecture (SEVA), a web-based resource in which you can choose the #plasmid that you need for your research. Our goal is to make #reproducibility, a reality. Check them out 👉

🔬SEVA format involves a set of rules to unify the scientific community. These are visible in our #plasmid nomenclature. By order: 🦠 Antibiotic resistance marker ⭕ Origin of replication 📦 Cargo module 🛠️ Optional gadgets Learn how it works here 👉https://shorturl.at/V5ff1

Using photosynthesis as a work chain ☀️ Researchers aimed to engineer cells that can capture light and use it to produce valuable compounds. 🦠They successfully reprogrammed E. coli to perform efficient photobiosynthesis of several products! 👉

⭕❌What would happen if organisms with and without plasmids compete? I will give you a hint: this plasmid-bearing population can produce an allelopathic toxin that is lethal to its plasmid-free competitor, and yet, who wins?👉

⭕✨Standard, tailor-made, and send directly to your door food free. Too good can be true. Take a look at our website and check our vectors free of charge 👉

🦠✨This bacterium can act as a “sickness traffic light”. @ctropini.bsky.social and her group from the University of British Columbia have engineered a system in which cells that normally produce GFP reduce their fluorescence under stress conditions. Discover the full story 👉https://shorturl.at/f9bpu

❓🦠With N, what is the main cause of foodborne illness? Non-typhoidal Salmonella! In it, plasmids enhance adaptability, combining resistance and virulence. Microbiota-targeted or CRISPR-based tools can provide opportunities to disrupt plasmid dissemination. 👉Check how:

Science anywhere? Absolutely yes! Science anyhow? No please! The #SEVA database of vector plasmids aims to improve Science replication and create a world in which high-quality science is available no matter where. Join us! 👉 seva-plasmids.com

The @berkeleylab.lbl.gov presented the Global Soil Plasmidome Resource. A comprehensive dataset of 98,728 plasmid sequences amassed from 6860 terrestrial microbial communities and isolates. Check them out!👉 www.nature.com/articles/s41...

Replicable science requires shared standards. The #SEVA platform provides modular, standardized plasmid vectors that improve reproducibility and design. Explore the SEVA collection and order validated plasmids for free 👉 seva-plasmids.com/find-your-pl...

🌍🧬 Plasmids are spreading antibiotic resistance across European urban water systems. A multi-omics survey found tens of thousands of plasmids carrying resistance genes, many previously unknown. It highlights how wastewater networks share and mobilize ARGs across borders 👉https://doi.org/qn2v

🧬📊 Read this comparative review of plasmid vectors used in gene editing and genetic engineering. It highlights how designing elements such as replication origin, host range, and CRISPR compatibility affect multiple features. How important it is to make the right selection? 👉

If you are a researcher working with plasmids, this is for you!👩🏾‍🔬🔬Standard, effective and ✨free✨, what else can you ask for? Take a look at our website and find your #SEVAplasmid ready to use 👉

🧬🔧 New tools keep emerging for mycobacterial protein production. This plasmid-based system enables translationally gated secretion in Mycobacterium, combining riboswitch control with highly efficient extracellular export. A new layer of regulation unlocked👉

A free, worldwide and standardized tool for researchers 🧑‍🔬🛠️ It seems too good to be true, but it exists! ⭕Our #SEVA plasmids accomplish all those characteristics to help scientific research succeed. Use them yourself! 👉

🩸🩹You may have heard about using glue to stop bleedings. Maybe it is not the best strategy in the world, but scientists have engineered bacteria to function as therapeutic ‘living glues’ inside your body! 😳. Check how they do it 👉

⭕ Plasmids of the group lncP-1 replicate and usually persist in many bacteria, but nothing in nature comes without exception. The lncP-1𝛃 plasmid pBP136 became extinct in E.coli at the lab. Scientists from the @uidaho.bsky.social suspect which gene is guilty. 👉

🧬Plasmids are the workhorses of molecular biology, but are we really choosing them wisely? @vdlorenzo.bsky.social and Esteban Martínez-García revisit what really defines plasmid performance and why modular standards like #SEVA matter for the future of #SynBio 👉https://doi.org/10.1111/1751-7915.70273

Have you already found your pSEVA plasmid match for your #SynBio project? You’re just one step away! 🚀 📤 Visit our website and choose the gateway to your next experiment—free, open, and ready to use 👉https://seva-plasmids.com/contact/

♻️🦠Tackling mixed plastics! See the potential of engineered microbial consortia to upcycle complex mixed plastic waste. Integrating transition metal-free plastic depolymerization with the strengths of each bacterial specialist and division of labor 👇 doi.org/10.1038/s414...

In need of a new #SEVA construct? Contributing to the community and to the plasmid repository is simple: 1. Remove unwanted and extra restriction sites 2. Flank every module with the appropriate SEVA-standard sites 3. Send your construct! 📋Check all the details seva-plasmids.com/description/...

🔬Investigating viral infections in a controlled way: researchers establish a cell-free T7 phage cycle on synthetic cells. A simplified but promising in vitro system for studying viral infection variables, phage-host interactions, and more. Full story👇 doi.org/10.1038/s414...

🦠⏩Beyond traditional organisms, broad-host-range synthetic biology offers a powerful framework for innovation, expanding chassis selection and rethinking their role in genetic design. Take a look at the perspective paper doi.org/10.1021/acss...

Let’s break down a pSEVA plasmid’s mix-and-match available modules! 🔵 Antibiotic resistance marker 🟡 Origin of replication 🔴 Cargo 🟢 and optional gadget Check our user-friendly platform and find the plasmids with the ideal modules for your research! 👉 seva-plasmids.com/find-your-pl...

🧬How selective pressures shape plasmid evolution within the host cell? Scientists have measured within-cell fitness of competing plasmids, revealing new insights into cell and plasmid dynamics and into how antibiotic resistance evolves in bacteria! Take a deeper look doi.org/10.1126/scie...

👩‍🔬Researchers use a SEVA plasmid to help develop citrOgen. A rapid platform that repurposes Citrobacter rodentium to present antigens from high-priority human pathogens, triggering the host to produce protective antibodies🛡️. 👉https://doi.org/10.1038/s41467-025-63922-0

A standardised plasmid repository for experimental replicability ⭕. Check #SEVAplasmids database and join the movement! 👉 seva-plasmids.com/find-your-pl...

✨And with that the 2025 season comes to an end... But at SEVA we continue working for a replicable and reliable science🤝 We want to thank you all for your support through this past year, and we can’t wait for all the surprises 2026 will bring! 🤩

📋Your plasmid and your plasmid documentation all in one place! Have a look at the possibility of plasmids with self-encoded documentation files 👉 doi.org/10.1016/j.ti...

👩‍🔬Can’t find your plasmid? We’ve got you covered! Design your own vector looking for the different pieces to assemble it yourself. All for free 👉 seva-plasmids.com

From a non-model organism to a promising industrial chassis✨. Have a look at the developments on synthetic biology tools and the engineering potential of Halomonas. SEVA plasmids have been used in some of these efforts, check the review 👉 doi.org/10.1186/s129...