🔬Tired of replicating that experiment and getting different results? SEVA simplifies #SynBio with a universal vector system! All SEVA #plasmids follow a standardised format. Reproducibility starts here! ⚙️👉

🧬🖨️ Boosting 3D-printed tissues! MIT engineers have developed a compact magnetic mixer that keeps bioinks uniformly mixed during printing. This makes engineered tissues more reproducible and scalable – just like SEVA likes it! Check the whole story👉

🔭New plasmids on the horizon! Scientists from @bfrde.bsky.social detected megaplasmids in enteropathogenic Vibrio spp. These have 80% unclassified genes! ⭕What’s more, the megaplasmids suggest a non-Vibrio origin 👉

💪An easy way to gain glucose! Scientists have developed a plasmid-free and inducer-free Escherichia coli to produce glucose. This may be an interesting way of reducing expenses💸. Read how they could do it👉

🛠️✨We are the Standard European Vector Architecture (SEVA), a web-based resource in which you can choose the #plasmid that you need for your research. Our goal is to make #reproducibility, a reality. Check them out 👉

🔬SEVA format involves a set of rules to unify the scientific community. These are visible in our #plasmid nomenclature. By order: 🦠 Antibiotic resistance marker ⭕ Origin of replication 📦 Cargo module 🛠️ Optional gadgets Learn how it works here 👉https://shorturl.at/V5ff1

Using photosynthesis as a work chain ☀️ Researchers aimed to engineer cells that can capture light and use it to produce valuable compounds. 🦠They successfully reprogrammed E. coli to perform efficient photobiosynthesis of several products! 👉

⭕❌What would happen if organisms with and without plasmids compete? I will give you a hint: this plasmid-bearing population can produce an allelopathic toxin that is lethal to its plasmid-free competitor, and yet, who wins?👉

⭕✨Standard, tailor-made, and send directly to your door food free. Too good can be true. Take a look at our website and check our vectors free of charge 👉

🦠✨This bacterium can act as a “sickness traffic light”. @ctropini.bsky.social and her group from the University of British Columbia have engineered a system in which cells that normally produce GFP reduce their fluorescence under stress conditions. Discover the full story 👉https://shorturl.at/f9bpu

❓🦠With N, what is the main cause of foodborne illness? Non-typhoidal Salmonella! In it, plasmids enhance adaptability, combining resistance and virulence. Microbiota-targeted or CRISPR-based tools can provide opportunities to disrupt plasmid dissemination. 👉Check how:

Science anywhere? Absolutely yes! Science anyhow? No please! The #SEVA database of vector plasmids aims to improve Science replication and create a world in which high-quality science is available no matter where. Join us! 👉 seva-plasmids.com

The @berkeleylab.lbl.gov presented the Global Soil Plasmidome Resource. A comprehensive dataset of 98,728 plasmid sequences amassed from 6860 terrestrial microbial communities and isolates. Check them out!👉 www.nature.com/articles/s41...

Replicable science requires shared standards. The #SEVA platform provides modular, standardized plasmid vectors that improve reproducibility and design. Explore the SEVA collection and order validated plasmids for free 👉 seva-plasmids.com/find-your-pl...

🌍🧬 Plasmids are spreading antibiotic resistance across European urban water systems. A multi-omics survey found tens of thousands of plasmids carrying resistance genes, many previously unknown. It highlights how wastewater networks share and mobilize ARGs across borders 👉https://doi.org/qn2v

🧬📊 Read this comparative review of plasmid vectors used in gene editing and genetic engineering. It highlights how designing elements such as replication origin, host range, and CRISPR compatibility affect multiple features. How important it is to make the right selection? 👉

If you are a researcher working with plasmids, this is for you!👩🏾‍🔬🔬Standard, effective and ✨free✨, what else can you ask for? Take a look at our website and find your #SEVAplasmid ready to use 👉

🧬🔧 New tools keep emerging for mycobacterial protein production. This plasmid-based system enables translationally gated secretion in Mycobacterium, combining riboswitch control with highly efficient extracellular export. A new layer of regulation unlocked👉

A free, worldwide and standardized tool for researchers 🧑‍🔬🛠️ It seems too good to be true, but it exists! ⭕Our #SEVA plasmids accomplish all those characteristics to help scientific research succeed. Use them yourself! 👉

🩸🩹You may have heard about using glue to stop bleedings. Maybe it is not the best strategy in the world, but scientists have engineered bacteria to function as therapeutic ‘living glues’ inside your body! 😳. Check how they do it 👉

⭕ Plasmids of the group lncP-1 replicate and usually persist in many bacteria, but nothing in nature comes without exception. The lncP-1𝛃 plasmid pBP136 became extinct in E.coli at the lab. Scientists from the @uidaho.bsky.social suspect which gene is guilty. 👉

🧬Plasmids are the workhorses of molecular biology, but are we really choosing them wisely? @vdlorenzo.bsky.social and Esteban Martínez-García revisit what really defines plasmid performance and why modular standards like #SEVA matter for the future of #SynBio 👉https://doi.org/10.1111/1751-7915.70273

Have you already found your pSEVA plasmid match for your #SynBio project? You’re just one step away! 🚀 📤 Visit our website and choose the gateway to your next experiment—free, open, and ready to use 👉https://seva-plasmids.com/contact/

♻️🦠Tackling mixed plastics! See the potential of engineered microbial consortia to upcycle complex mixed plastic waste. Integrating transition metal-free plastic depolymerization with the strengths of each bacterial specialist and division of labor 👇 doi.org/10.1038/s414...

In need of a new #SEVA construct? Contributing to the community and to the plasmid repository is simple: 1. Remove unwanted and extra restriction sites 2. Flank every module with the appropriate SEVA-standard sites 3. Send your construct! 📋Check all the details seva-plasmids.com/description/...

🔬Investigating viral infections in a controlled way: researchers establish a cell-free T7 phage cycle on synthetic cells. A simplified but promising in vitro system for studying viral infection variables, phage-host interactions, and more. Full story👇 doi.org/10.1038/s414...

🦠⏩Beyond traditional organisms, broad-host-range synthetic biology offers a powerful framework for innovation, expanding chassis selection and rethinking their role in genetic design. Take a look at the perspective paper doi.org/10.1021/acss...

Let’s break down a pSEVA plasmid’s mix-and-match available modules! 🔵 Antibiotic resistance marker 🟡 Origin of replication 🔴 Cargo 🟢 and optional gadget Check our user-friendly platform and find the plasmids with the ideal modules for your research! 👉 seva-plasmids.com/find-your-pl...

🧬How selective pressures shape plasmid evolution within the host cell? Scientists have measured within-cell fitness of competing plasmids, revealing new insights into cell and plasmid dynamics and into how antibiotic resistance evolves in bacteria! Take a deeper look doi.org/10.1126/scie...

👩‍🔬Researchers use a SEVA plasmid to help develop citrOgen. A rapid platform that repurposes Citrobacter rodentium to present antigens from high-priority human pathogens, triggering the host to produce protective antibodies🛡️. 👉https://doi.org/10.1038/s41467-025-63922-0

A standardised plasmid repository for experimental replicability ⭕. Check #SEVAplasmids database and join the movement! 👉 seva-plasmids.com/find-your-pl...

✨And with that the 2025 season comes to an end... But at SEVA we continue working for a replicable and reliable science🤝 We want to thank you all for your support through this past year, and we can’t wait for all the surprises 2026 will bring! 🤩

📋Your plasmid and your plasmid documentation all in one place! Have a look at the possibility of plasmids with self-encoded documentation files 👉 doi.org/10.1016/j.ti...

👩‍🔬Can’t find your plasmid? We’ve got you covered! Design your own vector looking for the different pieces to assemble it yourself. All for free 👉 seva-plasmids.com

From a non-model organism to a promising industrial chassis✨. Have a look at the developments on synthetic biology tools and the engineering potential of Halomonas. SEVA plasmids have been used in some of these efforts, check the review 👉 doi.org/10.1186/s129...

🤝Professional labs around the globe are expanding SEVA and its standard. Meet our collaborators and learn about their research! seva-plasmids.com/the-seva-com...

👀 Researchers at University of Warwick explore how to maintain the expression of synthetic gene circuits over time in bacteria. They propose three genetic controllers that improve simple circuit half-life over threefold. Take a look 👉 doi.org/10.1038/s414...

A plasmid stabilization system offers a way to reduce antibiotic reliance in riboflavin bacterial production. Learn more about the solution 👇 👇 doi.org/10.1016/j.sy...

🎄🦠You don’t know what to give your lab team for Christmas this year yet? What about a customised plasmid perfect for your research? Have a look at our #SEVAplasmids database! 👉 seva-plasmids.com/find-your-pl...

💡A ”shred of light” on contaminants detection! A study shows promising combined biosensors for a more effective and rapid detection of toxins and contaminants. Take a look 👉https://doi.org/10.1016/j.bios.2025.117369

📖Have you used our #SEVAplasmids database selector? Consult our glossary for Acronyms and Antibiotics abbreviations to easily filter specific features. 👉https://seva-plasmids.com/find-your-plasmid/

💊 SMARTS biotool for smart #SynBio! This Streptomyces Multiplexed Artificial Control System boosts production of specific secondary metabolites in this species, which contribute to about half of drugs obtained from microorganisms! Learn more about it: doi.org/10.1038/s415...

🧬 Looking for the perfect plasmid? Explore our #SEVAplasmids database. Request any construct for free, or be the first to design one and share it with the community! Join the standard 👉 seva-plasmids.com/find-your-pl...

💡Glutamate from methanol? This study confirms that MscS channels in Bacillus methanolicus are key L-glutamate exporters, suggesting a way to unlock the bacterium’s potential for sustainable methanol-based glutamate production. Take a look 👉 doi.org/10.1111/1751...

🚀 New breakthrough! Researchers from the D-CHAB and the TUM Faculty of Natural Sciences have designed bacterial ABC transporters to efficiently import non-canonical amino acids. This achievement is a significant step towards expanding the genetic code. doi.org/10.1038/s415...

🚀 Take your genetic engineering to the next level! #SEVA plasmids give you a flexible, plug-and-play platform for your #SynBio designs. Mix, match, and build the plasmid you need, all in one place 👇 seva-plasmids.com/find-your-pl...

🤖 GPT goes #SynBio! Researchers at Chinese Academy of Sciences introduce SynBioGPT v2.0, an AI Large Language Model for SynBio that automates knowledge extraction and strain design. Tested on a 100-question SynBio benchmark, it achieved 98% accuracy! Take a look: doi.org/10.1101/2025...

🚨 News on bioremediation! A study published in Nature reveals how by genetically modifying the bacterium Vibrio natriegens, it simultaneously degrades five toxic contaminants in industrial wastewater and saline soils. Read the full article: www.nature.com/articles/d41...

👩🔬 Want to team up with us to expand the #SEVA collection? Contribute your own constructs to our open plasmid repository and help make #SynBio more reproducible for everyone. ✨ Check out our contribution guidelines and join the mission!👇👇 seva-plasmids.com

Designing replication sequences is challenging in #SynBio. Researchers at the Innovative Genomics Institute present OriGEN, a language model generating functional plasmids beyond wild type, capturing the complex mechanisms of biological replication. 👉 doi.org/10.1101/2025...