One week left to apply for the EMBO/FEBS lecture course on #ionchannels and #transporters in beautiful Erice in May 2026: meetings.embo.org/event/26-ion... Please share

Cryo-EM structures of human P2X2/3 heteromer channel reveal the structural basis of ligand selectivity pubmed.ncbi.nlm.nih.gov/41931608/ #cryoem

Excited to be on my way to the Ligand Recognition and Molecular Gating GRC - many of our present projects started at this meeting 10 (!) years ago! @Nalcn @Split inteins

New OpenFold3 preview out! (OF3p2) It closes the gap to AlphaFold3 for most modalities. Most critically, we're releasing everything, including training sets & configs, making OF3p2 the only current AF3-based model that is functionally trainable & reproducible from scratch🧵1/9

Keep calm and be transparent: advice from scientists who retracted their papers www.nature.com/articles/d41... @elisabethbik.bsky.social

3000th clone added to our clone library. Happy weekend

Sudha (@chakrapanilab.bsky.social) and Julio (@cvlab.bsky.social) are organizing the 2026 Ion Channel Gordon Research Conference: Ion Channels Across Scales — Bridging Molecular Events to Physiological Outcomes, to be held at Mount Holyoke College, July 12–17, 2026. 1/3

Kicking off 2026 on a positive note! Check out our latest work on developmental channelopathies. #IonChannels #NALCN #IHPRF1

Time to sign up! Registration for the joint FEBS/EMBO course on ion channels and transporters in Erice, Italy (May 13-19th 2026) is now open: meetings.embo.org/event/26-ion... Please share and repost.

Lorne Proteins 2026 🏖️ Leach Lecturer Carol Robinson, Oxford, on establishing mass spec as a viable technique for structure/function studies; and John Kuriyan, Vanderbilt University, on the structural plasticity and evolutionary potential of DNA clamp loaders. 🔗 Register now: www.lorneproteins.org

A new community-driven lab handbook for reducing conflict and creating more positive and equitable work environments gets strong support from a survey of 200 researchers. buff.ly/K7CGFLV

To all trainees interested in channels and transporters: the joint FEBS/EMBO course will go ahead in Erice, Italy from May 13-19 2026: network.febs.org/posts/new-jo... Further details to come soon. Please share and repost.

PhD students and Postdocs: The Night Science Podcast (@nightsciencepod.bsky.social) is producing an episode highlighting young scientists talking about their creative process. DM me if you'd like us to consider you for this, & read below what PhD student Davis Garner will contribute! ⬇️

Game changer, no doubt. Commercial systems will have expensive consumables I suppose, but huge savings to be made in cell culture, and many important but sparse native targets come into play. Crispr-tagged targets from iPSC neurons, for example. TRPC6 blind? 🤯

Very grateful to have been able to attend the second-ever NALCN conference. This provided a fantastic opportunity to catch up with collaborators and meet patients and families affected by NALCN-related diseases. Huge thanks to everyone at the Channeling Hope Foundation for making this event happen!

Phosphorylation on tyrosines control key pathways in immunity, cancer, and metabolism. For the first time, we can now design proteins that specifically recognize individual phosphotyrosines, even in disordered regions. (1/8) Preprint: www.biorxiv.org/content/10.1...

When I started working on ion channels 20+ yrs ago, I could have never imagined how many channels there are to explore! Now I’m delighted to be heading to thematic meetings on two of our favorite channels in the span of just weeks - can’t wait to catch up with the ASIC and NALCN communities!

After years in making, I am glad to be able to share our attempt on establishing a framework for combined functional and computational assessment of variant pathogenicity in the sodium leak channel NALCN: www.biorxiv.org/content/10.1...

Momentum is building! Join us for the 51st Lorne Proteins Conference Feb 8–12, 2026, Mantra Lorne on the Great Ocean Road, for fun networking activities 🏐 🎾 🥗 🪩 and breathtaking surf-coast accessibility 🏖️ 🏊 🏄 in the generous breaks between sessions! 🔗 Register here: www.lorneproteins.org/register

Come to the second edition of the world wide sodium channel conference! Submit an abstract by September 26.

Adriano Senatore @utoronto.ca and colleagues explore the evolutionary origins of the sodium leak channel NALCN and its ancillary subunits FAM155/Mid1, UNC79, and UNC80. rupress.org/jgp/article/... #Evolution #IonChannels

2nd #WSCC26 will take place in Grindelwald (Switzerland) 🚠 from 4th to 6th of February, 2026. 🌍 Join @lampertlab.bsky.social , @antoniospantazis.bsky.social, @khannalabuf.bsky.social, and others. 💡 Submit abstracts by the 26th of September, 2025: lnkd.in/eDhPUVKd 💻 More info: lnkd.in/eJw9pfMz

Wonderful visit to beautiful Bergen, Norway. Big thanks to @herculeria.bsky.social for hosting and to Tim Lynagh for guiding me up the local hills

🥁🥁🥁 The 51st Lorne Conference on Protein Structure and Function is officially live! After the resounding success of the 50th Lorne Conference in 2025 celebrating five decades of pioneering science and community, the legacy continues... 🏄🏖️🌞 February 8–12, 2026 Register here: www.lorneproteins.org

Friends don’t use friend’s plasmids without sequencing them. For some types of plasmids from academic and industrial labs, up to 40% contained mutations academic.oup.com/nar/article/...

Villum Sabbatical grant: For US-based researchers wishing to visit a Danish university for up to 12 months Deadline Aug. 15th 2025 villumfonden.dk/en/group/cha...

🚨 One week left to apply! I am hiring a fully funded PhD fellow and a postdoc to work on membrane protein structural biology and pharmacology at Univ Copenhagen Come work with a great team and exciting projects in a collaborative environment! 🔗 Links to the ads in comments #CryoEM #AcademicJobs

@michaelclerx.com et al. @uniofnottingham.bsky.social present variability in reported midpoints of activation and inactivation for the cardiac fast sodium current, INa, show the correlation between these midpoints, and discuss possible experimental sources of variability. rupress.org/jgp/article/...

We are hiring at the Department of Drug Design and Pharmacology. Check out these opportunities and consider becoming our new colleague at University of Copenhagen. employment.ku.dk/faculty/?sho...

“It’s the company that matters!” This is certainly true for acid-sensing ion channel 1a, whose function is modulated by the presence of monocarboxylate transporter 1 All was made possible by the drive & curiosity of the fantastic @mette-h-poulsen.bsky.social www.biorxiv.org/cgi/content/...

A major KI initiative to recruit new assistant professors with outstanding proposals in all areas of medicine, biomedicine and public health. We offer an amazing research environment, great colleagues and generous startup packages. Check it out and get working on your applications! (repost please!)

Exciting news for protein design!

I guess I should re-post from the Bird Site "The Rules For Academic Success here": I always get asked for advice about starting/surviving the tenure track. Here are the rules I've found useful. Thought I'd put it out there for the masses... This list gets longer all the time

The 3rd Berlin Single Molecule Biophysics Course will run from 8th to 12th September at the HU-Berlin, Institute of Biology. Learn about single channels, single molecule TIRF, theory and analysis. Apply by 7th July at [email protected]. Fee waivers and bursaries available. ! Please share widely !

Great meeting on acid-sensing ion channels coming up in the fall in Germany - make sure to sign up: www.asic-meeting.org

🧵5 Top Free Alternatives to BioRender for Scientific Illustrations! These five websites offer free scientific illustrations for biologists. Great for presentations, research papers and other research communication needs. Save and share the post!

CCeMMP Seminar alert⏰ We welcome Professor Juan Du, Department of Molecular Biosciences, Northwestern University, Illinois, USA! “The importance of Physiological Temperature in Biomedical & Biophysical Research” More details and register: ccemmp.org/events/ccemm...

Very important to keep in mind: Asp/Glu aren’t necessarily always charged!

Heard from a former (undergrad) student who just defended her PhD. Students: tell your old profs about your successes and achievements. It's not bragging, and we love to hear about it. It's one of the best parts of being an educator. #academicsky

Beyond excited to present our study on the glycine transporter #GlyT2, a promising #non-opioid target for the treatment of neuropathic pain. @biorxivpreprint.bsky.social www.biorxiv.org/content/10.1...

Save the date!!! For the first time since 2015, the annual conference of the International Chemical Biology Society comes back to Europe and joins forces with the biennal European Chemical Biology Symposium, to organize #ChemBioParis2025, in the heart of the City of Light. Oct 6-9, 2025.

Structural basis for selective inhibition of human GABA transporter GAT3 https://www.biorxiv.org/content/10.1101/2025.03.27.645797v1

Stellar line up for our protein design conference. Copenhagen, Sept 1-4, 2025. 10 days to abstract deadline. Get applying! benzon-foundation.dk/benzon-sympo...

⏰ Two weeks left to register for our Benzon Symposium on Protein structure prediction and design 🧶🧬🖥️ Meeting will take place in Copenhagen 🇩🇰 on Sept. 1–4, 2025, and will feature an amazing list of speakers 👨‍🔬👩‍🔬👩‍💻👨‍💻 Submit your application via: benzon-foundation.dk/benzon-sympo...

Our latest paper on the sodium leak channel NALCN complex is now online. We found that the neuronal SNARE proteins syntaxin 1A and SNAP25 inhibit sodium leak currents both in heterologous systems and in neurons! www.science.org/doi/10.1126/...

Labeling your axes and then explaining them slowly is perhaps the biggest bang for the buck you can get for making your slides more understandable.

Very grateful to have been able to attend #BPS2025! Big thanks to everyone involved in making this inspiring event possible! At the same time, the meeting was a stark reminder of how politics can interfere with science - and how cost 💲 is a major discriminator of who can and cannot attend!

Congratulations to the three Cole Award recipients at #BPS2025: Baron Chanda Dan Minor Crina Nimigean 👏👏👏👏👏👏

@renaeryan.bsky.social telling us who the three winners of the 2025 Cole Awards are! 🥳🥳🥳 #BPS2025

One more sleep to the @biophysicalsoc.bsky.social CRT Symposium on tomorrow morning bright and early! Join us in Petree Hall C at 8.30am.