Very grateful to have been able to attend the second-ever NALCN conference. This provided a fantastic opportunity to catch up with collaborators and meet patients and families affected by NALCN-related diseases. Huge thanks to everyone at the Channeling Hope Foundation for making this event happen!

Phosphorylation on tyrosines control key pathways in immunity, cancer, and metabolism. For the first time, we can now design proteins that specifically recognize individual phosphotyrosines, even in disordered regions. (1/8) Preprint: www.biorxiv.org/content/10.1...

When I started working on ion channels 20+ yrs ago, I could have never imagined how many channels there are to explore! Now I’m delighted to be heading to thematic meetings on two of our favorite channels in the span of just weeks - can’t wait to catch up with the ASIC and NALCN communities!

After years in making, I am glad to be able to share our attempt on establishing a framework for combined functional and computational assessment of variant pathogenicity in the sodium leak channel NALCN: www.biorxiv.org/content/10.1...

Momentum is building! Join us for the 51st Lorne Proteins Conference Feb 8–12, 2026, Mantra Lorne on the Great Ocean Road, for fun networking activities 🏐 🎾 🥗 🪩 and breathtaking surf-coast accessibility 🏖️ 🏊 🏄 in the generous breaks between sessions! 🔗 Register here: www.lorneproteins.org/register

Come to the second edition of the world wide sodium channel conference! Submit an abstract by September 26.

Adriano Senatore @utoronto.ca and colleagues explore the evolutionary origins of the sodium leak channel NALCN and its ancillary subunits FAM155/Mid1, UNC79, and UNC80. rupress.org/jgp/article/... #Evolution #IonChannels

2nd #WSCC26 will take place in Grindelwald (Switzerland) 🚠 from 4th to 6th of February, 2026. 🌍 Join @lampertlab.bsky.social , @antoniospantazis.bsky.social, @khannalabuf.bsky.social, and others. 💡 Submit abstracts by the 26th of September, 2025: lnkd.in/eDhPUVKd 💻 More info: lnkd.in/eJw9pfMz

Wonderful visit to beautiful Bergen, Norway. Big thanks to @herculeria.bsky.social for hosting and to Tim Lynagh for guiding me up the local hills

🥁🥁🥁 The 51st Lorne Conference on Protein Structure and Function is officially live! After the resounding success of the 50th Lorne Conference in 2025 celebrating five decades of pioneering science and community, the legacy continues... 🏄🏖️🌞 February 8–12, 2026 Register here: www.lorneproteins.org

Friends don’t use friend’s plasmids without sequencing them. For some types of plasmids from academic and industrial labs, up to 40% contained mutations academic.oup.com/nar/article/...

Villum Sabbatical grant: For US-based researchers wishing to visit a Danish university for up to 12 months Deadline Aug. 15th 2025 villumfonden.dk/en/group/cha...

🚨 One week left to apply! I am hiring a fully funded PhD fellow and a postdoc to work on membrane protein structural biology and pharmacology at Univ Copenhagen Come work with a great team and exciting projects in a collaborative environment! 🔗 Links to the ads in comments #CryoEM #AcademicJobs

@michaelclerx.com et al. @uniofnottingham.bsky.social present variability in reported midpoints of activation and inactivation for the cardiac fast sodium current, INa, show the correlation between these midpoints, and discuss possible experimental sources of variability. rupress.org/jgp/article/...

We are hiring at the Department of Drug Design and Pharmacology. Check out these opportunities and consider becoming our new colleague at University of Copenhagen. employment.ku.dk/faculty/?sho...

“It’s the company that matters!” This is certainly true for acid-sensing ion channel 1a, whose function is modulated by the presence of monocarboxylate transporter 1 All was made possible by the drive & curiosity of the fantastic @mette-h-poulsen.bsky.social www.biorxiv.org/cgi/content/...

A major KI initiative to recruit new assistant professors with outstanding proposals in all areas of medicine, biomedicine and public health. We offer an amazing research environment, great colleagues and generous startup packages. Check it out and get working on your applications! (repost please!)

Exciting news for protein design!

I guess I should re-post from the Bird Site "The Rules For Academic Success here": I always get asked for advice about starting/surviving the tenure track. Here are the rules I've found useful. Thought I'd put it out there for the masses... This list gets longer all the time

The 3rd Berlin Single Molecule Biophysics Course will run from 8th to 12th September at the HU-Berlin, Institute of Biology. Learn about single channels, single molecule TIRF, theory and analysis. Apply by 7th July at [email protected]. Fee waivers and bursaries available. ! Please share widely !

Great meeting on acid-sensing ion channels coming up in the fall in Germany - make sure to sign up: www.asic-meeting.org

🧵5 Top Free Alternatives to BioRender for Scientific Illustrations! These five websites offer free scientific illustrations for biologists. Great for presentations, research papers and other research communication needs. Save and share the post!

CCeMMP Seminar alert⏰ We welcome Professor Juan Du, Department of Molecular Biosciences, Northwestern University, Illinois, USA! “The importance of Physiological Temperature in Biomedical & Biophysical Research” More details and register: ccemmp.org/events/ccemm...

Very important to keep in mind: Asp/Glu aren’t necessarily always charged!

Heard from a former (undergrad) student who just defended her PhD. Students: tell your old profs about your successes and achievements. It's not bragging, and we love to hear about it. It's one of the best parts of being an educator. #academicsky

Beyond excited to present our study on the glycine transporter #GlyT2, a promising #non-opioid target for the treatment of neuropathic pain. @biorxivpreprint.bsky.social www.biorxiv.org/content/10.1...

Save the date!!! For the first time since 2015, the annual conference of the International Chemical Biology Society comes back to Europe and joins forces with the biennal European Chemical Biology Symposium, to organize #ChemBioParis2025, in the heart of the City of Light. Oct 6-9, 2025.

Structural basis for selective inhibition of human GABA transporter GAT3 https://www.biorxiv.org/content/10.1101/2025.03.27.645797v1

Stellar line up for our protein design conference. Copenhagen, Sept 1-4, 2025. 10 days to abstract deadline. Get applying! benzon-foundation.dk/benzon-sympo...

⏰ Two weeks left to register for our Benzon Symposium on Protein structure prediction and design 🧶🧬🖥️ Meeting will take place in Copenhagen 🇩🇰 on Sept. 1–4, 2025, and will feature an amazing list of speakers 👨‍🔬👩‍🔬👩‍💻👨‍💻 Submit your application via: benzon-foundation.dk/benzon-sympo...

Our latest paper on the sodium leak channel NALCN complex is now online. We found that the neuronal SNARE proteins syntaxin 1A and SNAP25 inhibit sodium leak currents both in heterologous systems and in neurons! www.science.org/doi/10.1126/...

Labeling your axes and then explaining them slowly is perhaps the biggest bang for the buck you can get for making your slides more understandable.

Very grateful to have been able to attend #BPS2025! Big thanks to everyone involved in making this inspiring event possible! At the same time, the meeting was a stark reminder of how politics can interfere with science - and how cost 💲 is a major discriminator of who can and cannot attend!

Congratulations to the three Cole Award recipients at #BPS2025: Baron Chanda Dan Minor Crina Nimigean 👏👏👏👏👏👏

@renaeryan.bsky.social telling us who the three winners of the 2025 Cole Awards are! 🥳🥳🥳 #BPS2025

One more sleep to the @biophysicalsoc.bsky.social CRT Symposium on tomorrow morning bright and early! Join us in Petree Hall C at 8.30am.

The "Fluorescent Probes, Sensors and Fluorophores" starter pack got substantial additions worth a new look. Please raise you hand 👋 in the replies if you want to be added too. go.bsky.app/MtgJE4w

Just touched down in LA for #BPS2025 - excited to be here and looking forward to catching up with friends and colleagues!

Nothing like hearing about an exciting result from the lab after a long week of teaching!

Reminder that @europepmc.org is a mirror of Pubmed with better search and that it indexes *all* bioRxiv preprints (as well as ResearchSquare), not just the ones funded by NIH like chauvinist Pubmed

BF: Do not show everything! You have to be able to pitch the poster in less than a minute. Storytelling is important, as well as fundamental structure. #NWOPhysics

Excited to join Bluesky today! As an ion channel biophysicist, Professor at Duke Neurobiology, and Director of Graduate Studies I will be sharing my insights. Plus the occasional post of my private life. Please help me connect to my community by sharing this post.

Michael J. Shipston offers this #Perspective on the work of Belal et al. (2024) identifying that the atypical Na+ channel NALCN is a key determinant of native mouse anterior pituitary #endocrine cell physiology 💭 🔗 Read it here: https://buff.ly/3PClmTv

The Channels, Receptors & Transporters Subgroup of the @biophysicalsoc.bsky.social is excited to announce the final program for our 2025 Symposium. Please join us on Feb 15 to hear from @willowcoyote.bsky.social @drcontrexin.bsky.social @corrylab.bsky.social and others 👇Thanks to our sponsors!

Come to Copenhagen

Extraordinary talk is taking place next Tuesday 🤩 🪄Prof. Stephan Pless @plesslab.bsky.social is going to unravel the unconventional function of the sodium leak channel complex: "How NALCN is excited by other proteins more than by voltage?" 🚴 to connect: sodiumchannelseminars.org/Program-2024...

Thrilled to share the pre-print of my dissertation research on the bile acid-sensitive ion channel (BASIC)! 🥳

Want to come work with me? Short postdoc opportunity. Deadline tomorrow ⚡️ jobportal.ku.dk/videnskabeli...

De novo design of voltage-gated anion channels! www.biorxiv.org/content/10.1...