Antonios Pantazis lab (@antoniospantazis.bsky.social)

Out now at Nat Comm: "A rich conformational palette 🎨 underlies human CaV2.1-channel availability" 1. VSD-I activation triggers transmitter release 2. VSD-I conversion causes VDI & contributes to plasticity 3. CaV2.1 channels have several conformations at Vrest #neuroskyence #CACNA1A rdcu.be/ei0Tm

loading . . .

A rich conformational palette underlies human CaV2.1-channel availability Nature Communications - CaV2.1 channels are critical for neuronal communication. Here, authors showed they undergo electrically-evoked molecular movements which (1) eventually trigger... https://rdcu.be/ei0Tm

5 months ago