Christian A. Olsen
@christianaolsen.bsky.social
π€ 460
π₯ 209
π 15
Professor Drug Design and Pharmacology University of Copenhagen
Check out the write-up of our new publication in
#mBio
, where we profiled a large number auto-inducing peptide (AIP) signaling molecules from staphylococci.
@ucph.bsky.social
@bgless.bsky.social
@benjaminsb.bsky.social
news.ku.dk/all_news/202...
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Bacteria from cows show promising results in treating MRSA infections
New research from the University of Copenhagen shows that signaling molecules from a specific Staphylococcus bacterium can treat MRSA infections as effectively as antibiotics.
https://news.ku.dk/all_news/2025/07/bacteria-from-cows-show-promising-results-in-treating-mrsa-infections/
3 months ago
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The final version of this publication is now online:
journals.asm.org/doi/epdf/10....
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3 months ago
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We are hiring at the Department of Drug Design and Pharmacology. Check out these opportunities and consider becoming our new colleague at University of Copenhagen.
employment.ku.dk/faculty/?sho...
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164291 Associate Professor or Professor
https://employment.ku.dk/faculty/?show=164291
3 months ago
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reposted by
Christian A. Olsen
PlessLab
7 months ago
Our latest paper on the sodium leak channel NALCN complex is now online. We found that the neuronal SNARE proteins syntaxin 1A and SNAP25 inhibit sodium leak currents both in heterologous systems and in neurons!
www.science.org/doi/10.1126/...
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reposted by
Christian A. Olsen
Kresten Lindorff-Larsen
8 months ago
Chemical Solutions to Structural Biology symposium. Registration and abstract submission now open:
isbuc.ku.dk/chemical-sol...
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Check out the final version of this paper. Now out in
#JACS_Au
@pubs.acs.org
pubs.acs.org/doi/10.1021/...
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8 months ago
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Congratulations
@carlosmyruela.bsky.social
,
@beatfierz.bsky.social
and team on a great and important publication, providing new insights into SIRT7 activity
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8 months ago
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I am extremely happy to share this new
@biorxivpreprint.bsky.social
, which after a long wait updates our previous preprint. Thanks to main drivers
@bgless.bsky.social
and
@benjaminsb.bsky.social
as well as all involved colleagues and collaborators!
www.biorxiv.org/content/10.1...
8 months ago
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I am grateful to
@tnhansen.bsky.social
,
#Annika-Mergel
, and
#Marcos-San-Segundo
for co-authoring this piece!
@ucph.bsky.social
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8 months ago
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We have a new review article on recent applications of SuFEx chemistry in chemical biology now on-line at
#TrendsChem
@cellpress.bsky.social
Thanks to
@novo-nordisk.bsky.social
for funding our work.
authors.elsevier.com/a/1kWpX9CpcY...
Previously on ChemRxiv:
chemrxiv.org/engage/chemr...
8 months ago
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Thank you
#JACS-Au
for the selection
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8 months ago
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We have an exciting PhD position available. In collaboration with researchers
@scripps.edu
, we will investigate bacterial communication within the gut microbiome for potential health benefits, using chemical tools. Deadline 9 February, see π
candidate.hr-manager.net/ApplicationI...
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PhD fellowship in Chemical Microbiology at Department of Drug Design and Pharmacology
Faculty of Health and Medical Sciences, University of Copenhagen We are offering a three-year PhD fellowship in Chemical Microbiology commencing 1 May 2025
https://candidate.hr-manager.net/ApplicationInit.aspx/?cid=1307&departmentId=19218&ProjectId=163324&MediaId=5&SkipAdvertisement=false
9 months ago
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I am delighted to share that this paper is now published as an Editor's Choice article in JACS Au
@pubs.acs.org
pubs.acs.org/doi/10.1021/...
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9 months ago
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I am very happy to share that we have received support from
#Sygeforsikringen_danmark
to investigate bacterial crosstalk within the gut microbiota together with
#IngmerLab
@ucph.bsky.social
and
#GhadiriLab
@scripps.edu
sundhedsdonationer.dk/projekter/ba...
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Bakterielle signalmolekyler til brug for ΓΈget tarmsundhed - Sundhedsdonationer
https://sundhedsdonationer.dk/projekter/bakterielle-signalmolekyler-til-brug-for-oeget-tarmsundhed/
10 months ago
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New preprint
@chemrxiv.bsky.social
on discovery of macrocyclic inhibitors of HDAC11 with the Christian Heinis
#EPFL
Main contributors
@danieladankova.bsky.social
,
@alexanderln.bsky.social
,
@carlosmyruela.bsky.social
π @ERC_Research, @novonordiskfond, @DFF_raad for πΆ
chemrxiv.org/engage/chemr...
10 months ago
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In a new preprint
@chemrxiv.bsky.social
, work from
@bgless.bsky.social
and Sabrina Schmied investigate the mechanism of a rearrangement that can lead to peptide/protein backbone cleavage. Thanks to
#LEOFondet
for funding the project that led to this discovery.
chemrxiv.org/engage/chemr...
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Peptide Backbone Cleavage and trans-Amidation via Thioester-to-Imide Acyl Transfer
Cysteine thioesters are involved in a myriad of cen-tral biological transformations because of their unique reactivity. Despite their well-studied proper-ties, we discovered an unexpected trans-amidat...
https://chemrxiv.org/engage/chemrxiv/article-details/6750257a5a82cea2faf0c9bf
10 months ago
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