The work of Xingyu Liu @xingyuliu9595.bsky.social in collaboration with Wei Cai in Beat Fierz @beatfierz.bsky.social group @lcbm-epfl.bsky.social and Anne-Sophie Chauvin on peptide-cyanoarenes used as photocatalysts is now accepted in @angewandtechemie.bsky.social ! doi.org/10.1002/anie...

Our new study of chromatin ubiquitylation by variant PRC1 on the single-molecule scale: We visualize directly how vPRC1 ubiquitylates neighboring nucleosomes during a single binding event, showing a potential mechanism how H2Aub domains are established. www.science.org/doi/10.1126/...

I am very happy to share that I was awarded a PhD fellowship from the Boehringer Ingelheim Fonds (BIF) for my project about nucleosome depletion in @lcbm-epfl.bsky.social with @beatfierz.bsky.social. Looking forward to joining the BIF community 😊🥳

#SIRT7 is a histone deacetylase with highly specific activity on #chromatin substrates. We just published mechanism-based #cryoEM structures of #SIRT7 on nucleosomes to understand its activity 👇 www.nature.com/articles/s41... (1/8) #ChemBio #ChemSky

Don’t miss tomorrow's in-person #chembio seminar by Prof. Dr. Nina Hartrampf @ninahartrampf.bsky.social 👉 "New Methods for the Chemical Synthesis of Post-Translationally Modified Peptides and Proteins" ⏱️🇨🇭16:15 › 17:15 📢 bit.ly/3MOjVjy

Always nice to share the ideas together! Many THX to who show interest and ideas in our project 🙏 If interested in TF target search, feel free to contact us 📧 @beatfierz.bsky.social @davidsuter.bsky.social THX to the EMBL travel grant for me to attend such great conference #EMBLOmics

🎖️ Yesterday PhD #Benjamin won a presentation price at the LS2 sub-section meeting – nice recognition for his careful #DyeCycling work! 🟢🔴🧬 Many thanks to @beatfierz.bsky.social, #KatjaOdening & all for organizing! Also great to meet the 🇨🇭 community, #SimonScheuring, #ChanCao, #WayneYang ...👌

Are you looking for a PhD position in peptide synthesis, automation, and computational analysis? 🧪 💊💻 We have an open position for a collaborative PhD thesis (with Novo Nordisk). For more details, please see: jobs.uzh.ch/job-vacancie... ⏰ Application deadline = November 15

Want to see how PRC1 writes the Polycomb ubiquitin mark on chromatin, in real-time? Check out our latest preprint, done all by Alexandra Teslenko at ISIC EPFL, a tour-de-force of single-molecule enzymology! www.biorxiv.org/content/10.1...

Lots of movement on bsky, it’s getting lively!

Want to see how PRC1 writes the Polycomb ubiquitin mark on chromatin, in real-time? Check out our latest preprint, done all by Alexandra Teslenko at ISIC EPFL, a tour-de-force of single-molecule enzymology! www.biorxiv.org/content/10.1...

Check out the new review from @carlosmyruela.bsky.social on the using synthetic chromatin to investigate the function of histone deacylases! doi.org/10.1042/BST2...

Impressions from the LCBM Xmas party.!Happy holidays!!! 🎄🎁🎅🏽

Check out our work on centro-chromatin, where CENP-A and CENP-B collaborate to generate a dynamic chromatin state! A great collaboration between Nikolina Sekulic’s lab & us, and the labs of Mario Halic and Tatsuo Fukagawa. Congrats Harsh and Ahmad! www.nature.com/articles/s41...

The work of Xingyuu Liu and Jerome Waser, in collaboration with us and the Radenovic lab and funded within project SeleCHEM (ERC), on the gold catalyzed macrocyclization of peptide-EBXs to make fluorescent macrocycles is now in JACS! pubs.acs.org/doi/10.1021/...

Are you a junior scientist 🏋️ in 🇨🇭#chembio, 🔎opportunities for lasting professional relationships & showcase your research? 🧪🔬 👉🏻 ask your PI to join the SNE #ChemBio network! 👉🏻 submit your request bit.ly/3QuphmC #ChemicalBiology #Networking #ChemBio

Another exciting position at EPFL in Life Science Engineering, spanning the disciplines of: synthetic, systems and computational biology, cellular and tissue engineering, biomaterials, functional genomics, proteomics and metabolomics! Find the details here: www.epfl.ch/about/workin...

Congratulations to PhD student Arthur Despois for his poster prize at the joint posters exhibition of SCGC-EDCH! actu.epfl.ch/news/best-po...

We are hiring! We look for Postdocs in the field of biophysics / chemical biology of gene regulation within a context of a SNSF Advanced Grant starting in 2024! More details here: www.epfl.ch/schools/sb/r...

Are you developing new biosynthesis and/or green chemistry approaches? Here is a tenure track faculty position that might be of interest to you! There is less than a month left to apply for this position (deadline Oct 15)! So, apply here and join us at EPFL! www.epfl.ch/about/workin...