Nat. Photonics🔬 Meet 3I-SIM! Instead of stripes, we use 3-beam to generate 2D hex pattern for simultaneous 2D SIM modulation, with >100,000 frames, 13 h neuronal cell movies, ER–lipid-droplet kiss-n-run and millisecond tango. All hard&software open. doi.org/10.1038/s415... @pku1898.bsky.social

C²SD-ISM combines physical defocus rejection (spinning disk) with adaptive algorithm (DPA-PR), breaking depth limits in tissue super-resolution (↑180 μm), enhances fidelity (92% linear correlation), and supports high-throughput imaging. doi.org/10.1038/s413... Github: github.com/Chauncey-Leu....

mScarlet3-H (aka mYongHong) is on the cover of Nature Methods! All plasmids are available for free from WeKwikGene wekwikgene.wllsb.edu.cn/publications...

Congratulations to Suyi Zhong, Wei Ren, Ziyi Yang, and Hongyu Wang!

I am very glad to see that our PolarSIM helps the leading scientists to observe richer dynamics and get more discovery! Congratulations to Zhixing team for this brand new palette of fluorescent dyes named after BeiDa! www.nature.com/articles/s41... @pku1898.bsky.social @zhixingchen2.bsky.social

Here come our new palette of fluorescent dyes. The BD dyes endeaves to balance glowy brightness, robust photostability, and biocompatibility. Let's boost 4D dynamic super-resolution imaging!!! www.nature.com/articles/s41... @spirochrome.com

I am very glad to see that our PolarSIM helps the leading scientists to observe richer dynamics and get more discovery! Congratulations to Zhixing team for this brand new palette of fluorescent dyes named after BeiDa! www.nature.com/articles/s41... @pku1898.bsky.social @zhixingchen2.bsky.social

I am very glad to see that our PolarSIM helps the leading scientists to observe richer dynamics and get more discovery! Congratulations to Zhixing team for this brand new palette of fluorescent dyes named after BeiDa! @pku1898.bsky.social @zhixingchen2.bsky.social

I am very glad to see that our PolarSIM helps the leading scientists to observe richer dynamics and get more discovery! Congratulations to Zhixing team for this brand new palette of fluorescent dyes named after BeiDa! @pku1898.bsky.social @zhixingchen2.bsky.social

Thrilled to introduce our Cover review: High-spatiotemporal-resolution structured illumination microscopy: principles, instrumentation, and applications dx.doi.org/10.3788/PI.2...

Unlock the secrets of cellular dynamics with high-spatiotemporal-resolution structured illumination microscopy! Our latest review explores the principles, instrumentation, and applications of SIM&ISM in live-cell imaging. #Microscopy #SuperResolution #CellBiology dx.doi.org/10.3788/PI.2...

Seeing Deeper, Clearer than Ever!🔬Prof. Xi Peng’s team from #PKU College of Future Technology introduces Dark Sectioning in Nature Methods—a breakthrough for fluorescence microscopy! A peek into the future of imaging: www.nature.com/articles/s41... #PKUResearch #AcademicSky @natmethods.nature.com

For a quick summary of the paper, read the Research Briefing here: www.nature.com/articles/s41...

Nice work! We integrated this dark-sectioning method into our FlexSIM pipeline (github.com/esoubies/Fle...) as an additional option for handling out-of-focus signal. It works remarkably well!

In particular, it handles out-of-focus regions more effectively than traditional OTF attenuation.

Our groundbreaking Dark Sectioning technique is now published in Nature Methods! 🎉 It supercharges existing imaging systems: 🔬 Widefield → Confocal 🔬 Single-photon → Multiphoton 🔬 2D-SIM → 3D-SIM Now integrated in Airy PolarSIM and #FlexSIM! doi.org/10.1038/s415... #Microscopy #Fluorescence