Ellie Pursey
@elliepursey.bsky.social
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Drawing, writing. Scientist of microbial genomes, phage enthusiast.
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Ellie Pursey
Ele Willoughby
13 days ago
Day 11
#SciArtSeptember
prompt venomous: my linocut of a Portuguese Man oā War floating at the surface of the sea. š§Ŗš” These are beautiful but deadly creatures, also known as bluebottles, resemble jellyfish but are actually colonial organisms called siphonophores. They are made up of many š§µ
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10 - Tawny My participation in
#SciArtSeptember
has been a bit sporadic - chronic illness is messing with me. But here is one of my favourite animals, the Tawny Owl. Love to hear them calling to each other š¤
13 days ago
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5 - Corridor
#SciArtSeptember
A pastel sketch of a landscape based on a photo I took last year in the Alps. This region is rich in biodiversity and mountains can form important corridors for wildlife to travel.
18 days ago
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4 - Riverbank Sketch of a grey heron with a fish in pastel pencil
#SciArtSeptember
19 days ago
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3 - Jewel Missed a couple of days of
#SciArtSeptember
but here is my attempt to join in with today's prompt. This is a pastel pencil drawing of a jewel beetle.
20 days ago
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Not micro, but still nature š
7 months ago
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Bacterial cells
7 months ago
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Bacteriophages, my muse
7 months ago
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Ellie Pursey
Erik van Nimwegen
8 months ago
What do bacterial cells do when they run out of nutrients? Although most bacterial studies focus on cells in exponentially growing states, in the wild bacteria likely spend most of their time slowly starving to death. 1/n
www.biorxiv.org/content/10.1...
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E. coli prepares for starvation by dramatically remodeling its proteome in the first hours after loss of nutrients
It is widely believed that due to nutrient limitations in natural environments, bacteria spend most of their life in non-growing states. However, very little is known about how bacteria change their p...
https://www.biorxiv.org/content/10.1101/2024.02.29.582700v2
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Professor John R. Hutchinson
8 months ago
I guess I hadn't posted this yet and didn't even know it had come out-- I was interviewed for (and co-wrote w/Daniel Rabosky) a Trends in Ecology & Evolution "TrendsTalk" article on "Disability in ecology and evolution" --
www.cell.com/trends/ecolo...
#DisabledInSTEM
#academicchatter
#academia
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Disability in ecology and evolution
In this TrendsTalk series āDisability in ecology and evolutionā in Trends in Ecology & Evolution, we will be hearing from people about their experiences being disabled or having a chronic condition an...
https://www.cell.com/trends/ecology-evolution/fulltext/S0169-5347(24)00283-0
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Anna Vlasits
about 2 years ago
Many people take "non-traditional" career paths in academia. My Leading Edge colleagues and I did! We wrote for PLOS Biology about how non-linear careers are increasingly common, but funding agencies and search committees penalize these paths.
journals.plos.org/plosbiology/...
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Supporting nonlinear careers to diversify science
Those who follow non-linear career trajectories often face disadvantages in academia. This Perspective looks at why individuals might choose non-linear careers and how these benefit diversity in scien...
https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002291
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Liam Langley
10 months ago
New paper alert! Really excited to see this work from a postdoc with Steve Votier
@heriotwattuni.bsky.social
published in Ecology & Evolution! In it, we use existing bio-logging data to study competition and facilitation in foraging gannets. Link to paper here:
dx.doi.org/10.1002/ece3...
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Competition and Facilitation Influence Central Place Foraging Ecology in a Colonial Marine Predator
Analysis of combined deployments of GPS loggers with cameras or temperatureādepth recorders reveals that despite experiencing intraspecific competition for food, northern gannets engage in dynamic, c...
http://dx.doi.org/10.1002/ece3.70494
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Ellie Pursey
Meaghan Castledine
10 months ago
Hello new phage phollowers! I am shamelessly self-promoting mine and Angus Buckling's relatively new review "Critically evaluating the relative importance of phage in shaping microbial community composition"
www.cell.com/trends/micro...
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Critically evaluating the relative importance of phage in shaping microbial community composition
The ubiquity of bacteriophages (phages) and the major evolutionary and ecological impacts they can have on their microbial hosts has resulted in phages often cited as key drivers shaping microbial com...
https://www.cell.com/trends/microbiology/fulltext/S0966-842X(24)00057-X?dgcid=raven_jbs_aip_email
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Eduardo Rocha
11 months ago
Our paper on identifying novel origins of transfer by conjugation is out! One can now expand the known oriTs from 1% to 80% in species like Acinetobacter baumannii. This contributes to unravel hitcher plasmid mobility beyond model elements.
#microsky
www.nature.com/articles/s41...
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Expanding the diversity of origin of transfer-containing sequences in mobilizable plasmids - Nature Microbiology
Characterization of known plasmid oriT features facilitates identification of 21 oriT-containing sequence families which, alongside candidate sequence validation, expands our understanding of plasmid ...
https://www.nature.com/articles/s41564-024-01844-1
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Xabier Simón MartĆnez de GoƱi
11 months ago
š¢Calling all researchers! We are studying what makes a great (or not-so-great) supervisor from the perspective of PhD students and postdocs. Our goal? To improve academic mentorship and research environments. Got 5-10 minutes? Take the survey!āļø
forms.gle/WT9GoiaHxypX...
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Labelling my scientific supervisor: A genuine leader or just a big jerk?
Thank you for taking part in this survey. The aim of this survey is to understand which characteristics make a scientific supervisor supportive and constructive or, conversely, detrimental to the grow...
https://forms.gle/WT9GoiaHxypX6GGB6
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Ellie Pursey
Ellinor Alseth
11 months ago
People at work seem to be enjoying my new sign (but are yet to feed the postdoc...) š§Ŗ
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Ellie Pursey
Stephen Curry
11 months ago
Rage, rage against the dying of the light. But donāt give into despair. For those of us who cling to liberal values, moral principles, and the dignity of all people, there is much work to do.
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bioRxiv Microbiology
11 months ago
TIR signaling activates caspase-like immunity in bacteria https://www.biorxiv.org/content/10.1101/2024.10.24.620036v1
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TIR signaling activates caspase-like immunity in bacteria https://www.biorxiv.org/content/10.1101/2024.10.24.620036v1
Proteases of the caspase family, as well as Toll/Interleukin-1 Receptor (TIR)-domain proteins, have
https://www.biorxiv.org/content/10.1101/2024.10.24.620036v1
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c0nc0rdance
12 months ago
"Women are less likely to be named authors on any given document in all fields and at all career stages." "Women are credited less in science than men" Nature 608, p 135ā145 (2022) Link:
www.nature.com/articles/s41...
add a skeleton here at some point
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Alice Maestri
about 1 year ago
I'm so happy to see the main part of my PhD work published in Cell Host & Microbe! We discover and characterise MADS (Methylation Associated Defense System) in its native host, a clinical isolate of šš“š¦š¶š„š°š®š°šÆš¢š“ š¢š¦š³š¶šØšŖšÆš°š“š¢ strain SMC4386
www.cell.com/cell-host-mi...
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The bacterial defense system MADS interacts with CRISPR-Cas to limit phage infection and escape
The coevolution between bacteria and mobile genetic elements has resulted in a large diversity of defense systems. Maestri etĀ al. describe an innate immune system, MADS (methylation-associated defense...
https://www.cell.com/cell-host-microbe/fulltext/S1931-3128(24)00264-6
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Liam Langley
over 1 year ago
Really proud of our new guide to processing and exploring animal tracking data in R which has just been published in
@animalecology.bsky.social
! If you work with animal tracking data or have a student that does then please read and share! Lots of useful code and a shiny app for data vis!
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Tatiana Dimitriu
over 1 year ago
I'm recruiting a Research Technician to work on plasmid transmission and antimicrobial resistance in St Andrews, to start in October. Deadline for applications is 19 June. Please share!
www.vacancies.st-andrews.ac.uk/Vacancies/W/...
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Research Assistant - AR2992DM
https://www.vacancies.st-andrews.ac.uk/Vacancies/W/3844/0/430642/889/research-assistant-ar2992dm
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Ellie Pursey
Prof Chris Jackson
over 1 year ago
I often think about this in the context of leaving my 17-year long academic career...
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Jorge Moura de Sousa
over 1 year ago
New paper from the lab, the mysteries involving the genetic elements that move by being mobilized by other MGEs. Hitcher Genetic Elements are distinctive, ancient and diverse.
ecoevorxiv.org/repository/v...
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Hijackers, hitchhikers, or co-drivers? The mysteries of microbial mobilizable genetic elements
https://ecoevorxiv.org/repository/view/7042/
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Ellie Pursey
Ellinor Alseth
over 1 year ago
Our paper on "The impact of phage and phage resistance on microbial community dynamics" is finally out in PLOS Biology! What a journey it's been to get here, and I couldn't have done it without my fab co-authors
journals.plos.org/plosbiology/...
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The impact of phage and phage resistance on microbial community dynamics
Phages shape the microbial world. This study uses an evolution experiment to explore how phage impact the structure and dynamics of a four-species bacterial community, finding that phage enables compe...
https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002346
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Ellie Pursey
Gemma C. Atkinson
over 1 year ago
Now we have a bioinformatics PhD position In my group in Lund to work on the same fun
#phage
defence project! Read more and apply here:
lu.varbi.com/en/what:job/...
deadline March 5th
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Gemma C. Atkinson
over 1 year ago
Join the fun! And stay tuned for a bioinformatics PhD position to work on the same project!
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Eduardo Rocha
over 1 year ago
New from the lab. We were stuck studying plasmid mobility because we ignored most origins of transfer by conjugation. Using the occurrences of known oriT, we developed a method to find novel unrelated families. Works well. We now cover most conjugative plasmids of E coli, K pneumo & A baumannii.
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Give a postdoc a compliment today, we need them to fight off the existential crises š
over 1 year ago
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Gemma C. Atkinson
over 1 year ago
LU-Fold is now available to researchers across Sweden! Curious about how high-throughput
#AlphaFold
folding of monomers and co-folding of complexes can help your research? Get in touch for a chat!
medicine.lu.se/lu-fold
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So it turns out no matter how much time you spend organising your reading list, you will eventually still have to actually read something?!
over 1 year ago
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Ellie Pursey
Liam Langley
over 1 year ago
Just published a short blogpost briefly summarising my autumn birding in Sweden and looking forward to a year of local patch birding in 2024 -
agullloverstravels.wordpress.com/2023/12/30/l...
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Looking Forward
As I reside in that curious period between Christmas and New Year where time seems to lose its linear progression and the days blend together, Iāve found myself feeling reflective. On a personal lev...
https://agullloverstravels.wordpress.com/2023/12/30/looking-forward/
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Ellie Pursey
Eduardo Rocha
almost 2 years ago
Your student has my sympathy (hopefully he/she doesn't need it). Got a lot of those "this is just bioinformatics". Sad to see it still in 2023.
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Ellie Pursey
Duncan Ng
almost 2 years ago
Guess the UK doesnāt want any postdocs or ECRs anymore š«
www.bbc.co.uk/news/live/uk...
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Salary needed for skilled foreign workers rises by a third to £38,700 - BBC News
The home secretary is expected to say employers will only be able to hire from abroad when paying higher salaries.
https://www.bbc.co.uk/news/live/uk-politics-67612152?ns_mchannel=social&ns_source=twitter&ns_campaign=bbc_live&ns_linkname=656df6b96868a4009ac439dc%26Minimum%20salary%20needed%20to%20get%20UK%20worker%20visa%20rises%262023-12-04T16%3A40%3A46.629Z&ns_fee=0&pinned_post_locator=urn:asset:8285f679-74f6-40d4-9114-739e8d8f7f59&pinned_post_asset_id=656df6b96868a4009ac439dc&pinned_post_type=share
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Ellie Pursey
Tatiana Dimitriu
almost 2 years ago
Funded 4-year PhD opportunity with me based in St Andrews @SchoolofBiology. One of two projects on mobile genetic elements, antibiotics and defence systems.
www.findaphd.com/phds/project...
www.findaphd.com/phds/project...
Please share & pass on to anyone interested!
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Lund in the snow, the moon is a paid actor š
almost 2 years ago
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Ellinor Alseth
almost 2 years ago
A very short thread on how I imagine the different bacteria I work with as humans. Starting with E. coli:
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Ellie Pursey
MDM lab
almost 2 years ago
š»š§« New preprint: How accurately can we predict diverse phage bacteria-interactions from their genomes only ? We created a matrix of >38k phage-bacteria interactions to find out (=> AUROC 86%) & used our predictions to recommend tailored phage cocktails.
www.biorxiv.org/content/10.1...
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Ellie Pursey
purr.in.ink
almost 2 years ago
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Lilly Cummins
almost 2 years ago
New paper! š£ We looked at the prevalence of type VI secretion systems (T6SSs) across E. coli and characterised the systems present in renowned MDR lineages ST410 and ST131
www.microbiologyresearch.org/content/jour...
(1/2)
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Ellie Pursey
Rachel M. Wheatley
almost 2 years ago
š¦ New preprint š¦ Really happy to see this up on bioRxiv - my 1st as senior author & Linaās 1st as first author š a double whammy. š Antibiotic resistance alters the ability of Pseudomonas aeruginosa to invade the respiratory microbiome (1/n)
www.biorxiv.org/content/10.1...
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Antibiotic resistance alters the ability of Pseudomonas aeruginosa to invade the respiratory microbi...
bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution
https://www.biorxiv.org/content/10.1101/2023.11.14.567137v1
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I'm a postdoc but very regularly get asked if I'm a masters student by other academics. This seems to happen regularly to other women postdocs I know too - it feels gendered?
almost 2 years ago
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Ellie Pursey
Ellinor Alseth
almost 2 years ago
At least it's just delayed! When I lived in Cornwall the train occasionally caught fire or they'd somehow lost it...
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Unreasonably excited to have a new giant notebook and coloured pens for all my science ramblings
almost 2 years ago
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Liam Langley
almost 2 years ago
Unexpected morning jaunt to Borgarsparken to twitch the stunning Pallasās Warbler found by Petter Olsson. Despite blustery conditions it gave excellent views and even called several times! A species that always feels like a lifer no matter how many you see and only a 25 min walk from home!
#birding
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Ellie Pursey
Eduardo Rocha
almost 2 years ago
New preprint on the evolution of natural transformation. We measured transformation rates in 100s of
#Acinetobacter
baumannii &
#Legionella
pneumophila. Key arising question: why are so many strains non-transformable if the many recent transitions to non-transformability seem deleterious? 1/4
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Intragenomic conflicts with plasmids and chromosomal mobile genetic elements drive the evolution of ...
bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution
https://www.biorxiv.org/content/10.1101/2023.11.06.565790v1
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Ellie Pursey
Stephan Gruber
almost 2 years ago
First preprint š¢ on bsky: New work on the Wadjet defence system by
@roisnehamelinf.bsky.social
&
@drhonsworth.bsky.social
revealing beautiful & exciting structures of JET on plasmid DNA. With loop extrusion, obstacles, DNA bending, kinking, cleavage š¦ š§« š§Ŗ
t.co/RaO7IO3zDk
Ā With help from @DCI_Lausanne
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Prof Chris Jackson
almost 2 years ago
Ermā¦this aināt cool
inews.co.uk/news/governm...
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Government prepared secret dossier on academicās posts on BLM, 'militant leftism', Israel war
'Highly disturbing' revelations raise serious questions about free speech, says University and College Union
https://inews.co.uk/news/government-prepared-secret-dossier-academics-blm-2730858
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Danna Gifford
almost 2 years ago
š£ Paper: We show that mutators can drive the evolution of multi-resistance to antibiotics, in cases where purely wild type populations can't This came out earlier this year while the other place was imploding But it's a story I'm proud of for many reasons... 1/n
journals.plos.org/plosgenetics...
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Mutators can drive the evolution of multi-resistance to antibiotics
Author summary The global rise in antimicrobial resistance means we urgently need new approaches that halt its spread. Combination therapy, using multiple antibiotics as one treatment, proposes to do ...
https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1010791
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Izzy Jayasinghe
almost 2 years ago
A few things that I've needed to get off my chest for some time now. š§Ŗ š
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Remembering the role of luck and privilege in academic achievement
This week I woke up to the announcement by my alma materāāāThe University of Aucklandāāāof its 2023 cohort of ā40 under 40ā that listed meā¦
https://medium.com/@i.jayasinghe/remembering-the-role-of-luck-and-privilege-in-academic-achievement-7b643b3bd760
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