Almost 10 years ago - "All biology is computational biology" (2017) - journals.plos.org/plosbiology/... Today - "The total eclipse of bioinformatics: From disruption to convention, and a gentle warning" (2026) - journals.plos.org/ploscompbiol...

Highly under-rated context management for Claude Code ( github.com/lllyasviel/VCC ) and Pi ( github.com/sting8k/pi-vcc ), esp. great with local models. Searchable context is presented as a "UI View" with code chunks replaced with one-line summary pointers like "* Write 'src/pets.py' (.txt:40-62)".

A beautiful wooden model of pancreatic trypsin inhibitor (5PTI, Wlodawer et al, 1984). From: pmc.ncbi.nlm.nih.gov/articles/PMC...

Big milestone for the AI Protein Design Program last November: our first AI binder design workshop! Proud of the team and grateful to @kmichie.bsky.social for her amazing talk. This is just the beginning… excited for what’s next! #AI #ProteinDesign #AIPDP

This is the first time in a long time I've tried an alternative Python notebook implementation and instantly known I'll switch to using it: docs.marimo.io Batteries included - variable browser, cell dependency tree for automatic reactive updates, a notebook-aware AI chat right there in the sidebar.