Quantitative Biosciences Institute, UCSF
@qbi-ucsf.bsky.social
📤 76
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Transforming our understanding of biology and disease through collaborative, quantitative research.
We're pleased to welcome Andy Kilianski
@andykilianski.bsky.social
as QBI's Chief Science & Technology Officer. Learn more about Andy's background and the role he'll play as QBI continues to expand its translational science and technology initiatives:
go.shr.lc/4v1N5zK
about 23 hours ago
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On June 10, Raphaël of
@pasteur.fr
will talk about how phages adapt to new hosts using DNA-based “variation systems” that rapidly reshuffle key proteins involved in host recognition...and more! Hope you can join us. Learn more & register:
qbi.ucsf.edu/events/semin...
3 days ago
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One week to go until QBI, UAlberta, & Gladstone bring together researchers across fields for this dynamic symposium. Trainees: join the Trainee Collaboration Prize. Build project ideas, connect with collaborators, and compete for a $500 prize!
qbi.ucsf.edu/events/qbi-u...
15 days ago
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A new Cell Host & Microbe study from QBI, Gladstone, and Icahn Mount Sinai maps virus–host interactions in humans & bats. A single change in SARS-CoV-2 Orf9b alters immune targeting across species, helping explain why bats tolerate viruses humans don’t. Learn more:
qbi.ucsf.edu/qbi-highligh...
23 days ago
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We’re excited to welcome John Young as QBI’s Chief Strategy Officer. With experience across pharma R&D,
#InfectiousDisease
, pandemic preparedness, & public-private partnerships, John will help advance QBI’s mission to move discoveries closer to patients. Read more here:
go.shr.lc/4dkGVmK
24 days ago
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Join the next Pre-Hackathon Meet & Greet Mixer at UC Santa Cruz next week! Details and sign up:
qbi.ucsf.edu/events/hacka...
add a skeleton here at some point
28 days ago
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QBI UCSF, UAlberta & Gladstone present: a joint symposium on May 29! We will explore how molecular and computational approaches are reshaping neuro-inflammation research. There will be posters + a trainee collaboration initiative. Learn more and register:
qbi.ucsf.edu/events/qbi-u...
about 1 month ago
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Looking for your next big challenge? Join our Hackathon 2026 Pre-Hackathon Mixers and connect before the main event in June. Meet collaborators, pitch ideas, and start building your team early. April 27 — UC Berkeley May 14 — UC Santa Cruz June 11 — UCSF
qbi.ucsf.edu/hackathon-de...
about 1 month ago
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Join us on April 23 for a seminar with Dr. Christopher Overall, who will discuss how SARS-CoV-2 uses key enzymes to disable defenses, spread between cells, and avoid detection -- insights that could shape future antivirals. More details:
qbi.ucsf.edu/events/semin...
about 2 months ago
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A new Cell paper authored by Ujjwal Rathore, Eli Dugan, and colleagues reveals a comprehensive map of how HIV interacts with human proteins in primary immune cells, opening exciting new doors for HIV drug discovery. Learn more:
qbi.ucsf.edu/qbi-highligh...
about 2 months ago
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Join us April 22 for a seminar with Janet Iwasa, a leader in 3D molecular animation at University of Utah. From research to storytelling, her work transforms how we understand cells - and even how scientists build hypotheses. See you there! Learn more & register:
qbi.ucsf.edu/events/semin...
about 2 months ago
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The start time for the April 13 QBI Seminar featuring Mehdi Bouhaddou has been changed. New time: April 13, 2026, at 1:00 PM (previously 2:00 PM). Event details:
qbi.ucsf.edu/events/semin...
We appreciate your understanding and hope you can still join us.
add a skeleton here at some point
about 2 months ago
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Join us on April 14 for a Systems Biology for Infectious Diseases Workshop! Learn network biology, multi-omics & computational modeling through influenza, coronavirus & antimicrobial resistance case studies. Register by April 10:
qbi.ucsf.edu/events/sysbi...
about 2 months ago
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How do cells respond to their environment? Mehdi Bouhaddou provides a fascinating cross-disciplinary perspective on biology, disease, and adaptation! Join us on April 13 to hear about it:
qbi.ucsf.edu/events/semin...
2 months ago
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10 years ago, the Quantitative Biosciences Institute was established at UCSF.✨ Revisit the original announcement from 2016:
www.ucsf.edu/news/2016/03...
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Archive: UCSF Establishes Quantitative Biosciences Institute
UCSF announced the establishment of the Quantitative Biosciences Institute (QBI), to drive forward the application of computation, mathematics, and statistics toward a deeper understanding of complex ...
https://www.ucsf.edu/news/2016/03/402156/ucsf-establishes-quantitative-biosciences-institute
3 months ago
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Excited to highlight new work from Rezo Therapeutics. Their collaboration with NVIDIA advances AI approaches to predict higher order protein complexes and uncover disease relevant interactions. The work builds on research from the lab of QBI Director Nevan Krogan.
rezotx.com/predicting-a...
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Predicting and Verifying Novel Higher-Order Protein Complexes In Silico With NVIDIA | Rezo
https://rezotx.com/predicting-and-verifying-novel-higher-order-protein-complexes-in-silico-with-nvidia-2/
3 months ago
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As the top-funded unit within the School of Pharmacy, QBI proudly supports UCSF’s mission to lead in research excellence and help drive breakthroughs from the lab to real-world therapies.
pharmacy.ucsf.edu/news/2026/02...
3 months ago
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On March 13, QBI welcomes two leaders from
@genentech.bsky.social
for a seminar: Jennie Lill & Tess Branon! "Deciphering Disease Dynamics, Supporting Drug Discovery, & Empowering ML with transformative proteomic technologies" Register to join us:
qbi.ucsf.edu/seminar-jenn...
3 months ago
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Join us for the next Infectious Diseases & Human Health Symposium by
@gladstoneinst.bsky.social
and QBI: "Sex Differences in Immunity and Diseases" on February 27! Learn more & register:
qbi.ucsf.edu/sex-differen...
3 months ago
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Join us on Feb 6 at UCSF for a talk by Christian Freund of
@freieuniversitaet.bsky.social
on Dynamic States in the Peptide Exchange of MHC Class I Molecules. From immune signaling to neurobiology ... plus great science, refreshments & community. Don’t miss it! Register:
qbi.ucsf.edu/christianfre...
4 months ago
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Check out an overview of our HIV Accessory and Regulatory Complexes Center’s systems biology approach to HIV discovery, featured in a UCSF School of pharmacy article with commentary from HARC program manager Zelda Love!
pharmacy.ucsf.edu/news/2026/01...
4 months ago
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Join us for an evening exploring how science is reshaping our understanding of the brain. ✨ Flash talk by Dr. Matthew State ✨ Conversation with journalist Victoria Colliver ✨ Open audience Q&A The Night of Science-making science relevant and deeply human. Register:
qbi.ucsf.edu/night-of-sci...
5 months ago
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Kick off 2026 with us! Meet Søren Brunak of the University of Copenhagen on Jan 8 at UCSF. He turns massive biological datasets into insights advancing medicine, biotechnology, and health. Join us in hearing from a leading voice in the field. Learn more & register:
qbi.ucsf.edu/seminar-brunak
5 months ago
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Looking back on 2025, we’re proud to reflect on the milestones, discoveries, and collaborations that made the year remarkable. Explore our timeline for some key moments from last year and join us as we continue the journey in 2026!
qbi.ucsf.edu/YearInReview...
5 months ago
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We’re welcoming Kevin Lou as a QBI Fellow! In his Q&A, he shares what inspired his journey into chemical biology, why QBI is the right place to pursue his vision, and how quantitative approaches are shaping the future of drug discovery. Read more:
qbi.ucsf.edu/kevin-lou-qb...
6 months ago
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APOE4, the strongest genetic risk for Alzheimer’s, disrupts the recycling centers of nerve cells, laying the foundation for toxic protein accumulation. A new study led by Einar Krogsaeter & Danielle Swaney sheds light on early cellular stress in AD. Read more:
www.tandfonline.com/doi/full/10....
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Lysosomal proteomics reveals mechanisms of neuronal APOE4-associated lysosomal dysfunction
APOE4 is the primary risk factor for Alzheimer disease (AD). Early AD pathological events first affect the neuronal endolysosomal system, which in turn causes neuronal protein aggregation and cell ...
https://www.tandfonline.com/doi/full/10.1080/15548627.2025.2576613?src=#abstract
7 months ago
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What happens when a chromosome breaks & how do cells put it back together? Jim Haber
@brandeisuniversity.bsky.social
will be at UCSF next week to share how scientists learned to watch DNA repair in real time & what that reveals about how cells maintain genetic stability.
qbi.ucsf.edu/seminar-haber
7 months ago
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Join us on November 13 for a seminar with Dr. Rafael Couñago of UNC on leveraging AI models to accelerate chemical probe discovery for Target 2035! Learn more & register for his talk:
qbi.ucsf.edu/seminar-coun...
7 months ago
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How does AI meet molecular structure to reveal the roots of health & disease? Join us for a QBI seminar with Dr. Arun Prasad Pandurangan of University of Cambridge on November 12 at UCSF Mission Bay! Learn more & register:
qbi.ucsf.edu/seminar-pand...
7 months ago
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How do cells control what enters and exits the nucleus? A study maps the nuclear pore complex in unprecedented detail, solving a decades-old mystery and offering insights into cancer, Alzheimer’s, and ALS:
www.pnas.org/doi/10.1073/...
7 months ago
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We look forward to welcoming Dr.
@andykilianski.bsky.social
, Program Manager at ARPA-H for a seminar hosted by James Fraser. Learn about how ARPA-H is investing in bold, transformative research to shape the future of health in the United States:
qbi.ucsf.edu/seminar-kili...
7 months ago
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AI is powering new frontiers in drug discovery, but success still depends on good data and biological insight. This
@cenmag.bsky.social
piece features our director, Nevan Krogan, among voices exploring the real promise and pitfalls of AI in biomedicine.
cen.acs.org/physical-che...
8 months ago
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Join us for the next Infectious Diseases & Human Health Mini-Symposium by
@gladstoneinst.bsky.social
and QBI: “Viral Landscapes: How to Comprehensively Monitor Evolutionary Trajectories" on 9/23. Learn more & register:
qbi.ucsf.edu/givi-mini-sy...
9 months ago
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New QCRG-AViDD study: SARS-CoV protein Orf9b shape-shifts to block our immune defenses by binding to mitochondria’s Tom70. Lipids & mutations tweak how efficiently it works -revealing new insights into coronavirus immune evasion. Learn more:
doi.org/10.7554/eLif...
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Coupled equilibria of dimerization and lipid binding modulate SARS Cov 2 Orf9b interactions and interferon response
Lipid binding stabilizes the SARS-CoV-2 Orf9b homodimer, slowing its conversion to the Tom70-binding monomeric form and modulating interferon suppression.
https://doi.org/10.7554/eLife.106484.3
9 months ago
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The HARC Center supports scientists through Mentored Scientist and Collaborative Developmental Awards, fostering HIV research and training opportunities. Check out this year’s awardees and the projects they’re working on! 🔬✨https://bit.ly/HARCawards2025
9 months ago
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In this QBI TV Fireside Chat, Amber Smith sits down with Zelda Love to share insights from her team’s new cryo-EM structure of the HIV-1 Rev/RRE/CRM1/Ran complex. Watch the episode & read the study:
qbi.ucsf.edu/Smith-Love-Q...
9 months ago
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Speaker lineup announced & registration now open! Join us for a chance to connect, celebrate, and support the next generation of researchers at the QBI Internship Symposium on 8/19.
qbi.ucsf.edu/qbi-intern-s...
10 months ago
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We look forward to hosting Dr. Ludovic Deriano of Institut Pasteur
@pasteur.fr
next week at UCSF on August 5! He’ll share how BRCA1/2-deficient cells adapt to DNA damage and how CRISPR screens reveal new targets for cancer therapy. Learn more & save your spot:
qbi.ucsf.edu/seminar-deri...
10 months ago
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QBI-UCSF launches the Paul Farmer African Initiative for Research (PFAIR) to strengthen research capacity across Africa by building a foundation for sustainable research through mentorship, funding, and international exchange for African scientists. Learn more:
www.ucsf.edu/news/2025/07...
10 months ago
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We look forward to having Dr. Andy Kilianski of ARPA-H at QBI for a seminar! Join us to learn how ARPA-H is investing in bold, high-impact research to transform the future of health in the U.S. Learn more & register:
qbi.ucsf.edu/seminar-kili...
11 months ago
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We’ve enjoyed having Hoai Nguyen as a visiting scholar this summer! Join us July 14 as she wraps up her time at QBI and
@gladstoneinst.bsky.social
with a seminar on her team’s CRISPR-based dengue virus diagnostic assay.
qbi.ucsf.edu/seminar-hoai...
#GlobalHealth
#CRISPR
#Dengue
11 months ago
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Dari Kimanius (
@czbiohub.bsky.social
) is joining us at UCSF
@ucsanfrancisco.bsky.social
for next week’s AI in Biology symposium! He’ll share how ML is advancing in situ Cryo-ET and how foundation models are enabling high-throughput discovery. See full speaker lineup:
qbi.ucsf.edu/ai-symposium...
12 months ago
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Longtime collaborators Steven Altschuler & Lani Wu will share how AI helps map cell phenotypes for early drug discovery, while stressing the need for biological validation. Hear them at “AI in Biology” @UCSF, June 17–18.
qbi.ucsf.edu/ai-symposium...
#QBI
#AIinBiology
#UCSF
#BiotechInnovation
12 months ago
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Next week at UCSF: Brian Cheung of MIT will share how large language models can grasp the real world, even without seeing or hearing a thing! Catch him at the QBI/Rezo “AI in Biology” symposium June 17–18. Few tickets left:
qbi.ucsf.edu/ai-symposium...
#QBI
#AIinBiology
#UCSF
#BiotechInnovation
12 months ago
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Meet Cecilia Clementi, Physics Prof at
@freieuniversitaet.bsky.social
+ speaker at the QBI/Rezo “AI in Biology” symposium next week! Join us June 17–18 at UCSF
@ucsanfrancisco.bsky.social
:
qbi.ucsf.edu/ai-symposium...
#QBI
#Rezo
#AIinBiology
#UCSF
#BiotechInnovation
12 months ago
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Meet Anil Palepu, Research Scientist at Google and speaker at our QBI/Rezo Therapeutics “AI in Biology” symposium on June 17-18! Register to join:
qbi.ucsf.edu/ai-symposium...
#SpeakerSpotlight
#QBI
#AIinBiology
#RezoTherapeutics
#ScienceSymposium
#BiotechInnovation
#ai
12 months ago
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Meet Angela Oliveira Pisco, Head of Computational Biology at inistro
@insitro.bsky.social
and speaker at our QBI/Rezo “AI in Biology” symposium on June 17-18! Register to join:
qbi.ucsf.edu/ai-symposium...
#SpeakerSpotlight
#QBI
#AIinBiology
#RezoTherapeutics
#ScienceSymposium
#BiotechInnovation
about 1 year ago
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Join us June 17–18 at UCSF for “Separating the Signal from the Noise: AI in Biology” — a 2-day symposium with speakers from Google, Genentech, Insitro, MIT, Freie Universität Berlin, CZI, University of Toronto, Alberta Machine Intelligence Institute, QBI UCSF, and Rezo!
qbi.ucsf.edu/ai-symposium...
about 1 year ago
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From AI-driven discoveries to building collaborative ecosystems, QBI Director Nevan Krogan shares his vision for the future of science-and why Berlin is an exceptional partner in that mission. Read the full Q&A via
@einsteinberlin.bsky.social
:
www.einsteinfoundation.de/en/questionn...
about 1 year ago
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QBI & Thermo Fisher are hosting a Lunch & Learn on May 9 at UCSF! Learn how to set up robust quantitative proteomics experiments using cutting-edge mass spectrometry with insights from Kevin Yang & Rafael Melani. Lunch included! Learn more & register:
qbi.ucsf.edu/qbi-thermo-f...
about 1 year ago
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