Open Postdoc Position - Giant E3 ligases: mysterious mechanisms & non‑protein substrates. Interested? Join us to uncover how these molecular giants tag lipids, RNAs, sugars beyond proteins, on organelles and pathogens, to defend the cell. Details & Application here www.imp.ac.at/career/open-...

📣 Registration is open for the 20th Microsymposium on RNA Biology! Join in at the Vienna BioCenter for three days of cutting-edge science, discussion & networking. 📅 17-19 June 2026 🧬 Poster abstract deadline: 19 May Info & registration: www.oeaw.ac.at/imba/seminar...

Excited to share a new preprint from the lab led by @lukekoblan.bsky.social and William Colgan in which we describe our efforts to define a quantitative cell fate map of mouse embryogenesis! www.biorxiv.org/content/10.6...

Check out the phenomenal PhD work by Katie Copley, a current postdoc in our lab @yaleneuro.bsky.social @yalerna.bsky.social. www.science.org/doi/10.1126/...

How do mitochondrial ribosomes keep pace with membrane insertion? Now out in NSMB: We show that mitoribosomes slow down at defined positions linked to membrane insertion and protein topology: rdcu.be/fhqIT #Mitochondria #Ribosome #CryoEM

Now online at @natplants.nature.com ‼️ Led by Jierui Zhao, a former PhD student @gmivienna.bsky.social & together w/ @moritznowack.bsky.social lab, we uncover how #autophagy shapes salt stress tolerance and lifespan. www.nature.com/articles/s41... www.nature.com/articles/s41... A short 🧵👇

My favourite meeting of the year has arrived again! 👇🤩

🚨 Paper out now in #ScienceAdvances @science.org 🌱🦠 Pathogens don’t just target protein degradation—they also hijack host translation. "Bacteria use P-body condensates to attenuate host translation during infection" ⚖️♻️ led by @manuelgonzalezfuen.bsky.social www.science.org/doi/10.1126/...

Final call for postdoctoral positions in my lab in wonderful Århus. You may apply using this link: mbg.au.dk/en/news-and-...

A new paper in which we could contribute structural insights to the great biochemical work from our collaborators from UNC Chapel Hill. Sascha Amann from our lab was yet again able to solve several very challenging structures. This time of a SCF with Protac and target www.nature.com/articles/s41...

New from our lab @crick.ac.uk. Nascent proteins emerge from the human ribosome into a cytosol packed with hundreds of different molecular chaperones. Which chaperones recognise specific nascent chains, and what dictates their binding preferences? www.biorxiv.org/content/10.6...

This is .wild. !

Now out in its final form! www.science.org/doi/10.1126/...

Out now in @science.org Repurposing of a DNA segregation machinery into a cytoskeletal system controlling cell shape | Science www.science.org/doi/10.1126/...

Our lab is looking for a lab technician! If you share our passion for fundamental research and happy to contribute, join us!

🔬 Passionate about RNA biology? Join the lab of @sebastianfalk.bsky.social for your Master's project to explore the function of proteins and protein complexes using cutting-edge biochemical, structural, and cell biology approaches ➡️ tinyurl.com/3k7upan4

We offer a PostDoc position for a fully funded project on lipid-encoded #lipidtime protein quality-control checkpoints at the Golgi: great collaborators, excellent working & living conditions & benchspace with a view ;) Please share and repost!

Out now in @science.org Harnessing viral strategies to reverse cognitive dysfunction through the integrated stress response | Science www.science.org/doi/10.1126/...

Exciting job offer: PhD Program Manager. Lead recruitment, support PhD candidates, and shape doctoral training at a top international life sciences campus. https://ow.ly/3YkN50YAuGM Institute of Molecular Biotechnology, Max Perutz Labs Vienna, IMP, Gregor Mendel Institute of Molecular Plant Biology

New opportunity with the Vienna BioCenter Scientific Training Team! 🙌 As PhD Program Manager, you’ll play a key role in empowering and shaping the careers of the next generation of world-class researchers ➡️ tinyurl.com/yrk23na2

Congrats to Ni, Dagdas lab and everyone involved! Happy to contribute to this exciting work!

Excited host @hohmannulrich.bsky.social from @imbmainz.bsky.social, along with @manuelkaulich.bsky.social Date: 07.04.2026 Time: 15:00 Venue: Haus 22 Seminar Room 1. (S22-1) Title: ‘Mechanistic insights into nuclear mRNA export and degradation’ @goetheuni.bsky.social @cpi-exstra.bsky.social

Looking for an exciting and ambitious Master’s project? 👀 Join the @huis.bsky.social lab, where two Master’s positions are currently available to explore how genome stability and chromosome segregation are controlled in human cells ➡️ tinyurl.com/ybddpx7c

What are the roles of UFMylation during ribosome-associated quality control? @gekaragoz.bsky.social @plantophagy.bsky.social and colleagues find it to cooperate with RQC factors in promoting clearance of arrested nascent polypeptides at the ER link.springer.com/article/10.1...

Congrats Milica @alessandrick.bsky.social & everyone @gekaragoz.bsky.social lab. Glad we could contribute to this awesome story on #UFMylation & #RQC crosstalk @embojournal.org link.springer.com/article/10.1...

Our work on the role of Ufmylation on ribosome quality control on the ER is out! Great work of two terrific first authors Milica and @alessandrick.bsky.social together with our wonderful collaborators, the one and only Dagdas lab @plantophagy.bsky.social!

Excited to share our work on the structure and function of cytoplasmic lattices within mouse embryos. A collaborative effort with @niakanlab.bsky.social and work led by @kashishsingh.bsky.social and @inaharasimov.bsky.social . It is now out on BioRxiv: www.biorxiv.org/content/10.6...

It’s incredibly hard to study lipids in biological membranes on the nanoscale. You need near-perfect information on both membrane ultrastructure and lipid density. Lipid-CLEM, now out in @natcellbio.nature.com brought to you by @mathilda95.bsky.social changes that: www.nature.com/articles/s41...

The BioOptics facility will expand their team with a Junior Imaging Scientist with a background in Biological Sciences, who is enthusiastic about applying cutting-edge light microscopy for imaging-based research 🔬 Join a collaborative service team at the Perutz today! ➡️ tinyurl.com/5n7m2dyw

The E3 ubiquitin ligase mechanism specifying target-directed microRNA degradation (TDMD) is now published! 🎉🍾 We, @bartellab.bsky.social and Schulman lab, describe how 2-RNA factors control protein degradation by recruiting an E3 ligase. @mpibiochem.bsky.social www.nature.com/articles/s41...

🚨 Out now! 🧫 In a new study in @embojournal.org, PhD student @moberhuemer.bsky.social (Leeb lab) presents a simpler, feeder-free way to grow human naïve pluripotent stem cells - making the system more scalable and accessible ➡️ tinyurl.com/29wrcdru @univie.ac.at @meduniwien.ac.at

We are grateful to FWF for their support! It is a privilege to be part of this amazing team and work on this exciting truly collaborative project! Stay tuned!

Ubiquitin & Friends Fiesta in Vienna, 29-30 April 2026. Great speakers, small size, a friendly community, perfect for early-career researchers to connect with fellow ubiquitin enthusiasts. Sign up at www.protein-degradation.org/symposium/ and submit abstracts for talks and awards. #ubfriends26

Registration is now open for the EMBO Workshop "#Ubiquitin and ubiquitin-like proteins in health and disease" in #Monopoli, Italy, 28 Sep–2 Oct 2026. Registration deadline: 31 May Abstract submission deadline: 15 Jun https://meetings.embo.org/event/26-ubiquitin#Ubiquitin#Monopoli#EMBOubiquitin #EMBOevents 🧪

Fantastic news! 🙌 The Perutz is excited to welcome Danny Nedialkova as a new group leader starting this April! 🎉 She will strengthen the institute's research on the fundamental mechanisms that shape cellular physiology and disease ➡️ www.maxperutzlabs.ac.at/research/res...

Our most recent work on the “function and evolution” of #nuclear-speckles is now online at Cell @cp-cell.bsky.social doi.org/10.1016/j.ce... Read the thread👇 for the highlights of our findings.

Sooo happy to share our new paper in @nature.com “CLCC1 promotes hepatic neutral lipid flux and nuclear pore complex assembly.” A terrific collaboration with @arrudalab.bsky.social, led by co–first authors Alyssa Mathiowetz and Emily Maymand. www.nature.com/articles/s41...

Our paper on The Lipid Interactome is now published, and the database is open: lipidinteractome.org @ohsummi.bsky.social @ohsunews.bsky.social @nadlerlab.bsky.social @jeremybaskin.bsky.social Please RT to spread the word. doi.org/10.1093/bioi...

Very much looking forward to it!

Huge congrats to Alibek and everyone involved! It is a great work!

SAVE THE DATE: Ubiquitin & Friends Symposium 2026 on April 29-30 or even better, sign up now: lnkd.in/eEQmaCYT It takes place at Van Swieten Hall, 1090 Vienna & is organized by the SFB Targeted Protein Degradation (incl. numerous research groups at Vienna BioCenter) @sfb-tpd-vienna.bsky.social

🍰Read also the News & Views article written by Yu-Xi Xiao & Alan M. Moses: 👉https://rdcu.be/e4W1D bit.ly/4kO0Lua

The ribosome synchronizes folding and assembly to promote oligomeric protein biogenesis

Mammalian cells form hibernating disomes akin to those in bacterial cells - but connected via ribosomal RNA www.science.org/doi/10.1126/... co-first with: @andschwarz.bsky.social with: @lea-dietrich.bsky.social, @sgiando.bsky.social, @erin-schuman.bsky.social and many more 🧵 0/6 #MolBio 🧪

👀 Curious about how RNA is shaped inside cells? Apply for a Master’s thesis in the Martinez Lab and investigate the mechanisms and functions of tRNA processing in health and disease ➡️ tinyurl.com/4hxm6x8p

Our paper is out in @natcomms.nature.com! APOBEC3s drive mutagenesis in cancer. We uncover a novel pathway keeping them in check. The key is APOBEC3 binding of cellular RNAs, which simultaneously controls their nuclear localization and shields them from degradation. Read it here: rdcu.be/e4qaa

Nature research paper: Sleep-dependent clearance of brain lipids by peripheral blood cells go.nature.com/4rRrkAV

@hanhtkvu.bsky.social @embl.org & we are looking for a #postdoc to study #regeneration x #autophagy across kingdoms of life. Pls spread the word & get in touch if you are interested www.health-life-sciences.de/opportunitie...

New preprint from the lab together with @labvanni.bsky.social. We looked what happens to ER generated free very long chain fatty acids.. VLCFAs are partionig into lipid droplets and are extracted from the hydrophobic core by Fat1. www.biorxiv.org/content/bior...

Why do pathological protein aggregates persist in cells and how can we overcome this? In our new preprint, we show that Tau aggregates fail to initiate selective autophagy and that their autophagic degradation can be restored. #Autophagy #Tau #Proteostasis Out now 👇 www.biorxiv.org/content/10.6...