📢 Open Call! The Max Perutz Labs invite applications for a Full Professorship in Integrative Structure Biology with a focus on in situ structural biology using cryo-electron tomography (cryo-ET) and related methods. More details ➡️ tinyurl.com/brswbymu

When transposons jump, genomes diverge - even in cultured cells. I am happy to share our new preprint: a chromosome-scale genome assembly for Drosophila OSC cells, one of the key model systems in the piRNA field, especially for nuclear piRNA biology. 🧬🧵 (1/12)

Professorship in plant genetics. The Botanical Institute at Kiel University is advertising a W2 professorship. Great opportunity to do plant research in the north of Germany. See: www.berufungen.uni-kiel.de/de/dateien/o...

PIWI clade Argonautes are essential for transposon silencing. Without them, animals are sterile due to massive transposon activity. But how does piRNA-guided target interaction translate into silencing? PhD student Júlia Portell Montserrat has an intriguing answer www.cell.com/molecular-ce...

I am excited to announce that I will be moving to IMB Mainz next year! The Winter call for the IPP PhD program is now open; if you are interested in maternal #mRNA regulation and #translation in early vertebrate development, please apply! Deadline: 16 October. More info: www.imb.de/students-pos...

Join us for the Austrian Cryo-EM Symposium Nov 11–12 at @istaresearch.bsky.social! Top speakers, cutting-edge cryo-EM, and a chance to explore Vienna & the ISTA campus. Register now 👉 cryoem-symposium.pages.ist.ac.at #cryoEM #teamtomo

🎉 Congrats to @kgaurav.bsky.social, Lukas Stelzl & @reneketting.bsky.social (SFB1551) on their new Biophysical Journal paper! #MUT16 #PhaseSeparation #MutatorFoci #SmallRNA #GeneRegulation #Celegans #ProteinAssembly #RNAResearch #MultiscaleSimulations Great teamwork👏👏👏 www.cell.com/biophysj/ful....

Happy to share the latest work on a bacterial protein that inhibits human mRNA decay machinery, in collaboration with @smlea.bsky.social #RNAsky www.nature.com/articles/s41... Intracellular pathogen effector reprograms host gene expression by inhibiting mRNA decay | Nature Communications

This guy…..

Exciting and rare opportunity to join the @maxperutzlabs.bsky.social and the @viennabiocenter.bsky.social as a Full Professor! www.nature.com/naturecareer...

Congratulations Marco and team. Great to see it published 🎉

🚀 Group leaders Peter Schlögelhofer, Robert Konrat, and @sebastianfalk.bsky.social have secured @fwf-at.bsky.social projects, bringing in nearly €1.5 million. Their projects span mRNA processing, novel NMR methods, and chromosome architecture ➡️ tinyurl.com/3a6j3pw8 @univie.ac.at @meduniwien.ac.at

If only funders saw the bigger picture… The obsession with medical research has come at a cost: plant biology has been sidelined, with countless discoveries stalled. Just look at Barbara McClintock, who discovered mobile genetic elements—only to be dismissed at the time of her groundbreaking work.

Reisen mit Deutschen Bahn; immer wieder ein Erlebnis, leider selten ein schoenes. ICE228 von Wien nach Wue; 5 h Fahrt und nur drei funktionierende Toiletten im ganzen Zug. Der Zug ist voll.. mehr als 20 minuten Anstehen fuer menschliche Beduerfnisse. @deutsche-bahn.bsky.social @bahn.bsky.social

Earnshaw, Goloborodko, Dekker & Mirny labs are excited to present our latest work, "Rules of engagement for condensins and cohesins guide mitotic chromosome formation" - now accepted!! www.science.org/doi/10.1126/... A short clip describing the key results: www.youtube.com/watch?v=pmvO...

Why NIH/NIGMS funding of basic research matters with our latest work now out in @cp-cellreports.bsky.social sky.social. We solved a >30-year-old mystery of what transcription factor drives the Flamenco piRNA cluster required for female Drosophila fertility. /1 www.cell.com/cell-reports...

www.nature.com/naturecareer... UBC LSI Job!!

🚨 Out now! The Leonard lab reveals in @pnas.org that phosphatases PHLPP1/2, once thought to dephosphorylate Akt and suppress tumors, are actually catalytically inactive. Instead, they have a non-catalytic role, reshaping our understanding of Akt regulation ➡️ tinyurl.com/hf28b3mu @univie.ac.at

This is Yale Professor Timothy Snyder, who studies authoritarians and tyranny, with a warning. He and another Yale professor, Jason Stanley, who studies similar topics at Yale, are moving to Canadian universities, a result of the political and academic climate here.

Our paper on prediction of phase-separation propensities of disordered proteins from sequence is now published: www.pnas.org/doi/10.1073/... The paper has been substantially updated compared to the preprint including new experimental data and using the neural network to finetune CALVADOS. 1/n

📯📯📯 10 days left to apply for the International Master MemBioMed "From Membrane Biology to Neuroscience & Experimental Medicine". Scholarships available for selected students to acquire intensive training in analysing the complex behavior of biomembranes and exploiting their therapeutic potential 👇👇

Super excited to share our latest work on deciphering the #Ubiquitin Code “𝗨𝗯𝗶𝗥𝗘𝗔𝗗 𝗱𝗲𝗰𝗶𝗽𝗵𝗲𝗿𝘀 𝗽𝗿𝗼𝘁𝗲𝗮𝘀𝗼𝗺𝗮𝗹 𝗱𝗲𝗴𝗿𝗮𝗱𝗮𝘁𝗶𝗼𝗻 𝗰𝗼𝗱𝗲 𝗼𝗳 𝗵𝗼𝗺𝗼𝘁𝘆𝗽𝗶𝗰 𝗮𝗻𝗱 𝗯𝗿𝗮𝗻𝗰𝗵𝗲𝗱 𝗞48 𝗮𝗻𝗱 𝗞63 𝘂𝗯𝗶𝗾𝘂𝗶𝘁𝗶𝗻 𝗰𝗵𝗮𝗶𝗻𝘀” @cp-molcell.bsky.social 1/8 www.cell.com/molecular-ce...

Great talks & discussions at the 76th Mosbacher Kolloquium last week - in particular fantastic Lynen Lecture by Tanja Kortemme @kortemmelab.bsky.social and Eduard-Buchner award lecture by Dorothee Kern! And great to see so many old and new friends. @gbmev.bsky.social

One week left to register and submit abstracts for being considered for talks at our upcoming #EMBO Meeting "RNA Meets Protein Degradation" in Vienna! Check out the program with a fantastic line-up of speakers, including keynotes by Rachel Green and Manu Hedge. meetings.embo.org/event/25-rna...

Microtubules in Asgard archaea @cellpress.bsky.social @pilhoferlab.bsky.social www.cell.com/cell/fulltex...

🎉 Today, we look back on a milestone moment in Perutz history! On this day in 2005, the rectors of the University of Vienna and the Medical University of Vienna, Georg Winckler and Wolfgang Schütz, signed the notarial deed, officially establishing the Max Perutz Labs. 🧬🎊 #MaxPerutzLabs20Years

This is what we’ve come to, and so quickly.

Mit einem offenen Brief fordern Wissenschaftler aus ganz Deutschland die neue Bundesregierung auf, Klimapolitik ernst zu nehmen – und sammelten innerhalb weniger Tage mehr als 12 000 Unterschriften von Kollegen. www.saarbruecker-zeitung.de/sz-spezial/k...

Dass eine der letzten Dinge, die Sahra Wagenknecht als Abgeordnete des Deutschen Bundestags tut, eine Empfehlung an ihre alte Partei, mit der AfD zusammen zu arbeiten, ist, bringt diese politische Laufbahn auch irgendwie sehr auf den Punkt.

A fantastic meeting of early career researchers in Vienna this week. It was great to see old friends and to meet new people. Thank you so much for the opportunity to present my work at SY-Stem 2025! @impvienna.bsky.social @imbavienna.bsky.social @maxperutzlabs.bsky.social

Interesting! #RNADecay #RNAExosome #RNA #ncRNA Defining the roles of the #Integrator, #NEXT, and #nuclear #exosome complexes in #Drosophila #oogenesis Yongjin Lee, Adriano Biasini, Cindy Tipping, Seong Hyeon Hong, Phillip Zamore www.biorxiv.org/content/10.1...

ACTION ITEM I was chatting with a young scientist who expressed concern re the multiplicity of ongoing issues Over the course of our conversation, we arrived at the idea of a DASHBOARD where issues could be tracked If anyone is interested in helping with this (ideally with expertise) please DM me

Join us in Vienna for exciting #RNA biology! The deadline to submit an abstract for a talk is Friday, February 28th. #microsymposium2025 #smallrna #events #vienna

Reminder - still one month to apply to be a tenure track group leader at MRC LMB. Please do reach out for any information.

#theconferencetoendallconferences ... it's coming! Registration should (will!) open on March 1st, we are working on it, the web is being born thanks to ITs from @imgprague.bsky.social working day & night ... I just tested the registration site ... get ready.

🤔 Ever wondered how top-quality monoclonal antibodies are made? In the fourth part of our facilities series, we take you inside the Monoclonal Antibody facility, where experts produce tailor-made antibodies ➡️ tinyurl.com/mt29aac5 @univie.ac.at

Happy and grateful—what a journey it has been! I’m excited about the chance to continue our work on RNA metabolism at @maxperutzlabs.bsky.social and @viennabiocenter.bsky.social, one of Europe's major hubs for RNA biology. Many thanks to my team, colleagues, and @univie.ac.at for their support!

Congrats to Perutz group leaders Elif Karagöz and @shotarootsuka.bsky.social on becoming tenured professors 🎉 Since 2019, the Karagöz lab has been uncovering how cells maintain protein homeostasis, while the Otsuka lab explores how the ER and nucleus communicate ➡️ tinyurl.com/2phzhprj

Long before the Max Perutz Labs were officially founded in 2005, a group of ambitious young molecular biologists - some of them shown below - dreamed of creating a research institute that would unite the strengths of scientists in a cross-university initiative 🙌 #MaxPerutzLabs20Years @univie.ac.at

2025 marks an incredible milestone: it is the 20th anniversary of the Max Perutz Labs! 🎉 This is a chance not only to celebrate how far we’ve come but also to be inspired by the bold vision that started it all and to carry that energy forward into the next 20 years. Stay tuned! #MaxPerutzLabs20Years

We are looking for new group leaders. If RNA is your thing, and/or computational biology and you want to start your own group, check out these links. Feel free to contact me about these! And, please help me spread this. Thanks! www.imb.de/jobs/jobdeta... www.imb.de/jobs/jobdeta...

Paper alert! 📢 The inner nuclear membrane is a hub for the lipid metabolism. In a new @natureportfolio.bsky.social Comms study, the Köhler lab uncovers Seipin as a key regulator in maintaining lipid balance and nuclear envelope integrity 🌟 Read more ➡️ tinyurl.com/ycy7pjkh @univie.ac.at

Interesting findings by the Zarnack and König labs: www.cell.com/molecular-ce... #RNAbiology

We discovered the first alternative genetic code in Archaea! www.biorxiv.org/content/10.1...

Join us at the Ubiquitin & Friends meeting in beautiful Vienna, 2-3 May 2024. Great speakers, small size, a friendly community, perfect for early-career researchers to connect with fellow ubiquitin enthusiasts. Sign up at protein-degradation.org/symposium/. Submit abstracts for talks and awards.

Tiere kontrollieren die Ausbreitung von Transposons im Genom sehr streng. Wie @sebastianfalk.bsky.social & Co. von den @maxperutzlabs.bsky.social verkünden, helfen dabei kurze RNAs, an deren Herstellung ein neuartiger Enzym-Typ mitwirkt. — Mehr von Larissa Tetsch: www.laborjournal.de/editorials/2...