birtehoecker.bsky.social
@birtehoecker.bsky.social
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Biochemist at Bayreuth University, Germany, interested in protein evolution & design
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birtehoecker.bsky.social
Kresten Lindorff-Larsen
12 days ago
Come join the new Novo Nordisk Foundation Center for Protein Design as a group leader Cool science in a great scientific environment in wonderful and very family friendly Copenhagen There are two positions that can either be at TT assistant or associate prof level
employment.ku.dk/tenure-track...
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Tenure-track Assistant Professor or Associate Professor of De novo Protein Design
The Novo Nordisk Foundation Center for Protein Design at the University of Copenhagen seeks to appoint two new group leaders in de novo protein design from 1 February 2027 or as soon as possible thereafter. These positions will be at the Assistant or Associate Professor level and associated with the Department of Biology (Faculty of Science) or the Department of Drug Design and Pharmacology (Faculty of Health and Medical Sciences).
https://employment.ku.dk/tenure-track/?show=163355
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birtehoecker.bsky.social
Roberto Chica Lab
18 days ago
Excited to share our latest with
@birtehoecker.bsky.social
: CANVAS, a de novo enzyme design strategy that builds active sites by adding tailored lids to minimal TIM barrels. Several designs reached kcat values of 13–26 s⁻¹, on par with the median natural enzyme.
www.nature.com/articles/s41...
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Customizing the structure of minimal TIM barrels to craft efficient de novo enzymes - Nature Chemical Biology
The TIM barrel is nature’s most versatile enzyme fold, yet de novo variants lack functional active sites. Minimal de novo TIM barrels have now been converted into enzymes by designing structural lids ...
https://www.nature.com/articles/s41589-026-02250-w
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Today out in Nature Chemical Biology
@springernature.com
. Thanks for great collaboration
@chicalab.bsky.social
add a skeleton here at some point
20 days ago
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birtehoecker.bsky.social
Khmelinskaia Lab
8 months ago
🚨 Registration open! Join us next April on the Belgian coast 🇧🇪 for the FEBS Advanced Course “Generative AI for Protein Engineering” 🧬 A unique, hands-on week dedicated to thinking and designing like a protein engineer. 👉 Info & apply: …proteinengineering2026.febsevents.org
#ProteinDesign
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birtehoecker.bsky.social
Microplastics Research Center
8 months ago
📣New CRC 1357 Publication: The Key to Enzymatic Degradation of Polybutylene Terephthalate (PBT): Influence of Semicrystalline Properties on Degradation
doi.org/10.1002/cssc...
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The Key to Enzymatic Degradation of Polybutylene Terephthalate (PBT): Influence of Semicrystalline Properties on Degradation
This study demonstrates that enzymatic degradation of polybutylene terephthalate (PBT) can be achieved by tuning PBT's semicrystalline properties and incubation conditions. Polymers with a high conte....
https://doi.org/10.1002/cssc.202501775
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birtehoecker.bsky.social
Microplastics Research Center
9 months ago
📣New CRC 1357 Publication: Congrats to Onur Turak, Protein Design
@birtehoecker.bsky.social
, & co-authors and their new article: A third type of PETase from the marine Halopseudomonas lineage Structure & sequence features of type III PETases reported!
onlinelibrary.wiley.com/doi/10.1002/...
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A third type of PETase from the marine Halopseudomonas lineage
The enzymatic degradation of polyethylene terephthalate (PET) offers a sustainable solution for PET recycling. Over the past two decades, more than 100 PETases have been characterized, primarily exhi...
https://onlinelibrary.wiley.com/doi/10.1002/pro.70305
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reposted by
birtehoecker.bsky.social
Roberto Chica Lab
11 months ago
In collaboration with
@birtehoecker.bsky.social
, we’ve unlocked enzymatic activity in a minimal de novo TIM barrel by designing a custom lid for catalysis! 🧵👇
#ProteinDesign
#EnzymeDesign
Customizing the Structure of a Minimal TIM Barrel to Create a De Novo Enzyme
www.biorxiv.org/content/10.1...
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Customizing the Structure of a Minimal TIM Barrel to Craft a De Novo Enzyme
The TIM barrel is the most prevalent fold in natural enzymes, supporting efficient catalysis of diverse chemical reactions. While de novo TIM barrels have been successfully designed, their minimalisti...
https://www.biorxiv.org/content/10.1101/2025.01.28.635154v2
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reposted by
birtehoecker.bsky.social
Ajasja💻🧬🔬
about 1 year ago
Early bird registration for 𝐄𝐔 𝐑𝐨𝐬𝐞𝐭𝐭𝐚 𝐂𝐨𝐧 𝟐𝟎𝟐𝟓 is open! 🎉🎉🎉 Come join us for three days of protein design fun! (October 20-22, 2025) Direct registration link:
pretix.eu/SBD/RCon2025/
Website:
europeanrosettacon.org
We are looking forward to seeing you! Please share this far and wide:)
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We proudly present our GBM-Master awardee 2025: Emma Düthorn. Emma did her thesis in the Mustroph lab and finished 1st in the Bayreuth MSc in Biochemistry & Mol.Biology. We also enjoyed a great GBM lecture by Clara Schroeder (Uni Leipzig) and the Bayreuth JuniorGBM summer party!
@gbmev.bsky.social
about 1 year ago
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Two great weeks at the beautiful UNSW campus in Sydney come to an end - lots of fun discussions with the Curmi lab about protein motors and how to design artificial ones!
about 1 year ago
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Great talks & discussions at the 76th Mosbacher Kolloquium last week - in particular fantastic Lynen Lecture by Tanja Kortemme
@kortemmelab.bsky.social
and Eduard-Buchner award lecture by Dorothee Kern! And great to see so many old and new friends.
@gbmev.bsky.social
over 1 year ago
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birtehoecker.bsky.social
GBM (Gesellschaft für Biochemie und Molekularbiologie)
over 1 year ago
Meet our three poster prize winners that were awarded by GBM president Harald Kolmar: Benedict Wolf (Heidelberg), Julian Beck (Bayreuth) and Lisa Schmidt (Berlin). Thank you
@febsopenbio.bsky.social
for supporting us!
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birtehoecker.bsky.social
GBM (Gesellschaft für Biochemie und Molekularbiologie)
over 1 year ago
Congratulations Dorothee! Laudatio given by Janosch Hennig, co-organizer of the meeting.
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reposted by
birtehoecker.bsky.social
GBM (Gesellschaft für Biochemie und Molekularbiologie)
over 1 year ago
Feodor-Lynen-Lecture delivered by Tanja Kortemme (UCSF) at the Mosbacher Kolloquium. Congratulations!
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birtehoecker.bsky.social
GBM (Gesellschaft für Biochemie und Molekularbiologie)
over 1 year ago
Join us for the
#GBMLunch
📅 February 12 🕛 12:00 PM Lukas Milles
@lfmilles.bsky.social
from the Gene Center of LMU & MPI of Biochemistry, Munich will be presenting on: “Reconstructing biological function with de novo protein design” The session will be chaired by
@birtehoecker.bsky.social
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reposted by
birtehoecker.bsky.social
Kresten Lindorff-Larsen
over 1 year ago
📣 Save the dates 📅 We are organizing a Benzon Symposium on "Protein structure prediction and design" with what I think is an amazing set of speakers Meeting will take place in Copenhagen 🇩🇰 on Sept. 1–4, 2025, and abstract submission will open in March (
benzon-foundation.dk/benzon-sympo...
)
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birtehoecker.bsky.social
GBM (Gesellschaft für Biochemie und Molekularbiologie)
over 1 year ago
Registration is open: 76. Mosbacher Kolloquium "AI-driven (r)evolution in structural biology & protein design" from 20.03.2025–22.03.2025
mosbacher-kolloquium.org
Early registration: January 31, 2025 Poster abstracts: January 31, 2025 Please RT!
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