Do you have a colleague who just finished a major accomplishment and you'd like to commemorate their successes? 3D printed protein models with commemorative bases recognize your colleague's accomplishments in molecular biology. Submit a 3D print request at buff.ly/8x5f0BS

AI has revolutionized study of protein structure and design. UC Davis researchers are taking part in two new NSF-backed projects to apply AI-driven protein engineering in industry. www.ucdavis.edu/news/federal...

AI reveals how toughest protein bonds behave #Science #Biology #MolecularBiology #ProteinResearch #Biotechnology #ArtificialIntelligence

Really excited to receive the ERC Starting Grant! It’s gonna allow us to do a lot of cool protein design and structural biology method development in the next few years!

📢📢Hiring 2 Research Assistants & 2 Postdocs at Emory University in Atlanta to study cytoskeletal biophysics/biochemistry. Please RT. RAs: great for recent bachelor's/master's in Physics/Bio/Chem/Biochem. Email CV and interests to [email protected]. More info: www.shekharlab.org

Exciting to see our protein binder design pipeline BindCraft published in its final form in @Nature ! This has been an amazing collaborative effort with Lennart, Christian, @sokrypton.org, Bruno and many other amazing lab members and collaborators. www.nature.com/articles/s41...

The ideological cancellation of $800 million of scientific research grants because they supposedly focused on DEI was just backed by the Supreme Court. This is horrific on so many levels.

RFdiffusion2 is now live! github.com/RosettaCommo... You can now design proteins, and in particular enzymes from just partially defined amino acid side chains, and without defining their sequence position or order!

Early bird registration for 𝐄𝐔 𝐑𝐨𝐬𝐞𝐭𝐭𝐚 𝐂𝐨𝐧 𝟐𝟎𝟐𝟓 closes in two days! Come join us for three days of protein design fun! (October 20-22, 2025) Direct registration link: pretix.eu/SBD/RCon2025/ Website: europeanrosettacon.org

Repost appreciated: Open #PhDposition in structural virology in my group! Join us in Umeå, Sweden to uncover how arboviruses remodel infected cells. In situ #cryoET and #cryoEM combined with #virology, #cellbiology, and #biophysics. Deadline 7 September. More info: www.carlsonlab.se/join/

Due to popular demand (and summer time), early registration for EU Rosetta Con has been extended until Aug 20th! If you missed the deadline -- there is still time to apply: europeanrosettacon.org

Researchers analysed thousands of natural protein sequences and got assistance from AI in order to design a new hydrogel adhesive that can stay sticky underwater or even within a living body.

⏳ Time flies: only 10 days left for early registration to European RosettaCon 2025 (europeanrosettacon.org) from 20-22 Oct! The speaker lineup is shaping up amazingly well. Join us for three days of cutting-edge protein and biomolecular design topics!

🚨 2 × PhD positions @EPFL! 🚨 Help us push the boundaries of fluorescence microscopy - DNA nanotech, custom optics & spatial omics in Lausanne 🇨🇭. Start Jan 2026. Send CV + motivation + 2 refs → [email protected] #PhD #Hiring #microscopy #SuperResolution #SpatialOmics #DNAPAINT #FLASHPAINT

Take a look at our speakers for the #IBBC2026! Registration is open and we are excited to see you all in Brussels next May! instruct-eric.org/ibsbc2026

We are excited to share our preprint describing DirectContacts2! Here we develop a machine learning model to discriminate between direct and indirect protein interactions. We use our model to construct a highly accurate wiring diagram of the human cell. www.biorxiv.org/content/10.1...

Her name was Diana. She was 23 years old and 7 months pregnant. Russia murdered her today in an attack on the maternity hospital in Kamyanske.

Happy to share the latest work from the lab, led by @mudgal17.bsky.social‬, in collaboration with the Weis lab @ethzurich.bsky.social. How do nuclear membranes fuse during NPC assembly? We answer this question in our latest work, where we identify a new mechanism for membrane fusion… (1/13)

Our study where we develop EvoBind2: Design of linear and cyclic peptide binders from protein sequence information is now published! www.nature.com/articles/s42...

🎉🎉 ljubetic-lab.si🎉🎉 New lab website. We have been working on this in the background for a while, but now it's time to let it out :)

Very interesting technique, will certainly try! Also great external validation of BindCraft, 7/36 binders bound, two with 0.8 and 6 nM affinity! Congratulations on the great work!

You designed binders for your favourite protein and wish there was a way to experimentally screen them within 24h w/ only a set of pipettes and a plate reader? Check out our Cell-Free 2-Hybrid approach (CF2H) Full post: tinyurl.com/48cz5nb6 Preprint: www.biorxiv.org/cgi/content/...

1/6 One of the key features of functional proteins is their inherent structural flexibility. In our recent work at #ICML, we introduce flexibility to protein structure design! More in a thread below. Code / Tutorial: github.com/graeter-grou... Poster: W-109, Thu 17 Jul 11 a.m. PDT — 1:30 p.m. PDT

RFdiffusion: Beta Documentation Now Available We’re excited to announce that RFdiffusion now has official, Rosetta Commons-curated documentation! Read more: rosettacommons.org/2025/07/16/r...

We listened to your feedback. Proscuplt is: *Easier to install - now uses use containers 🚀 *Easier to run in SLURM - specify queue & task details directly in the prosculpt YAML file. github.com/ajasja/prosc... Big thanks to Federico Olivieri, Alina Konstantinova, Nej Bizjak, and Žan Žnidar🙏

🎓 A proud lab moment: our very first master’s student defense is complete! Congratulations to David Krisper for achieving a flawless 10/10 — and thanks to his work mentor Eva Rajh for the wetlab guidance!🎉🎉🎉

One month left until early registration closes! Apply now if you would like to be considered for a talk. It will be an amazing conference bringing together leading scientists in the field of protein design. [Protein Emoji]

Today in the journal Science: BioEmu from Microsoft Research AI for Science. This generative deep learning method emulates protein equilibrium ensembles – key for understanding protein function at scale. www.science.org/doi/10.1126/...

Folddisco finds similar (dis)continuous 3D motifs in large protein structure databases. Its efficient index enables fast uncharacterized active site annotation, protein conformational state analysis and PPI interface comparison. 1/9🧶🧬 📄 www.biorxiv.org/content/10.1... 🌐 search.foldseek.com/folddisco

Finally out in Nature Chem Bio: SNAP-tag2 for faster and brighter protein labeling www.nature.com/articles/s41... Thank you Steffi and Veselin.

Learn about #AI tools in #protein #science, including design and engineering, at the EMBO Practical Course "AI for protein design" in Puerto Varas, Chile, 3–9 November 2025. Deadline: 1 August meetings.embo.org/event/25-ai-... #LifeSciences #research #training #ProteinStructure #EMBOevents 🧪

White text on white background instructing LLMs to give positive reviews is apparently now common enough to show up in searches for boilerplate text.

Fuck

This will take the 🇺🇸 a few generations to rebuild from this.

Exclusive: An international scientific competition widely credited with spurring the development of artificial intelligence for biology appears to be on its deathbed. scim.ag/44ukS90

We have written up a tutorial on how to run BindCraft, how to prepare your input PDB, how to select hotspots, and various other tips and tricks to get the most out of binder design! github.com/martinpacesa...

News from the Rosetta community: Prosculpt – an open-source library integrating RFDiffusion, ProteinMPNN, AlphaFold2 & Rosetta into one easy workflow More via @ajasjaljubetic.bsky.social : rosettacommons.org/2025/05/28/a...

We are very excited to announce that early bird registration for European RosettaCon 2025 is now open! More information here: europeanrosettacon.org

Developing lenacapavir, the drug newly approved to protect against HIV for six months in one shot, took basic science, sophisticated chemistry, and perseverance www.science.org/cont...

Tamarind has a web GUI for this app.tamarind.bio/tools/ablang...

Early bird registration for 𝐄𝐔 𝐑𝐨𝐬𝐞𝐭𝐭𝐚 𝐂𝐨𝐧 𝟐𝟎𝟐𝟓 is open! 🎉🎉🎉 Come join us for three days of protein design fun! (October 20-22, 2025) Direct registration link: pretix.eu/SBD/RCon2025/ Website: europeanrosettacon.org We are looking forward to seeing you! Please share this far and wide:)

Great opportunity for a Research Support Officer to join @cellbiol-mrclmb.bsky.social, supporting @deriverylab.bsky.social in their studies of the molecular mechanisms behind receptor sorting in endosomes. More info: www.nature.com/naturecareer... Apply by 10 JUL #ScienceJobs

Chatbots — LLMs — do not know facts and are not designed to be able to accurately answer factual questions. They are designed to find and mimic patterns of words, probabilistically. When they’re “right” it’s because correct things are often written down, so those patterns are frequent. That’s all.

I spoke with Jade Hindmon, host of @kpbssandiego.bsky.social Midday Edition, about the consequences of the current administration’s cuts to science funding. Please share to help spread the word and raise awareness. www.kpbs.org/podcasts/kpb...

Nature goes full open review! I have complicated feelings about how and when this was achieved! And they should be apparent to you after even a moment’s thought about the subtext here! www.nature.com/articles/d41...

🌟 We are hiring! Seeking a postdoc to use molecular dynamics and AI to understand how ion channels are regulated by membrane lipids 🌟 Join us at #scienceanu with amazing collaborators and great working conditions! Email me (karri.anu.edu.au) or apply here (tiny.cc/corry). Please share & repost!

Proteins operate on a short timescale — on the order of a millisecond, or even faster https://go.nature.com/4l7qAEm

Got the car ready

🎉 JupyterLite 0.6 is now available, and brings exciting new features: ✨ Interactive input() support 🔄 New REPL options 🎯 Better kernel status and logs ⚡️ Improved multi-tab experience Read more: blog.jupyter.org/jupyterlite-... Walkthrough video: www.youtube.com/watch?v=jkQ9...