Science update: Baker lab introduces NeoNectins, which help the body respond to surgical implants, healing gels, and other biomaterials. The study was led by postdoctoral scholar Xinru Wang, PhD, and visiting researcher Jordi Guillem-Marti, PhD Quick read: rosettacommons.org/2025/06/26/d...

We'd like to thank our generous sponsors for making SRC 2025 a successful event. Your support fueled innovation, collaboration, and community. Our sponsors this year: @vilyatx.bsky.social, Lila Biologics, Merck, NOVOPROTEIN, and @levitate.bio. Explore these companies and their great work.

Members of IPD: Gaurav Bhardwaj, Frank DiMaio, and 2024 Nobel laureate David Baker have unveiled a deep-learning framework capable of de novo design of macrocyclic peptides that bind proteins with nanomolar affinity and remarkable precision. Read more: rosettacommons.org/2025/06/26/i...

Registration for the Biomolecular Modeling and Design with Rosetta and ML Tools Workshop (November 17–19, 2025) is now open. The goal of the workshop is to educate and train academic and industry users on the Rosetta software suite. Explore more: meilerlab.org/tutorials/

We're excited to introduce our #RaMP 2025-2026 cohort. Watch this space for more updates.

RFdiffusion: Beta Documentation Now Available We’re excited to announce that RFdiffusion now has official, Rosetta Commons-curated documentation! Read more: rosettacommons.org/2025/07/16/r...

We listened to your feedback. Proscuplt is: *Easier to install - now uses use containers 🚀 *Easier to run in SLURM - specify queue & task details directly in the prosculpt YAML file. github.com/ajasja/prosc... Big thanks to Federico Olivieri, Alina Konstantinova, Nej Bizjak, and Žan Žnidar🙏

We’re making a few intentional changes to our US-based Rosetta conferences next year to better support our growing community. We want to hear what you think. Learn more about the changes: rosettacommons.org/2025/06/26/l... Share your thoughts: docs.google.com/forms/d/e/1F...

RC Biosecurity Fellowship is accepting proposals: 12-month program offers a chance to shape how protein design tools are developed & governed. Fellows lead initiatives, engage with our labs & policy experts, & help bridge science and policy around biosecurity. rosettacommons.org/2025/06/26/r...

News from the Rosetta community: Prosculpt – an open-source library integrating RFDiffusion, ProteinMPNN, AlphaFold2 & Rosetta into one easy workflow More via @ajasjaljubetic.bsky.social : rosettacommons.org/2025/05/28/a...

We are very excited to announce that early bird registration for European RosettaCon 2025 is now open! More information here: europeanrosettacon.org

Early bird registration for 𝐄𝐔 𝐑𝐨𝐬𝐞𝐭𝐭𝐚 𝐂𝐨𝐧 𝟐𝟎𝟐𝟓 is open! 🎉🎉🎉 Come join us for three days of protein design fun! (October 20-22, 2025) Direct registration link: pretix.eu/SBD/RCon2025/ Website: europeanrosettacon.org We are looking forward to seeing you! Please share this far and wide:)

Summer RosettaCon 2025 registration will close this Sunday, June 1, at 11:59 PM EDT. Register now on RosettaCon.org. This year, we have a new panel format for our talks, covering protein design with Rosetta and deep learning, as well as other modeling topics you're interested in, and much more!

Our Rosetta Commons Research Experience for Undergraduates (REU) students have completed the first leg of the program with the @jeffreyjgray.bsky.social lab at the Johns Hopkins University and are now heading to their host labs for the summer. Stay tuned for more!

How to train your model. This immersive, hands-on, advanced-level event is designed for researchers who are ready to move beyond “out-of-the-box” machine learning models for protein design. Join us for this Summer RosettaCon 2025 workshop/hackathon, more here: rosettacommons.org/2025/05/30/h...

Consider joining us for the SRC2025's 1-day Protein Design: One-day novice-level course surveying popular tools and workflows for modern protein design with brief exploration of common applications including antibody design and binder design. rosettacommons.org/2025/06/03/1-day-protein-design/

One-day novice-level course surveying popular tools and workflow for modern protein design with brief exploration of common applications including antibody design and binder design: 1-day Protein Design Workshop. Register here: tinyurl.com/SRC25-worksh...

Register for SRC25 Workshop (tinyurl.com/SRC25-worksh...) : How to train your model - This immersive, hands-on advanced-level event is designed for researchers who are ready to move beyond “out-of-the-box” machine learning models for protein design.

Come hang out with us — Registration for Summer RosettaCon 2025 is open! It will be held at Suncadia Resort in Washington from August 4 - 7, 2025. Register here: rosettacon.org

Our team is growing! We are delighted to share the addition of two new members to the Open Rosetta team at OMSF. Please join us in welcoming Rachel Clune, Ph.D. as our new Documentation Writer and Hope Woods as our new Technical Product Lead. Read more: rosettacommons.org/2025/05/15/w...

We are pleased to announce that Summer RosettaCon 2025 will take place at Suncadia Resort in Washington from August 4 to 7, 2025. Registration is now open: rosettacon.org/registration/ Find details here: rosettacommons.org/2025/04/20/s... We look forward to seeing you there!

We received 613 applications—and now we’re proud to welcome 23 students to the 2025 Rosetta Commons REU! Read more about what they have to tell you about themselves and highlight their goals and interests: 🔗 rosettacommons.org/2025/04/11/i...

Announcing the new RC AlphaRed container designer to run AlphaRed. AlphaFold-initiated replica exchange protein docking is a pipeline to predict protein complex structures from sequences. Read more: github.com/Graylab/Alph...

Save the date: Summer RosettaCon 2025 will happen from Aug 4-7, 2025 in Cle Elum! Registration opening soon New for 2025: SRC will feature thematic scientific panels (not individual submissions). If you're interested in organizing or joining a panel, please sign up here: tinyurl.com/SRC25-Panels

Winter RosettaCon 2025 brought together a community of 335 participants. The scientific organizers Anum Glasgow and Sergey Ovchinnikov created a program featuring 40 talks, showcasing research from academia, industry, and external participants. Read more rosettacommons.org/2025/03/20/w...

BindCraft is a new AI de novo binder design tool from the Correia lab with 10-100% success rates. It's available today as an easy to use API using our API framework so you can deploy it in your own pipeline today. Contact us at levitate.bio/contact to get started www.biorxiv.org/content/10.1...

The RaMP program is still accepting applications till March 1, 2025. This one-year fellowship program is intended for students to gain research experience to succeed in PhD programs. Learn more here: rosettacommons.org/education/ra...

Calling all Rosetta Commons community, This is a reminder that registration for Winter RosettaCon 2025 closes TOMORROW at 11:59 PM EST. You can register and find more information at www.winterrosettacon.org

Register now for a 10% sale on Workshop pricing. Join us in Boston Feb 24-26 for a Protein-Protein Interaction Design Workshop. This intensive, hands-on, 2.5-day boot camp is designed for industry professionals to master protein-protein interaction (PPI) design. winterrosettacon.org/workshop-2025/

Join us in Cambridge, Boston (Feb 24-26, 2025) for Designing Protein-Protein Interactions, a hands-on Rosetta Workshop Event. Led by Amrita Nallathambi (UNC-Chapel Hill, Kuhlman Group). Learn more: lnkd.in/g_2ErSGS

The Rosetta Commons Research Experience for Undergraduates (REU) program accepts applications until February 1, 2025. Apply now and participate in research using the Rosetta Commons software. Learn more here: rosettacommons.org/education/reu/ #REU #RosettaCommons #Undergraduateprogram

We’re thrilled to host the Rosetta Commons Intro to PyRosetta & Machine Learning for Protein Design Bootcamp at the UC Davis Campus. With Deniz Akpinaroglu, our expert instructor. Participants are diving into the fundamentals of top-performing protein design software. #ProteinDesign #RosettaCommons

Winter RosettaCon: Early registration deadline extended to Jan 8 Good news! The early registration deadline for Winter RosettaCon has been extended to January 8. Additionally, the travel award deadline has been extended to January 6. Learn more: winterrosettacon.org

Registration for the RosettaWorkshop is now open, to be held March 3-5, 2025, in person at Vanderbilt University in Nashville, TN. For more information and to register for the workshop, please visit meilerlab.org/rosetta-work... (first-come-first-served)

Members of the scientific community, family, and beyond gathered in celebration at the gala night screening of David Baker's Nobel Prize award ceremony! Watch this space for more pictures and updates.

David Baker visits all the Rosetta folks after his Nobel lecture. And photo of all three Chemistry laureates - David Baker, Demis Hassabis, and John Jumper. An honor to be here in Stockholm to see this.

Rosetta Community watching David get the award! @rosettacommons.bsky.social