New online! De novo design and evolution of an artificial metathase for cytoplasmic olefin metathesis

RFdiffusion2 is now live! github.com/RosettaCommo... You can now design proteins, and in particular enzymes from just partially defined amino acid side chains, and without defining their sequence position or order!

We are happy to share that the code and weights of PLACER (formerly known as ChemNet) are now public! This method allows for rapid evaluation of protein side chain and ligand conformational ensembles, with uses in ligand docking and enzyme evaluation. github.com/baker-labora...