Friedrich Förster
@fridof.bsky.social
📤 330
📥 127
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Structural biologist, Cryo-EM aficionado, signal peptide nerd, teacher, mentor, dad, …
Congratulations Marten! We hope this new version of pytom will be useful to many cryo-ET enthusiasts.
add a skeleton here at some point
4 months ago
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reposted by
Friedrich Förster
Bijvoet Centre
6 months ago
Exciting Bijvoet Seminar by Marie-Eve Aubin-Tam from
@tudelft.bsky.social
on the engineering of bioinspired and living materials!
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reposted by
Friedrich Förster
PfefferCryoLab
7 months ago
Online today at
@naturecomms.bsky.social
and a great opportunity for our first post
@bsky.app
: in a major team effort, we reveal the structural mechanisms for centrosomal recruitment and organization of the human microtubule nucleator γ-TuRC:
www.nature.com/articles/s41...
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Structural mechanisms for centrosomal recruitment and organization of the microtubule nucleator γ-TuRC - Nature Communications
The γ-TuRC plays a central role for nucleation of microtubules at the centrosome. Here, the authors dissect structural mechanisms for centrosomal recruitment and regulation of the γ-TuRC and identify ...
https://www.nature.com/articles/s41467-025-57729-2
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And now to something completely different: the response of an anaerobic archaeon to oxidative stress. Tubular nanocompartments encapsulate virus-like particles! Great work by Wenfei Song and many colleagues from
@bijvoet-centre.bsky.social
and
@mib-wur.bsky.social
.
www.biorxiv.org/content/10.1...
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Structure of an oxygen-induced tubular nanocompartment in Pyrococcus furiosus
Reactive oxygen species (ROS) pose a significant threat to biological molecules, prompting organisms to develop systems that buffer oxidative stress and contain iron, which otherwise amplifies ROS pro...
https://www.biorxiv.org/content/10.1101/2025.03.19.643997v1
6 months ago
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Center for Molecular Medicine at UMC Utrecht is looking for a Principal Investigator in the field of fundamental Cancer Biology! The vacancy states tenure track level, but also candidates with a more advanced career are very welcome to apply.
www.werkenbijumcutrecht.nl/vacatures/we...
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Center for Molecular Medicine
https://cmmutrecht.eu
7 months ago
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reposted by
Friedrich Förster
Ioannis Skalidis
8 months ago
I guess I should have posted a bit earlier, but I'm very excited that my
#MSCA
application got accepted! I'll be working at
@fridof.bsky.social
lab
@utrechtuniversity.bsky.social
to develop my
#teamtomo
skills on my project: Protein ER-ways! Here's to gaining new insights on ER protein biogenesis!
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reposted by
Friedrich Förster
Bijvoet Centre
9 months ago
In one of our first publications in 2025, with colleagues from St. Louis, Leiden and Boston, we shed light on the molecular mechanisms of motile cilia, structures used by cells to propel themselves through fluid or to move fluid across their surfaces.
www.nature.com/articles/s41...
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Structural diversity of axonemes across mammalian motile cilia - Nature
Cryoelectron microscopy, cryoelectron tomography and proteomics are used to resolve the 96-nm modular repeat of axonemal doublet microtubules from both sperm flagella and epithelial cilia of the ovidu...
https://www.nature.com/articles/s41586-024-08337-5
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reposted by
Friedrich Förster
Amrei Bahr
9 months ago
Starkes Signal!! Über 60 dt. Hochschulen & Forschungsinstitutionen haben heute ihren Ausstieg bei X bekanntgegeben, s.u.
#eXit
X sei nicht mehr vereinbar mit ihren Grundwerten: „Weltoffenheit, wissenschaftliche Integrität, Transparenz und demokratischer Diskurs.“ Liste der Beteiligten hier:
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Hochschulen und Forschungsinstitutionen verlassen Plattform X - Gemeinsam für Vielfalt, Freiheit und Wissenschaft
https://nachrichten.idw-online.de/2025/01/10/hochschulen-und-forschungsinstitutionen-verlassen-plattform-x-gemeinsam-fuer-vielfalt-freiheit-und-wissenschaft
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My new life in blue starts with sharing a preprint of amazing Max Gemmer’s ex vivo analysis that sheds light on the machinery responsible for inserting many multispanning transmembrane proteins into the ER membrane
#teamtomo
:
www.biorxiv.org/content/10.1...
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Exploring the molecular composition of the multipass translocon in its native membrane environment
bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution
https://www.biorxiv.org/content/10.1101/2023.11.28.569136v1
almost 2 years ago
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