I'd like to be in cat. 3, but the 1% cut-off locks me in cat. 2.. For me it defeats all possible positive aspects in a dominant negative manner. AI to browse claims across papers would be great. But please avoid quality scores and cut-offs. For one because they focus on words >> data+figure quality

We lost a scientific hero today, Bob Lehman. Here is a 🧪🧵I posted last year about Bob.

The hardest part about proving genocide is "Intent." Israel's fascist defense minister BenGvir just proved again his intent to mass murder everyone in Lebanon, declaring "ALL OF LEBANON MUST BURN." Block arms to Israel. Sanction these war criminals. Any politician denying this is complicit.

Welcome to the Fascist States of America, where the EiC of a leading journal is forcibly removed by police for passing out his own editorial at the annual meeting of the field’s association…because it’s “too political” (read: it calls on scientists to speak out & stand up). We are here. This is it.

TL;DR: We've identified more than 100 cases of apparent manipulation in Thermo Fisher Scientific's antibody verification data. @sholtodavid.bsky.social @johanduchene.bsky.social reeserichardson.blog/2026/05/28/h...

Reposting this from April 1, 2007 in honor of Craig Venter. I did this as an April Fool's joke - sharing it as a PDF. I got stressed when I found out Craig had seen it and knew it was by me. But he loved it and said it was OK to share it more widely. So then I posted it on the web.

Using light-activated CRISPR in zebrafish, we triggered synchronized DNA breaks and track the repair process. ⚡🐟⚡ 

 Well ... DNA repair is very different in embryos compared to tissue culture cells. Embryos repair DNA breaks incredibly fast - within minutes! www.biorxiv.org/content/10.6...

Pollution levels in Paris after 10 years of advancing sustainable transport.

Excited to share our discovery of a new programmable RNA-guided DNA-targeting system hiding inside bacteriophages that predates CRISPR. We call it VIPR (Viral Interference Programmable Repeat), and it uses an entirely new logic to find its targets. Thread + link below.

Having mocked and insulted a billion Muslims on Tuesday, Trump attacked core beliefs of a billion Catholics today. And don’t forget his suggestion that any Jew who didn’t vote for him was an idiot. All in the days between the end of Ramadan, Passover, Easter and Orthodox Easter.

Since our preprint on the ETC-ATP synthase supercomplex has attracted attention, I would like to introduce the platform we used, Langtaosha. It was launched by SMART together with several other institutions with support from Open Life Science Alliance, aiming for long-term open infrastructure 1/4

I hate having to do the "look, they're normal just like us" post, but sometimes you have to do that when American propaganda tries to convince everyone Iranians are "animals".

I'm reviewing Sapiens, one page at a time! It's a little bit fact-checking and a little-bit soul-searching combined into a lot of feelings... ecodevoevo.blogspot.com/2026/03/sapi...

ROCKET 🚀 inference-time optimization of AlphaFold to fit structural data is published! rdcu.be/fa9YH Since our preprint, we’ve pushed it to regimes where other methods break: low resolution, weak signal, real experimental edge cases. Here’s what we learned: 1/15

This! AlphaFold is PDB + UniProt + Deep learning. No data sharing, no curation, no data standards, no AlphaFold.

In memoriam Fazly Ataullakhanov was a biophysicist with a rich heritage, and a strong scientific legacy. An ethnic Tadjik, born in Samarkand (Soviet Uzbekistan), educated in Moscow, made his best scientific contributions in English, collaborating with international researchers in the USA. /1

Congratulations Vladimir and team! A lot more in the paper, just posting some of Figure 2 here since growing and shrinking microtubules on the grid before freezing and cryoET is amazing

A week ago, we had an open conversation amongst senior academics in leadership roles and their use of LLMs (in both their leadership capacities and individually). Small group, not representative, but it already taught me a great deal about the diversity of perspectives (& their consequences). 1/

Lees Huxley.

Our paper is now out in Nature: “Ancient co-option of LTR retrotransposons as yeast centromeres” www.nature.com/articles/s41... A short thread on how retrotransposons helped give rise to yeast point centromeres. 1/14

If you’ve not stopped using Meta products (Facebook, Instagram, etc…), now is a really good time to stop. This is viscerally horrifying.

Let's try this #AcademicSky 1 fav, 1 funny, strange, or unexpected scientific anecdote about a paper, a scientist, a fact, hoping that some will be new to you.

🧪🧬New preprint We present cryo-EM structures of reconstituted CTCF–nucleosome complexes, showing CTCF dimerization drives nucleosome oligomerization into defined higher-order assemblies. Disrupting CTCF–CTCF interfaces in mESCs reduces looping and impairs differentiation. tinyurl.com/CTCF-nucleos...

European Scientists who said NO to Epstein-funding are the heroines of this hour🦸‍♀️ They show: It was your choice to SAY NO to Epstein's $ as scientist- you just had to have ethics & a spine Kudos to Physicist IVETTE FUENTES who said NO She was working at @quantumunivie.bsky.social @univie.ac.at

PhD position in my lab!

We speak to Greek economist Yanis Varoufakis about the United States under Donald Trump and its attempts to reshape the post-World War II international consensus. www.democracynow.org/2026/1/22/ya...

Globally, no single day in 2025 was cooler than its 1991-2020 average. climate.copernicus.eu/global-clima...

"Israel Is Banning the 'Last Foreign Witnesses' to Its Genocide in Gaza" In a likely deadly move, the Israeli government told 37 foreign aid groups, including Doctors Without Borders, they could no longer operate in Palestine. Where is the outrage, asks Diana Buttu for Zeteo?

“For too long, those fluent in the good grammar of civility have deployed decorum to mask agendas of cruelty.”

On Trump being a fascist👇 Video: Aaron Rupar via X (@atrupar)

Big news! Group leader Sascha Martens has been awarded a prestigious @erc.europa.eu Synergy Grant for the collaborative project DegrAbility to explore how cells can better recycle harmful protein aggregates linked to diseases like Alzheimer’s ➡️ tinyurl.com/2zuz9jcf @univie.ac.at @meduniwien.ac.at

Saruman talking. Palantir running. Please help everyone around you to stop paying attention to him and X! If within reach, please alarm employers, politicians, and news agencies (again and again)..

📢 Open Call! The Max Perutz Labs invite applications for a Full Professorship in Integrative Structure Biology with a focus on in situ structural biology using cryo-electron tomography (cryo-ET) and related methods. More details ➡️ tinyurl.com/brswbymu

I have a PhD opening in my lab for an exiting project using base editor screens to find novel drug targets. Please help spread the word. candidate.hr-manager.net/ApplicationI...

The @crick.ac.uk is recruiting Early Career Group Leaders - Lab set-up, research costs, salaries for up to 5 researchers - Support for up to 12 years - Access to our core facilities - Competitive salary - Fantastic colleagues - All areas of biology Deadline 27 Nov www.crick.ac.uk/careers-stud...

WHAT THE F*CK‼️‼️‼️‼️‼️ Chicago’s Reverend David Black of First Presbyterian has been assaulted multiple times by ICE agents during peaceful protest in the city‼️They shot a some kind of non lethal bullet at his head‼️ #PepperBall

I will not back down. Trump is now calling for the arrest of elected representatives checking his power. What else is left on the path to full-blown authoritarianism?

Independent research fellowships leading to tenured positions at the John Innes Centre. Repost = nice. Thank you very much!!!

I can’t quite put it into words yet, but something is happening, a kind of global singularity—a fusion of tech/media/news/government/employment which allows the global elite to push single agendas: “You WILL care about Charlie Kirk. You will NOT care about Palestine. You WILL fear cancel culture.”

#1 Centromeres are epigenetic loci defined by CENP-A, positioned in unmethylated DNA flanked by highly methylated regions. Our work, published in @natgenet.nature.com in collaboration with @naltemose.bsky.social investigates the role of DNAme at human centromeres www.nature.com/articles/s41...

Exciting FULL PROFESSORSHIP at the Vienna BioCenter - Molecular Mechanisms of Disease Mechanisms: www.maxperutzlabs.ac.at/news/open-po... Come be our colleague!

Child mortality used to be 50%. As recently as 1950, 25% of children died globally. Now it’s 4% globally, and 0.3% in some rich countries. A large part of that is better public health and vaccines. Republicans are trying to take us back to the past. ourworldindata.org/child-mortal...

Please re-post: If you know (or are!) somebody who might fancy doing a PhD (Oct 2026 start) in my group @oxfordbiochemistry.bsky.social, working on chromatin evolution in prokaryotes (or other things we're interested in), please have a look at www.bioch.ox.ac.uk/supervisors-...

This will break you

OG FPLC - unexpected suprise hidden in a drawer

Instead of regurgitating the bromide that LLMs are just "autocomplete on steroids" (even by people who know better), maybe we can actually engage in some public education. The problem with genAI is better expressed through a classic computer science concept, known as SYMBOL GROUNDING. 🧵

“Maybe the world won’t act, maybe the world won’t help us but there might be a motive to stop this war—every time I document a massacre or event or bombing, I think that maybe through this bombing or this image that the war could stop and this war would end...”

This is amongst the most impactful two minutes of broadcasting I’ve ever seen. By Emma Murphy, International Editor, ITV News. #Gaza

And another opportunity! Any postdocs looking forward to start your lab on a tenure track? Supportive environment, great core facilities and an outstanding PhD program.