Tal Sharf
@talsharf.bsky.social
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📥 322
📝 13
sharflab.ucsc.edu
reposted by
Tal Sharf
Matteo Carandini
about 2 months ago
Sequences are everywhere! In every brain region. And are written in stone. Invariant Activity Sequences Across the Mouse Brain. Out today, by Célian Bimbard, with
@kenneth-harris.bsky.social
. Based on data by Célian and by
@intlbrainlab.bsky.social
.
www.biorxiv.org/content/10.6...
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reposted by
Tal Sharf
Baskin Engineering at UC Santa Cruz
2 months ago
New research led by
#BaskinEngineering
Prof
@talsharf.bsky.social
suggests the brain might be preloaded with a kind of internal template for reading the world, even before the world reaches us - via
@discovermag.bsky.social
bit.ly/4rFJMx8
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Our Brains May Have Pre-Configured Instructions to Understand the World When We're Born
Discover how brain organoids are helping us uncover whether early thought patterns emerge from experience or are hardwired into our DNA.
https://bit.ly/4rFJMx8
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reposted by
Tal Sharf
Kevin Mitchell
3 months ago
Slate status: not blank
add a skeleton here at some point
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I was told it would take about three years to get a new lab up and running. Nearly three years later, our work on preconfigured neuronal firing sequences in human brain organoids is finally out in Nature Neuroscience:
www.nature.com/articles/s41...
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Preconfigured neuronal firing sequences in human brain organoids - Nature Neuroscience
Examining human brain organoids and ex vivo neonatal murine cortical slices demonstrates that structured neuronal sequences emerge independently of sensory input, highlighting the potential of brain o...
https://www.nature.com/articles/s41593-025-02111-0
3 months ago
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"We can, should, and will use cerebral organoids to discover new medical treatments, study brain development, reduce the demand for animal testing, and even power computers and more energy-efficient AI."
www.vox.com/future-perfe...
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The challenge of creating brains in a lab
Lab-grown brains don’t have to inspire horror.
https://www.vox.com/future-perfect/466758/brain-organoids-lab-grown-conciousness-ai
3 months ago
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reposted by
Tal Sharf
Emily R. Trunnell, Ph.D.
4 months ago
In an NSF-supported study,
@talsharf.bsky.social
and collaborators will investigate the capacity of human brain organoids to learn and adapt, with implications for
#organoid
research,
#bioethics
, and science education.
news.ucsc.edu/2025/10/lear...
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Effort aims to uncover the learning and reasoning potential of brain organoids
The Braingeneers team will to test the ability of brain organoids to solve tasks in real time
https://news.ucsc.edu/2025/10/learning-and-reasoning-potential-of-brain-organoids/
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reposted by
Tal Sharf
Carsen Stringer
about 1 year ago
What if… spontaneous neural activity 🧠reflects the baseline rumblings of a brainwide dynamical system initialized for learning? We find that the rumblings have macroscopic properties like those emerging from linear symmetric, critical systems 🧵
#neuroscience
#neuroAI
www.biorxiv.org/content/10.1...
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Awesome work by
@mrbadash.bsky.social
and the crew at
@ucscgenomics.bsky.social
Goal-directed learning in cortical
#organoids
www.biorxiv.org/content/10.1...
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Goal-Directed Learning in Cortical Organoids
Experimental neuroscience techniques are advancing rapidly, with major recent developments in high-density electrophysiology and targeted electrical stimulation. In combination with these techniques, ...
https://www.biorxiv.org/content/10.1101/2024.12.07.627350v1.full
about 1 year ago
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reposted by
Tal Sharf
Yoshiho Ikeuchi
about 1 year ago
Our manuscript preprint is out!
add a skeleton here at some point
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I’m thrilled to share our revised work on neuronal sequences in brain
#organoids
. It has been an absolute joy to collaborate with an incredible team of talented experimental and computational neuroscientists brought together by this project.
www.biorxiv.org/content/10.1...
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Protosequences in brain organoids model intrinsic brain states
Neuronal firing sequences are thought to be the basic building blocks of neural coding and information broadcasting within the brain. However, when sequences emerge during neurodevelopment remains unk...
https://www.biorxiv.org/content/10.1101/2023.12.29.573646v2
about 1 year ago
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