UChicago Microbiology is searching for tenured or tenure-track faculty working in host-pathogens interactions, viral and bacterial pathogenesis, and emerging infectious diseases. Come join our vibrant Department! microbiology.uchicago.edu Apply here apply.interfolio.com/174404

UChicago Microbiology is searching for tenured or tenure-track faculty working in host-pathogens interactions, viral and bacterial pathogenesis, and emerging infectious diseases. Come join our vibrant Department! microbiology.uchicago.edu Apply here apply.interfolio.com/174404

Congratulations!

Now online! Evolution of Mycobacterium tuberculosis transcription regulation is associated with increased transmission and drug resistance

We are hiring an Assistant Professor of Biochemistry and Biophysics at Weill Cornell Medicine. Come join our collaborative research environment with state-of-the-art facilities in NYC! Application review starts Oct 22. biochem.weill.cornell.edu/join-our-fac...

Congratulations to JEM Editorial Board Co-Chair Carl Nathan on receiving the 2025 David & Beatrix Hamburg Award from @nam.edu for his fundamental work in improving understanding of #InnateImmunity:

Very interesting, excited to see where this goes.

We are hiring! The Dept of Microbiology and Molecular Genetics is looking for faculty at the Assistant or Associate professor level (tenure track). Please consider joining our vibrant microbiology and immunology community at the University of Pittsburgh School of medicine

Applications for faculty positions at Rockefeller are now open! We are seeking exceptional, creative scientists to join our faculty. Learn more below:

Senate committee endorses NIH budget increase, rebuking Trump administration’s proposed 40% cut www.statnews.com/2025/07/31/n...

Congrats to all authors! Very cool mechanism. www.nature.com/articles/s41...

I doubt that there is a single family in America that hasn’t benefitted directly from the NIH.

Thanks for your leadership on this @asm.org. asm.org/articles/pol...

Happy to share the most recent preprint from the lab, the thesis work of Dr. Adam Krebs and a collaboration with many, including the Geissmann lab @mskcancercenter.bsky.social Here is a short paper thread. #tuberculosis #macrophages 🦠 www.biorxiv.org/content/10.1...

"In addition to interrupting lifesaving science, the suspensions will threaten jobs and take money away from universities and their surrounding economies in 10 states representing all regions of the country..."

"In TAG’s view, the suspended TB studies do not pose a substantial risk to the American public in comparison with the clear and present danger of TB, which is the world’s leading cause of death from a single infectious agent." www.treatmentactiongroup.org/statement/tr...

Well done Liam!

The politically appointed NIH deputy director Matt Memoli overrode career staff and the NIAID director to suspend additional projects he deemed risky — mainly about tuberculosis and ones that made the bacterium less dangerous, the WaPo reports.

Exclusive: In response to White House concerns about allegedly risky research on viruses, bacteria, and other pathogens, the National Institutes of Health has begun a crackdown on dozens of studies it was funding, ScienceInsider has learned. scim.ag/44oJIbw

Great work from Horia Todor in Carol Gross's lab showing it's possible to predict complexes in "competition" pools in AF3 resulting in the first all-by-all prediction for a species. After length correcting the ipTM score predicts well known interactions and correlating ipTM vectors also has value.

Reminder for science budget watchers-- House and Senate Appropriations Committees are working on FY26 spending bills to determine NSF and NIH funding. The White House recommended a 57% reduction for NSF and 40% for NIH. But Congress sets the budget. www.ascb.org/science-poli...

Check out our latest issue where we interview @danielkronauer.bsky.social, who studies the evolution and function of insect societies at Rockefeller University. www.cell.com/current-biol...

💥 Very excited to share this review in Nature Reviews Microbiology. Contributing to this review with Val, Digby and Amy was an enlightening experience! Hope people in the community find it useful- we managed to cite around 200 papers... www.nature.com/articles/s41... www.nature.com/articles/s41...

Please apply!

Wanted to highlight our latest preprint--a huge effort by multiple people and labs, but led primarily by @wsdewitt.github.io, Tatsuya Araki, and Ashni Vora, in a very close wet-dry collaboration with @matsen.bsky.social’s lab at the Hutch www.biorxiv.org/content/10.1...

Bacteria encode homologs of the human NACHT proteins that form inflammasomes and use them to defend against phage #infection. @amyconte.bsky.social @aaronwhiteley.bsky.social &co show that bNACHT25 detects diverse phages indirectly through interaction with the host chaperone DnaJ. 🧪 plos.io/4koXP60

How bad will it be? Catastrophic. Proposed cuts to #NSF, #NIH, and #NASA will set the US R&D landscape back 25 yrs+, cause economic and job loss now, and undermine innovations to come. But, this is the WH's *proposed* budget. Speak up now before it is too late. (inflation adjusted $-s below)

Here's the NIH's proposed budget - from $48 billion to $27 billion. NIAID, current ~$7 billion cut to ~$4.2 billion. The proposed 15% cap on indirect costs remains. Again, these budgets are passed, and our leadership in science, technology, and innovation is gone. www.hhs.gov/sites/defaul...

Really excited that our group was able to contribute to this awesome work from Bing Zhang and Zihe Rao solving the structure and assembly of the MmpS5L5 efflux pump from Mtb!! www.nature.com/articles/s41...

All of NIH funding to Northwestern University is frozen. This pause includes noncompeting approved funding, new and competing grants with fundable scores. No reimbursements for money already spent have been received since March. This situation is rarely reported so please Please get the word out!

This isn’t just numbers on a table–it’s my lab and the labs of my colleagues. Terminated grants mean shuttered projects, lost talent, and stalled progress against deadly pathogens. The damage to science–and to public health–is real and immediate. Thanks @peterhotezmdphd.bsky.social for speaking out.

I will be recruiting new postdocs with start dates end 2025 - early 2026. If you'd like to work at the Pasteur Institute in the heart of Paris surrounded by amazing scientists, reach out to discuss possible projects on SynBio / Bacterial Immunity!

Challenging times for biomedical research in the U.S. One of our grants was terminated and two others frozen. Thinking of colleagues from Bethesda to Boston to South Africa who are facing the same uncertainty. Now more than ever, we must speak up for the value of this work.

Simply incredible story of the triumph of the US biomedical research ecosystem. Think of all the strands of discovery over many decades that came together to save this child. In large part becuase of NIH. www.nytimes.com/2025/05/15/h...

This is what can be achieved today due to longstanding federal support of academic basic science alongside close partnership of universities, private industry and NIH intramural initiatives. An ecosystem worth not just saving but doubling down on! innovativegenomics.org/news/first-p...

Congratulations @saehrt.bsky.social. Absolutely thrilled for you and the department! news.weill.cornell.edu/news/2025/04...

Pleased to highlight a new preprint from the lab. This is the work of my longtime collaborator in the lab Allison Fay, who wanated to create new tools for disocvery biology in mycobacteria, specifically a new sysem for protein localizaton and proximity proteomics. www.biorxiv.org/content/10.1...

To sign the petition: www.change.org/p/petition-t...

From Tom Maniatis: www.cell.com/cell/fulltex...

"A human gut bacterium antagonizes neighboring bacteria by altering their protein folding ability" @cp-cellhostmicrobe.bsky.social @yalemedicine.bsky.social Andrew Goodman www.cell.com/cell-host-mi...

Congrats to my colleagues in the Schnappinger, @saehrt.bsky.social, Rubin, and Fortune labs. Great to see this published. www.nature.com/articles/s41...

Congrats all!

OUT NOW - A BCG kill switch strain protects against Mycobacterium tuberculosis in mice and non-human primates with improved safety and immunogenicity www.nature.com/articles/s41...

Interested in Mtb pathogenesis and developing new strategies to treat these deadly infections? Please apply to join us for the GRC for Tuberculosis Drug Discovery and Development!! www.grc.org/tuberculosis... Deadline to submit an abstract to be considered for a talk is March 1st! Please repost!

Congrats Tavazoie lab!

Congrats @stallingslab.bsky.social!

Congrats all!

Happy to share my first ever (co)last author paper 🥳 reporting on how Mtb adapts its carbon diet under acid stress. A big thank you to my partners in crime @saehrt.bsky.social and @healycl.bsky.social without who this would not have been possible 😘 journals.asm.org/doi/10.1128/...

Very cool work. Congrats neighbors! www.nature.com/articles/s41...