...Students will need to develop sufficient expertise to identify when AI systems produce plausible but incorrect outputs — which poses a dilemma because this requires the very skills that AI is starting to replace... www.nature.com/articles/d41...

Proud to share a preprint of our paper on how bridge-like lipid transport protein VPS13C senses lysosomal membrane tension in anticipation of membrane lesions to initiate net ER-to-lysosome lipid transfer for efficient lysosomal repair www.biorxiv.org/content/10.1...

Crick group leaders work across disciplines, supported by core funding and mentoring to build ambitious, curiosity-driven research. Apply now to join us ➡️ www.crick.ac.uk/careers-stud...

🚨 We’re hiring a postdoc! 🚨 Interested in lysosomes, Parkinson’s disease, cell biology, microscopy — or all of the above? Come work with us at the Bonet-Ponce Lab! Reach out directly: [email protected] Learn more: bonetponcelab.com Let’s chat!

New paper - MAPL strikes again! Interested in mitochondrial signalling, inflammation, lysosome biology, pyroptosis, and Parkinson's disease? Have a look, there's something for everyone! Feeling grateful! @mitocollier.bsky.social Funded by #CIHR, @asapresearch.parkinsonsroadmap.org. rdcu.be/eKKz1 🇨🇦

WHO reports 1 in 6 bacterial infections worldwide are antibiotic-resistant, with resistance rising sharply since 2018. Gram-negative bacteria like E. coli and K. pneumoniae pose the biggest threat. Action on #AMR surveillance and responsible antibiotic use is needed. www.who.int/news/item/13...

What an example of courage, resistance and hope. Maria Corina Machado is the winner of the 2025 Nobel Peace Prize. @nobelprize.bsky.social www.nobelprize.org/prizes/peace...

We are inviting applications for postdoctoral fellows in immunology of TB at the South African Tuberculosis Vaccine Initiative, University of Cape Town. For more information see the attached ad: idm.uct.ac.za/media/739223

EXCITING NEWS!! We're searching for a new professor colleague at the Biozentrum🇨🇭. Ideal candidates are exploring novel biological questions with structure, biophysics, or high-resolution imaging. 🧪 🧶🧬 🔬 The call closes Nov 3. Please get in touch if you would like more information. Come join us! 👩‍🔬🤓

Excited to share Wendy Le Mouëllic’s PhD work, now published in @pnas.org! It reveals that M. tuberculosis depends on inorganic sulfate import to survive inside host cells—fueling essential processes such as redox balance and stress resistance. Huge congrats to Wendy & colleagues! shorturl.at/WbFQC

What I would tell my younger self if I could go back in time: enjoy life as in 2025 you will be mostly charging devices, downloading apps and updating software…

🦠 Mycobacteria aren't just tough, they're interior designers! 🦠 Check out our latest #preprint 🚨, led by our PhD student @camimille.bsky.social , where we show that #Mycobacterium tuberculosis builds secret cytoplasmic membranes to adapt its metabolism and sneak past immunity 🤫 Thread coming soon!

Watch @maxgg.bsky.social, Group Leader at the Crick, as he explains what happens to cells that are infected with tuberculosis and how his lab is studying our bodies’ response to this infection. www.youtube.com/watch?v=VWCt...

Thrilled to share the first story from my postdoc! 🎉 A wonderful experiment + simulations collaboration. In the Drosophila wing, we find that 3D cell shapes affect signalling range and fine-tune developmental patterning www.biorxiv.org/content/10.1... Thread below ⬇️

A first-in-class cell-wall biosynthesis inhibitor in #TB www.nature.com/articles/s41...

Very excited to announce that my first, first author paper, is now on BioRxiv! In this paper we unambiguously show #COPII coated vesicles in unperturbed human cells for the very first time!! Make my day and check it out! www.biorxiv.org/content/10.1... #Cryo-ET #TeamTomo #Cryo-CLEM ❄️🔬❄️🔬❄️🔬❄️🔬

Happy to share the most recent preprint from the lab, the thesis work of Dr. Adam Krebs and a collaboration with many, including the Geissmann lab @mskcancercenter.bsky.social Here is a short paper thread. #tuberculosis #macrophages 🦠 www.biorxiv.org/content/10.1...

📢 Open Call! The Max Perutz Labs invite applications for a Tenure-Track Professorship in Mechanistic Cell and Developmental Biology. More details ➡️ tinyurl.com/3fbkp89c

Meet the new Editor in Chief of mSystems journals.asm.org/doi/10.1128/...

Newest paper from the lab out today (doi.org/10.1084/jem....)! Here, we describe PathMHC, a novel MS-based approach to identify rare pathogen-derived peptides on MHC-I and MHC-II. We apply this to a range of pathogens Mtb, SARS-CoV-2, and Listeria.

The magic of Mafalda by the great Joaquin Lavado (Quino)- the mendocino did indeed galvanised a generation @newyorker.com Lahttps://www.newyorker.com/magazine/2025/07/07/the-argentinean-comic-strip-that-galvanized-a-generation

📣 We’re recruiting 1-2 Group Leaders! NCMBM is looking for early-career researchers ready to establish their independent research groups! 🧬 With an attractive start-up package, help us shape the future of molecular biosciences and medicine in 🇳🇴 and be part of the @nordicembl.bsky.social!

Thrilled to share that our "Poster at a Glance" on #Phagocytosis is out! Thank you @jcellsci.bsky.social @biologists.bsky.social for the invitation ! Prepared with @manondepierre.bsky.social @chiarapompili.bsky.social from @institutcochin.bsky.social journals.biologists.com/jcs/article/...

🔬Calling all microbiologists. 🔬 Ever feel like your paper is too small for some journals, but too solid to sit on? #FEMSMicrobes welcomes well-executed microbiology manuscripts, and they put special attention on promoting ECR authors, eg the webinar below. 👇 @femsjournals.bsky.social @femsmicro.org

💥 Very excited to share this review in Nature Reviews Microbiology. Contributing to this review with Val, Digby and Amy was an enlightening experience! Hope people in the community find it useful- we managed to cite around 200 papers... www.nature.com/articles/s41... www.nature.com/articles/s41...

🎯 New antibiotic target in TB! 👉 Small-molecule inhibitor targeting PurF, the first enzyme in the mycobacterial de novo purine biosynthesis pathway. 👉 Effective vs drug-resistant Mycobacterium tuberculosis in vivo (in mice) #TBSky #IDSky #MedSky 🧪 @nature.com www.nature.com/articles/s41...

How innate immunity starts? Early embryos eliminate bacterial infections by epithelial phagocytosis, a conserved process from zebrafish to human embryos. Check our story: www.cell.com/cell-host-mi...

‼️ Save the date! ‼️ Tuberculosis: Understanding the Disease Across Scales Keystone 2026 on March 23-26 in Cape Town, South Africa 🇿🇦 Very excited to organise this meeting with Digby, Bree and Margarida Short Talk Abstract Deadline: Nov. 24, 2025 www.keystonesymposia.org/conferences/...

My Canadian university, Queen's, is offering TWENTY 4-year funded PhDs (40k CAD/yr) for a student of ANY citizenship who has been accepted at a top 100 US university but have had offer rescinded OR are reconsidering offer due to US policy. Details found here👇 www.queensu.ca/grad-postdoc...

My lab studies bacterial infections. We spend a lot of time looking at (or for) species-specific genetic and genomic databases for hosts and microbes. FlyBase is the best of all—there is literally no comparison. Its existence is under threat. Please donate. www.philanthropy.cam.ac.uk/give-to-camb...

First day of the UK Cellular Microbiology Network #UKCellmicro2025 in Bush House @kingscollegelondon.bsky.social Excellent organisation by @codendall.bsky.social @vintorraca.bsky.social @peterwshill.bsky.social @jwanford.bsky.social exciting science, friendly community and wonderful views

Important changes on @erc.europa.eu grants‼️Grant structure & most importantly eligibility timeframes (10 years for starting, 15 years for consolidator post PhD-but you can have them only once) changes: erc.europa.eu/news-events/...

Check out our latest preprint! We show that the same antibacterial toxin requires different immunity proteins depending whether it’s intra or extracellular

Updates on our keynotes We’re delighted to open the meeting with Prof Stuart Neil (KCL). On Day 2, we continue with Prof Jose Bengoechea (LSHTM). Both Prof Neil and Bengoechea have been outstanding mentors throughout their careers. We hope our ECRs will take the opportunity to interact with them!

'If successful, it would be the first new class of antibiotic capable of killing acinetobacter or any other “Gram-negative” bacteria to be developed for more than 50 years. This type of bug has a structure that makes it more difficult to treat.' www.ft.com/content/1f94...

This. 👇

Excited to announce our paper on ancient Borrelia genomes is finally out! 🦠💀We document the evolutionary history of louse-borne relapsing fever, published today in @science.org‬ with @lucyvandorp.bsky.social and @pontus-skoglund.bsky.social #aDNA 🏺🧪🧬 Main findings and paper below: 🧵⬇️

Huge congratulations to @hbelda.bsky.social and David Bradley for their publication on the extraordinarily interesting FIKK kinase family (I am biased) of the malaria causing parasite Plasmodium falciparum. 1/n

🚨 📢 I’m #hiring!!! I am looking for an experienced #metabolomics scientist with a particular focus on LC-MS. Please follow the link below for more details and how to apply! 📢 🚨 Applications close at 23:59 on May 23rd!!! www.crick.ac.uk/careers-stud...

The KnuepferLab is hiring! Our team is looking for a highly motivated, experienced molecular parasitologist to expand our group as a postdoctoral researcher at the RVC. Follow either link below for more information on the project and the job offer: lnkd.in/eprgmaE9 www.jobs.ac.uk/job/DMY962/p...

Our latest paper is out! Congratulations to @leaswistak.bsky.social et al for this amazing #cryoET work that elucidates the initial stages of #T3SS dependent vacuolar damage during #Shigella infection. We will do a deep-dive later! journals.plos.org/plosbiology/...

Happy to share Saurabh's latest review on the bacterial exometabolome and its role in virulence and pathogenesis, just out in @cp-trendsmicrobiol.bsky.social — and it’s open access! 😉 👏 @saurabhchugh09.bsky.social www.cell.com/trends/micro...

Lead author @ssmelyansky.bsky.social spearheaded a strategy to label a single sulfur-containing glycan called ManLAM on the cell envelope of the bacteria that cause #TB. news.mit.edu/2025/new-mol... or here: www.pnas.org/doi/10.1073/... 🧪 #glycotime @mitchemistry.bsky.social

Officially in third winter

#Tuberculosis prevention and care relies heavily on international donor funding in many settings. In our latest preprint, we examine the potential impact of reductions in international donor funding for #TB - by the US and by other major donor countries. 1/8 www.medrxiv.org/content/10.1...

1/ Today we spotlight @sanchoshimizu.bsky.social, a postdoc in our Paris branch from 2006-12 and now Reader/Associate Professor at @imperialcollegeldn.bsky.social in the department of infectious diseases and head of both of a lab there and a satellite lab at the @crick.ac.uk

Reporting in Nature, Eitan Yaffe and colleagues demonstrate that resistance to an antibiotic can rapidly emerge in commensal gut bacteria in vivo, and that such resistant lineages can persist for a long period following cessation of the antibiotic. 👇 🧪 www.nature.com/articles/s41...

An amazing opportunity for a postdoc! 👇👇

Interested in T cell immunity in TB? Check out our new pre-print on antigen-agnostic identification of generalisable human in vivo Mtb-reactive T cell responses: www.biorxiv.org/content/10.1... with @qimmuno.bsky.social & @innate2adaptive.bsky.social