How will population shifts affect the future burden of #AMR? 👶👩‍🦳 🧫 We use a new modelling framework to explore future projections of #AMR by age and by sex, as well as interventions for control, building on our earlier findings that AMR isn’t uniform across demographics. doi.org/10.1371/jour...

When fluoroquinolone resistance status is unknown, empirical use of BPaLM (adding moxifloxacin to BPaL) is cost-effective as a replacement for BPaL even with high fluoroquinolone resistance levels! 🦠💊 doi.org/10.1371/jour...

Our framework that informed the @who.int TB & climate change policy brief out now in @lancetrespirmed.bsky.social, exploring the intersections and implications of climate change for the TB epidemic. Key message? TB should be considered a climate-sensitive disease www.thelancet.com/journals/lan...

It was a real pleasure to deliver this Introduction to TB Modelling workshop for representatives from Kenya’s National TB, Leprosy and Lung Disease Programme last week with great discussions about how modelling can be used in policy and programme decisions.

Understanding patterns of #TB exposure and transmission is needed for targeted prevention strategies. In our latest pre-print, @petedodd24.bsky.social and I estimated the proportion of TB exposure to and transmission from sex and age groups for 177 countries. bit.ly/4nbV492

In a new preprint (NOT PEER REVIEWED) we continue to explore the challenge of overtreatment in community screening. It seems the benefits of TB treatment far outweigh the harms, especially once we accept that sputum culture is not perfect. Important food for thought. www.medrxiv.org/content/10.1...

PhD opportunity: New approaches to modelling TB transmission in low-incidence settings. Supervised by Ellen Brooks-Pollock (Bristol), me (Bath) & Rajeka Lazarus (Bristol) Apply: www.findaphd.com/phds/project... Deadline 20 Oct #PhD #Tuberculosis #Epidemiology #InfectiousDisease

Our systematic review of rural/urban differences in #TB prevalence shows evidence of rapidly urbanising epidemics in many settings, with differences across countries and regions. Link to preprint below ⬇️

Sad (but not surprised) to read the latest Global Health 50/50 report, amidst turmoil in global health, erosion of democracy, withdrawal from multi-lateralism, aid cuts, attacks on science, DEI, human rights @kentbuse.bsky.social @jocalynclark.bsky.social global5050.org/2025-report/

Men are more than twice as likely as women to have prevalent #TB. We did updated meta-analysis including over 4million people in 99 surveys. Despite increasing focus on gender equitable TB responses, this gap has widened since we last assessed these data over a decade ago.

1/ It’s been 10 years (😮) since we reported that #TB prevalence was twice as high in men as in women. 📢 Our new preprint explores how sex differences have shifted with more recent national prevalence surveys and growing attention to #gender responsive TB prevention and care. bit.ly/4gqP1LH

Fantastic work from @aschwalbc.bsky.social now out in @plosglobalpublichealth.org. Check out his thread below for more details!

Nutritional status is a key determinant of TB. In this updated systematic review and dose-response meta-analysis (43 cohorts inc > 26 million people) we redefined the relationship between body mass index (BMI) and TB. doi.org/10.1093/ije/...

At a time when global resources for #TB research, development, prevention, and care are limited, which interventions should be prioritised in high burden settings? 📢 Our new pre-print compares the impact, cost, and cost-effectiveness of 9 TB interventions in 3 countries. 1/n bit.ly/3V3vXth

📯 New research from @kchorton.bsky.social and colleagues from @lshtm-tbmod.bsky.social! #TB incidence can rebound after community screening ends, meaning the gains made during a program can be erased in the years that follow. This highlights a major challenge in sustaining impact #EndTB #EpiSky

Community screening for #tuberculosis could extend the reach of #TB services, but evidence on its effectiveness is limited. In our latest preprint, we examine the epidemiological impact of trade-offs in diagnostic algorithm, population coverage, and duration of screening. 1/n bit.ly/3UK7pFD

Absolutely BRILLIANT animations and sensible explanations to illustrate just why and how people twist data regarding vaccines and putative links with autism. Do read.

New WHO policy brief on #TB among populations at high risk and people in vulnerable situations includes (for the first time!) "men in settings where health care access is not tailored to their needs". www.who.int/publications...

Our new study examines social contact patterns in urban, peri-urban, and rural communities and their implications for #TB interventions like household contact tracing, infection prevention, and cluster RCTs. #MedSky #EpiSky #IDsky #TBSky Read more in @plosglobalpublichealth.org

“Where are all the men? We need to change the narrative… We need a whole population approach that includes everyone.” - @who.int’s Morkor Newman Owiredu discussing the importance of having a family-orientated approach to achieve triple elimination. #IAS2025

Reduced international donor funding through not only the termination of #USAID, but also announced reductions in donor pledges to #TheGlobalFund from other countries, could lead to substantial potential impacts on #TB morbidity and mortality. Read how in our new study in @lancetgh.bsky.social 👇

Our work estimating the potential impacts of reductions in international donor funding for #TB is now out in @lancetgh.bsky.social: bit.ly/3TDl28T @raclark18.bsky.social @cfmcquaid.bsky.social @alexandra-richards.bsky.social @top-j.bsky.social @reinhouben.bsky.social @richardwhite321.bsky.social

In our latest personal view in @lancetrespirmed.bsky.social, we argue for the inclusion asymptomatic #tuberculosis in vaccine trial endpoints to potentially reduce the size, length, and cost of trials. doi.org/10.1016/S221... @lshtm-tbmod.bsky.social @tb-lshtm.bsky.social

New systematic review led by @hannahrickman.bsky.social shows annual risk of Mycobacterium #tuberculosis conversion in men and women diverges during adolescence and remains higher among men throughout adulthood. www.thelancet.com/journals/lan...

In the 1980s, many thought tuberculosis was on the path to elimination. In reality, more were dying from the disease than ever. The second article in our series on Tuberculosis: ourworldindata.org/the-end-of-t...

Tuberculosis (TB), an infectious disease caused by bacteria, was responsible for as many as one-quarter of all deaths in the US and Europe during parts of the 18th and 19th centuries. However, as we see in the chart for England and Wales, deaths from TB have declined dramatically in rich countries.

🚨We can't lose this fight!🚨 The US gov has historically been the world's largest donor to global health. We cant afford for Congress to pass this rescissions package, which would permanently claw back funds from programs & nations that desperately need them. Call your reps! www.youtube.com/watc...

Tuberculosis still kills around 1.3 million people every year. It was once a massive killer in Europe and the US, but not anymore. How did these countries manage to tackle it? Our first article on TB in a three-part series: ourworldindata.org/tuberculosis...

How bad will it be? Catastrophic. Proposed cuts to #NSF, #NIH, and #NASA will set the US R&D landscape back 25 yrs+, cause economic and job loss now, and undermine innovations to come. But, this is the WH's *proposed* budget. Speak up now before it is too late. (inflation adjusted $-s below)

On #WorldNoTobaccoDay, The Union stands with the tobacco control community in calling on countries to urgently accelerate action. 📈 Raise tobacco taxes 🚭 Ban smoking in public places 🛑 Stop tobacco industry interference 🔗 Read more: theunion.org/news/tobacco... #UnmaskTheAppeal

TB & climate change: @who.int report out now, building on an analytical framework we developed to explore the intersections and implications for the TB epidemic. Key message? TB should be considered a climate-sensitive disease www.who.int/publications...

🎉 Celebrate 25 years of the Introduction to Infectious Disease Modelling course @lshtm.bsky.social in June! 🎉

In response to the Executive Orders issued by the White House affecting scientific researchers in the USA and globally, this new Editorial in European Science Editing calls for Editors and journals to adhere to established scientific consensus and evidence-based practices doi.org/10.3897/ese....

Are you interested in #TB and have experience in #modelling infectious diseases? Come join us in the TB Modelling Group at #LSHTM! We're advertising for a 1 year Research Fellow position, with a closing date of 30 May 2025 👉 jobs.lshtm.ac.uk/vacancy.aspx...

New pre-print on perceptions of #gender equitable norms and #TB testing history in Malawi, led by @elizabeth-digi.bsky.social with @esnightingale.bsky.social @petermacp.bsky.social Helena Feasey, Rebecca Soko, Vincent Phiri, Liz Corbett @kchorton.bsky.social www.medrxiv.org/content/10.1...

Males experience higher rates of illness and mortality from hypertension, diabetes, and HIV/AIDS, and are less likely to seek care compared to females in many countries, highlighting persistent health inequities. doi.org/g9g5ps

#Tuberculosis prevention and care relies heavily on international donor funding in many settings. In our latest preprint, we examine the potential impact of reductions in international donor funding for #TB - by the US and by other major donor countries. 1/8 www.medrxiv.org/content/10.1...

Modelling projects the devastating impacts of US funding cuts, including our estimates of #TB incidence and deaths @lshtm-tbmod.bsky.social @tb-lshtm.bsky.social

“ The United States spent roughly US$12 billion on global health in 2024. Without that yearly spending, roughly 25 million people could die in the next 15 years…” www.nature.com/artic... 1/2

𝗣𝗵𝗗 𝗙𝗲𝗹𝗹𝗼𝘄𝘀𝗵𝗶𝗽 𝗢𝗽𝗽𝗼𝗿𝘁𝘂𝗻𝗶𝘁𝘆(𝗥𝗲𝗳: 𝗭𝗜𝟮𝟱𝟬𝟭) Applications are now open for a fully-funded CREATE PhD Fellowship at Zvitambo in partnership with @qmul.ac.uk , @ucl.ac.uk. Support the Co-SAM trial on recovery from severe acute malnutrition in 🇿🇼 🇿🇲 🇰🇪. Apply by 30/04/25 www.create-phd.org/post/phd-fel...

Critical work showing the deadly effects of misguided cuts to TB care and research. Every impact will be multiplied for years to come since TB infection can remain dormant for years, decades. Less treatment now means more deaths now & more sickness and death for generations.

Did you miss @tb-lshtm.bsky.social & @ucltb.bsky.social Symposium? Or would you like to watch again? Good news: the full recording is now available! tinyurl.com/bdh8fymx @sedonasweeney.bsky.social @kchorton.bsky.social @reinhouben.bsky.social

New pre-print modelling impact of US funding cuts on HIV, #TB, MCH and family planning. We estimate impact of termination of US funding to NTPs via #USAID & The Global Fund may lead to 2.2 (1.5-2.9) million excess TB deaths between 2025 and 2040, reversing over a decade of progress. bit.ly/4lowp18

Our latest pre-print led by @alexandra-richards.bsky.social shows that improving #TB treatment coverage among men to the level achieved among women could reduce morbidity and mortality in men, women, and children. Further evidence of the need for gender-responsive TB prevention and care!

When I was a student, my dream was to work for CDC. I'm extremely proud of the years I spent doing so, and I'm devastated for the brilliant and dedicated public servants who have been affected and for the impact this will have on public health - in the US and around the globe.

For a presentation I am giving, I made a wordcloud of the titles of the NIH grants that were canceled. It is clear about the unscientific goals of this administration

Undernutrition is the leading risk factor for TB globally, so its very exciting to see this roadmap for integrating nutrition into the care of people with TB out now in @lancetgh.bsky.social, led by the amazing @tbtakenseriously.bsky.social www.sciencedirect.com/science/arti...

US-funded organisations are under pressure from executive orders and being forced to choose: stand by #equality and #DEIA or safeguard their funding. Read our latest Report to see the full findings: bit.ly/41su24n #RollbackandResistance #Inclusion

👋LSHTM First & Next Generation Scholarships opportunities 12 #scholarships available across our intensive & distance learning programmes to enable talented #students from underrepresented backgrounds at #postgraduate level to study at LSHTM. www.lshtm.ac.uk/study/fees-a...

1 week today until our World TB Day Symposium! Join us in-person (more tickets available) or online.