New pre-print with @wtmatlock.bsky.social!!! www.biorxiv.org/content/10.6... What shapes the distribution of plasmids across bacteria? Our paper shows that conjugative plasmids actually have a very narrow distribution compared to mobilizable plasmids. Conjugative systems restrict plasmid transfer!

📢📢📢Lectureships at Bristol!📢📢📢 We're hiring 3 x lecturers (=assistant professor) in Biological Sciences, across the discipline. Great department, great colleagues, great building, great city Details here: www.bristol.ac.uk/jobs/find/de...

1/📢 In our new publication, we estimate that in 2022, 134 million people worldwide had a recent Mycobacterium tuberculosis (Mtb) infection and were at high risk of progressing to TB disease. Read the full paper in PLOS Medicine (tinyurl.com/mtbinfection). #TBSky

New research article Sex-based differences in #Plasmodium infection in the control groups of controlled human malaria infection trials in #malaria naive populations in the USA and the Netherlands: a pooled analysis www.thelancet.com/journals/lan... #IDSky #ClinMicro #CHIM #OpenAccess #OA

Agree! super and so well organised thanks @microbiologysociety.org. Great to reconnect with @whelanfj.bsky.social and have a lovely dinner with new colleagues @padpadpadpad.bsky.social @paulhoskisson.bsky.social @magdalenakurteu.bsky.social

Excited to be in cold sunny Liverpool for #microevo25. Looking forward to an interesting day of microbial evolution talks! @microbiologysociety.org

@lshtm-tbmod.bsky.social is offering multiple PhD opportunities through MRC LID, deadline 14 Jan. More details: mrc-lid.lshtm.ac.uk/applicants/ Projects include #1 TB & screening #2 TB & climate change #3 TB & vaccines #4 TB & influenza #5 TB & prevention @cmmid-lshtm.bsky.social @lshtm.bsky.social

Join us for LSHTM’s Equity in AMR Action seminar, which explores how equity influences responses to AMR. Speakers will share their work from the WHO, LSE, and the Global Strategy Lab. 📅 12 Dec ⏲️ 13:00 GMT Check the event details 👇 www.lshtm.ac.uk/newsevents/e...

#Klebsiella infections are a serious & growing #PublicHealth threat For #AntimicrobialAwarenessWeek, @josebengoechea.bsky.social discusses the dangers of bacterial infections, antimicrobial resistance & the global efforts to tackle it. @lshtmamrcentre.bsky.social www.lshtm.ac.uk/newsevents/e...

All are welcome to join the Gender Equity in TB Working Group today at 12:30 in Room B4B @theunion.org! We'll share updates on working group activities and host a panel discussion on progress to date and ways forward to ensure an equitable and inclusive #TB response.

#AMR #Klebsiella cause >100,000 neonatal deaths globally each year. Our new preprint shows more than half of #Klebsiella pneumoniae neonatal sepsis cases in African and South Asian are nosocomial, acquired through transmission in neonatal units. #WAAW doi.org/10.1101/2025...

Why is the only statistical difference in resistant BSI by sex in the 15 to 44 age group where resistance was higher in females (21.4% vs 18.9%, 8.5 vs 5.5 per 100,000 population).....? 👩‍💻🤔 latest #ESPAUR report on AMR just out!

Ahead of #WAAW2025, learn how our researchers are tackling AMR across 30 countries globally, spanning biology, clinical science, policy, modelling, and social sciences. Stay updated on our research, insights, & AMR action. Sign up for our newsletter: bit.ly/3X0SvvO

London interdisciplinary #PhD position now open with myself, @sergemostowylab.bsky.social, & @gmknght.bsky.social on #phage -bacteria-host immune dynamics for WHO priority bacterial pathogens #Klebsiella, #Shigella, and #Staph. Combines cellular microbiology, genomics, & mathematical modelling.

Excited to say that we have a PhD project out on our age-sex research - looking at combinations of #AMR. With the fabulous @jodi-lindsay.bsky.social and Lanre Edun! Do get in touch for more information! mrc-lid.lshtm.ac.uk/2026-27-proj...

Drug-resistant infections in Europe set to rise as populations age, study suggests @gmknght.bsky.social & Catrin Moore explain understanding demographics & infection trends will help design more effective ways of controlling & preventing drug-resistant infections. www.lshtm.ac.uk/newsevents/n...

How will population shifts affect the future burden of #AMR? 👶👩‍🦳 🧫 We use a new modelling framework to explore future projections of #AMR by age and by sex, as well as interventions for control, building on our earlier findings that AMR isn’t uniform across demographics. doi.org/10.1371/jour...

Agata Pacho and I published an article on self care and UTIs/AMR this week! In Sociology of Health and Illness: onlinelibrary.wiley.com/doi/10.1111/.... @lshtmamrcentre.bsky.social

PhD opportunity in my lab: exploring how commensals and pathogens build biofilm communities on endotracheal (ventilator) tubes. Microbial ecology, medical microbiology and fancy imaging! Co-supervised with the fabulous Saskia Bakker and Jeremy Webb warwick.ac.uk/fac/cross_fa... #MicroSky

🚀 Exciting news! Our Centre Director @katholt.bsky.social will be speaking at #AMR2026 on “AMRrules: Interpretive Standards for AMR Genotypes.” Don’t miss her insights🧬✨ 📅 23–25 March 2026 🔗 bit.ly/3SWzJUm #MicroSky #AMR #Genomics

Understanding patterns of #TB exposure and transmission is needed for targeted prevention strategies. In our latest pre-print, @petedodd24.bsky.social and I estimated the proportion of TB exposure to and transmission from sex and age groups for 177 countries. bit.ly/4nbV492

I don't want to seem too cynical, but I wrote this 4 years ago: "...it will come as little surprise if a similar report in a year's time will be almost indistinguishable from the current version." www.thelancet.com/journals/lan...

Great to see accounting for age and sex in the #AMR estimates from the latest WHO #AMR global burden report out today! www.who.int/publications...

In a new preprint (NOT PEER REVIEWED) we continue to explore the challenge of overtreatment in community screening. It seems the benefits of TB treatment far outweigh the harms, especially once we accept that sputum culture is not perfect. Important food for thought. www.medrxiv.org/content/10.1...

Sepsis claims a life every 3 seconds. Ahead of #WorldSepsisDay, @jhenryc.bsky.social @lshtm.bsky.social shares 5 Facts × 5 Actions to tackle sepsis 🩺 & AMR 🦠—from empowering frontline workers 👩‍⚕️ to strengthening diagnostics 🔍 & integrating national response plans 🌍 👉 bit.ly/3Vh4NiG

Congratulations to Jody Phelan for receiving the prestigious @esmyco.bsky.social Gertrud Meissner Award for his groundbreaking work on drug resistant tuberculosis 👏🌍 Read more 👉 bit.ly/4mfGDjW

Been thinking about bedaquiline resistance in TB a lot lately... and today I was wondering about other mathematical models... so I went back to this figure that I still love from a few years ago showing how in #AMR #TB modelling showing most is just RR-TB - lots to be done!

Unfortunately, we're going to have to reschedule this talk - if you have a free hour then do go back and check our some of our past seminars across the #AMR disciplines! www.lshtm.ac.uk/research/cen...

Really looking forward to hear this high level overview of #AMR policy from a great female scientist! Tomorrow - UK - lunch time 👩‍💻

A Friday reminder of this talk next Wednesday. I'm looking forward to welcoming our students to the @lshtm.bsky.social @lshtmamrcentre.bsky.social #AMR short course and then having this seminar from Prof Dame Sally Davies!

In our latest personal view in @lancetrespirmed.bsky.social, we argue for the inclusion asymptomatic #tuberculosis in vaccine trial endpoints to potentially reduce the size, length, and cost of trials. doi.org/10.1016/S221... @lshtm-tbmod.bsky.social @tb-lshtm.bsky.social

LSHTM's Director writes to UK Government about #Gaza public health catastrophe Professor Liam Smeeth's letter to the Prime Minister & Foreign Secretary urges action to prevent a greater #PublicHealth disaster: 👉 www.lshtm.ac.uk/newsevents/n...

I'm super happy to share this preprint on ‘Distribution of capsule and O types in #Klebsiella pneumoniae causing neonatal sepsis in Africa and South Asia: meta-analysis of genome-predicted serotype prevalence and potential vaccine coverage’ doi.org/10.1101/2025...

One week left to submit your abstract to @microbiologysociety.org meeting on “Understanding and Predicting Microbial Evolutionary Dynamics” at Liverpool 26-27 November Lots of spaces for ECR talks and posters! microbiologysociety.org/event/societ...

The complexity of #AMR is rarely understated but few studies tackle the selection vs. transmission challenge. That's what makes this this analysis from 2020 led by @juliethebatgirl.bsky.social so great - look how much could be done with well linked hospital data ... doi.org/10.7554/eLif....

In this blog, our Student Liaison Officer @lshtm.bsky.social, Brandon Hill, explores the often-overlooked intersection between #AMR and #LGBTQ+ health, highlighting the need for more inclusive data and policies to address health inequities. Read more 👇 bit.ly/3HYkp7e

Great to see this review of modelling for IPC & healthcare epi. - we had great discussions at the Think Tank! Key points: determine pathway to infection, make sure the model fits to data then can use it to lead to evidence development on interventions 👩‍💻🏥 pubmed.ncbi.nlm.nih.gov/39228083/

So great to see this 🦣 effort finally published! Massive congratulations to Nichola Naylor (#AMR economist extraordinaire) and the rest of the team! Do check out the amazing resources behind this estimates that can be used for other economic assessments for #AMR. gh.bmj.com/content/10/6...

Great combination of modelling and experimental data to better understand dynamic antibiotic exposure and #AMR And "fitness seascapes" 🌊 doi.org/10.1126/scia...

Get your travel vaccines! 🌏💉 Typhoid vax is very effective BUT only lasts a few years so think about it EVERY time you travel. Most cases are antibiotic resistant, so don’t think you can just take a pill 💊 if you get sick. More and more, resistant cases need hospitalisation & intravenous antibiotics

Very excited for this event on the 9th July! It's part of our #AMR short course but open to everyone as it's online. Do join in and here what the amazing Prof Dame Sally Davies has to stay on the current status of global action on #AMR! @lshtmamrcentre.bsky.social

🎙️ Join Prof Dame Sally Davies, for an insightful seminar on global action against AMR. In this seminar, she will share updates on the UN High-Level AMR agenda, the evidence panel & what’s next for global policy. 📅 9 July 2025 🕰️ 13:00 BST 📍 Online 🔗 bit.ly/4kVSVgP

Excited to share the first beta release of AMRrules at #ABPHM! (Poster 42 tonight) interpretamr.github.io/AMRrules

Researchers at @lshtm.bsky.social, led by @josebengoechea.bsky.social, will conduct a £2.2M study funded by UK MRC to investigate how Klebsiella pneumoniae silently colonises the gut before causing deadly infections. 🔬🦠 Read more 👉 bit.ly/4mNSreh

Great to see this coming out - phage have such potential but there are also many dynamics that we don't understand (and need to model!) and the specificity will always be a complexity....

THREAD: We recently heard that the Trump administration was leaning on the government of Gambia to help Elon Musk. For weeks, our team made phone calls, wrote letters and knocked on folks’ doors to try to confirm it. But we were stuck. So our reporters got on a plane to Banjul. 1/

#Tuberculosis prevention and care relies heavily on international donor funding in many settings. In our latest preprint, we examine the potential impact of reductions in international donor funding for #TB - by the US and by other major donor countries. 1/8 www.medrxiv.org/content/10.1...

📣 🎉 Congratulations to Ms Gladys and @msmicrobiocode.bsky.social on winning our 2025 Publication Prize at @lshtm.bsky.social 🏆 Read more about their winning papers and impactful AMR research🔬 👇 bit.ly/4iM7uCh

Sarah Fortune’s groundbreaking research on tuberculosis—the deadliest disease in the world—based at Harvard Chan School, is among a number of research enterprises in jeopardy due to federal funding freezes targeted at Harvard University and other research institutions.

Another great #ESCMIDGlobal - though mainly for the interesting catch ups leading to inspiring ideas. Lots on S. aureus. Not enough modelling. Some great stuff coming out of @WHO #AMR team. Great session on sex differences in outcomes. But…. nonexistent childcare options!