@lshtm-tbmod.bsky.social is offering multiple PhD opportunities through MRC LID, deadline 14 Jan. More details: mrc-lid.lshtm.ac.uk/applicants/ Projects include #1 TB & screening #2 TB & climate change #3 TB & vaccines #4 TB & influenza #5 TB & prevention @cmmid-lshtm.bsky.social @lshtm.bsky.social

What’s a #UnionConf without the TB modelling course? Packed room again for a long day of intro to modelling. @lshtm-tbmod.bsky.social @tb-mac.bsky.social #WCLH2025 #TBSky

The most important news of the day. #TBSky

New comment: Tuberculosis and undernutrition: improving estimates to reinforce the policy imperative www.thelancet.com/journals/lan...

When fluoroquinolone resistance status is unknown, empirical use of BPaLM (adding moxifloxacin to BPaL) is cost-effective as a replacement for BPaL even with high fluoroquinolone resistance levels! 🦠💊 doi.org/10.1371/jour...

5 million of them are about research

Understanding patterns of #TB exposure and transmission is needed for targeted prevention strategies. In our latest pre-print, @petedodd24.bsky.social and I estimated the proportion of TB exposure to and transmission from sex and age groups for 177 countries. bit.ly/4nbV492

In a new preprint (NOT PEER REVIEWED) we continue to explore the challenge of overtreatment in community screening. It seems the benefits of TB treatment far outweigh the harms, especially once we accept that sputum culture is not perfect. Important food for thought. www.medrxiv.org/content/10.1...

Are there more people with #TB in cities or rural areas? In a 🚨new🚨 preprint (NOT PEER REVIEWED) we modelled urban-rural TB trends from 2000-2023 in 26 countries with 4.6 billion people. www.medrxiv.org/content/10.1...

Our systematic review of rural/urban differences in #TB prevalence shows evidence of rapidly urbanising epidemics in many settings, with differences across countries and regions. Link to preprint below ⬇️

1/ It’s been 10 years (😮) since we reported that #TB prevalence was twice as high in men as in women. 📢 Our new preprint explores how sex differences have shifted with more recent national prevalence surveys and growing attention to #gender responsive TB prevention and care. bit.ly/4gqP1LH

Still trying to figure out what MAHA hates more: women or vaccines.

We must unite against those who seek to divide us.

Our work on modelling population-wide screening in Viet Nam is now available in PLOS Global Public Health! tinyurl.com/3ymhuj5s

Nutritional status is a key determinant of TB. In this updated systematic review and dose-response meta-analysis (43 cohorts inc > 26 million people) we redefined the relationship between body mass index (BMI) and TB. doi.org/10.1093/ije/...

At a time when global resources for #TB research, development, prevention, and care are limited, which interventions should be prioritised in high burden settings? 📢 Our new pre-print compares the impact, cost, and cost-effectiveness of 9 TB interventions in 3 countries. 1/n bit.ly/3V3vXth

Actually, Frankenstein is a doctor success at the Venice film festival

Community screening for #tuberculosis could extend the reach of #TB services, but evidence on its effectiveness is limited. In our latest preprint, we examine the epidemiological impact of trade-offs in diagnostic algorithm, population coverage, and duration of screening. 1/n bit.ly/3UK7pFD

Why I 🧡 the web. drawafish.com Just draw the fish. Trust me. 🐟

Our work estimating the potential impacts of reductions in international donor funding for #TB is now out in @lancetgh.bsky.social: bit.ly/3TDl28T @raclark18.bsky.social @cfmcquaid.bsky.social @alexandra-richards.bsky.social @top-j.bsky.social @reinhouben.bsky.social @richardwhite321.bsky.social

Wrapping up the #CausalIntroCourse.

New systematic review led by @hannahrickman.bsky.social shows annual risk of Mycobacterium #tuberculosis conversion in men and women diverges during adolescence and remains higher among men throughout adulthood. www.thelancet.com/journals/lan...

In our latest personal view in @lancetrespirmed.bsky.social, we argue for the inclusion asymptomatic #tuberculosis in vaccine trial endpoints to potentially reduce the size, length, and cost of trials. doi.org/10.1016/S221... @lshtm-tbmod.bsky.social @tb-lshtm.bsky.social

Kicking off the #CausalIntroCourse in Leeds. Hoping this will finally give me the tools to convince my mum that walking around the house barefoot ^^doesn’t^^ cause a cold.

The facts are simple and devastating: Aid cuts have already cost lives, and the number of deaths will continue to rise. Here’s the evidence. ​

LSHTM's Director writes to UK Government about #Gaza public health catastrophe Professor Liam Smeeth's letter to the Prime Minister & Foreign Secretary urges action to prevent a greater #PublicHealth disaster: 👉 www.lshtm.ac.uk/newsevents/n...

Can you believe it’s already been 25 years!? Come join us on 20 June 2025 at 4pm UK time to celebrate the 25th anniversary of the Introduction to #Infectious Disease #Modelling course delivered by @lshtm.bsky.social and @ukhsa.bsky.social! More info 👉 www.lshtm.ac.uk/newsevents/e...

TB & climate change: @who.int report out now, building on an analytical framework we developed to explore the intersections and implications for the TB epidemic. Key message? TB should be considered a climate-sensitive disease www.who.int/publications...

I fully moved to Bluesky when we @weratedogs.com made it here. This is why.

Amid all the bad news in Global Health, perhaps some good news? A first analysis on the risk of false positive diagnoses in community-screening for tuberculosis using Xpert shows our clinic-based data is likely (very) wrong and overestimates false positives by >80%: tinyurl.com/yfecute9.

Are you interested in #TB and have experience in #modelling infectious diseases? Come join us in the TB Modelling Group at #LSHTM! We're advertising for a 1 year Research Fellow position, with a closing date of 30 May 2025 👉 jobs.lshtm.ac.uk/vacancy.aspx...

Audience vote in #Eurovision. What. The. Fuck?

#Tuberculosis prevention and care relies heavily on international donor funding in many settings. In our latest preprint, we examine the potential impact of reductions in international donor funding for #TB - by the US and by other major donor countries. 1/8 www.medrxiv.org/content/10.1...

New pre-print modelling impact of US funding cuts on HIV, #TB, MCH and family planning. We estimate impact of termination of US funding to NTPs via #USAID & The Global Fund may lead to 2.2 (1.5-2.9) million excess TB deaths between 2025 and 2040, reversing over a decade of progress. bit.ly/4lowp18

On the anniversary of the sinking of the Titanic, we thought we'd answer a question that's often asked, "If they raised the Mary Rose, why not raise the Titanic?" Allow our scaled diagram to explain...

Climate-driven migration and displacement and their potential impact on TB in Latin America gh.bmj.com/content/10/4... @cfmcquaid.bsky.social @reinhouben.bsky.social @lshtm-tbmod.bsky.social

Great to be able to finally get this work out, closing out my time with @lshtm-tbmod.bsky.social

A year ago, I was tasked with creating a timeline for @lshtm-tbmod.bsky.social and we came across this amazing example of a way to keep track of a group with a long history. We now have a record of our history going back to 2011, and I hope that this can stay alive and continuously updated as well!

Update: Passed, with minor corrections (2 typos and a table to add)

PhD opportunity @lshtm-tbmod.bsky.social modelling intersection of TB (world #1 infectious killer) & climate change. Do apply to be part of a great group doing impactful work! www.lshtm.ac.uk/study/fees-a... @lshtm.bsky.social @cmmid-lshtm.bsky.social @reinhouben.bsky.social @laragosce.bsky.social

Hot off the press! 🔥 Our new systematic review digs deep into #TB cluster randomised trials, exploring how contamination can influence results, and offers insights for improving trial design #TBSky #IDSky #MedSky doi-org.ez.lshtm.ac.uk/10.5588/ijtl...

Reducing #TB burden requires understanding local contexts. Our new preprint emphasizes the importance of considering social contact patterns for interventions like active case finding, infection prevention & control, & cluster trial design #TBsky #IDsky #GlobalHealth www.medrxiv.org/content/10.1...

📣 New publication in #AIDS led by Tom Sumner estimating the impact of new TB #vaccines on the burden of TB in PLHIV in #SouthAfrica 🇿🇦 @cmmid-lshtm.bsky.social @lshtm-tbmod.bsky.social @richardwhite321.bsky.social Read the full paper now 👉 tinyurl.com/ezhc9ppx

Nutritional care for TB-affected households is likely to be highly cost-effective & could avert a substantial amount of disease and death in India – our paper out now in Lancet Global Health @raclark18.bsky.social @reinhouben.bsky.social @lshtm-tbmod.bsky.social www.sciencedirect.com/science/arti...

New preprint (with all pre-print caveats!) tinyurl.com/589ffhu4 on Mtb infection risk by sex & age. Men are at higher risk of #tuberculosis v women- but unclear how much driven by higher infection vs progression to disease. We meta-analysed Mtb immunoreactivity surveys to find out more🧵 #tbsky

I’m thrilled to share that I’ve submitted my PhD thesis at LSHTM (@lshtm.bsky.social) with the TB Modelling Group (@lshtm-tbmod.bsky.social)! The past three years have been an incredible journey, and I’m so proud of all that’s been accomplished. Excited to continue working in TB research! #TBSky

1/ 📢 In our new PREPRINT - tinyurl.com/2pmudzrk - we evaluate how symptom-agnostic, population-wide screening interventions could significantly reduce the TB burden in Viet Nam. These require a substantial front-loaded investment but yield lasting cost savings. 🧵 #Tuberculosis #TBSky

Undernutrition is a key driver of TB accounting for 1/5 cases, but relationship is poorly understood. New sys review of this based on 42 studies (>26 million people) by Matt Saunders et al: papers.ssrn.com/sol3/papers.... @reinhouben.bsky.social @raclark18.bsky.social @lshtm-tbmod.bsky.social

Our ASCENT modelling paper on Digital Adherence Technologies (DAT) for TB treatment is now out in BMJ Global Health gh.bmj.com/content/9/12... DATs may have limited epidemiological impact but can reduce costs and have important budgetary implications. @cfmcquaid.bsky.social @lshtm-tbmod.bsky.social