Our framework that informed the @who.int TB & climate change policy brief out now in @lancetrespirmed.bsky.social, exploring the intersections and implications of climate change for the TB epidemic. Key message? TB should be considered a climate-sensitive disease www.thelancet.com/journals/lan...

✨ I’m so honoured to have been awarded one of this year’s TBVI Awards! ✨ I’m truly grateful for this recognition and excited for the opportunity to showcase my research at the TBVI Annual Meeting in January 2026. #TBVI #tuberculosis #vaccines tbvi.eu/announcement...

“Wow, I saw in the last GTB report undernutrition is much less important for TB than we previously thought” I hear you say… Well, no. We think this is an underestimate, & as much as 28% of TB could be attributable to undernutrition – see our latest comment here: www.thelancet.com/journals/lan...

When fluoroquinolone resistance status is unknown, empirical use of BPaLM (adding moxifloxacin to BPaL) is cost-effective as a replacement for BPaL even with high fluoroquinolone resistance levels! 🦠💊 doi.org/10.1371/jour...

Understanding patterns of #TB exposure and transmission is needed for targeted prevention strategies. In our latest pre-print, @petedodd24.bsky.social and I estimated the proportion of TB exposure to and transmission from sex and age groups for 177 countries. bit.ly/4nbV492

We are inviting applications for postdoctoral fellows in immunology of TB at the South African Tuberculosis Vaccine Initiative, University of Cape Town. For more information see the attached ad: idm.uct.ac.za/media/739223

About half of people with #TB are asymptomatic (aTB). Calls have been made to stratify treatment and estimate incidence based on aTB case definitions In this preprint we raise concerns that symptoms are an inadequate & inconsistent classifier of TB state, being highly influenced by context ⬇️link

In a new preprint (NOT PEER REVIEWED) we continue to explore the challenge of overtreatment in community screening. It seems the benefits of TB treatment far outweigh the harms, especially once we accept that sputum culture is not perfect. Important food for thought. www.medrxiv.org/content/10.1...

PhD opportunity: New approaches to modelling TB transmission in low-incidence settings. Supervised by Ellen Brooks-Pollock (Bristol), me (Bath) & Rajeka Lazarus (Bristol) Apply: www.findaphd.com/phds/project... Deadline 20 Oct #PhD #Tuberculosis #Epidemiology #InfectiousDisease

Nice to see the latest #GlobalTBCaucus advocacy tool. This should come in handy for evidence-based fundraising as we face challenges in global health funding. www.globaltbcaucus.org/policy-and-r...

Our work on modelling population-wide screening in Viet Nam is now available in PLOS Global Public Health! tinyurl.com/3ymhuj5s

1/ It’s been 10 years (😮) since we reported that #TB prevalence was twice as high in men as in women. 📢 Our new preprint explores how sex differences have shifted with more recent national prevalence surveys and growing attention to #gender responsive TB prevention and care. bit.ly/4gqP1LH

Our systematic review of rural/urban differences in #TB prevalence shows evidence of rapidly urbanising epidemics in many settings, with differences across countries and regions. Link to preprint below ⬇️

At a time when global resources for #TB research, development, prevention, and care are limited, which interventions should be prioritised in high burden settings? 📢 Our new pre-print compares the impact, cost, and cost-effectiveness of 9 TB interventions in 3 countries. 1/n bit.ly/3V3vXth

Community screening for #tuberculosis could extend the reach of #TB services, but evidence on its effectiveness is limited. In our latest preprint, we examine the epidemiological impact of trade-offs in diagnostic algorithm, population coverage, and duration of screening. 1/n bit.ly/3UK7pFD

The Union's TB Undernutrition working group is hosting a webinar with Dr Matthew Saunders. 📅 21 August at 2pm CET Dr Saunders (@lshtm.bsky.social‬) will share findings from a new analysis that redefines the relationship between BMI and TB incidence. 📧 To join email [email protected].

Our new study examines social contact patterns in urban, peri-urban, and rural communities and their implications for #TB interventions like household contact tracing, infection prevention, and cluster RCTs. #MedSky #EpiSky #IDsky #TBSky Read more in @plosglobalpublichealth.org

Sobering study on the devastating impact of aid cuts on tuberculosis incidence and mortality in low and middle income countries Governments of highest TB burden nations will need to wake up and invest more! www.thelancet.com/journals/lan...

Reduced international donor funding through not only the termination of #USAID, but also announced reductions in donor pledges to #TheGlobalFund from other countries, could lead to substantial potential impacts on #TB morbidity and mortality. Read how in our new study in @lancetgh.bsky.social 👇

In our latest personal view in @lancetrespirmed.bsky.social, we argue for the inclusion asymptomatic #tuberculosis in vaccine trial endpoints to potentially reduce the size, length, and cost of trials. doi.org/10.1016/S221... @lshtm-tbmod.bsky.social @tb-lshtm.bsky.social

NEW STUDY! 📣 A large global study found men are more likely to be exposed to TB than women. The reason? Likely social behaviours: • More time in crowded indoor spaces • Delays in seeking care READ MORE ⤵️ 🔗 www.thelancet.com/journals/lan... @petermacp.bsky.social @hannahrickman.bsky.social

New TB research from Vietnam challenges long-held assumptions, and why does this matter? See details at this link 📍 lnkd.in/giqncDeq and below

New article just out in The Lancet Infectious Diseases! "Should people deprived of liberty be protected from research or through research?" www.sciencedirect.com/science/arti...

Huge congratulations to the 2025 LSHTM/UKHSA Infectious Disease Modelling Course Alumni. What a talented, dedicated and fun bunch of students! You were a pleasure to teach. Happy modelling! :)

Until there is a test for TB infection with higher specificity than IGRA, the use of the non-inferiority trial design for TB vaccine prevention of infection outcomes is not recommended. @richardwhite321.bsky.social @cfmcquaid.bsky.social @reinhouben.bsky.social

Tuberculosis continues to impair quality of life long after the antibiotics have finished... Need to work out how to prevent and treat these post-TB sequelae. #IDSky #TBSky

Tomorrow 🎉

Interesting and important discussion on TB drug trial endpoints by @tomyates80.bsky.social and @danieljgrint.bsky.social Describes a rare 'Win-Win' change Well worth a listen, and we'd be keen to hear your views...

Can you believe it’s already been 25 years!? Come join us on 20 June 2025 at 4pm UK time to celebrate the 25th anniversary of the Introduction to #Infectious Disease #Modelling course delivered by @lshtm.bsky.social and @ukhsa.bsky.social! More info 👉 www.lshtm.ac.uk/newsevents/e...

TB & climate change: @who.int report out now, building on an analytical framework we developed to explore the intersections and implications for the TB epidemic. Key message? TB should be considered a climate-sensitive disease www.who.int/publications...

Amid all the bad news in Global Health, perhaps some good news? A first analysis on the risk of false positive diagnoses in community-screening for tuberculosis using Xpert shows our clinic-based data is likely (very) wrong and overestimates false positives by >80%: tinyurl.com/yfecute9.

Postdoc (London, UK) Position available in the world-leading tuberculosis (TB) Modelling group at LSHTM with @raclark18.bsky.social‬ @richardwhite321.bsky.social at LSHTM @lshtm-tbmod.bsky.social More details: http://iddjobs.org/jobs/2314

👏🏼👏🏼”A graduate tested more than 18 000 people for #tuberculosis (TB)… discovering that 82% of the cases detected in the rural KwaZulu-Natal community showed no symptoms or were “sub clinical”, despite having similar bacterial levels and lung damage as symptomatic cases” @emilybethwong.bsky.social

Are you interested in #TB and have experience in #modelling infectious diseases? Come join us in the TB Modelling Group at #LSHTM! We're advertising for a 1 year Research Fellow position, with a closing date of 30 May 2025 👉 jobs.lshtm.ac.uk/vacancy.aspx...

Meeting the health needs of incarcerated people can be costly. We found that targeted #tuberculosis infection screening at 1st reception in England could be cost saving. www.sciencedirect.com/science/arti...

New pre-print on perceptions of #gender equitable norms and #TB testing history in Malawi, led by @elizabeth-digi.bsky.social with @esnightingale.bsky.social @petermacp.bsky.social Helena Feasey, Rebecca Soko, Vincent Phiri, Liz Corbett @kchorton.bsky.social www.medrxiv.org/content/10.1...

#Tuberculosis prevention and care relies heavily on international donor funding in many settings. In our latest preprint, we examine the potential impact of reductions in international donor funding for #TB - by the US and by other major donor countries. 1/8 www.medrxiv.org/content/10.1...

Reductions in contributions to The Global Fund in line with current announcements by the United States, France, the United Kingdom, and Germany may lead to an additional 699,200, 63,100, 50,500, and 30,500 TB deaths, respectively. (See table for episodes of disease and other donor countries.) 4/8

WHO recommends treatment decision scoring algorithms to help diagnose child #Tuberculosis. Thx to #Unitaid, our TB-Speed team evaluated them to be very cost-effective for children with severe acute malnutrition in UGA & ZAM www.sciencedirect.com/science/arti...

I was fortunate to attend the 2025 Global Vaccine and Immunization Research Forum (GVIRF) in Rio. It was a great meeting. I’ve jotted down some of my quick thoughts, through the lens of: could it accelerate TB vaccine development or implementation?

Modelling projects the devastating impacts of US funding cuts, including our estimates of #TB incidence and deaths @lshtm-tbmod.bsky.social @tb-lshtm.bsky.social

NHS cancer patients denied life-saving drugs due to Brexit costs In The Guardian @martinmckee.bsky.social discusses impacts of #Brexit on #cancer drugs & says it was 'inevitable that Brexit would lead to costly duplication & barriers to collaboration.' www.theguardian.com/science/2025...

Our latest pre-print led by @alexandra-richards.bsky.social shows that improving #TB treatment coverage among men to the level achieved among women could reduce morbidity and mortality in men, women, and children. Further evidence of the need for gender-responsive TB prevention and care!

Climate-driven migration and displacement and their potential impact on TB in Latin America gh.bmj.com/content/10/4... @cfmcquaid.bsky.social @reinhouben.bsky.social @lshtm-tbmod.bsky.social

New pre-print modelling impact of US funding cuts on HIV, #TB, MCH and family planning. We estimate impact of termination of US funding to NTPs via #USAID & The Global Fund may lead to 2.2 (1.5-2.9) million excess TB deaths between 2025 and 2040, reversing over a decade of progress. bit.ly/4lowp18

Great to be able to finally get this work out, closing out my time with @lshtm-tbmod.bsky.social

In 2024, 68 million people were internally displaced by humanitarian crises, & are at increased risk of TB, the world's biggest infectious disease killer. We urgently need estimates to identify the scale of this problem & drive our response. We provide initial numbers here gh.bmj.com/content/10/3...

Job opening for Director of our amazing research unit in Gambia, West Africa. Feel free to message me if you have questions, or contact the recruiters. Details in link below. Closing 2nd May. candidates.perrettlaver.com/vacancies/46...

A year ago, I was tasked with creating a timeline for @lshtm-tbmod.bsky.social and we came across this amazing example of a way to keep track of a group with a long history. We now have a record of our history going back to 2011, and I hope that this can stay alive and continuously updated as well!

It was really exciting to kick off our multi-country new TB vaccine introduction stakeholder meetings in Jakarta this week. It was a great workshop during which we learnt that the heavy metal band Metallica's current world tour is named after one of the leading TB vaccine candidates - M72 ;)