Come join the @lshtm-tbmod.bsky.social for a PhD!

Our framework that informed the @who.int TB & climate change policy brief out now in @lancetrespirmed.bsky.social, exploring the intersections and implications of climate change for the TB epidemic. Key message? TB should be considered a climate-sensitive disease www.thelancet.com/journals/lan...

“Wow, I saw in the last GTB report undernutrition is much less important for TB than we previously thought” I hear you say… Well, no. We think this is an underestimate, & as much as 28% of TB could be attributable to undernutrition – see our latest comment here: www.thelancet.com/journals/lan...

When fluoroquinolone resistance status is unknown, empirical use of BPaLM (adding moxifloxacin to BPaL) is cost-effective as a replacement for BPaL even with high fluoroquinolone resistance levels! 🦠💊 doi.org/10.1371/jour...

Nutritional status is a key determinant of TB. In this updated systematic review and dose-response meta-analysis (43 cohorts inc > 26 million people) we redefined the relationship between body mass index (BMI) and TB. doi.org/10.1093/ije/...

At a time when global resources for #TB research, development, prevention, and care are limited, which interventions should be prioritised in high burden settings? 📢 Our new pre-print compares the impact, cost, and cost-effectiveness of 9 TB interventions in 3 countries. 1/n bit.ly/3V3vXth

📯 New research from @kchorton.bsky.social and colleagues from @lshtm-tbmod.bsky.social! #TB incidence can rebound after community screening ends, meaning the gains made during a program can be erased in the years that follow. This highlights a major challenge in sustaining impact #EndTB #EpiSky

Scientists’ role in defending democracy www.science.org/doi/10.1126/...

Our work estimating the potential impacts of reductions in international donor funding for #TB is now out in @lancetgh.bsky.social: bit.ly/3TDl28T @raclark18.bsky.social @cfmcquaid.bsky.social @alexandra-richards.bsky.social @top-j.bsky.social @reinhouben.bsky.social @richardwhite321.bsky.social

Our new study examines social contact patterns in urban, peri-urban, and rural communities and their implications for #TB interventions like household contact tracing, infection prevention, and cluster RCTs. #MedSky #EpiSky #IDsky #TBSky Read more in @plosglobalpublichealth.org

Great op-ed @usatoday.com from longtime TB Fighter Quinn Yates: www.usatoday.com/story/opinio...

New systematic review led by @hannahrickman.bsky.social shows annual risk of Mycobacterium #tuberculosis conversion in men and women diverges during adolescence and remains higher among men throughout adulthood. www.thelancet.com/journals/lan...

In our latest personal view in @lancetrespirmed.bsky.social, we argue for the inclusion asymptomatic #tuberculosis in vaccine trial endpoints to potentially reduce the size, length, and cost of trials. doi.org/10.1016/S221... @lshtm-tbmod.bsky.social @tb-lshtm.bsky.social

Tuberculosis still kills around 1.3 million people every year. It was once a massive killer in Europe and the US, but not anymore. How did these countries manage to tackle it? Our first article on TB in a three-part series: ourworldindata.org/tuberculosis...

TB & climate change: @who.int report out now, building on an analytical framework we developed to explore the intersections and implications for the TB epidemic. Key message? TB should be considered a climate-sensitive disease www.who.int/publications...

Can you believe it’s already been 25 years!? Come join us on 20 June 2025 at 4pm UK time to celebrate the 25th anniversary of the Introduction to #Infectious Disease #Modelling course delivered by @lshtm.bsky.social and @ukhsa.bsky.social! More info 👉 www.lshtm.ac.uk/newsevents/e...

The chest x-ray use pioneered by Alan Hart continues to be extremely important in screening for tuberculosis. Although no one accomplishes anything in isolation, I'd argue that Hart has helped saved MILLIONS of lives because chest x-rays have been so essential in driving down rates of TB globally.

Amid all the bad news in Global Health, perhaps some good news? A first analysis on the risk of false positive diagnoses in community-screening for tuberculosis using Xpert shows our clinic-based data is likely (very) wrong and overestimates false positives by >80%: tinyurl.com/yfecute9.

Come work with us at @lshtm-tbmod.bsky.social! 🏁Application closes Friday

New preprint out from @raclark18.bsky.social, @kchorton.bsky.social, and colleagues from @lshtm-tbmod.bsky.social. The sudden withdrawal of international aid risks reversing years of hard-won gains. Beyond USAID, potential funding cuts via The Global Fund could add nearly 1M #TB deaths #EpiSky

Modelling projects the devastating impacts of US funding cuts, including our estimates of #TB incidence and deaths @lshtm-tbmod.bsky.social @tb-lshtm.bsky.social

New review article Integrating genomic and spatial analyses to describe #tuberculosis transmission: a scoping review www.thelancet.com/journals/lan... #IDSky #ClinMicro #TB #OpenAccess #OA

Great to be able to finally get this work out, closing out my time with @lshtm-tbmod.bsky.social

In 2024, 68 million people were internally displaced by humanitarian crises, & are at increased risk of TB, the world's biggest infectious disease killer. We urgently need estimates to identify the scale of this problem & drive our response. We provide initial numbers here gh.bmj.com/content/10/3...

Undernutrition is the leading risk factor for TB globally, so its very exciting to see this roadmap for integrating nutrition into the care of people with TB out now in @lancetgh.bsky.social, led by the amazing @tbtakenseriously.bsky.social www.sciencedirect.com/science/arti...

It’s here! Ready to be both devastated and inspired by John Green’s "Everything is #Tuberculosis." Let's educate ourselves and demand action, understanding that knowledge is the first step towards dismantling injustice. @johngreensbluesky.bsky.social #TBSky #EndTB #EpiSky

A new analysis from my friend, Khai Tram, and his colleagues, estimates over 100,000 excess HIV-related deaths in the next year due to the current 90-day pause in PEPFAR funding. The actions of this administration are nothing short of reprehensible. Call your representatives!! #EpiSky #IDSky #MedSky

Climate change is likely to exacerbate determinants which drive TB, the world’s leading infectious disease killer. Commissioned by WHO, we developed an analytical framework outlining potential causal relationships between climate change and TB: medrxiv.org/cgi/content/... @lshtm.bsky.social @who.int

PhD opportunity @lshtm-tbmod.bsky.social modelling intersection of TB (world #1 infectious killer) & climate change. Do apply to be part of a great group doing impactful work! www.lshtm.ac.uk/study/fees-a... @lshtm.bsky.social @cmmid-lshtm.bsky.social @reinhouben.bsky.social @laragosce.bsky.social

Come do a PhD with @lshtm-tbmod.bsky.social! We have 3 TB Modelling projects, applications due 11 March: ➡️Influenza and risk of TB ➡️Climate change on TB in migrant & displaced populations ➡️Housing & infections among the homeless More info here: www.lshtm.ac.uk/study/fees-a...

A bright light in a dark moment: The price of the critical TB drug bedaquiline has now dropped to $90 per adult treatment course for TB, a 54% reduction since just 2023. This is a huge win for @tbfighters.org and the TB activism community generally. www.stoptb.org/what-we-do/f... (1/2)...

Hot off the press! 🔥 Our new systematic review digs deep into #TB cluster randomised trials, exploring how contamination can influence results, and offers insights for improving trial design #TBSky #IDSky #MedSky doi-org.ez.lshtm.ac.uk/10.5588/ijtl...

11 PhD studentships now available in Health Analytics, Epidemic Modelling and Health Economics, jointly between LSHTM, Imperial and UKHSA, to start autumn 2025. Deadline 7 March: www.lshtm.ac.uk/study/fees-a...

Reducing #TB burden requires understanding local contexts. Our new preprint emphasizes the importance of considering social contact patterns for interventions like active case finding, infection prevention & control, & cluster trial design #TBsky #IDsky #GlobalHealth www.medrxiv.org/content/10.1...

New modelling study from colleagues @lshtm-tbmod.bsky.social shows HUGE potential for new TB vaccines to reduce TB cases in people with #HIV. Vaccination regardless of HIV status could avert up to 1 MILLION cases in South Africa by 2050 #TBSky #EndTB

Celebrating the brilliant Karen Wynn Fonstad, a cartographic genius & an inspiration to women in #geography! I recently learned she was the artist behind the "Atlas of Middle-earth," which brought #Tolkien 's world to life with stunning detail. web.archive.org/web/20250114... #Cartography #GeoSky

Nutritional care for TB-affected households is likely to be highly cost-effective & could avert a substantial amount of disease and death in India – our paper out now in Lancet Global Health @raclark18.bsky.social @reinhouben.bsky.social @lshtm-tbmod.bsky.social www.sciencedirect.com/science/arti...

When I was a kid, around 1,800,000 people died every year of tuberculosis. Now, around 1,250,000 do. That's important progress. But at this current rate, it'll take a CENTURY to push TB deaths much below 500,000 per year. That's totally unacceptable for a curable, preventable disease.

New preprint from @aschwalbc.bsky.social + team shows that population-wide #TB screening in Viet Nam could dramatically reduce TB prevalence & deaths. A cost-effective 2-step strategy with chest X-rays & tests could save millions in the long run. #EndTB #PublicHealth #TBSky

Our ASCENT modelling paper on Digital Adherence Technologies (DAT) for TB treatment is now out in BMJ Global Health gh.bmj.com/content/9/12... DATs may have limited epidemiological impact but can reduce costs and have important budgetary implications. @cfmcquaid.bsky.social @lshtm-tbmod.bsky.social

Drug-resistant tuberculosis: a persistent global health concern www.nature.com/articles/s41...

Anyone else counting down the days until @johngreensbluesky.bsky.social's new book? I'm hoping it will spark a global conversation and inspire action to combat this preventable, yet deadly, disease #TB #TBSky

The LSHTM #TB Modelling Group is offering 3 #PhD studentships through the MRC LID scheme. Exciting projects, world-class mentorship. Apply now! Details in thread🧵 mrc-lid.lshtm.ac.uk @lshtm.bsky.social #TBSky

Hey #TBSky! Today is International Men's Day, and I've seen a few posts about mental health, cancers, and healthy masculinities - but nothing about tuberculosis. Did you know #TB disproportionately affects men in every region of the world? More below ⬇️

🔔 New #TB preprint from @aschwalbc.bsky.social & team. With viable Mtb infections far outpacing previous LTBI estimates, the quest for new diagnostic tools is urgently needed #endTB #TBsky

Evaluating the impact of #TB interventions is important. Our poster for #UnionConf2024 explores the effect of contamination in cluster randomised trials and potential solutions. Full paper coming out soon in #IJTLD!

Major international conferences like #TB #UnionConf2024 can be overwhelming, especially for #neurodiverse folks. The batik artists' work in the #CommunityConnect space was a beautiful and grounding reminder of the intersection between #art and #science

Honored to have presented my recent work on social contact and mobility patterns at #UnionConf2024. Where people go and who they interact with has implications for different #TB interventions

Reflecting on this year’s #TB #UnionConf2024 and am so inspired by the brilliant minds and groundbreaking research being done to combat this global health threat. Special shoutout to the TB Modelling Group @lshtm.bsky.social 🫁