In this mathematical modeling study, Alvaro Schwalb and colleagues estimate the global burden of viable Mycobacterium tuberculosis—that which can cause disease and be transmitted—to help guide disease prevention efforts 🧪 #tuberculosis #MedSky plos.io/4aqzIQV

Our new paper on strategies for implementing a potential new #TB #vaccine in South Africa is now published in @plosglobalpublichealth.org! doi.org/10.1371/jour...

Our Editor’s Choice commentary in @cidjournal.bsky.social finds that reported TB symptoms are an inadequate classifier of disease state, as they are heavily influenced by context and substantial interviewer variability, and may have alternative causes. Read more here👇🏻 doi.org/10.1093/cid/...

Still time to register! 👇 Join the #WGNV ECR Network - Virtual Coffee Corner on 4 December 2025 to network, share experiences, and talk about #TBvaccine activities of interest. 📅 Date: Thur 4 Dec 2025 🕑 Time: 9:00 am EDT / 3:00pm CET | 4:00pm SAST | 7:30 pm IST 🔗 tinyurl.com/kj7kuuft

Another successful "Intro to TB Modelling" course in Copenhagen at #WLHC2025. Over 70 joined to learn about TB modelling! Followed by the now-traditional TB Modelling and Analysis Consortium social, which was also very well-attended and a lot of fun.

#5 Mathematical modelling and clinical trial simulation of TB prevention mrc-lid.lshtm.ac.uk/2026-27-proj... with Tom Sumner, @raclark18.bsky.social & @danieljgrint.bsky.social

#3 How should countries deliver new TB vaccines when risk factors are considered? mrc-lid.lshtm.ac.uk/2026-27-proj... with @raclark18.bsky.social & @richardwhite321.bsky.social

Come join us for a PhD in the TB Modelling Group!

New comment: Tuberculosis and undernutrition: improving estimates to reinforce the policy imperative www.thelancet.com/journals/lan...

What’s a #UnionConf without the TB modelling course? Packed room again for a long day of intro to modelling. @lshtm-tbmod.bsky.social @tb-mac.bsky.social #WCLH2025 #TBSky

Perhaps the most important collaboration at #UnionConf2025? WHO STOP TB’s Hello Kitty met the LSHTM TB Modelling Group’s bunny mascot “Bugs” today 🐰 Shout out to @stoptb.bsky.social and @lshtm-tbmod.bsky.social for making TB epidemiology both rigorous and accessible. #EndTB #WCLH2025

Our framework that informed the @who.int TB & climate change policy brief out now in @lancetrespirmed.bsky.social, exploring the intersections and implications of climate change for the TB epidemic. Key message? TB should be considered a climate-sensitive disease www.thelancet.com/journals/lan...

✨ I’m so honoured to have been awarded one of this year’s TBVI Awards! ✨ I’m truly grateful for this recognition and excited for the opportunity to showcase my research at the TBVI Annual Meeting in January 2026. #TBVI #tuberculosis #vaccines tbvi.eu/announcement...

We think our recent review provides a better estimate of the RR leading to a much higher PAF, demonstrating the importance of addressing undernutrition to prevent TB. academic.oup.com/ije/article/...

“Wow, I saw in the last GTB report undernutrition is much less important for TB than we previously thought” I hear you say… Well, no. We think this is an underestimate, & as much as 28% of TB could be attributable to undernutrition – see our latest comment here: www.thelancet.com/journals/lan...

When fluoroquinolone resistance status is unknown, empirical use of BPaLM (adding moxifloxacin to BPaL) is cost-effective as a replacement for BPaL even with high fluoroquinolone resistance levels! 🦠💊 doi.org/10.1371/jour...

Understanding patterns of #TB exposure and transmission is needed for targeted prevention strategies. In our latest pre-print, @petedodd24.bsky.social and I estimated the proportion of TB exposure to and transmission from sex and age groups for 177 countries. bit.ly/4nbV492

1/ It’s been 10 years (😮) since we reported that #TB prevalence was twice as high in men as in women. 📢 Our new preprint explores how sex differences have shifted with more recent national prevalence surveys and growing attention to #gender responsive TB prevention and care. bit.ly/4gqP1LH

So...what would happen to the global TB epidemic if we hypothetically "eliminated" undernutrition? In this preprint, we combined estimates from our new review (doi.org/10.1093/ije/...) with population-specific BMI distributions to find out...(doi.org/10.1101/2025...)

Nutritional status is a key determinant of TB. In this updated systematic review and dose-response meta-analysis (43 cohorts inc > 26 million people) we redefined the relationship between body mass index (BMI) and TB. doi.org/10.1093/ije/...

At a time when global resources for #TB research, development, prevention, and care are limited, which interventions should be prioritised in high burden settings? 📢 Our new pre-print compares the impact, cost, and cost-effectiveness of 9 TB interventions in 3 countries. 1/n bit.ly/3V3vXth

Community screening for #tuberculosis could extend the reach of #TB services, but evidence on its effectiveness is limited. In our latest preprint, we examine the epidemiological impact of trade-offs in diagnostic algorithm, population coverage, and duration of screening. 1/n bit.ly/3UK7pFD

Our new study examines social contact patterns in urban, peri-urban, and rural communities and their implications for #TB interventions like household contact tracing, infection prevention, and cluster RCTs. #MedSky #EpiSky #IDsky #TBSky Read more in @plosglobalpublichealth.org

Reduced international donor funding through not only the termination of #USAID, but also announced reductions in donor pledges to #TheGlobalFund from other countries, could lead to substantial potential impacts on #TB morbidity and mortality. Read how in our new study in @lancetgh.bsky.social 👇

Our work estimating the potential impacts of reductions in international donor funding for #TB is now out in @lancetgh.bsky.social: bit.ly/3TDl28T @raclark18.bsky.social @cfmcquaid.bsky.social @alexandra-richards.bsky.social @top-j.bsky.social @reinhouben.bsky.social @richardwhite321.bsky.social

New systematic review led by @hannahrickman.bsky.social shows annual risk of Mycobacterium #tuberculosis conversion in men and women diverges during adolescence and remains higher among men throughout adulthood. www.thelancet.com/journals/lan...

In our latest personal view in @lancetrespirmed.bsky.social, we argue for the inclusion asymptomatic #tuberculosis in vaccine trial endpoints to potentially reduce the size, length, and cost of trials. doi.org/10.1016/S221... @lshtm-tbmod.bsky.social @tb-lshtm.bsky.social

Happening tomorrow! Come join us!

TB & climate change: @who.int report out now, building on an analytical framework we developed to explore the intersections and implications for the TB epidemic. Key message? TB should be considered a climate-sensitive disease www.who.int/publications...

Can you believe it’s already been 25 years!? Come join us on 20 June 2025 at 4pm UK time to celebrate the 25th anniversary of the Introduction to #Infectious Disease #Modelling course delivered by @lshtm.bsky.social and @ukhsa.bsky.social! More info 👉 www.lshtm.ac.uk/newsevents/e...

Amid all the bad news in Global Health, perhaps some good news? A first analysis on the risk of false positive diagnoses in community-screening for tuberculosis using Xpert shows our clinic-based data is likely (very) wrong and overestimates false positives by >80%: tinyurl.com/yfecute9.

Postdoc (London, UK) Position available in the world-leading tuberculosis (TB) Modelling group at LSHTM with @raclark18.bsky.social‬ @richardwhite321.bsky.social at LSHTM @lshtm-tbmod.bsky.social More details: http://iddjobs.org/jobs/2314

Are you interested in #TB and have experience in #modelling infectious diseases? Come join us in the TB Modelling Group at #LSHTM! We're advertising for a 1 year Research Fellow position, with a closing date of 30 May 2025 👉 jobs.lshtm.ac.uk/vacancy.aspx...

🙋Interested in finding out about #vaccine hesitancy?💉 Join us for our Annual Lecture on Monday 19 May for an opportunity to hear from Prof Stephan Lewandowsky @bristolunipsych.bsky.social & network with colleagues @lshtm.bsky.social & the Vaccine Centre.🍹🤝 👉 www.lshtm.ac.uk/newsevents/e...

Our first #WorldImmunizationWeek podcast episode is live now! Tune in to hear from @emprestige.bsky.social about their journey from MSc to PhD @lshtm.bsky.social. They also share insider tips on the best lunch spots in central London, so don't miss this. soundcloud.com/user-7893872...

Reductions in contributions to The Global Fund in line with current announcements by the United States, France, the United Kingdom, and Germany may lead to an additional 699,200, 63,100, 50,500, and 30,500 TB deaths, respectively. (See table for episodes of disease and other donor countries.) 4/8

#Tuberculosis prevention and care relies heavily on international donor funding in many settings. In our latest preprint, we examine the potential impact of reductions in international donor funding for #TB - by the US and by other major donor countries. 1/8 www.medrxiv.org/content/10.1...

Modelling projects the devastating impacts of US funding cuts, including our estimates of #TB incidence and deaths @lshtm-tbmod.bsky.social @tb-lshtm.bsky.social

🗓️ Coming up in May! We are excited to welcome David Miles for our next seminar. This will cover a brief history of vaccinology, from Edward Jenner's first smallpox #vaccination to modern vaccine technology. 🗓️ 8 May ⏲️ 12.50 BST 📍LSHTM | Online 🔗 www.lshtm.ac.uk/newsevents/e...

New pre-print modelling impact of US funding cuts on HIV, #TB, MCH and family planning. We estimate impact of termination of US funding to NTPs via #USAID & The Global Fund may lead to 2.2 (1.5-2.9) million excess TB deaths between 2025 and 2040, reversing over a decade of progress. bit.ly/4lowp18

Climate-driven migration and displacement and their potential impact on TB in Latin America gh.bmj.com/content/10/4... @cfmcquaid.bsky.social @reinhouben.bsky.social @lshtm-tbmod.bsky.social

📢 Learn to model infectious diseases & inform public health decisions @lshtm.bsky.social This hands-on course equips health professionals, researchers, and policymakers with essential epidemiological modelling skills. 📅 16–27 June 2025 | Hybrid Apply now 👇 🔗 bit.ly/4iE45py

👋 Meet Brendan Wren, one of our LSHTM Vaccine Centre Co-Directors. Find out more about Brendan's lab-based #research, the current "golden era" of #vaccine development and the role of @lshtm.bsky.social as a global leader in #PublicHealth. 👉 www.lshtm.ac.uk/research/cen...

👋Meet Edward Parker! Ed is Co-Director of the @lshtm.bsky.social Vaccine Centre. In this spotlight he tells us about his #vaccine #research, what he likes doing outside work and why he didn't end up with a career in tropical forest ecology.💉🌲 Find out more 👇 www.lshtm.ac.uk/research/cen...

In 2024, 68 million people were internally displaced by humanitarian crises, & are at increased risk of TB, the world's biggest infectious disease killer. We urgently need estimates to identify the scale of this problem & drive our response. We provide initial numbers here gh.bmj.com/content/10/3...

#WorldTBDay tomorrow, don't miss our joint WTBD Symposium with @ucltb.bsky.social You may still be able to join us in person www.eventbrite.co.uk/e/world-tb-d... or if not, online. It's going to be an amazing event! #WTBD2025 #Commit #Invest #Deliver

@lshtm-tbmod.bsky.social @tb-lshtm.bsky.social @cmmid-lshtm.bsky.social

Reminder for the #LSHTM #VaccineCentre seminar happening tomorrow! 👇🏻

Climate change is likely to exacerbate determinants which drive TB, the world’s leading infectious disease killer. Commissioned by WHO, we developed an analytical framework outlining potential causal relationships between climate change and TB: medrxiv.org/cgi/content/... @lshtm.bsky.social @who.int

Please join us next week for the February #LSHTMVaccineCentre seminar! Featuring talks by Dr Allison Portnoy (@aportnoy.bsky.social) & Dr Kayoko Shioda from @busph.bsky.social on reaching #zero-dose children and target trial emulation 📆 Thurs 27 Feb 🕗 14–15:00 GMT 📍 Online tinyurl.com/23x2z4an