Laura Kiessling
@laurakiessling.bsky.social
๐ค 3409
๐ฅ 786
๐ 33
Chemical biologist at MIT, passionate about glycoscience and all chemical biology
Fun collaboration with
@thexavierlab.bsky.social
and Ribbeck groups to figure out how this human lectin plays multiple roles in controlling the
#microbiome
: stabilizing the mucus barrier and reducing bacteria that breach it.
news.mit.edu/2026/protein...
#glycotime
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2 days ago
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This meeting should be very fun as the program is quite diverse. (Even chemical biologists).
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4 days ago
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Laura Kiessling
The Welch Foundation
3 months ago
Join us for the 2025 Welch Conference on Chemical Research, โNew Horizons in Drug Discovery,โ Oct. 27-28 in-person or virtually. The event is completely free! Find more information here:
welch1.org/conference/c...
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Conference Overview
https://welch1.org/conference/conference-overview
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Laura Kiessling
The Welch Foundation
4 months ago
Donโt miss Pamela Bjorkmanโs keynote address at the 2025 Welch Conference about the need to combat future SARS-CoV-2 variants and new spillovers of SARS-like betacoronaviruses. Join in-person or virtually here:
welch1.org/conference/r...
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Register for the 2025 Welch Conference
https://welch1.org/conference/registration
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Looking forward to a great
#chembio
program hosted by
@thewelchfoundation.bsky.social
and organized by Kevan Shokat
welch1.org/conference/c...
. Great coincidence that Welch honorees are Stuart Schreiber and Pete Schultz.
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2025 Conference Program
https://welch1.org/conference/conference-program
3 months ago
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Stephan Hacker
3 months ago
Amazing news that the 5th Virtual
@chembiotalks.bsky.social
attracted 450 participants from 50 countries. If you are as excited as we are, already mark next year's date (29th of September, 2026) in your calendars and make sure to suggest your favorite speakers!
#ChemSky
#ChemBio
#DrugDiscovery
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Laura Kiessling
Polly Fordyce
3 months ago
Come join us at
@stanford-chemh.bsky.social
! I feel incredibly lucky to have launched my career here -- it is a fantastic place to do bold interdisciplinary science surrounded by creative & supportive colleagues. Applications are due 10/15/2025 -- DM me if you have questions about the search!
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Milena Schuhmacher
5 months ago
We are hiring! If you are looking for a postdoc position and you are interested in signaling lipids and proteomics, come join us in beautiful Switzerland! More information on
www.epfl.ch/labs/gr-schu...
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Open positions
GR-SCHUHMACHER
https://www.epfl.ch/labs/gr-schuhmacher/open-positions/
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Looking forward to talking today about some new ways of looking at what human lectins do.
#FallACS2025
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5 months ago
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We are so grateful for resources to help us test key ideas about glycans and
#Alzheimers
disease.
#glycotime๐งช
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7 months ago
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Laura Kiessling
Science in Boston
7 months ago
To overcome challenges that
#neurodegenerative
diseases pose, MITโs Aging Brain Initiative has awarded seed grants for 5 innovative research projects. Congrats to Drs. Joseph Coughlin, Giovanni Traverso, Pattie Maes, Bin Zhang,
@laurakiessling.bsky.social
&
@eboyden3.bsky.social
!
bit.ly/4mVasaV
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Laura Kiessling
Peter Kenny
8 months ago
Opportunity in fragment-based design at Lilly (job available in 4 locations | UK: Bracknell | USA: Boston MA, Louisville CO, San Francisco CA) ref: R-86733
#FBD
#FBDD
#FBLD
#CADD
#CompChem
#cheminformatics
#ChemJobs
#UKChemJobs
#chemsky
๐งช
careers.lilly.com/us/en/job/R-...
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Advisor - Fragment-based Computational Design in Bracknell, United Kingdom | Research & Development at Lilly
Apply for Advisor - Fragment-based Computational Design job with Lilly in Bracknell, United Kingdom. Research & Development at Lilly
https://careers.lilly.com/us/en/job/R-86733/Advisor-Fragment-based-Computational-Design/
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Laura Kiessling
Jeremy Berg
8 months ago
Brief victory celebration and NEW ASSIGNMENT More than 27,000 comments posted regarding Schedule F implementation! 1/n
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Laura Kiessling
Polly Fordyce
8 months ago
Are you a postdoc/grad student preparing to launch a faculty search? Do you have a track record of excellence in research, leadership, mentorship & community engagement? Apply to the 2025 Next Generation Faculty Symposium:
www.berkeleystanfordnextgensymposium.com
! Pls repost! (1/3)
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Stanford.Berkeley.UCSF Next Generation Faculty Symposium
https://www.berkeleystanfordnextgensymposium.com
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Lead author
@ssmelyansky.bsky.social
spearheaded a strategy to label a single sulfur-containing glycan called ManLAM on the cell envelope of the bacteria that cause
#TB
.
news.mit.edu/2025/new-mol...
or here:
www.pnas.org/doi/10.1073/...
๐งช
#glycotime
@mitchemistry.bsky.social
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New molecular label could lead to simpler, faster tuberculosis tests
MIT chemists found a way to identify a complex sugar molecule in the cell walls of Mycobacterium tuberculosis, the worldโs deadliest pathogen. This labeling could lead to simpler, faster TB tests.
https://news.mit.edu/2025/new-molecular-label-could-lead-simpler-faster-tuberculosis-tests-0505
9 months ago
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We are so excited to see the cool science that will come out of your group
#chemsky
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9 months ago
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Laura Kiessling
Jeremy Berg
9 months ago
ACTION ITEM-----ACTION ITEM Implementation of Schedule F This is what a lot of us have been worried about. This allows for many civil service positions to replaced with political appointees. This could include NIH institute directors and even POs. BUT THERE IS A COMMENT PERIOD... 1/n
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Laura Kiessling
Scott Delaney
9 months ago
๐ We need your help ๐ The government continues to cancel grants at both NIH and NSF to censor science it doesn't like. We're tracking terminations to organize and advocate. Please report your terminated grants: NIH:
forms.gle/J2znQ7y7YpeP...
NSF:
airtable.com/appGKlSVeXni...
w/
@noamross.net
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Laura Kiessling
GlycoNet
11 months ago
Weโre thrilled to feature an incredible lineup of plenary speakers at
#Glyco27
! These experts will share cutting-edge insights and the latest advancements in glycomics across areas of health, including immunology, neuroscience and more! Register today:
glyco27.org/en/begin
@glycotime.bsky.social
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These kinds of cuts are taking place when
#TB
rates are rising, including in the US. They dovetail with USAID cuts to
#TB
programs.
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9 months ago
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Laura Kiessling
Tami Lieberman
10 months ago
Job opportunity in SF to work at a small startup with the first PhD graduate of the Lieberman Lab!
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A new means of selectively imaging the inner mycolate of mycobacteria using a compound that covalently modifies an enzyme intercepts to create a new intermediate with the Kim lab,
@thebrysonlab.bsky.social
and the Bernhardt lab.
#TB
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10 months ago
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Laura Kiessling
11 months ago
Thanks to Ratmir Derda we have an articulate reply to:
www.science.org/doi/10.1126/...
putting glycans back into the picture!
@laurakiessling.bsky.social
@anneimb.bsky.social
@carolynbertozzi.bskyverified.social
@molinarotony.bsky.social
@dbojar.bsky.social
@siglecdude.bsky.social
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Confronting risks of mirror life
Broad discussion is needed to chart a path forward
https://www.science.org/doi/10.1126/science.ads9158
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This is really beautiful research showing how the glycocalyx changes with aging and its impact on the blood-brain barrier.
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11 months ago
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Laura Kiessling
Science Homecoming
11 months ago
For the Idaho Statesman ๐ฅ, Professor Melanie Samuel explains how science funding drives cures for diseases like Alzheimerโs and cancerโ and the devastating impact of mass firings in Health & Human Services. Happy Homecoming ๐งช๐งฌ๐ฌ๐
www.idahostatesman.com/opinion/read...
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Laura Kiessling
Jennifer Kohler
11 months ago
Catherine Grimes (University of Delaware) Laura Kiessling (MIT)
@laurakiessling.bsky.social
Apply now on the GRC website!
#glycotime
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Laura Kiessling
Rebecca D. Burdine, PhD
11 months ago
Make sure you, your trainees, and anyone else who might listen to you understands what "indirects" actually are, how they are established, and what Universities contribute. H/T
@rodallab.bsky.social
Please share widely!
www.youtube.com/watch?v=yxTD...
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Facilities and Administrative (F&A) Costs Explainer
YouTube video by Association of American Universities
https://www.youtube.com/watch?v=yxTDlFvkvio
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Laura Kiessling
Jacob Corn
12 months ago
Cells are filled with toxic stuff that damages healthy proteins. Is that garbage just left to rot on the curb? No way! Ubiquitin ligases have evolved to recognize chemical damage and clean it up!
www.nature.com/articles/s41...
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C-terminal amides mark proteins for degradation via SCFโFBXO31 - Nature
SCFโFBXO31 scans proteins for C-terminal amidation and marks them for subsequent proteasomal degradation.
https://www.nature.com/articles/s41586-024-08475-w
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Jess Piper
12 months ago
If you would like to see how much economic activity and grants and how many people are employed through NIH in your state, just use this handy website. And then contact your Congressional Rep and tell them to prioritize NIH.
www.unitedformedicalresearch.org/nih-in-your-...
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NIH In Your State - United For Medical Research
Select a state on the map to see the impact of NIH funding across America.
https://www.unitedformedicalresearch.org/nih-in-your-state/
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Laura Kiessling
Vaughn Cooper
12 months ago
I am confident that scientific societies will play an unusually important role in the coming years. If you are a microbiologist of any kind, please consider joining
@asm.org
if you haven't already. There are many ways to get involved, including advocacy. To learn more:
asm.org/About-ASM/Vo...
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Volunteer With ASM | Overview
ASM volunteer opportunities range from speaking with legislators about funding research during ASM's annual Hill Day, to writing articles for asm.org, to serving on committees and the Board of Directo...
https://asm.org/About-ASM/Volunteer-With-ASM/Volunteer-With-ASM
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Laura Kiessling
EMBL Events
12 months ago
๐จ Registration is now open! ๐จ Join us for 'Seeing is believing: imaging the molecular processes of life', where cutting-edge imaging methods meet groundbreaking biological discoveries. ๐#EESImaging ๐ 8 โ 11 October 2025 ๐ Submit your abstract by 2 July! ๐
https://s.embl.org/ees25-09-bl
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Laura Kiessling
Kasia Siudeja
about 1 year ago
6 more weeks to apply ! Become our new colleague at the Cell Biology Dpt and join the growing group of junior teams of
@i2bcparissaclay.bsky.social
shaping the scientific environment of the institute. Apply if you are looking for a place to start a lab or forward to any potential candidates.
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Laura Kiessling
Caltech
about 1 year ago
Please consider making a contribution to this special fund that will be used by Caltech and JPL to directly support affected individuals and their families greatly impacted by this week's devastating fires in Southern California.
giving.caltech.edu/areas-to-sup...
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Laura Kiessling
Stephan Hacker
about 1 year ago
If you are interested in ๐๐ฐ๐๐ถ๐๐ถ๐๐-๐๐ฎ๐๐ฒ๐ฑ ๐ฃ๐ฟ๐ผ๐๐ฒ๐ถ๐ป ๐ฃ๐ฟ๐ผ๐ณ๐ถ๐น๐ถ๐ป๐ด, definitely consider the
#ABPP2025
conference on March 30th to April 2nd, 2025, at The Francis Crick Institute. Registration deadlines have been updated.
www.linkedin.com/posts/14th-i...
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14th International Activity Based Protein Profiling (ABPP) Meeting on LinkedIn: REGISTRATIONS DEADLINES UPDATE! Early Bird registration (๐ฃ) has beenโฆ
REGISTRATIONS DEADLINES UPDATE! Early Bird registration (๐ฃ) has been extended to the 30th of January and Late Registrations (๐ฆ) end on the 28th of Februaryโฆ
https://www.linkedin.com/posts/14th-international-activity-based-protein-profiling-abpp-meeting_registrations-deadlines-update-early-bird-activity-7282842161870483457-t93g?utm_source=share&utm_medium=member_desktop
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Laura Kiessling
Abhishek Chatterjee
about 1 year ago
Here is a chembio starter pack I made recently:
bsky.app/profile/ache...
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Thinking about the cool
#chemistry
all those understudied bacterial species do
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about 1 year ago
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Just listened to a fantastic talk on harnessing evolution to do new
#chemistry
by
@francesarnold.bsky.social
at the Bowei Research Conference in Taiwan. Loved her advice: โNature does not care about your calculations.โ
about 1 year ago
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Magnetic Resonance News
about 1 year ago
Memorial Tribute to Alex Pines on January 13, 11 am EST / 5 pm CET, online, zoom information to be posted at
ismar.org
on January 12, please contact Rob Tycko if you would like to contribute, for more information ->
listes.services.cnrs.fr/wws/arc/nmr/...
posted 12/26/2024
#NMRchat
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Really enjoyed the opportunity to have the
@kiesslinglab.bsky.social
collaborate with the Imperiali Group on exploring human lectin interactions with glycans.
#glycotime
Some initial findings are here:
www.biorxiv.org/content/10.1...
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Glycan analysis probes inspired by human lectins for investigating host-microbe crosstalk
Human lectins are critical carbohydrate-binding proteins that recognize diverse glycoconjugates from microorganisms and can play a key role in host-microbe interactions. Despite their importance in im...
https://www.biorxiv.org/content/10.1101/2024.12.24.630132v1
about 1 year ago
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Helpful time-saving advice
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about 1 year ago
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Laura Kiessling
M. S. AtKisson
about 1 year ago
Happy Saturday. If you're working on your NIH specific Aims for a February submission, don't include a figure.
grants.nih.gov/grants-proce...
.
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Format Attachments | Grants & Funding
https://grants.nih.gov/grants-process/write-application/how-to-apply-application-guide/format-attachments#:~:text=Figures%20should%20be%20included%20in,to%20categorize%20awards%20in%20RePORT
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Women in TPD & Induced Proximity
about 1 year ago
HAPPY HOLIDAYS and EXCITING NEWS!!! We are offering two conference scholarships for 2025 to early career scientists! One for the Keystone Proximity-Based Therapeutics Conference and one to Frankfurt Conference on Quality Control in Life Processes. Application and details:
forms.gle/aP4n7HTujetb...
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Women in TPD & Induced Proximity Conference Scholarship Application
We are thrilled to be offering two conference scholarships in 2025 to early career members of our initiative! Each scholarship will cover the cost of registration and hotel. Awardees will be responsib...
https://forms.gle/aP4n7HTujetbkCXj7
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@kiesslinglab.bsky.social
is fortunate to have Gerard Porter as a member of our team
@mitchemistry.bsky.social
. I loved this article highlighting how the Caribbean Science Foundation is facilitating the education of talented researchers to promote innovation
www.eecs.mit.edu/a-launching-...
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A launching pad towards possibility: SPISE alumni at MIT โ MIT EECS
https://www.eecs.mit.edu/a-launching-pad-towards-possibility-spise-alumni-at-mit/
about 1 year ago
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This topic (and conclusion) is one that I have been teaching about for awhile in my organic chemistry class. The difference is that it was not within reach 10-15 years ago. This analysis is valuable for teaching.
#chemsky
๐งช
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about 1 year ago
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Cool work from the Traverso group
@mitofficial.bsky.social
news.mit.edu/2024/bioinsp...
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about 1 year ago
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Valerie Lensch of
@kiesslinglab.bsky.social
and the Johnson group reviewed different glycan-based strategies for eliciting an immune response:
academic.oup.com/glycob/artic...
#glycotime
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Glycoconjugate vaccines: platforms and adjuvants for directed immunity
Abstract. Central to immune recognition is the glycocalyx, a glycan-rich coat on all cells that plays a crucial role in interactions that enable pathogen d
https://academic.oup.com/glycob/article-abstract/34/11/cwae092/7909136?redirectedFrom=fulltext&login=false
about 1 year ago
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When I went to the
@yaleuniversity.bsky.social
#chembio
retreat, I got this cool
#glycotime
shirt. I showed it to Yale alum
@ssmelyansky.bsky.social
. The response: โThatโs so cool that they used the B. subtilis glycocalyx!โ Wow. People in
@kiesslinglab.bsky.social
recognize cells via their glycans.
about 1 year ago
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Laura Kiessling
Elisa Fadda
about 1 year ago
If you are interested or working in
#structuralbiology
, as you see any protein (yes, *any*), you should be thinking: is it glycosylated? The answer is likely to be yes! You can predict N-glycosylation sites and rebuild all types of glycans with ReGlyco
glycoshape.org
๐ Check out the example โฌ๏ธ 1/2
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Looking forward to honoring David Gin tomorrow at the
#chemicalbiology
symposium in his honor. He was an excellent organic chemist who contributed to our understanding of
#naturalproduct
#vaccine
adjuvants. We lost him way too soon.
about 1 year ago
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Laura Kiessling
Jordan Meier
about 1 year ago
Applications for the 2025 Bioorganic GRC are now live! Here is the link where you can check out the current line-up:
grc.org/bioorganic-c...
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