An interesting new study, by Clare Smith’s lab and me, here at Duke. We found that during Mtb infection, CCR6 knockout mice (on a B6 background) form necrotic pulmonary granulomas, have increased IL17 production and have sex specific differences in susceptibility. journals.asm.org/doi/10.1128/...

Antigen-stabilizable fluorescent nanobodies that become fluorescent upon binding intracellular targets enable background-free multicolor imaging and biosensing in living systems. @sdeoliveira.bsky.social www.nature.com/articles/s41...

We are recruiting postdocs to work on antimicrobial resistance and bacterial cell envelope biology. PLEASE SHARE.

We've been we've been working on this for quite a while now (hopefully published soon). Grateful to @proftracypalmer.bsky.social for concinving me & @lislowe.bsky.social that mycobacteria produce inter-bacterial toxins. Team science, led by @sambenedict5.bsky.social www.biorxiv.org/content/10.6...

All currently approved antibiotics inhibit essential cellular processes. Ever wonder if we could kill bacteria using the opposite strategy? Here, we demonstrate an alternative antibacterial strategy: lethality through pathway over-activation. www.nature.com/articles/s41... (1 out of 3)

Abi cook did the impossible and measured homeopathic amounts of metabolites in single mycobacterial infected macrophages preserving spatial information.

We are searching for a tenure-track junior faculty member. Join our collaborative research environment in the Department of Microbiology and Immunology at WCM. Please see the link to the job posting and distribute among your networks! apply.interfolio.com/181869

🎉 𝐄𝐱𝐜𝐢𝐭𝐞𝐝 𝐭𝐨 𝐬𝐡𝐚𝐫𝐞 𝐨𝐮𝐫 𝐧𝐞𝐰 𝐩𝐮𝐛𝐥𝐢𝐜𝐚𝐭𝐢𝐨𝐧 𝐢𝐧 𝐓𝐡𝐞 𝐄𝐌𝐁𝐎 𝐉𝐨𝐮𝐫𝐧𝐚𝐥! After 8 months of revision, our work is now online: shorturl.at/WHmFq We uncover a previously unrecognized way that 𝑀𝑦𝑐𝑜𝑏𝑎𝑐𝑡𝑒𝑟𝑖𝑢𝑚 𝑡𝑢𝑏𝑒𝑟𝑐𝑢𝑙𝑜𝑠𝑖𝑠 survives toxic metal stress during infection. ...

Monitoring intracellular antibiotic concentrations in real-time using allosteric biosensors https://www.biorxiv.org/content/10.64898/2026.02.05.704027v1