🚨 Registration deadline for the EACR conference on #cancerneuroscience is September 15 ‼️ Please join us in beautiful Bilbao for exciting discussions on the dialogue between the nervous system and cancer 🔬🧠 See you soon!

‪GSCN 2025 Best Publication Award goes to B. Lim, @moritzmall.bsky.social, J. Zaugg, A. Kamal @biomedizin.unibas.ch for joint publication in @naturegenz.bsky.social All infos on www.gscn.org @dkfz.bsky.social @www.helmholtz-munich.de @embl.org @mdc-berlin.bsky.social @bihatcharite.bsky.social

Den GSCN 2025 Publication of the Year Award erhält @moritzmall.bsky.social zusammen mit Bryce Lim und weiteren Co-Autoren für ihre Veröffentlichung "Active repression of cell fate plasticity by PROX1 safeguards hepatocyte identity and prevents liver tumorigenesis". 👏 @gscnoffice.bsky.social

🎉 Herzlichen Dank für den @gscnoffice.bsky.social-Preis „Publication of the Year 2025“ zu unserer @natgenet.nature.com Publikation: www.nature.com/articles/s41... Diese Auszeichnung ist echte Teamleistung—danke an alle Mitwirkenden. Auf zu den nächsten Schritten im Kampf gegen Krebs!

🚨 @dkfz.bsky.social Postdoctoral Fellowships 2025 — Postdoc opening (Mall Lab) Work at the interface of neurodevelopment, epigenetic repression & cancer neuroscience. Apply: jobs.dkfz.de/en/jobs/1679... #Postdoc #Plasticity #Neurodegeneration #CancerNeuroscience

We're seeking a PhD student passionate about ML, biology, and driving impact in healthcare! You'll be working on multi-omics factorization models for personalized medicine, co-supervised by @junyanlu.bsky.social. 👉 Project: www.helmholtz.de/assets/hidss... ✍️ Apply: hidss4health.de/application

Hands down the best meeting this year so far! Thanks for the fantastic organization @matlupien.bsky.social @shenhui1986.bsky.social Bonus was a musical finale - who said science cannot be fun :)

What keeps cancer cells in check—and can we tame them? In 2 collaborative preprints, we trace glioblastoma cell transitions in space and decode what regulates their plasticity 🧠👇 📍 Spatial & multi-omic atlas: www.biorxiv.org/content/10.1... 📍 Regulatory logic: www.biorxiv.org/content/10.1...

13/ Want to learn more? Read our regulatory paper www.biorxiv.org/content/10.1... and companion spatial multi-omics study www.biorxiv.org/content/10.1... Watch out for thread from @bayraktarlab.bsky.social on mapping conserved spatiotemporal trajectories of GB

🧠 Excited to share my main PhD project! We mapped the regulatory rules governing Glioblastoma plasticity using single-cell multi-omics and deep learning. This work is part of a two-paper series with @bayraktarlab.bsky.social @oliverstegle.bsky.social and @moritzmall.bsky.social, Preprint at end🧵👇

How does tumour heterogeneity arise? How can we predict cancer cell plasticity? In 2 new studies, we trace #glioblastoma heterogeneity to a spatial cancer cell trajectory w. multimodal cell atlassing bit.ly/4mkrWgs & predict plasticity w. snRNA/ATAC+deep learning bit.ly/3FbI6Ic 🧵

Thank you, @hlsalliance.bsky.social! Your backing lets junior teams like ours pursue fundamental, high-risk research to better understand cancer. Excited to keep advancing the frontiers together with many collaborations within the Alliance.

I am very grateful to @uniheidelberg.bsky.social and the Hella Bühler Foundation for this honour. Sharing the prize with the brilliant @venkataramanilab.bsky.social and our amazing teams makes me extremely proud. I am excited to channel this prize into the next wave of cancer-fighting ideas!

Ausgezeichnet für herausragende #Krebsforschung: Den mit 100.000 Euro dotierten diesjährigen Hella Bühler-Preis teilen sich Moritz Mall, DKFZ und Hector Institut für Translationale Hirnforschung, und Varun Venkataramani vom Universitätsklinikum Heidelberg. 👏 @moritzmall.bsky.social 👉 t1p.de/1dnqw

Vielen Dank für die große Ehrung und die starke Unterstützung durch das @dkfz.bsky.social , das Hector Institut & alle Partner! Gemeinsam treiben wir in Heidelberg die Krebsforschung voran – die spannendsten Entdeckungen kommen erst noch. 🙏🔬 #HellaBühlerPreis #TeamScience

Do you want to do your #postdoc in #cancerresearch with the most prestigious #fellowship in Europe? Apply to DKFZ Marie Skłodowska Curie MasterClasses by May 19. Projects in #cellandmolecularbiology #genomics #bioinformatics #immunology #medicaltechnology, #epidemiology. Apply here: t1p.de/nx6tu

Warum sind #Tierversuche in der #Krebsforschung notwendig? Das erklärt Andreas Trumpp, Abteilungsleiter am DKFZ und geschäftsführender Direktor HI-STEM in diesem Video von @tvvde.bsky.social.

@michael-platten.bsky.social has been selected and nominated as Ambassador for the ERC network. The @erc.europa.eu & the @ercgrantees.bsky.social launched the new Ambassadors on 28 April. This joint initiative aims to promote investment in frontier research and highlight the importance of #research.

Jedes Jahr erkranken in Deutschland etwa 500.000 Menschen an #Krebs. Das Deutsche Krebsforschungszentrum (DKFZ) widmet sich als größte biomedizinische Forschungseinrichtung in Deutschland ganz der Aufgabe, #Krebsforschung zu betreiben.

Visit us at the #AACR25 in #Chicago, where we present #CancerResearch in Germany. 👩🏽‍🔬👨🏽‍🔬 🇩🇪 📍Exhibition at booth #842 from April 27 to 30 @nct-heidelberg.bsky.social @DKTK @theaacr.bsky.social

Movement for prevention, nature for inspiration 🌿🌍 Today's @dkfz.bsky.social Lunch Walk took us to the Botanical Garden—a perfect match for #EarthWeek and our goal to promote #CancerPrevention through regular activity. Thanks to all who joined! #DKFZgeht #HealthyWorkplace #Heidelberg

🚨 Postdoc position open! Join our organoid engineering team in Heidelberg to advance disease modeling & drug testing in cancer & brain disorders using AI, single-cell tech & assembloids. 🧠 5 yrs funding (CZS) 🌐 Apply: bit.ly/heidelberg-o... #Postdoc #Organoids #Neuroscience

Want to decode #cancer & #autism with organoids, stem cells & genomics? We’re hiring PhD students @dkfz.bsky.social via the fully funded International PhD Program! 🌍 Heidelberg 🔗 www.dkfz.de/en/career/in... #PhDopportunity #CancerNeuroscience #Genomics

Join us on April 4 at 11:00 for a @dkfz.bsky.social Distinguished Lecture by Filipe Pereira from @lunduniversity-med.bsky.social: "In Vivo Dendritic Cell Reprogramming for Cancer Immunotherapy" 📍DKFZ Lecture Hall, Heidelberg. Filipe is pioneering #cellreprogramming to evolve #cancer #immunotherapy.

The #iHOME2025 conference is off to a great start at @dkfz.bsky.social! We're excited for 2 days of organoid science from our speakers, like Barbara Treutlein, Max Reichert, Joep Beumer and @kimbakjensen.bsky.social. With @jackstadt-lab.bsky.social @moritzmall.bsky.social @kimboonekamp.bsky.social

Deadline Approaching (Mar 15)! @dkfz.bsky.social Clinician-Scientist Fellowships open for applications—study #autism & brain/liver #cancer by exploring cell fate plasticity. 2-year contract with protected research time. Apply now: www.dkfz.de/clinicianscientist #CancerResearch #Neuroscience #Autism

Just 2 days left to secure one of the last 5 spots for the “International Heidelberg #Organoid Meeting (#iHOME2025)” (20+21 March 2025) at @dkfz.bsky.social , powered by @proteintech.bsky.social, Cenibra, OLS @hlsalliance.bsky.social: indico.dkfz.de/event/1249/

Great piece about our upcoming rally in the Sun-Times by @neilsteinberg.bsky.social Meet the organizers behind Chicago's Stand Up for Science Rally #standupforscience #scienceforall @standupforscience.bsky.social chicago.suntimes.com/columnists/2...

Actually, not so rare at all! #RareDiseaseDay Affecting a substantial part of human kind! Support research on rare diseases! Picture from rarediseaseday.org

🎗️On #RareDiseaseDay, we raise awareness for #MYT1L Syndrome, a rare #autism-associated disorder disrupting brain development. Our research at DKFZ, ZI, and Heidelberg University Hospital shows an epilepsy drug may help—future trials ahead! 📑 www.nature.com/articles/s41... 🎥 youtu.be/nYqNEPIOc-8?...

It was great presenting our work from @dkfz, @hi_stem_lab and UKHD about the new PROTECT project to patients at the second Polyposis day.

Great news! Marisa Karow-Falk is now a tenured professor at FAU’s Medical Faculty in the Biochemistry Department. In her reseach, Marisa focuses on neurodevelopment and stem cells, and teaches biochemistry to medical students. Congratulations, Marisa! @fau.de

If you enjoyed our @naturegenet.bsky.social paper on how PROX1 safeguards hepatocyte identity, check out the behind-the-scenes Research Briefing—both free to read: Paper: rdcu.be/d9IFg Briefing: rdcu.be/eaLYL #CellPlasticity #CancerResearch

Only 1 week left to register for the International Heidelberg Organoid Meeting (iHOME) 2025, March 20–21! Don’t miss the keynote by @kimbakjensen.bsky.social (ReNEW Copenhagen) on guiding intestinal stem cell fate in health & disease. Register now: indico.dkfz.de/event/1249/ #Organoids #StemCells

Don’t miss #iHOME2025 on March 20–21 in Heidelberg! Keynote speaker Dr. Joep Beumer (Institute of Human Biology, Basel) will share how advanced #organoid engineering reveals intestinal cell states and functions. Register for this and more by Feb 28: indico.dkfz.de/event/1249/ #Organoids #Conference

Researchers at @uniheidelberg.bsky.social discovered that #PROX1 can block #CellFate plasticity in #hepatocytes, preventing #LiverCancer in mice. @aryankamal.bsky.social @moritzmall.bsky.social 📃 @naturegenet.bsky.social - go.nature.com/3D9AYuR 🎤 - bit.ly/4k42YAG

Thrilled to announce another #iHOME2025 (Mar 20–21) keynote: Maximilian Reichert @tum.de discussing “Mapping Tumor Cell States in Pancreatic Cancer with Advanced Organoid Technology.” Hear how organoid approaches reveal key cancer plasticity mechanisms! Register here: indico.dkfz.de/event/1249/

Join iHOME 2025 (Mar 20–21 in Heidelberg) for cutting-edge organoid research spanning basic to clinical science! One of many highlights is the keynote speaker, Barbara Treutlein, ETH Zurich, discussing using single-cell tech to map organoid development. Register by Feb 28: indico.dkfz.de/event/1249/

The February issue of @naturegenet.bsky.social is live! Featuring: ✅oncofetal reprogramming in CRC ✅multiancestry GWAS of prostate antigen levels ✅in vivo screening in Huntington’s disease ✅PERFF-seq profiling rare cell states ✅barley pan-transcriptome & more! ⬇️ www.nature.com/ng/volumes/5...

📢ONLINE @naturegenet.bsky.social 📰Oncofetal reprogramming drives phenotypic plasticity in WNT-dependent colorectal cancer. By @sleemmz.bsky.social, @guccionelab.bsky.social and colleagues. ⬇️ www.nature.com/articles/s41...

#InternationalChildhoodCancerDay Support medical care and biomedical research for our vulnerable children worldwide! #Science #CancerResearch #ChildhoodCancer #OncoSky #Kinderkrebstag

So excited to announce that our study on the development and evolution of pallial cell types and structures in birds, led by @bassi-z.bsky.social, is now out in @science.org! www.science.org/doi/10.1126/...

In a collaborative study, Group Leaders Judith Zaugg (EMBL) and Moritz Mall (DKFZ) discovered a liver protein, called PROX1, that preserves cell identity and halts cancer formation in preclinical mouse models, paving the way for novel liver cancer therapies. 🧪 www.embl.org/news/science...

🔬 Key Regulators of Cell Fate Identified. Researchers from biomedizin.unibas.ch, embl.org & dkfz.bsky.social reveal that safeguard repressors like PROX1 can preserve cell identity & prevent liver cancer. Study by Aryan Kamal & Bryce Lim. 👉 🔗 www.nature.com/articles/s41... @naturegenet.bsky.social

#CellPlasticity—the ability of cells to change their identity—is vital for tissue growth and repair. But when it goes unchecked, it can fuel #cancer. Our latest study examines how to block #LiverCancer by actively suppressing plasticity. www.nature.com/articles/s41... #CancerBiology

Join the International Heidelberg Organoid Meeting 2025 🧠🫀🫁🔬March 20-21 @ Marsilius-Kolleg #Heidelberg! With exciting keynotes and abstract-selected posters & talks, iHOME will cover #cancer #organoid research from basic to clinical. Limited spots; register now: indico.dkfz.de/event/1249/